Barrat-Charlaix P, Vaughan TG, Neher RA. TreeKnit: Inferring ancestral reassortment graphs of influenza viruses. PLoS Comput Biol. 2022 Aug 19;18(8):e1010394. Abstract
submitted by kickingbird at Aug, 23, 2022 from PLoS Comput Biol. 2022 Aug 19;18(8):e1010394 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source of genetic diversity and is known to have been ... Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mou. DDX58 is Associated with Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 Aug 20:jiac350. Abstract
submitted by kickingbird at Aug, 23, 2022 from J Infect Dis. 2022 Aug 20:jiac350 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Seasonal influenza virus infection causes a range of disease severity, including lower respiratory tract infection with respiratory failure. We evaluated the association of common variants ... Miao X, Feng M, Zhu O, Yang F, Yin Y, Yin Y, Chen. H5N8 Subtype Avian Influenza Virus Isolated from Migratory Birds Emerging in Eastern China Possessed a High Pathogenicity in Mammals. Transbound Emerg Dis. 2022 Aug 21. Abstract
submitted by kickingbird at Aug, 23, 2022 from Transbound Emerg Dis. 2022 Aug 21 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14685)
Novel H5N8 highly pathogenic avian influenza viruses (HPAIVs) bearing the clade 2.3.4.4b HA gene have been widely spread through wild migratory birds since 2020. One H5N8 HPAIV (A/Wild bird/Cixi/Cixi02/2020; ... Jakob C, Paul-Stansilaus R, Schwemmle M, Marquet R. The influenza A virus genome packaging network - complex, flexible and yet unsolved. Nucleic Acids Res. 2022 Aug 22:gkac688. Abstract
submitted by kickingbird at Aug, 23, 2022 from Nucleic Acids Res. 2022 Aug 22:gkac688 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
The genome of influenza A virus (IAV) consists of eight unique viral RNA segments. This genome organization allows genetic reassortment between co-infecting IAV strains, whereby new IAVs with altered genome ... Blaurock C, Pfaff F, Scheibner D, Hoffmann B, Fusa. Evidence for Different Virulence Determinants and Host Response after Infection of Turkeys and Chickens with Highly Pathogenic H7N1 Avian Influenza Virus. J Virol. 2022 Aug 22:e0099422. Abstract
submitted by kickingbird at Aug, 23, 2022 from J Virol. 2022 Aug 22:e0099422 (via https://journals.asm.org/doi/10.1128/jvi.00994-22)
Wild birds are the reservoir for all avian influenza viruses (AIV). In poultry, the transition from low pathogenic (LP) AIV of H5 and H7 subtypes to highly pathogenic (HP) AIV is accompanied mainly by ... Cui M, Huang Y, Wang X, Bian X, Du L, Yan Y, Gu J,. Genetic characterization and evolution of H6N6 subtype avian influenza viruses. Front Microbiol. 2022 Aug 1;13:963218. Abstract
submitted by kickingbird at Aug, 19, 2022 from Front Microbiol. 2022 Aug 1;13:963218 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9632)
H6-subtype avian influenza virus (AIV) was prevalent in the world and could sporadically infect humans. Here, a new chicken-derived H6N6-subtype AIV strain A/chicken/Zhejiang/49/2021 (ZJ49) was isolated ... He D, Gu M, Hao X, Zhan T, Wang X, Wang X, Hu S, L. A dominant internal gene cassette of high pathogenicity avian influenza H7N9 virus raised since 2018. Virus Genes. 2022 Aug 16. Abstract
submitted by kickingbird at Aug, 17, 2022 from Virus Genes. 2022 Aug 16 (via https://link.springer.com/article/10.1007/s11262-022-01928-2)
The zoonotic H7N9 avian influenza virus emerged with the H9N2-origin internal gene cassette. Previous studies have reported that genetic reassortments with H9N2 were common in the first five human H7N9 ... Meng F, Yang H, Qu Z, Chen Y, Zhang Y, Zhang Y, Li. A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e220. Abstract
submitted by kickingbird at Aug, 16, 2022 from Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e220 (via https://www.pnas.org/doi/abs/10.1073/pnas.2203919119)
Previous studies have shown that the Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses circulated widely in pigs around the world and formed multiple genotypes by acquiring non-hemagglutinin and ... Rimondi A, Olivera VS, Soria I, Parisi GD, Rumbo M. Few Amino Acid Mutations in H6 Influenza A Virus From South American Lineage Increase Viral Replication Efficiency in Poultry. Front Microbiol. 2022 Jul 27;13:953738. Abstract
submitted by kickingbird at Aug, 16, 2022 from Front Microbiol. 2022 Jul 27;13:953738 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9537)
In chickens, infections due to influenza A virus (IAV) can be mild to severe and lethal. The study of IAV infections in poultry has been mostly limited to strains from the North American and Eurasian lineages, ... Strohmeier S, Amanat F, Carre?o JM, Krammer F. Monoclonal antibodies targeting the influenza virus N6 neuraminidase. Front Immunol. 2022 Jul 27;13:944907. Abstract
submitted by kickingbird at Aug, 16, 2022 from Front Immunol. 2022 Jul 27;13:944907 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.9449)
Influenza A viruses are a diverse species that include 16 true hemagglutinin (HA) subtypes and 9 true neuraminidase (NA) subtypes. While the antigenicity of many HA subtypes is reasonably well studied, ... Zhang Y, Eskridge KM, Zhang S, Lu G. Identifying host-specific amino acid signatures for influenza A viruses using an adjusted entropy measure. BMC Bioinformatics. 2022 Aug 12;23(1):333. Abstract
submitted by kickingbird at Aug, 14, 2022 from BMC Bioinformatics. 2022 Aug 12;23(1):333 (via https://bmcbioinformatics.biomedcentral.com/articles/10.1186)
Background: Influenza A viruses (IAV) exhibit vast genetic mutability and have great zoonotic potential to infect avian and mammalian hosts and are known to be responsible for a number of pandemics. A ... Dai M, Sun H, Zhao L, Wu Q, You B, Xu F, Liao J, Z. Duck CD8 + T Cell Response to H5N1 Highly Pathogenic Avian Influenza Virus Infection In Vivo and In Vitro. J Immunol. 2022 Aug 8:ji2101147. Abstract
submitted by kickingbird at Aug, 10, 2022 from J Immunol. 2022 Aug 8:ji2101147 (via https://pubmed.ncbi.nlm.nih.gov/35940633/)
Domestic ducks are the important host for H5N1 highly pathogenic avian influenza virus (HPAIV) infection and epidemiology, but little is known about the duck T cell response to H5N1 AIV infection. In infection ... Cheng HY, Fung E, Choi KC, Zou HJ, Chair SY. Early risk of acute myocardial infarction following hospitalization for severe influenza infection in the middle-aged population of Hong Kong. PLoS One. 2022 Aug 9;17(8):e0272661. Abstract
submitted by kickingbird at Aug, 10, 2022 from PLoS One. 2022 Aug 9;17(8):e0272661 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Introduction: Despite evidence suggesting an association between influenza infection and increased risk of acute myocardial infarction (AMI) in the older adult population (aged 65 years or above), little ... Azeem S, Guo B, Sun D, Killian ML, Baroch JA, Yoon. Evaluation of PCR-Based Hemagglutinin Subtyping as a Tool to aid in Surveillance of Avian Influenza viruses in Migratory Wild Birds. J Virol Methods. 2022 Aug 2:114594. Abstract
submitted by kickingbird at Aug, 7, 2022 from J Virol Methods. 2022 Aug 2:114594 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
The surveillance of migratory wild birds (MWBs) for avian influenza virus (AIV) allows detecting the emergence of highly pathogenic AIV that can infect domestic poultry and mammals, new subtypes, and antigenic/genetic ... Wang T, Wei F, Jiang Z, Song J, Li C, Liu J. Influenza virus NS1 interacts with 14-3-3ε to antagonize the production of RIG-I-mediated type I interferons. Virology. 2022 Jul 20;574:47-56. Abstract
submitted by kickingbird at Aug, 6, 2022 from Virology. 2022 Jul 20;574:47-56 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
For influenza A viruses (IAVs), non-structural protein 1 (NS1) protein was recognized to be the key factor to enhance virulence by antagonizing host innate anti-viral responses. However, for the pathways ... He J, Huang H, Li B, Li H, Zhao Y, Li Y, Ye W, Qi. Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication. Front Microbiol. 2022 Jul 19;13:862205. Abstract
submitted by kickingbird at Aug, 6, 2022 from Front Microbiol. 2022 Jul 19;13:862205 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8622)
Human infection with highly pathogenic H5N1 influenza virus causes severe respiratory diseases. Currently, the drugs against H5N1 are limited to virus-targeted inhibitors. However, drug resistance caused ... Mao H, Cao L, Xu T, Xia X, Ren P, Han P, Li C, Hui. YWHAG inhibits influenza a virus replication by suppressing the release of viral M2 protein. Front Microbiol. 2022 Jul 19;13:951009. Abstract
submitted by kickingbird at Aug, 6, 2022 from Front Microbiol. 2022 Jul 19;13:951009 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9510)
Influenza A virus (IAV) poses a serious threat to human life and property. The IAV matrix protein 2 (M2) is significant in viral budding. Increasing studies have proven the important roles of host factors ... Oh J, Subbiah J, Kim KH, Park BR, Bhatnagar N, Gar. Impact of hemagglutination activity and M2e immunity on conferring protection against influenza viruses. Virology. 2022 Jul 16;574:37-46. Abstract
submitted by kickingbird at Aug, 5, 2022 from Virology. 2022 Jul 16;574:37-46 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
To improve cross-protection of influenza vaccination, we tested conjugation of conserved M2e epitopes to the surface of inactivated influenza virus (iPR8-M2e*). Treatment of virus with chemical cross-linker ... Chan M, Tiwary M, Wu HL, Tailor N, Vendramelli R,. Pandemic 1918 Influenza Virus Does Not Cause Lethal Infection in Rhesus or Cynomolgus Macaques. J Virol. 2022 Aug 4:e0072822. Abstract
submitted by kickingbird at Aug, 5, 2022 from J Virol. 2022 Aug 4:e0072822 (via https://journals.asm.org/doi/10.1128/jvi.00728-22)
The 1918 H1N1 influenza pandemic was among the most severe in history, taking the lives of approximately 50 million people worldwide, and novel prophylactic vaccines are urgently needed to prevent another ... Zhao X, Lin X, Li P, Chen Z, Zhang C, Manicassamy. Expanding the tolerance of segmented Influenza A Virus genome using a balance compensation strategy. PLoS Pathog. 2022 Aug 4;18(8):e1010756. Abstract
submitted by kickingbird at Aug, 5, 2022 from PLoS Pathog. 2022 Aug 4;18(8):e1010756 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Reporter viruses provide powerful tools for both basic and applied virology studies, however, the creation and exploitation of reporter influenza A viruses (IAVs) have been hindered by the limited tolerance ... 6469 items, 20/Page, Page[98/324][|<<] [|<] [91] [92] [93] [94] [95] [96] [97] [98] [99] [100] [>|] [>>|] |
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