Gorden PJ, Magstadt DR, Baker AL, Arruda BL, Bell. Viral Mastitis Associated with Influenza A in Dairy Cattle. Vet Clin North Am Food Anim Pract. 2025 Apr 7:S074. Abstract
submitted by kickingbird at Apr, 10, 2025 from Vet Clin North Am Food Anim Pract. 2025 Apr 7:S074 (via https://www.sciencedirect.com/science/article/abs/pii/S07490)
n early 2024, farmers in the southwestern United States described a mysterious disease outbreak causing acute illness and milk drop. Diagnostic investigations determined this syndrome to result from H5N1 ... Tan WX, Qin SY, Yang X, Li XM, Li JH, Cao H, Jiang. Global Prevalence and Distribution of H9 Subtype of Avian Influenza Viruses in Wild Birds: Literature Review with Meta-Analysis. Vector Borne Zoonotic Dis. 2025 Apr 9. Abstract
submitted by kickingbird at Apr, 10, 2025 from Vector Borne Zoonotic Dis. 2025 Apr 9 (via https://www.liebertpub.com/doi/10.1089/vbz.2024.0111)
Background: As a natural accelerator of highly pathogenic avian influenza in wild birds, the H9 subtype of avian influenza poses a substantial threat to both humans and the poultry industry. A comprehensive ... Liu X, Balligand T, Le Gall C, Ploegh HL. A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses. Proc Natl Acad Sci U S A. 2025 Apr 15;122(15):e242. Abstract
submitted by kickingbird at Apr, 9, 2025 from Proc Natl Acad Sci U S A. 2025 Apr 15;122(15):e242 (via https://www.pnas.org/doi/10.1073/pnas.2424889122)
Influenza remains a significant public health threat. Both monoclonal antibodies and small-molecule inhibitors can target the influenza surface glycoproteins hemagglutinin (HA) or neuraminidase (NA) for ... Nooruzzaman M, Covaleda LM, de Oliveira PSB, Marti. Thermal inactivation spectrum of influenza A H5N1 virus in raw milk. Nat Commun. 2025 Apr 7;16(1):3299. Abstract
submitted by kickingbird at Apr, 9, 2025 from Nat Commun. 2025 Apr 7;16(1):3299 (via https://www.nature.com/articles/s41467-025-58219-1)
The spillover of highly pathogenic avian influenza (HPAI) H5N1 virus to dairy cows and shedding of high amounts of infectious virus in milk raised public health concerns. Here, we evaluated the decay and ... Xu S, Liu Y, Luo C, Zhou M, Wang K, Xie Q, Zhang Q. Identification and characterization of a broadly neutralizing and protective nanobody against the HA1 domain of H5 avian influenza virus hemagglutinin. J Virol. 2025 Apr 7:e0209024. Abstract
submitted by kickingbird at Apr, 8, 2025 from J Virol. 2025 Apr 7:e0209024 (via https://journals.asm.org/doi/10.1128/jvi.02090-24)
The highly pathogenic avian influenza viruses (HPAIVs) of subtype H5, particularly those of the currently circulating clades 2.3.2.1 and 2.3.4.4, are largely responsible for the sporadic human infections ... Jiang Y, Sun J, Huang F, Xie X, Wang X, Wu X, Jian. Influenza Vaccine Effectiveness among Primary and Secondary School Students in Shenzhen during the 2023/24 Influenza Season. Emerg Microbes Infect. 2025 Apr 7:2490531. Abstract
submitted by kickingbird at Apr, 8, 2025 from Emerg Microbes Infect. 2025 Apr 7:2490531 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Evidence on influenza vaccine effectiveness (VE) among children in southern mainland China remains sparse. To evaluate influenza VE among students aged 6-18 years in Shenzhen during the 2023/24 influenza ... Zhang H, Chen X, Liu D, Liu X, Ge Y, Sun Y, Zhang. Immunogenicity and protective efficacy of an inactivated bivalent vaccine containing two recombinant H1N1 and H3N2 swine influenza virus strains. Cell Mol Life Sci. 2025 Apr 7;82(1):150. Abstract
submitted by kickingbird at Apr, 8, 2025 from Cell Mol Life Sci. 2025 Apr 7;82(1):150 (via https://link.springer.com/article/10.1007/s00018-025-05674-0)
The wild-type H1N1 and H3N2 swine influenza virus (SIV) strains are unsuitable for vaccine production because of high lethality in chicken embryos and low reproductive titers. This study developed recombinant ... Wang, P., Fu, J., Cheng, L. et al. Neutralizing monoclonal antibodies as effective therapeutics and prophylactics against lethal H10N7 avian influenza infection in a mouse model. Vet Res 56, 75 (2025). Abstract
submitted by kickingbird at Apr, 7, 2025 from Vet Res 56, 75 (2025) (via https://link.springer.com/article/10.1186/s13567-025-01504-0)
The H10 subtype of avian influenza virus (AIV) is widespread in poultry worldwide and poses a significant threat to animal health. With the emergence of sporadic and fatal cases in humans infected with ... Zheng X, Cao F, Yu Y, Yu X, Zhou Y, Cheng S, Qiu X. The Ongoing Epidemics of Seasonal Influenza A(H3N2) in Hangzhou, China, and Its Viral Genetic Diversity. Viruses. 2025; 17(4):526. Abstract
submitted by kickingbird at Apr, 7, 2025 from Viruses. 2025; 17(4):526 (via https://www.mdpi.com/1999-4915/17/4/526)
This study examined the genetic and evolutionary features of influenza A/H3N2 viruses in Hangzhou (2010–2022) by analyzing 28,651 influenza-like illness samples from two sentinel hospitals. Influenza A/H3N2 ... Hu Z, Ai H, Wang Z, Huang S, Sun H, Xuan X, Chen M. Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens. NPJ Vaccines. 2025 Apr 4;10(1):67. Abstract
submitted by kickingbird at Apr, 7, 2025 from NPJ Vaccines. 2025 Apr 4;10(1):67 (via https://www.nature.com/articles/s41541-025-01115-y)
H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We ... Chen PL, Richardson RA, Rovito S, Yang G, Writt HN. Live-attenuated pandemic H1N1 influenza vaccines expressing computationally optimized broadly reactive antigens (COBRAs) are immunogenic and protective in mice and ferrets. Vaccine. 2025 Apr 4;53:127090. Abstract
submitted by kickingbird at Apr, 7, 2025 from Vaccine. 2025 Apr 4;53:127090 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Computationally optimized broadly reactive antigens (COBRAs) induce broad and protective immune responses across multiple viral vaccine platforms. However, their suitability for incorporation into live ... GIP, Global Influenza Surveillance and Response Sy. Influenza at the human-animal interface summary and assessment, 19 March 2025. WHO. Abstract
submitted by kickingbird at Apr, 6, 2025 from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 21 January to 19 March 2025, based on reporting date, the detection of influenza A(H5N1) in five humans, influenza A(H9N2) virus in four humans, influenza A(H1N1) variant ((H1N1)v) virus in one human, ... Wagoner, Zachary W. et al.. Systems immunology analysis of human immune organoids identifies host-specific correlates of protection to different influenza vaccines. Cell Stem Cell, Volume 32, Issue 4, 529 - 546.e6. Abstract
submitted by kickingbird at Apr, 6, 2025 from Cell Stem Cell, Volume 32, Issue 4, 529 - 546.e6 (via https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)0)
Vaccines are an essential tool to significantly reduce pathogen-related morbidity and mortality. However, our ability to rationally design vaccines and identify correlates of protection remains limited. ... Xiao X, Wang X, Xu F, Liang Y, Luo Y, Li S, Zhou P. Synergistic effects of PA (S184N) and PB2 (E627K) mutations on the increased pathogenicity of H3N2 canine influenza virus infections in mice and dogs. J Virol. 2025 Apr 4:e0198424. Abstract
submitted by kickingbird at Apr, 5, 2025 from J Virol. 2025 Apr 4:e0198424 (via https://journals.asm.org/doi/10.1128/jvi.01984-24)
As companion animals, dogs are susceptible to various subtypes of influenza A virus (IAV), with the H3N2 and H3N8 subtypes of canine influenza virus (CIV) stably circulating among canines. Compared to ... Arbani O, Ducatez MF, Kadja-Wonou M, Salamat F, Ki. Development of an experimental model using cold stress to assess the pathogenicity of two Moroccan AI H9N2 isolates from 2016 and 2022 in commercial broiler chickens. PLoS One. 2025 Apr 4;20(4):e0320666. Abstract
submitted by kickingbird at Apr, 5, 2025 from PLoS One. 2025 Apr 4;20(4):e0320666 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since 2016, low pathogenic avian influenza virus (LPAIV) H9N2 became a major issue for poultry production in Morocco. Even though the agent was classified as low pathogenic, AI H9N2 cause significant economic ... Claire Guinat, etc.,al. [preprint]Highly pathogenic avian influenza management in high-density poultry farming areas. https://doi.org/10.1101/2025.03.25.645233. Abstract
submitted by kickingbird at Apr, 2, 2025 from https://doi.org/10.1101/2025.03.25.645233 (via https://www.biorxiv.org/content/10.1101/2025.03.25.645233v1)
The continuous spread of highly pathogenic avian influenza H5 viruses poses significant challenges, particularly in regions with high poultry farm densities where conventional control measures are less ... Lindsey R Robinson-McCarthy, etc.,al. [preprint]Dairy cattle herds mount a characteristic antibody response to highly pathogenic H5N1 avian influenza viruses. https://doi.org/10.1101/2025.04.01.646587. Abstract
submitted by kickingbird at Apr, 2, 2025 from https://doi.org/10.1101/2025.04.01.646587 (via https://www.biorxiv.org/content/10.1101/2025.04.01.646587v1)
An unprecedented outbreak of a highly pathogenic avian influenza virus, H5 clade 2.3.4.4b, was reported in United States dairy cattle during the spring of 2024. It has now spread to hundreds of herds across ... Liu, Y., Deng, S., Ren, S. et al. Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models. Nat Commun 16, 3133 (2025). Abstract
submitted by kickingbird at Apr, 2, 2025 from Nat Commun 16, 3133 (2025) (via https://link.springer.com/article/10.1038/s41467-025-58504-z)
The highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in aquatic birds since 1997, causing outbreaks in domestic poultry and occasional human infections worldwide. Recently, the cross-species ... Johncox, E., Parmley, E.J., Sharif, S. et al. Mapping of stakeholders in avian influenza surveillance in Canada. One Health Outlook 7, 21 (2025). Abstract
submitted by kickingbird at Apr, 1, 2025 from One Health Outlook 7, 21 (2025) (via https://onehealthoutlook.biomedcentral.com/articles/10.1186/)
Introduction: Highly pathogenic avian influenza viruses are highly transmissible and lethal in wild and domestic birds and can infect other mammals. Effective avian influenza surveillance and response ... zhu-nan Li, etc.,al. [preprint]Population Immunity to Hemagglutinin Head, Stalk and Neuraminidase of Highly Pathogenic Avian Influenza 2.3.4.4b A(H5N1) viruses in the United States and the Impact of Seasonal Influenza on. https://doi.org/10.1101/2025.03.30.25323419. Abstract
submitted by kickingbird at Apr, 1, 2025 from https://doi.org/10.1101/2025.03.30.25323419 (via https://www.medrxiv.org/content/10.1101/2025.03.30.25323419v)
The unprecedented 2.3.4.4b A(H5N1) outbreak in dairy cattle, poultry, and spillover to humans in the United States (US) poses a major public health threat. Population immunity is a critical component of ... 9492 items, 20/Page, Page[47/475][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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