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2025-12-6 4:47:44
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US CDC. Bacterial Coinfections in Lung Tissue Specimens from Fatal Cases of 2009 Pandemic Influenza A (H1N1) --- United States, May--August 2009. MMWR Morb Mortal Wkly Rep 2009; 58 (early release).  Abstract  
submitted by kickingbird at Oct, 1, 2009 from MMWR Morb Mortal Wkly Rep 2009; 58 (early release) (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58e0929a1.htm?s_c)
In previous influenza pandemics, studies of autopsy specimens have shown that most deaths attributed to influenza A virus infection occurred concurrently with bacterial pneumonia (1), but such evidence ...

Ruth M. Parker, etc.,al. Risk of Confusion in Dosing Tamiflu Oral Suspension in Children. NEJM.  Abstract  
submitted by kickingbird at Sep, 29, 2009 from NEJM (via http://content.nejm.org/cgi/content/full/NEJMc0908840)
The medical community should be made aware of the serious potential for dosing errors in children prescribed Tamiflu (oseltamivir) oral suspension, as illustrated in the case described below. After the ...

US CDC. CDC Guidance for Responses to Influenza for Institutions of Higher Education during the 2009-2010 Academic Year. Flu.Gov.  Abstract  
submitted by kickingbird at Aug, 22, 2009 from Flu.Gov (via http://www.flu.gov/plan/school/higheredguidance.html)
This document provides guidance to help decrease the spread of flu among students, faculty, and staff of institutions of higher education (IHE) and post-secondary educational institutions during the 2009-2010 ...

MMWR. Oseltamivir-Resistant Novel Influenza A (H1N1) Virus Infection in Two Immunosuppressed Patients --- Seattle, Washington, 2009. MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4.  Abstract  
submitted by kickingbird at Aug, 16, 2009 from MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4 (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58d0814a1.htm?s_c)
Novel influenza A (H1N1) virus infection continues to cause illness and death among persons worldwide. Immunosuppressed patients with influenza virus infection can shed virus for prolonged periods, increasing ...

Amesh A. Adalja. Zanamivir Resistance in Influenza. CBN.  Abstract  
submitted by kickingbird at Aug, 14, 2009 from CBN (via http://www.upmc-cbn.org/report_archive/2009/08_August_2009/c)
Antiviral therapy against influenza always has been plagued by the development of resistance. Unfortunately, as medical management of influenza relies increasingly on antiviral therapy, drug resistance ...

DA Henderson, Brooke Courtney, Thomas V. Inglesby,. Public Health and Medical Responses to the 1957-58 Influenza Pandemic. Mary Ann Liebert, Inc.  Abstract  
submitted by kickingbird at Aug, 14, 2009 from Mary Ann Liebert, Inc (via http://www.liebertonline.com/doi/abs/10.1089/bsp.2009.0729)
As the U.S. prepares to respond this fall and winter to pandemic (H1N1) 2009, a review of the 1957-58 pandemic of Asian influenza (H2N2) could be useful for planning purposes because of the many similarities ...

Danishuddin M, Khan AU.. Phylogenetic Analysis of the Neuraminidase Gene Reveals that the H5N1 Strains Prevalent in Chickens During 2006 Bird Flu Outbreaks in Two Regions of Maharashtra, India Are Genetically Different. Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2 (via http://www.ncbi.nlm.nih.gov/pubmed/19591792?ordinalpos=39&it)
In February 2006, two outbreaks of highly pathogenic avian influenza A virus subtype H5N1 occurred in chickens in two neighboring districts (first in Nandurbar and second in Jalgaon) of Maharashtra, India, ...

van Zoelen MA, van der Sluijs KF, Achouiti A, Flor. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology. 2009 Jul 8.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Virology. 2009 Jul 8 (via http://www.ncbi.nlm.nih.gov/pubmed/19592063?ordinalpos=35&it)
Pneumonia caused by influenza A virus (IAV) can have devastating effects, resulting in respiratory failure and death. The idea that a new influenza pandemic might occur in the near future has triggered ...

Lange E, Kalthoff D, Blohm U, Teifke JP, Breithaup. Pathogenesis and transmission of the novel swine origin influenza virus A/H1N1 after experimental infection of pigs. J Gen Virol. 2009 Jul 10..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from J Gen Virol. 2009 Jul 10. (via http://www.ncbi.nlm.nih.gov/pubmed/19592456?ordinalpos=33&it)
Influenza virus A/H1N1n currently causing a pandemic contains gene segments with ancestors in North American and Eurasian swine lineages. To get insights into virus replication dynamics, clinical symptoms ...

Ilyinskii PO, Schmidt T, Lukashev D, Meriin AB, Th. Importance of mRNA Secondary Structural Elements for the Expression of Influenza Virus Genes. OMICS. 2009 Jul 13..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from OMICS. 2009 Jul 13. (via http://www.ncbi.nlm.nih.gov/pubmed/19594376?ordinalpos=28&it)
Development of novel vaccines and therapeutics often requires efficient expression of recombinant viral proteins. Here we show that mutations in essential functional regions of conserved influenza proteins ...

Husain M, Harrod KS. Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells. FEBS Lett. 2009 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from FEBS Lett. 2009 Jul 10 (via http://www.ncbi.nlm.nih.gov/pubmed/19596000?ordinalpos=24&it)
Histone deacetylase 6 (HDAC6) is a multi-substrate cytoplasmic enzyme that regulates many important biological processes. Recently, some reports have implicated HDAC6 in viral infection. However, nothing ...

Yamanaka T, Nemoto M, Tsujimura K, Kondo T, Matsum. Interspecies transmission of equine influenza virus (H3N8) to dogs by close contact with experimentally infected horses. Vet Microbiol. 2009 Jun 21..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Vet Microbiol. 2009 Jun 21. (via http://www.ncbi.nlm.nih.gov/pubmed/19596528?ordinalpos=20&it)
In horse populations, influenza A virus subtype H3N8 (equine influenza virus, EIV) is a very important pathogen that leads to acute respiratory disease. Recently, EIV has emerged in dogs, and has become ...

Chan RW, Chan MC, Wong AC, Karamanska R, Dell A, H. DAS181 Inhibits H5N1 Influenza virus Infection of Human Lung Tissues. Antimicrob Agents Chemother. 2009 Jul 13.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Antimicrob Agents Chemother. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19596886?ordinalpos=14&it)
DAS181 is a novel therapeutic candidate against influenza virus which functions via the mechanism of removing the virus receptor, sialic acid (Sia) from the adjacent glycan structures. DAS181 and its analogues ...

Lazrak A, Iles KE, Liu G, Noah DL, Noah JW, Matalo. Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species. FASEB J. 2009 Jul 13..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from FASEB J. 2009 Jul 13. (via http://www.ncbi.nlm.nih.gov/pubmed/19596899?ordinalpos=13&it)
The mechanisms by which replicating influenza viruses decrease the expression and function of amiloride-sensitive epithelial sodium channels (ENaCs) have not been elucidated. We show that expression of ...

Smith GJ, Bahl J, Vijaykrishna D, Zhang J, Poon LL. Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A. 2009 Jul 13.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Proc Natl Acad Sci U S A. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19597152?ordinalpos=12&it)
Pandemic influenza viruses cause significant mortality in humans. In the 20th century, 3 influenza viruses caused major pandemics: the 1918 H1N1 virus, the 1957 H2N2 virus, and the 1968 H3N2 virus. These ...

Vincent AL, Ma W, Lager KM, Gramer MR, Richt JA, J. Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States. Virus Genes. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Virus Genes. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19597980?ordinalpos=9&ito)
H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003-2004; antigenic and genetic characterization identified the hemagglutinin (HA) as ...

Yang W, Qu S, Liu Q, Zheng C. Avian influenza virus A/chicken/Hubei/489/2004 (H5N1) induces caspase-dependent apoptosis in a cell-specific manner. Mol Cell Biochem. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Mol Cell Biochem. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19597767?ordinalpos=10&it)
The economic damage caused by H5N1 avian influenza virus outbreak in domestic poultry and the threat of this virus to human health make the research of this virus highly significant. During the 2004 outbreak ...

Cady SD, Luo W, Hu F, Hong M.. Structure and Function of the Influenza A M2 Proton Channel. Biochemistry. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Biochemistry. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19601584?ordinalpos=7&ito)
The M2 protein of influenza A viruses forms a tetrameric pH-activated proton-selective channel that is targeted by the amantadine class of antiviral drugs. Its ion channel function has been extensively ...

Cross KJ, Langley WA, Russell RJ, Skehel JJ, Stein. Composition and functions of the influenza fusion peptide. Protein Pept Lett. 2009;16(7):766-78.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Protein Pept Lett. 2009;16(7):766-78 (via http://www.ncbi.nlm.nih.gov/pubmed/19601906?ordinalpos=5&ito)
Fusion of the influenza virus envelope with the endosomal membrane of host cells is mediated by the hemagglutinin glycoprotein (HA). The most conserved region of HA is at the N-terminus of the HA2 subunit, ...

Yan S, Wu G. Describing evolution of hemagglutinins from influenza a viruses using a differential equation. Protein Pept Lett. 2009;16(7):794-804.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Protein Pept Lett. 2009;16(7):794-804 (via http://www.ncbi.nlm.nih.gov/pubmed/19601909?ordinalpos=4&ito)
Since 1999 we have developed three approaches to quantifying each amino acid in a protein as well as a protein in whole based on random mechanisms. With our approaches, we can reliably describe the evolution ...

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