Xia M, Huang P, Vago FS, Jiang W, Tan M. Pseudovirus nanoparticles targeting the receptor binding HA1 domains of influenza viruses elicited high HA1-specific antibody responses and protected mice against mortality caused by influenza virus c. Vaccine. 2024 Dec 7:126585. Abstract
submitted by kickingbird at Dec, 9, 2024 from Vaccine. 2024 Dec 7:126585 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The continually high disease burden of influenza and the relatively low effectiveness of current influenza vaccines call for enhanced vaccine strategies. We previously generated unique S-HA1 pseudovirus ... Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilb. Marked Neurotropism and Potential Adaptation of H5N1 Clade 2.3.4.4.b Virus in Naturally Infected Domestic Cats. Emerg Microbes Infect. 2024 Dec 9:2440498. Abstract
submitted by kickingbird at Dec, 9, 2024 from Emerg Microbes Infect. 2024 Dec 9:2440498 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. ... Gunasekara E, Hair-Bejo M, Aini I, Omar AR. Molecular characterisation of novel reassortants of the G57 genotype of low-pathogenic avian influenza H9N2 virus isolated from poultry farms in Malaysia. Arch Virol. 2024 Dec 7;170(1):3. Abstract
submitted by kickingbird at Dec, 8, 2024 from Arch Virol. 2024 Dec 7;170(1):3 (via https://link.springer.com/article/10.1007/s00705-024-06159-4)
In late 2017, Malaysia reported repeated outbreaks of low-pathogenic avian influenza virus (LPAI) H9N2 infections in commercial poultry flocks. Two H9N2 viruses, A/chicken/Malaysia/Negeri Sembilan/UPM994/2018 ... Isabela Carvalho Brcko, etc.,al. Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis. Virus Evolution, veae102. Abstract
submitted by kickingbird at Dec, 7, 2024 from Virus Evolution, veae102 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Influenza A and B viruses represent significant global health threats, contributing substantially to morbidity and mortality rates. However, a comprehensive understanding of the molecular epidemiology ... Jiawei Luo, etc.,al. The PB1 protein of H9N2 influenza A virus inhibits antiviral innate immunity by targeting MAVS for TRIM25-mediated autophagic degradation. Poultry Science. Abstract
submitted by kickingbird at Dec, 7, 2024 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. However, the regulatory mechanisms remain not fully understood. ... Nuo Xu, etc.,al. The evolution of hemagglutinin-158 and neuraminidase-88 glycosylation sites modulates antigenicity and pathogenicity of clade 2.3.2.1 H5N1 avian influenza viruses. Veterinary Microbiology. Abstract
submitted by kickingbird at Dec, 7, 2024 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Clade 2.3.2.1 of the H5N1 avian influenza virus (AIV) evolved into several subclades. However, the effect of glycosylation on the biological characteristics of hemagglutinin (HA) and/or neuraminidase (NA) ... Matthew L Turnbull, etc.,al. [preprint]POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS. https://doi.org/10.1101/2024.11.29.626120. Abstract
submitted by kickingbird at Dec, 6, 2024 from https://doi.org/10.1101/2024.11.29.626120 (via https://www.biorxiv.org/content/10.1101/2024.11.29.626120v1)
H5N1 avian influenza virus (lineage 2.3.4.4b, B3.13 genotype) has caused, unexpectedly, a large outbreak in dairy cattle in North America. It is critical to ascertain how this virus has specifically adapted ... Lv H, Teo QW, Lee C-CD, Liang W, Choi D, Mao KJ, A. Differential antigenic imprinting effects between influenza H1N1 hemagglutinin and neuraminidase in a mouse model. J Virol. 2024 Dec 5:e0169524. Abstract
submitted by kickingbird at Dec, 6, 2024 from J Virol. 2024 Dec 5:e0169524 (via https://journals.asm.org/doi/10.1128/jvi.01695-24)
Understanding how immune history influences influenza immunity is essential for developing effective vaccines and therapeutic strategies. This study examines the antigenic imprinting of influenza hemagglutinin ... Lin TH, Zhu X, Wang S, Zhang D, McBride R, Yu W, B. A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors. Science. 2024 Dec 6;386(6726):1128-1134. Abstract
submitted by kickingbird at Dec, 6, 2024 from Science. 2024 Dec 6;386(6726):1128-1134 (via https://www.science.org/doi/10.1126/science.adt0180)
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-human ... Yang K, Nizami S, Hu S, Zou L, Deng H, Xie J, Guo. Genetic diversity of highly pathogenic avian influenza H5N6 and H5N8 viruses in poultry markets in Guangdong, China, 2020~2022. J Virol. 2024 Dec 4:e0114524. Abstract
submitted by kickingbird at Dec, 5, 2024 from J Virol. 2024 Dec 4:e0114524 (via https://journals.asm.org/doi/10.1128/jvi.01145-24)
H5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and wild birds, with sporadic spillover infections ... Tosheva II, Filaire F, Rijnink WF, de Meulder D, v. Influenza A(H5N1) shedding in air corresponds to transmissibility in mammals. Nat Microbiol. 2024 Dec 2. Abstract
submitted by kickingbird at Dec, 4, 2024 from Nat Microbiol. 2024 Dec 2 (via https://www.nature.com/articles/s41564-024-01885-6)
An increase in spillover events of highly pathogenic avian influenza A(H5N1) viruses to mammals suggests selection of viruses that transmit well in mammals. Here we use air-sampling devices to continuously ... Guilfoyle K, Mirolo M, van Amerongen G, van der Ne. Susceptibility of calf lung slice cultures to H5N1 influenza virus. Emerg Microbes Infect. 2024 Dec 3:2432368. Abstract
submitted by kickingbird at Dec, 4, 2024 from Emerg Microbes Infect. 2024 Dec 3:2432368 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging ... Deng Y-M, Wille M, Dapat C, Xie R, Lay O, Peck H,. Influenza A(H5N1) Virus Clade 2.3.2.1a in Traveler Returning to Australia from India, 2024. Emerg Infect Dis. 2025 Jan. Abstract
submitted by kickingbird at Dec, 4, 2024 from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1210_article)
We report highly pathogenic avian influenza A(H5N1) virus clade 2.3.2.1a in a child traveler returning to Australia from India. The virus was a previously unreported reassortant consisting of clade 2.3.2.1a, ... Li L, Xu J, Yuan J, Zhang R, Xu T. TRPM2 deficiency ameliorated H9N2 influenza virus-induced acute lung injury in mice. Microb Pathog. 2024 Nov 28:107183. Abstract
submitted by kickingbird at Dec, 2, 2024 from Microb Pathog. 2024 Nov 28:107183 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Oxidative stress is involved in lung damage induced by the influenza virus. The transient receptor potential melastatin-2 (TRPM2) cation channel, a Ca2+ permeable non-selective cation channel, is implicated ... Lisa Bauer, etc.,al. [preprint]A 2022 avian H5N1 influenza A virus from clade 2.3.4.4b attaches to and replicates better in human respiratory epithelium than a 2005 H5N1 virus from clade 2.3.2.1. https://doi.org/10.1101/2024.11.27.625596. Abstract
submitted by kickingbird at Nov, 29, 2024 from https://doi.org/10.1101/2024.11.27.625596 (via https://www.biorxiv.org/content/10.1101/2024.11.27.625596v1)
Background: Highly pathogenic avian influenza (HPAI) H5 viruses of the A/Goose/Guangdong/1/1996 (GsGd) lineage pose significant global risks to wildlife, domestic animals, and humans. Recent cross-species ... Storms SM, Leonardi-Cattolica A, Prezioso T, Varga. Influenza A virus shedding and reinfection during the post-weaning period in swine: longitudinal study of two nurseries. Front Vet Sci. 2024 Nov 13;11:1482225. Abstract
submitted by kickingbird at Nov, 29, 2024 from Front Vet Sci. 2024 Nov 13;11:1482225 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Introduction: Influenza A virus in swine (IAV-S) is common in the United States commercial swine population and has the potential for zoonotic transmission.Objective: To elucidate influenza shedding the ... Feoktistova SG, Ivanova AO, Degtyarev EP, Smirnova. Phylogenetic Insights into H7Nx Influenza Viruses: Uncovering Reassortment Patterns and Geographic Variability. Viruses. 2024 Oct 23;16(11):1656. Abstract
submitted by kickingbird at Nov, 28, 2024 from Viruses. 2024 Oct 23;16(11):1656 (via https://www.mdpi.com/1999-4915/16/11/1656)
Influenza A viruses (IAVs), which belong to the Orthomyxoviridae family, are RNA viruses characterized by a segmented genome that allows them to evolve and adapt rapidly. These viruses are mainly transmitted ... Stallknecht DE, Carter DL, Sullivan-Brügger L, Lin. Highly Pathogenic H5N1 Influenza A Virus (IAV) in Blue-Winged Teal in the Mississippi Flyway Is Following the Historic Seasonal Pattern of Low-Pathogenicity IAV in Ducks. Pathogens. 2024 Nov 19;13(11):1017. Abstract
submitted by kickingbird at Nov, 28, 2024 from Pathogens. 2024 Nov 19;13(11):1017 (via https://www.mdpi.com/2076-0817/13/11/1017)
Highly pathogenic H5N1 (HP H5N1) influenza A virus (IAV) has been detected annually in North American ducks since its introduction during 2021, but it is unknown if this virus will follow the same seasonal ... Zhu W, Yang L, Han X, Tan M, Zou S, Li X, Huang W,. Origin, pathogenicity, and transmissibility of a human isolated influenza A(H10N3) virus from China. Emerg Microbes Infect. 2024 Nov 27:2432364. Abstract
submitted by kickingbird at Nov, 28, 2024 from Emerg Microbes Infect. 2024 Nov 27:2432364 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Subtype H10 viruses are known to infect humans in Africa, Oceania, and Asia. In 2021, 2022, and recently in April 2024, a novel H10N3 subtype avian influenza virus was found that caused human infection ... Wight J, Rahman I, Wallace HL, Cunningham JT, Roul. Avian influenza virus circulation and immunity in a wild urban duck population prior to and during a highly pathogenic H5N1 outbreak. Vet Res. 2024 Nov 22;55(1):154. Abstract
submitted by kickingbird at Nov, 27, 2024 from Vet Res. 2024 Nov 22;55(1):154 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses were first detected in St. John's, Canada in late 2021. To investigate the patterns of avian influenza virus (AIV) infection and immune ... 7184 items, 20/Page, Page[80/360][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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