Badr C, Arbi M, Souiai O, Larbi I, Nsiri J, Elbehi. Tracing the 2021 equine influenza Outbreak: First characterization and phylogeographic analysis of H3N8 Florida clade 1 virus in Tunisia. Virology. 2025 Aug 12;611:110655. Abstract
submitted by kickingbird at Aug, 19, 2025 from Virology. 2025 Aug 12;611:110655 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Equine influenza (EI) is a highly contagious viral respiratory disease affecting equids, with the potential of causing widespread outbreaks across Europe, the Americas, Asia, and other regions of the world. ... Yin S, Zhang C, Teitelbaum CS, Si Y, Zhang G, Wang. Landscape changes elevate the risk of avian influenza virus diversification and emergence in the East Asian-Australasian Flyway. PNAS 2025 Aug 26;122(34):e2503427122. Abstract
submitted by kickingbird at Aug, 19, 2025 from PNAS 2025 Aug 26;122(34):e2503427122 (via https://www.pnas.org/doi/10.1073/pnas.2503427122)
Highly pathogenic avian influenza viruses (HPAIV) persistently threaten wild waterfowl, domestic poultry, and public health. The East Asian-Australasian Flyway plays a crucial role in HPAIV dynamics due ... Restrepo Munera J, Riccio-Baum C, Kaddis Maldonado. Germinal Center B cells provide essential IL-1β signals to TFH cells via canonical NLRP3 inflammasome activity post influenza infection. PLoS Pathog. 2025 Aug 18;21(8):e1013404. Abstract
submitted by kickingbird at Aug, 19, 2025 from PLoS Pathog. 2025 Aug 18;21(8):e1013404 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Persistent germinal center (GC) responses show increased benefit in optimal responses to influenza infection. Follicular helper T (TFH) cells provide the essential signals and help for maintenance of GCs ... Saeidi S, Wan H, Kang H, Gao J, Wu WW, Malik T, Da. N-linked glycans on the stalk of influenza virus neuraminidase promote functional tetramer formation by compensating for local hydrophobicity. J Virol. 2025 Aug 18:e0087925. Abstract
submitted by kickingbird at Aug, 19, 2025 from J Virol. 2025 Aug 18:e0087925 (via https://journals.asm.org/doi/10.1128/jvi.00879-25)
Enveloped virus surface antigens, such as influenza neuraminidase (NA), typically depend on N-linked glycans for assembly, trafficking in the host cell, and immune evasion. Here, we examined the function ... Basu Thakur P, Bullock HA, Stevens J, Kumar A, Mai. Heterogeneity across mammalian- and avian-origin A(H1N1) influenza viruses influences viral infectivity following incubation with host bacteria from the human respiratory tract. Microbiol Spectr. 2025 Aug 18:e0097725. Abstract
submitted by kickingbird at Aug, 19, 2025 from Microbiol Spectr. 2025 Aug 18:e0097725 (via https://journals.asm.org/doi/10.1128/spectrum.00977-25)
Influenza A viruses (IAVs) are primarily transmitted between mammals by the respiratory route and encounter bacteria in the respiratory tract before infecting susceptible epithelial cells. Previous studies ... Meseko C, Edet UO, Henshaw O, Mkpuma N, Olawuyi KA. Bibliometric analysis of highly pathogenic avian influenza research globally from 2003 to 2023. Germs. 2025 Mar 31;15(1):11-25. Abstract
submitted by kickingbird at Aug, 19, 2025 from Germs. 2025 Mar 31;15(1):11-25 (via https://www.germs.ro/en/Articles/Bibliometric-analysis-of-hi)
Introduction: Despite decades of research on highly pathogenic avian influenza, especially H5N1, an understanding of the impact of research outputs on policy, the impact of funding and policies, collaboration ... Andersen, Hanne et al. Immunopathogenesis of lethal H5N1 avian influenza virus clade 2.3.4.4b infection in macaques. Immunity. Abstract
submitted by kickingbird at Aug, 19, 2025 from Immunity (via https://www.cell.com/immunity/fulltext/S1074-7613(25)00329-2)
The H5N1 avian influenza virus clade 2.3.4.4b outbreak represents a major pandemic threat for humans, with some reported cases of severe and fatal respiratory illness. A key unanswered question is the ... Ashraf M, Stein AN, Youhanna J, Rockman S, McMahon. The impact of egg adaptation and immune imprinting on influenza vaccine effectiveness. Vaccine. 2025 Aug 13;62:127393. Abstract
submitted by kickingbird at Aug, 18, 2025 from Vaccine. 2025 Aug 13;62:127393 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Most influenza vaccines are produced in hens' eggs and may undergo 'egg adaptation', whereby mutations within the haemagglutinin protein that result in adaptation to the avian cells undergo positive selection. ... Marschik T, Sawodny S, Kopacka I, H?flechner-P?ltl. Cost assessment of a preventive vaccination program against highly pathogenic avian influenza in Austrian poultry farms. Prev Vet Med. 2025 Aug 9;244:106655. Abstract
submitted by kickingbird at Aug, 18, 2025 from Prev Vet Med. 2025 Aug 9;244:106655 (via https://www.sciencedirect.com/science/article/pii/S016758772)
The ongoing global epidemic of highly pathogenic avian influenza (HPAI) has led to the culling of millions of birds across the European Union and beyond. In response, preventive vaccination has been increasingly ... McGeoch LJ, Foulkes S, Whitaker H, Munro K, Khawam. Effectiveness of influenza vaccination against infection in UK healthcare workers during winter 2023-24: the SIREN cohort study. J Infect. 2025 Aug 13:106585. Abstract
submitted by kickingbird at Aug, 18, 2025 from J Infect. 2025 Aug 13:106585 (via https://www.journalofinfection.com/article/S0163-4453(25)001)
Objectives: To determine vaccine effectiveness against influenza infection among UK healthcare workers between 1 September 2023 and 31 March 2024.Methods: We conducted a prospective cohort study, including ... Rawi R, Morano NC, Cheung CS, Du H, Gorman J, Prab. The N terminus of H3-influenza hemagglutinin as a site-of-vulnerability to neutralizing antibody. Structure. 2025 Aug 6:S0969-2126(25)00264-3. Abstract
submitted by kickingbird at Aug, 18, 2025 from Structure. 2025 Aug 6:S0969-2126(25)00264-3 (via https://www.cell.com/structure/fulltext/S0969-2126(25)00264-)
The N terminus of the H3 subtype of influenza virus hemagglutinin is ～10 residues longer than the N termini of most other hemagglutinins. As conserved, exposed, and linear regions may be good vaccine targets, ... Thomas MN, Janzen GM, Markin A, Sharma A, Hewitt K. Active surveillance for influenza A virus in swine reveals within-farm reassortment and cocirculation of distinct subtypes and genetic clades. Vet Microbiol. 2025 Aug 11;309:110681. Abstract
submitted by kickingbird at Aug, 18, 2025 from Vet Microbiol. 2025 Aug 11;309:110681 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Influenza A virus (IAV) is one of the most frequently detected respiratory pathogens in swine. A passive surveillance system in the United States (U.S.) provides aggregated metrics to quantify spatial ... Katherine E Goodman, Seyed M Shams, Laurence S Mag. Generative Artificial Intelligence–based Surveillance for Avian Influenza Across a Statewide Healthcare System. Clinical Infectious Diseases, 2025;, ciaf369. Abstract
submitted by kickingbird at Aug, 17, 2025 from Clinical Infectious Diseases, 2025;, ciaf369 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Among all 2024 emergency department visits for acute respiratory illness or conjunctivitis across a statewide healthcare system (n = 13 494), generative artificial intelligence–based surveillance with ... Erica S Shenoy, Westyn Branch-Elliman, Jenna Wiens. The Search for the Golden Egg: Applied Large Language Models to Detect Patients With Potential Exposure to Avian Influenza. Clinical Infectious Diseases, 2025;, ciaf371. Abstract
submitted by kickingbird at Aug, 17, 2025 from Clinical Infectious Diseases, 2025;, ciaf371 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Influenza A(H5N1) viruses continue to circulate in birds, dairy cows, and other animals across the United States, with 70 human cases detected durng the 2024-2025 outbreak; most identified human cases ... Shanshan Guan, etc.,al. Optimization of the Monoclonal Antibody 3E1 through W32I Mutation Enhances Antiviral Efficacy against Influenza Virus Subtypes H1N1 and H3N2. Antiviral Research. Abstract
submitted by kickingbird at Aug, 17, 2025 from Antiviral Research (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
The influenza virus has caused a global pandemic with significant morbidity and mortality, underscoring the need to optimize antibodies for improved antiviral efficacy. The monoclonal antibody 3E1 effectively ... Lorin Adams, etc.,al. Improved Resolution of Influenza Vaccination Responses With High-Throughput Live Virus Microneutralisation. Influenza and Other Respiratory Viruses. Abstract
submitted by kickingbird at Aug, 16, 2025 from Influenza and Other Respiratory Viruses (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70140)
BackgroundInfluenza remains a significant threat to human and animal health. Assessing serological protection against influenza has relied upon haemagglutinin inhibition (HAI) assays, which are used to ... Hu, S., & Cui, J.. Cattle H5N1 Outbreak in US Driven by Cow’s ´Cross-Nursing´ Behavior: Elucidating a Novel Transmission Mechanism. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Aug, 16, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The emergence of highly pathogenic avian influenza A(H5N1) in US dairy cattle represents an unprecedented zoonotic event with critical pandemic implications. As of June 2025, over 1,070 dairy farms across ... ZHENG Mengjia, etc.,al. Investigation and Analysis of a Reported Highly Pathogenic Avian Influenza Outbreak. China Poultry Science, Vol.47 No.8 2025. Abstract
submitted by kickingbird at Aug, 16, 2025 from China Poultry Science, Vol.47 No.8 2025 (via http://www.flu.org.cn/scn/article-23700.html)
On February 10, 2025, the Shandong Animal Disease Prevention and Control Center received a report of a suspected highly pathogenic avian influenza (HPAI) outbreak at a poultry farm. To verify the authenticity ... Eduard Puente-Massaguer, etc.,al. [preprint]A clade 2.3.4.4b H5N1 virus vaccine that elicits cross-protective antibodies against conserved domains of H5 and N1 glycoprotein. https://doi.org/10.1101/2025.08.14.670375. Abstract
submitted by kickingbird at Aug, 16, 2025 from https://doi.org/10.1101/2025.08.14.670375 (via https://www.biorxiv.org/content/10.1101/2025.08.14.670375v1)
The continuous evolution and widespread dissemination of highly pathogenic avian influenza (HPAI) H5N1 viruses, particularly clade 2.3.4.4b, pose critical challenges to global pandemic preparedness. In ... Johanna Hol Fosse, etc.,al. [preprint]Detection of antibodies specific to H5 avian influenza virus in a sheep in Norway, June 2024, eleven months after an outbreak of highly pathogenic avian influenza in a nearby seabird colony. https://doi.org/10.1101/2025.08.14.670265. Abstract
submitted by kickingbird at Aug, 16, 2025 from https://doi.org/10.1101/2025.08.14.670265 (via https://www.biorxiv.org/content/10.1101/2025.08.14.670265v1)
A 2023 outbreak of highly pathogenic avian influenza in seabirds in Norway caused substantial environmental contamination of grazing areas frequented by local sheep. Eleven months later, 220 sheep were ... 9876 items, 20/Page, Page[43/494][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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