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2026-3-8 16:44:37
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Yamayoshi S, Yasuhara A, Ito M, Uraki R, Kawaoka Y. Differences in the ease with which mutant viruses escape from human monoclonal antibodies against the HA stem of influenza A virus. J Clin Virol. 2018 Sep 26;108:105-111.  Abstract  
submitted by kickingbird at Oct, 11, 2018 from J Clin Virol. 2018 Sep 26;108:105-111 (via https://www.ncbi.nlm.nih.gov/pubmed/30292135)
BACKGROUND: Broadly protective human monoclonal antibodies that recognize the conserved epitopes in the HA of influenza A virus are being developed as therapeutic agents. Emergence of resistant viruses ...

Marchenko V, etc.,al. Isolation and characterization of H5Nx highly pathogenic avian influenza viruses of clade 2.3.4.4 in Russia. Virology. 2018 Oct 5;525:216-223.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Virology. 2018 Oct 5;525:216-223 (via https://www.ncbi.nlm.nih.gov/pubmed/30296682)
In 2016-2017, several subtypes of the highly pathogenic avian influenza (HPAI) virus were isolated on the territory of Russia. In the autumn of 2016, during the avian influenza virus surveillance in the ...

Rodriguez-Lainz A, et.,al. Influenza vaccination coverage among US-Mexico land border crossers: 2009 H1N1 pandemic and 2011-2012 influenza season. Travel Med Infect Dis. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Travel Med Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30296482)
BACKGROUND: The high volume of US-Mexico land border crossings can facilitate international dissemination of influenza viruses.METHODS: We surveyed adult pedestrians crossing into the United States at ...

Hill AT, et.,al. Adult Outpatients with Acute Cough due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report. Chest. 2018 Oct 5.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Chest. 2018 Oct 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30296418)
BACKGROUND: Patients commonly present to primary care services with upper and lower respiratory tract infections and guidelines to help clinicians investigate and treat acute cough due to suspected pneumonia ...

Poon CM, Yi Wong EL, Chau PYK, Yau SY, Yeoh EK. Management decision of hospital surge: assessing seasonal upsurge in inpatient medical bed occupancy rate among public acute hospitals in Hong Kong.. QJM. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 10, 2018 from QJM. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30295857)
Background: There were recurrent upsurges in demand for public hospital services in Hong Kong. An understanding of the contribution of some possible factors for the rise in health care burden would help ...

Haag R, et., al. Exploring rigid and flexible core trivalent sialosides for influenza virus inhibition. Chemistry. 2018 Oct 8..  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Chemistry. 2018 Oct 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30295350)
We describe the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers interacting with spike proteins of influenza ...

Kyaw WM, Chow A, Hein AA, Lee LT, Leo YS, Ho HJ. Factors influencing seasonal influenza vaccination uptake among health care workers in an adult tertiary care hospital in Singapore: A cross-sectional survey. Am J Infect Control. 2018 Oct 4.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Am J Infect Control. 2018 Oct 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30293741)
BACKGROUND: This study aimed to evaluate the factors influencing seasonal influenza vaccination uptake among different health care professional groups.METHODS: A single-center, cross-sectional survey using ...

Hayden FG. et al. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 Sep 6;379(10):913-923.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from N Engl J Med. 2018 Sep 6;379(10):913-923 (via https://www.nejm.org/doi/full/10.1056/NEJMoa1716197)
BackgroundBaloxavir marboxil is a selective inhibitor of influenza cap-dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains ...

Steve G.Robison, Ann R.Thomas. Assessing the effectiveness of high-dose influenza vaccine in preventing hospitalization among seniors, and observations on the limitations of effectiveness study design. Vaccine 1 October 2018.  Abstract  
submitted by kickingbird at Oct, 9, 2018 from Vaccine 1 October 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BackgroundThe availability of high-dose (HD) influenza vaccine for seniors should decrease influenza-related hospitalization. Studies to date show a range of mostly moderate increased HD vaccine effectiveness ...

Chang P, Sealy JE, Sadeyen JR, Iqbal M. Amino acid residue 217 in the hemagglutinin glycoprotein is a key mediator of avian influenza H7N9 virus antigenicity. J Virol. 2018 Oct 3. pii: JVI.01627-18.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3. pii: JVI.01627-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30282714)
Avian influenza viruses continue to evolve and acquire mutations that facilitate antigenic drift and virulence change. In 2017, low pathogenicity H7N9 avian influenza viruses evolved to a high pathogenicity ...

Wang S, etc.,al. Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function. Vet Res. 2018 Oct 1;49(1):98.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Vet Res. 2018 Oct 1;49(1):98 (via https://www.ncbi.nlm.nih.gov/pubmed/30285871)
The emerging avian-origin H7N9 influenza A virus, which causes mild to lethal human respiratory disease, continues to circulate in China, posing a great threat to public health. Influenza NS1 protein plays ...

Young B, etc.,al. Six-monthly versus annual influenza vaccination in older adults in the tropics: an observer-blind, active-comparator controlled, randomised superiority trial. Clin Infect Dis. 2018 Oct 1..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Clin Infect Dis. 2018 Oct 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30277500)
Background: Antibody titres and vaccine effectiveness decline within six months after influenza vaccination in older adults. Biannual vaccination may be necessary to provide year-round protection in the ...

Shanks GD. The ´Influenza´ Vaccine Used during the Samoan Pandemic of 1918. Trop Med Infect Dis. 2018 Feb 2;3(1).  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Trop Med Infect Dis. 2018 Feb 2;3(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30274415)
In 1918, a crude influenza vaccine made from chemically inactivated, mixed cultures of respiratory bacteria was widely used prior to the understanding that influenza was caused by a virus. Such vaccines ...

Hayashi T, etc.,al. Impact of early life exposure to ionizing radiation on influenza vaccine response in an elderly Japanese cohort. Vaccine. 2018 Sep 28.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Vaccine. 2018 Sep 28 (via https://www.ncbi.nlm.nih.gov/pubmed/30274868)
The objective of this study was to evaluate effects of whole body radiation exposure early in life on influenza vaccination immune responses much later in life. A total of 292 volunteers recruited from ...

Mirzaei SG, Shoushtari A, Nouri A. Development and Evaluation of Real-Time RT-PCR Test for Quantitative and Qualitative Recognition of Current H9N2 Subtype Avian Influenza Viruses in Iran. Arch Razi Inst. 2018 Sep;73(3):177-182.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Arch Razi Inst. 2018 Sep;73(3):177-182 (via https://www.ncbi.nlm.nih.gov/pubmed/30280837)
Avian influenza H9N2 subtype viruses have had a great impact on Iranian industrial poultry production economy since introduction in the country. To approach Rapid and precise identification of this viruses ...

Hatayama K, etc.,al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2018 Oct 3.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Med Virol. 2018 Oct 3 (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury (ALI) due to excessive inflammatory reaction, even with neuraminidase inhibitor use. The ...

Okamoto M, etc.,al. MicroRNA-451a in extracellular, blood-resident vesicles attenuates macrophage and dendritic cell responses to influenza whole-virus vaccine. J Biol Chem. 2018 Oct 3..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Biol Chem. 2018 Oct 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30282637)
The innate immune system is important for the efficacy of vaccines, but excessive innate immune responses can cause adverse reactions after vaccination. Extracellular vesicles (EVs) are enriched in the ...

Fay EJ, etc.,al. Engineered small molecule control of influenza A virus replication. J Virol. 2018 Oct 3..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30282710)
Influenza A virus (IAV) remains a global health concern despite the availability of a seasonal vaccine. It is difficult to predict which strains will circulate during influenza season, and therefore extremely ...

Jang Y, etc.,al. Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 Function. J Virol. 2018 Oct 3.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3 (via https://www.ncbi.nlm.nih.gov/pubmed/30282713)
Screening of chemical libraries with 2,000 synthetic compounds identified salinomycin as a hit against influenza A and B viruses with 50% effective concentrations ranging from 0.4 to 4.3 μM in cells. This ...

Lee JJ, etc.,al. The clinical utility of point-of-care tests for influenza in ambulatory care: A systematic review and meta-analysis. Clin Infect Dis. 2018 Oct 4..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Clin Infect Dis. 2018 Oct 4. (via https://www.ncbi.nlm.nih.gov/pubmed/30285232)
Background: Point-of-care tests (POCTs) for influenza are diagnostically superior to clinical diagnosis, but their impact on patient outcomes is unclear.Methods: A systematic review of influenza POCTs ...

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