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2026-3-8 15:05:15
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Luo T, Liu L, Shen X, Irwin DM, Liao M, Shen Y. The evolutionary dynamics of H1N1/pdm2009 in India. Infect Genet Evol. 2018 Aug 14. pii: S1567-1348(18.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Infect Genet Evol. 2018 Aug 14. pii: S1567-1348(18 (via https://www.ncbi.nlm.nih.gov/pubmed/30118873)
After the 2009 pandemic H1N1 outbreak, this new reassortant virus replaced the previous seasonal H1N1 and established itself in human populations. In 2014-2015, the H1N1/pdm2009 pandemic strain caused ...

Heins MJ, Hooiveld M, Korevaar JC. Healthy elderly and influenza vaccination. Hum Vaccin Immunother. 2018 Aug 17:1-3.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Hum Vaccin Immunother. 2018 Aug 17:1-3 (via https://www.ncbi.nlm.nih.gov/pubmed/30118635)
In many countries, those at risk for complications due to influenza are invited for influenza vaccination, to prevent serious consequences for themselves and those around them. However, vaccination rates ...

Qian H, Zheng X. Ventilation control for airborne transmission of human exhaled bio-aerosols in buildings. J Thorac Dis. 2018 Jul;10(Suppl 19):S2295-S2304..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from J Thorac Dis. 2018 Jul;10(Suppl 19):S2295-S2304. (via https://www.ncbi.nlm.nih.gov/pubmed/30116608)
The emergence of respiratory diseases, i.e., severe acute respiratory syndrome (SARS) epidemic in 2003, H1N1 influenza epidemic in 2011 and Middle East respiratory syndrome (MERS) outbreak, reiterated ...

Norbert Pardi, etc.,al. Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies. Nature Communicationsvolume 9, Article number: 336.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Nature Communicationsvolume 9, Article number: 336 (via https://www.nature.com/articles/s41467-018-05482-0)
Currently available influenza virus vaccines have inadequate effectiveness and are reformulated annually due to viral antigenic drift. Thus, development of a vaccine that confers long-term protective immunity ...

Hermans D, Webby RJ, Wong SS. Atypical antibody responses to influenza. J Thorac Dis. 2018 Jul;10(Suppl 19):S2238-S2247..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from J Thorac Dis. 2018 Jul;10(Suppl 19):S2238-S2247. (via https://www.ncbi.nlm.nih.gov/pubmed/30116603)
Influenza viruses undergo rapid antigenic evolution and reassortment, resulting in annual epidemics and the occasional pandemics. Exposure to influenza virus hemagglutinin (HA) and neuraminidase (NA) antigen, ...

Akihiro Shibata, etc.,al. Repeated detection of H7N9 avian influenza viruses in raw poultry meat illegally brought to Japan by international flight passengers. Virology Nov 2018,Vol 524.  Abstract  
submitted by kickingbird at Aug, 22, 2018 from Virology Nov 2018,Vol 524 (via https://www.sciencedirect.com/science/article/pii/S004268221)
H7N9 highly and low pathogenic avian influenza viruses (HPAIV and LPAIV, respectively) have been isolated from duck meat products that were brought illegally into Japan by flight passengers in their hand ...

Eriksson P, etc.,al. Characterization of avian influenza virus attachment patterns to human and pig tissues. Sci Rep. 2018 Aug 15;8(1):12215..  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Sci Rep. 2018 Aug 15;8(1):12215. (via https://www.ncbi.nlm.nih.gov/pubmed/30111851)
Wild birds of Anseriformes and Charadriiformes are natural reservoirs of influenza A viruses (IAVs). Occasionally, IAVs transmit and adapt to mammalian hosts, and are maintained as epidemic strains in ...

Hancock AS, etc.,al. Transcriptome analysis of infected and bystander type 2 alveolar epithelial cells during influenza A virus infection reveals in vivo Wnt pathway downregulation. J Virol. 2018 Aug 15. pii: JVI.01325-18.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from J Virol. 2018 Aug 15. pii: JVI.01325-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30111569)
Influenza virus outbreaks remain a serious threat to public health. Greater understanding of how cells targeted by the virus respond to the infection can provide insight into the pathogenesis of disease. ...

Zhu W, etc.,al. Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch. Front Immunol. 2018 Jul 30;9:1705..  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1705. (via https://www.ncbi.nlm.nih.gov/pubmed/30105019)
Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed ...

Celestino I, etc.,al. Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice. Front Immunol. 2018 Jul 30;9:1747.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1747 (via https://www.ncbi.nlm.nih.gov/pubmed/30105026)
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple ...

Li X, Li C, Liu JC, Pan YP, Li YG. In vitro effect of Porphyromonas gingivalis combined with influenza A virus on respiratory epithelial cells. Arch Oral Biol. 2018 Apr 5;95:125-133.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Arch Oral Biol. 2018 Apr 5;95:125-133 (via https://www.ncbi.nlm.nih.gov/pubmed/30107300)
OBJECTIVE: Respiratory epithelial cells are the first natural barrier against bacteria and viruses; hence, the interactions among epithelial cells, bacteria, and viruses are associated with disease occurrence ...

Schechter-Perkins EM, etc.,al. Point-of-care influenza testing does not significantly shorten time to disposition among patients with an influenza-like illness. Am J Emerg Med. 2018 Aug 7.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Am J Emerg Med. 2018 Aug 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30107967)
INTRODUCTION: Availability of anti-viral agents and need to isolate infected patients increases the need to confirm the diagnosis of influenza before determining patient disposition.OBJECTIVES: We sought ...

Al-Ahdal MN, etc.,al. Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D. Front Immunol. 2018 Jul 30;9:1586.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1586 (via https://www.ncbi.nlm.nih.gov/pubmed/30105014)
Surfactant protein D (SP-D) is expressed in the mucosal secretion of the lung and contributes to the innate host defense against a variety of pathogens, including influenza A virus (IAV). SP-D can inhibit ...

Vette K, Bareja C, Clark R, Lal A. Establishing thresholds and parameters for pandemic influenza severity assessment, Australia. Bull World Health Organ. 2018 Aug 1;96(8):558-567.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Bull World Health Organ. 2018 Aug 1;96(8):558-567 (via https://www.ncbi.nlm.nih.gov/pubmed/30104796)
Objective: To implement the World Health Organization's pandemic influenza severity assessment tool in Australia, using multiple sources of data to establish thresholds and measure influenza severity indicators.Methods: ...

Lee JM, etc.,al. Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants. Proc Natl Acad Sci U S A. 2018 Aug 13.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Proc Natl Acad Sci U S A. 2018 Aug 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30104379)
Human influenza virus rapidly accumulates mutations in its major surface protein hemagglutinin (HA). The evolutionary success of influenza virus lineages depends on how these mutations affect HA's functionality ...

Wu Y, etc.,al. Prenatal influenza vaccination rescues impairments of social behavior and lamination in a mouse model of autism. J Neuroinflammation. 2018 Aug 13;15(1):228.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from J Neuroinflammation. 2018 Aug 13;15(1):228 (via https://www.ncbi.nlm.nih.gov/pubmed/30103815)
BACKGROUND: Prenatal infection is a substantial risk factor for neurodevelopmental disorders such as autism in offspring. We have previously reported that influenza vaccination (VAC) during early pregnancy ...

Mock DJ, etc.,al. Influenza Virus Infection of Human Lymphocytes Occurs in the Immune Cell Cluster of the Developing Antiviral Response. Viruses. 2018 Aug 10;10(8)..  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Viruses. 2018 Aug 10;10(8). (via https://www.ncbi.nlm.nih.gov/pubmed/30103427)
Monocytes-macrophages and lymphocytes are recruited to the respiratory tract in response to influenza virus challenge and are exposed to the virus during the establishment of immune defenses. The susceptibility ...

Zheng Z, Paul SS, Mo X, Yuan YA, Tan YJ. The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis. Vaccines (Basel). 2018 Aug 10;6(3)..  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Vaccines (Basel). 2018 Aug 10;6(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30103381)
Initial attempts to develop monoclonal antibodies as therapeutics to resolve influenza infections focused mainly on searching for antibodies with the potential to neutralise the virus in vitro with classical ...

Daniel Weibel, etc.,al. Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines – Multi-country assessment. Vaccine Available online 16 August 2018.  Abstract  
submitted by kickingbird at Aug, 18, 2018 from Vaccine Available online 16 August 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
AbstractBackgroundIn 2010, a safety signal was detected for narcolepsy following vaccination with Pandemrix, an AS03-adjuvanted monovalent pandemic H1N1 influenza (pH1N1) vaccine. To further assess a possible ...

Park JE, Ryu Y. Transmissibility and severity of influenza virus by subtype. Infect Genet Evol. 2018 Aug 10.  Abstract  
submitted by kickingbird at Aug, 16, 2018 from Infect Genet Evol. 2018 Aug 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30103034)
The characteristics of influenza might vary depending on the disease subtype. This review includes previous studies on the transmissibility and severity of influenza and summarizes them by subtype. The ...

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