Anchisi S, etc.,al. Influenza A Virus Genetic Tools: From Clinical Sample to Molecular Clone. Methods Mol Biol. 2018;1836:33-58. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:33-58 (via https://www.ncbi.nlm.nih.gov/pubmed/30151568)
Implementation of reverse genetics for influenza A virus, that is, the DNA-based generation of infectious viral particles in cell culture, opened new avenues to investigate the function of viral proteins ... Bruchhagen C, van Krüchten A, Klemm C, Ludwig S. In Vitro Models to Study Influenza Virus and Staphylococcus aureus Super-Infection on a Molecular Level. Methods Mol Biol. 2018;1836:375-386. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:375-386 (via https://www.ncbi.nlm.nih.gov/pubmed/30151583)
Investigation of pathogen-host interactions on a molecular level requires sophisticated in vitro infection procedures, especially in the presence of different pathogens.Super-infections of influenza viruses ... Creager HM, Tumpey TM, Maines TR, Belser JA. Infection of Cultured Mammalian Cells with Aerosolized Influenza Virus. Methods Mol Biol. 2018;1836:387-399.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:387-399. (via https://www.ncbi.nlm.nih.gov/pubmed/30151584)
Inoculation of animals via inhaled aerosols has long been used to study the infectivity and pathogenesis of both influenza virus and other respiratory pathogens in a context that mimics natural infection. ... Hemmink JD, Whittaker CJ, Shelton HA. Animal Models in Influenza Research. Methods Mol Biol. 2018;1836:401-430. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:401-430 (via https://www.ncbi.nlm.nih.gov/pubmed/30151585)
Animal model systems for human and animal influenza virus infection and transmission have been established to address research questions which cannot be addressed using in vitro models. Several animal ... Karlsson EA, etc.,al. Measuring Influenza Virus Infection Using Bioluminescent Reporter Viruses for In Vivo Imaging and In Vitro Replication Assays. Methods Mol Biol. 2018;1836:431-459. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:431-459 (via https://www.ncbi.nlm.nih.gov/pubmed/30151586)
To streamline standard virological assays, we developed bioluminescent replication-competent influenza reporter viruses that mimic their parental counterparts. These reporter viruses provide a rapid and ... Neumann G, Fan S, Kawaoka Y. Selection of Antigenically Advanced Variants of Influenza Viruses. Methods Mol Biol. 2018;1836:461-486. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:461-486 (via https://www.ncbi.nlm.nih.gov/pubmed/30151587)
Influenza virus epidemics are caused when seasonal influenza viruses (i.e., those circulating in humans) acquire mutations in the antigenic sites of the viral hemagglutinin (HA) protein that prevent the ... Liu WC, Nachbagauer R, Krammer F, Albrecht RA. Assessment of Influenza Virus Hemagglutinin Stalk-Specific Antibody Responses. Methods Mol Biol. 2018;1836:487-511. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:487-511 (via https://www.ncbi.nlm.nih.gov/pubmed/30151588)
Animal models are essential to examine the pathogenesis and transmission of influenza viruses and for preclinical evaluation of influenza virus vaccines. Among the animal models used in influenza virus ... DiPiazza AT, Richards KA, Liu WC, Albrecht RA. Analyses of Cellular Immune Responses in Ferrets Following Influenza Virus Infection. Methods Mol Biol. 2018;1836:513-530. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:513-530 (via https://www.ncbi.nlm.nih.gov/pubmed/30151589)
Ferrets are an ideal animal model in which to study the transmission of respiratory viruses as well as disease progression and vaccine efficacy because of their close anatomical and physiological resemblances ... Reimering S, McHardy AC. Software for Characterizing the Antigenic and Genetic Evolution of Human Influenza Viruses. Methods Mol Biol. 2018;1836:551-565. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:551-565 (via https://www.ncbi.nlm.nih.gov/pubmed/30151591)
Influenza viruses are rapidly evolving pathogens causing annual epidemics and occasional pandemics. The accumulation of amino acid substitutions allows the virus to adapt to changing environments like ... Finn A. Clinical Trials of Influenza Vaccines: Special Challenges. Methods Mol Biol. 2018;1836:567-573. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:567-573 (via https://www.ncbi.nlm.nih.gov/pubmed/30151592)
Clinical trials of vaccines differ from those of drugs both practically and ethically. Influenza vaccine trials pose additional challenges which flow from the seasonality of the disease and vaccine programmes ... Imperiale MJ, Howard D, Casadevall A. The Silver Lining in Gain-of-Function Experiments with Pathogens of Pandemic Potential. Methods Mol Biol. 2018;1836:575-587.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:575-587. (via https://www.ncbi.nlm.nih.gov/pubmed/30151593)
Half a decade after the contentious "gain-of-function" (GOF) debate of 2012 that followed experimentation showing that highly pathogenic avian influenza virus could become mammalian transmissible, it is ... Lipsitch M. Why Do Exceptionally Dangerous Gain-of-Function Experiments in Influenza?. Methods Mol Biol. 2018;1836:589-608. Abstract
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:589-608 (via https://www.ncbi.nlm.nih.gov/pubmed/30151594)
This chapter makes the case against performing exceptionally dangerous gain-of-function experiments that are designed to create potentially pandemic and novel strains of influenza, for example, by enhancing ... Yu J, etc.,al. Influenza-Associated Hospitalization in Children Younger Than Five Years of Age in Suzhou, China, 2011- 2016. Pediatr Infect Dis J. 2018 Aug 27.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Pediatr Infect Dis J. 2018 Aug 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30153228)
BACKGROUND: Studying the burden and risk factors associated with severe illness from influenza infection in young children in eastern China will contribute to future cost-effectiveness analyses of local ... Tian T, etc.,al. H3N2 influenza virus infection enhances Oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 Aug 21. Abstract
submitted by kickingbird at Aug, 31, 2018 from Exp Cell Res. 2018 Aug 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30142324)
Tight junctions (TJs) alteration is commonly seen in airway inflammatory diseases. Oncostatin M (OSM) is an inflammatory mediator associated with chronic rhinosinusitis with nasal polyps (CRSwNP). We have ... Belser JA, Maines TR, Tumpey TM. Importance of 1918 virus reconstruction to current assessments of pandemic risk. Virology. 2018 Aug 21;524:45-55. Abstract
submitted by kickingbird at Aug, 31, 2018 from Virology. 2018 Aug 21;524:45-55 (via https://www.ncbi.nlm.nih.gov/pubmed/30142572)
Reconstruction of the 1918 influenza virus has facilitated considerable advancements in our understanding of this extraordinary pandemic virus. However, the benefits of virus reconstruction are not limited ... D´Agostino I, etc.,al. Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction. Eur J Med Chem. 2018 Aug 13;157:743-758. Abstract
submitted by kickingbird at Aug, 31, 2018 from Eur J Med Chem. 2018 Aug 13;157:743-758 (via https://www.ncbi.nlm.nih.gov/pubmed/30142611)
The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant viruses make essential the development of new anti-flu ... Kronstad LM, Seiler C, Vergara R, Holmes SP. Differential Induction of IFN-α and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-γ Response to Influenza A Viruses. J Immunol. 2018 Aug 24. pii: ji1800161.. Abstract
submitted by kickingbird at Aug, 31, 2018 from J Immunol. 2018 Aug 24. pii: ji1800161. (via https://www.ncbi.nlm.nih.gov/pubmed/30143589)
In human and murine studies, IFN-γ is a critical mediator immunity to influenza. IFN-γ production is critical for viral clearance and the development of adaptive immune responses, yet excessive production ... Coletti P, Poletto C, Turbelin C, Blanchon T. Shifting patterns of seasonal influenza epidemics. Sci Rep. 2018 Aug 24;8(1):12786. Abstract
submitted by kickingbird at Aug, 31, 2018 from Sci Rep. 2018 Aug 24;8(1):12786 (via https://www.ncbi.nlm.nih.gov/pubmed/30143689)
Seasonal waves of influenza display a complex spatiotemporal pattern resulting from the interplay of biological, sociodemographic, and environmental factors. At country level many studies characterized ... Ermolenko EI, etc.,al. Anti-Influenza Activity of Enterocin B In vitro and Protective Effect of Bacteriocinogenic Enterococcal Probiotic Strain on Influenza Infection in Mouse Model. Probiotics Antimicrob Proteins. 2018 Aug 24.. Abstract
submitted by kickingbird at Aug, 31, 2018 from Probiotics Antimicrob Proteins. 2018 Aug 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30143997)
In spite of scientific evidence demonstrating the antiviral activity of lactic-acids bacteria, little is known about the mechanism of their action. Previously, several bacteriocins isolated from lactic ... Newall AT, Chen C, Wood JG, Stockwell MS. Within-season influenza vaccine waning suggests potential net benefits to delayed vaccination in older adults in the United States. Vaccine. 2018 Aug 23. pii: S0264-410X(18)31114-9. Abstract
submitted by kickingbird at Aug, 31, 2018 from Vaccine. 2018 Aug 23. pii: S0264-410X(18)31114-9 (via https://www.ncbi.nlm.nih.gov/pubmed/30146403)
BACKGROUND: There is growing evidence that there is within (intra-) season waning of influenza vaccine protection in older adults, suggesting there may be a benefit to giving influenza vaccine closer to ... 9879 items, 20/Page, Page[317/494][|<<] [|<] [311] [312] [313] [314] [315] [316] [317] [318] [319] [320] [>|] [>>|] |
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