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2025-12-5 19:03:43
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Rebecca Daines, Jean-Remy Sadeyen, etc.,al. [preprint]Mapping Haemagglutinin Residues Driving Antigenic Diversity in H5Nx Avian Influenza Viruses. https://doi.org/10.1101/2025.06.18.660338.  Abstract  
submitted by kickingbird at Jun, 20, 2025 from https://doi.org/10.1101/2025.06.18.660338 (via https://www.biorxiv.org/content/10.1101/2025.06.18.660338v1)
Since its emergence in 1996, the H5 avian influenza virus (AIV) A/Goose/Guangdong/1/1996 (Gs/GD) haemagglutinin (HA) has evolved into over 30 genetically and antigenically distinct clades, including the ...

Ana Moreno, etc.,al. [preprint]nactivation of Influenza A Viruses (H1N1, H5N1) During Grana-Type Raw Milk Cheesemaking: Implications for Foodborne Transmission Risk. https://doi.org/10.1101/2025.06.18.660327.  Abstract  
submitted by kickingbird at Jun, 20, 2025 from https://doi.org/10.1101/2025.06.18.660327 (via https://www.biorxiv.org/content/10.1101/2025.06.18.660327v1)
Background: The detection of H5N1 highly pathogenic avian influenza virus (HPAIV) in lactating dairy cattle in the United States, with high viral titers in raw milk, has raised concerns about potential ...

Matthew Scotch, etc.,al. [preprint]Campus-based genomic surveillance uncovers early emergence of a future dominant A(H3N2) influenza clade. https://doi.org/10.1101/2025.06.13.25329559.  Abstract  
submitted by kickingbird at Jun, 19, 2025 from https://doi.org/10.1101/2025.06.13.25329559 (via https://www.medrxiv.org/content/10.1101/2025.06.13.25329559v)
We conducted genomic surveillance of seasonal influenza during the 2022-2023 northern hemisphere flu season on a large university setting in Southwest Arizona USA to understand the diversity, evolution, ...

Lan J, Liu L, Li X, Ding R, Zhu J, Qu F, Zhai B, W. H13N8 and H16N3 AIV Isolated From Shorebirds Can Replicate in the Rectum of Mice. J Med Virol. 2025 Jun;97(6):e70455.  Abstract  
submitted by kickingbird at Jun, 18, 2025 from J Med Virol. 2025 Jun;97(6):e70455 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70455)
To investigate the pathogenicity and cross-species transmission potential of H13 and H16-subtype of low pathogenic avian influenza viruses (LPAIVs), two strains of H13N8 and H16N3 isolated from shorebirds ...

Yue, Y., Li, Q., Chen, C. et al. Purine nucleoside phosphorylase dominates Influenza A virus replication and host hyperinflammation through purine salvage. Sig Transduct Target Ther 10, 191 (2025).  Abstract  
submitted by kickingbird at Jun, 17, 2025 from Sig Transduct Target Ther 10, 191 (2025) (via https://link.springer.com/article/10.1038/s41392-025-02272-1)
Influenza A virus (IAV) poses a significant threat to human health. The outcome of IAV results from the viral-host interaction, with the underlying molecular mechanisms largely unknown. By integrating ...

Kwon, T., Trujillo, J. D., Carossino, M., Machkove. Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. Emerging Microbes Infections, 14(1).  Abstract  
submitted by kickingbird at Jun, 17, 2025 from Emerging Microbes Infections, 14(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching 17 states and at least 1000 dairy herds in the United States. ...

Bian J, Fung J, Lee LK, Tam WY, Wong LC, Wong CK,. Genetic Characterization of Influenza A Viruses Circulating in Hong Kong, China, 2023: The first influenza epidemic after the lifting of 2.5 years of COVID-19 non-pharmaceutical interventions. Emerg Microbes Infect. 2025 Jun 16:2521850.  Abstract  
submitted by kickingbird at Jun, 17, 2025 from Emerg Microbes Infect. 2025 Jun 16:2521850 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
During the COVID-19 pandemic, stringent public health measures led to historically low influenza activity in Hong Kong. However, after these interventions were relaxed in 2023, Influenza A viruses (IAV), ...

Li H, Tong Q, Tao M, Li J, Yu H, Han Q, Wu J, Lan. Assessment of the public health risk of novel reassortant H3N3 avian influenza viruses that emerged in chickens. mBio. 2025 Jun 16:e0067725.  Abstract  
submitted by kickingbird at Jun, 17, 2025 from mBio. 2025 Jun 16:e0067725 (via https://journals.asm.org/doi/10.1128/mbio.00677-25)
Influenza A (H3N2) viruses are historically responsible for the 1968 Hong Kong flu pandemic. Since then, H3N2 has continued to circulate as a seasonal influenza virus in humans. Public health concerns ...

Esther Kissling, etc.,al. Influenza vaccine effectiveness in Europe and the birth cohort effect against influenza A(H1N1)pdm09: VEBIS primary care multicentre study, 2023/24. Eurosurveillance Volume 30, Issue 23.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from Eurosurveillance Volume 30, Issue 23 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
IntroductionInfluenza A(H1N1)pdm09, A(H3N2) and B/Victoria viruses circulated in Europe in 2023/24, with A(H1N1)pdm09 dominance. First influenza infections in childhood may lead to different vaccine effectiveness ...

Khakurel U, Sattenspiel L, Mamelund S-E. Role of Nonpharmaceutical Interventions during 1918~1920 Influenza Pandemic, Alaska, USA. Emerg Infect Dis. 2025 Jul.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from Emerg Infect Dis. 2025 Jul (via https://wwwnc.cdc.gov/eid/article/31/7/24-1048_article)
Previous studies investigating the 1918~1920 influenza pandemic have provided a comprehensive overview of the spread of the pandemic and possible explanations for high mortality rates in Alaska, USA. Our ...

Guinat C, Fourtune L, Lambert S, Martin E, Gerbier. Promising Effects of Duck Vaccination against Highly Pathogenic Avian Influenza, France 2023~2024. Emerg Infect Dis. 2025 Jul.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from Emerg Infect Dis. 2025 Jul (via https://wwwnc.cdc.gov/eid/article/31/7/24-1445_article)
Highly pathogenic avian influenza causes substantial poultry losses and zoonotic concerns globally. Duck vaccination against highly pathogenic avian influenza began in France in October 2023. Our assessment ...

Jones JE, Lakdawala SS. Host origin is a determinant of coevolution between gene segments of avian H9 influenza viruses. J Virol. 2025 Jun 13:e0151824.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from J Virol. 2025 Jun 13:e0151824 (via https://journals.asm.org/doi/10.1128/jvi.01518-24)
Several emerging influenza viruses, including H7N9 and H5N6 viruses, trace their origins to reassortment with H9N2 viruses that contributed internal gene segments. However, the evolutionary constraints ...

Lail AJ, Vuyk WC, Machkovech H, Minor NR, Hassan N. Amplicon sequencing of pasteurized retail dairy enables genomic surveillance of H5N1 avian influenza virus in United States cattle. PLoS One. 2025 Jun 13;20(6):e0325203.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from PLoS One. 2025 Jun 13;20(6):e0325203 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly pathogenic avian influenza (HPAI) viruses with H5 hemagglutinin (HA) genes (clade 2.3.4.4b) are causing an ongoing panzootic in wild birds. Circulation of these viruses is associated with spillover ...

Lai J, Bueno de Mesquita PJ, Hong F, Ma T, Cowling. Comparison of Viral Aerosol Shedding by Mild and Moderately Symptomatic Community-Acquired and Nasally Inoculated Influenza A(H3) Infection. Influenza Other Respir Viruses. 2025 Jun;19(6):e70.  Abstract  
submitted by kickingbird at Jun, 15, 2025 from Influenza Other Respir Viruses. 2025 Jun;19(6):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70129)
Background: Nasally inoculated influenza cases reported milder symptoms and shed lower viral RNA load in exhaled breath aerosols (EBA) than people with classic influenza-like illness in a previous study. ...

hi L, Lang Y, Roy S, Shen Z, Gupta D, Dai C, Khali. Outcomes of experimental infection of calves with swine influenza H3N2 virus. mBio 0:e03957-24.  Abstract  
submitted by kickingbird at Jun, 13, 2025 from mBio 0:e03957-24 (via https://journals.asm.org/doi/10.1128/mbio.03957-24)
Unprecedented outbreaks caused by the H5N1 highly pathogenic avian influenza virus (HPAIV) among dairy cows in the United States have raised significant concerns. Whether other subtypes of influenza A ...

Maria Ogrzewalska, etc.,al. [preprint]Genomic analysis of high pathogenicity avian influenza viruses from Antarctica reveals multiple introductions from South America. https://doi.org/10.21203/rs.3.rs-6727501/v1.  Abstract  
submitted by kickingbird at Jun, 13, 2025 from https://doi.org/10.21203/rs.3.rs-6727501/v1 (via https://www.researchsquare.com/article/rs-6727501/v1)
The spread of high pathogenicity avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b into Antarctica represents a major threat to polar wildlife. Here we report on the detection and genomic analysis of HPAIV ...

Jiang M, Zou J, Jin Y, Jiang C, Tu S, Chen T, Guo. Adducin-1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity. Adv Sci (Weinh). 2025 Jun 5:e2417318.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Adv Sci (Weinh). 2025 Jun 5:e2417318 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
Actin- and microtubule-based transport systems are essential for the trafficking of endocytic viruses and cargoes. Microtubules facilitate long-distance transport; however, the precise role of actin dynamics ...

Sullivan OM, Nesbitt DJ, Schaack GA, Feltman EM, N. IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency. J Virol. 2025 Jun 11:e0028625.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from J Virol. 2025 Jun 11:e0028625 (via https://journals.asm.org/doi/10.1128/jvi.00286-25)
Host cells produce a vast network of antiviral factors in response to viral infection. The interferon-induced proteins with tetratricopeptide repeats (IFITs) are important effectors of a broad-spectrum ...

Zhou W, Li X, Tian J, Liu S, Peng C, Li J, Hou G,. Development and application of a real-time fluorescent RAA assay for H9 subtype avian influenza viruses. Virus Genes. 2025 Jun 11.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Virus Genes. 2025 Jun 11 (via https://link.springer.com/article/10.1007/s11262-025-02167-x)
The H9N2 subtype of avian influenza virus (AIV) is a critical pathogen responsible for avian infectious diseases, inducing respiratory symptoms in poultry and exhibiting high susceptibility to coinfections, ...

Maria Alejandra Romero, etc.,al. Impact of the Avian Influenza Outbreak on the Population Dynamics of South American Sea Lions Otaria byronia in Northern Patagonia. Mar Mam Sci e70031.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Mar Mam Sci e70031 (via https://onlinelibrary.wiley.com/doi/10.1111/mms.70031)
Understanding the population dynamics of marine mammals is essential for assessing their resilience to historical harvesting pressures and current anthropogenic threats. The South American sea lion (SASL, ...

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