Wang J, Zhang Y, Sun L, Wang Z, Hao C, Wang W. Eukaryotic RNA Binding Protein hnRNPH1 Suppresses Influenza A Virus Replication through Interaction with Virus NS1 Protein. Emerg Microbes Infect. 2025 Mar 7:2477645. Abstract
submitted by kickingbird at Mar, 10, 2025 from Emerg Microbes Infect. 2025 Mar 7:2477645 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The NS1 protein of influenza A virus (IAV) is a multi-functional protein which can antagonize host immune system and facilitate viral replication by interacting with host factors. However, the novel partners ... Li, X., Li, L., Tian, J., Su, R., Sun, J., Li, Y.,. SREBP2-dependent lipid droplet formation enhances viral replication and deteriorates lung injury in mice following IAV infection. Emerging Microbes & Infections, 14(1). Abstract
submitted by kickingbird at Mar, 10, 2025 from Emerging Microbes & Infections, 14(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A virus (IAV) is a significant zoonotic pathogen that poses a considerable challenge to public health due to its continuous mutations. Lipid droplets (LDs) have been shown to play an important ... Pascua PNQ, Chesnokov A, Nguyen HT, Di H, Cruz JDL. Antiviral Susceptibility of Influenza A(H5N1) Clade 2.3.2.1c and 2.3.4.4b Viruses from Humans, 2023~2024. Emerg Infect Dis. 2025 Apr. Abstract
submitted by kickingbird at Mar, 9, 2025 from Emerg Infect Dis. 2025 Apr (via https://wwwnc.cdc.gov/eid/article/31/4/24-1820_article)
During 2023~2024, highly pathogenic avian influenza A(H5N1) viruses from clade 2.3.2.1c caused human infections in Cambodia and from clade 2.3.4.4b caused human infections in the Americas. We assessed ... Levine MZ, Liu F, Bagdasarian N, Haliday C, Jeffer. Neutralizing Antibody Response to Influenza A(H5N1) Virus in Dairy Farm Workers, Michigan, USA. Emerg Infect Dis. 2025 Apr. Abstract
submitted by kickingbird at Mar, 9, 2025 from Emerg Infect Dis. 2025 Apr (via https://wwwnc.cdc.gov/eid/article/31/4/25-0007_article)
Since March 2024, highly pathogenic avian influenza A(H5N1) viruses have caused outbreaks in dairy cattle and poultry in the United States, and they continue to spill over into humans. However, data on ... Xiao N, Oong XY, Chen Y, Li C, Chung HC, Wang P, Y. Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice. Emerg Microbes Infect. 2025 Mar 4:2475836. Abstract
submitted by kickingbird at Mar, 8, 2025 from Emerg Microbes Infect. 2025 Mar 4:2475836 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The newly emerged avian influenza A H5N1 Clade 2.3.4.4b can infect dairy cows and shed live virus in their milk. Sporadic cattle-to-human infections have been reported, highlighting the urgent need to ... Lu X, Li W, Li P, Li Y, Gou Y, Wang T, Liu Z, Wu Y. Selection and identification of an ssDNA aptamer against influenza B virus hemagglutinin protein. Virol J. 2025 Mar 7;22(1):64. Abstract
submitted by kickingbird at Mar, 8, 2025 from Virol J. 2025 Mar 7;22(1):64 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The influenza virus causes infectious respiratory disease with high morbidity and mortality worldwide. Influenza B typically goes unnoticed owing to its mild clinical symptoms and limitations. ... Jing Yang, etc.,al. A human-infecting H10N5 avian influenza virus: clinical features, virus reassortment, receptor-binding affinity, and possible transmission routes. Journal of Infection Available online 4 March 2025. Abstract
submitted by kickingbird at Mar, 6, 2025 from Journal of Infection Available online 4 March 2025 (via https://www.sciencedirect.com/science/article/pii/S016344532)
BackgroundIn late 2023, the first human case caused by an H10N5 avian influenza virus (AIV) was diagnosed in China. H10Ny AIVs have been identified in various poultry and wild birds in Eurasia, the Americas, ... Taeyong Kwon, etc.,al. [preprint]Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. https://doi.org/10.1101/2025.03.04.641414. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.04.641414 (via https://www.biorxiv.org/content/10.1101/2025.03.04.641414v1)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching at least 16 states and at least 950 dairy herds in the United ... Cassandra J Field, etc.,al. [preprint]Defining the transmissible dose 50%, the donor inoculation dose that results in airborne transmission to 50% of contacts, for two pandemic influenza viruses in ferrets. https://doi.org/10.1101/2025.03.04.641289. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.04.641289 (via https://www.biorxiv.org/content/10.1101/2025.03.04.641289v1)
Ferrets are widely used to model airborne transmission of influenza viruses in humans. Airborne transmission is evaluated by infecting donor ferrets with a high virus dose (106 infectious units) and monitoring ... Neda Nasheri, etc.,al. [preprint]Examining the Survival of A(H5N1) Influenza Virus in Thermised Whole Cow Milk. https://doi.org/10.1101/2025.03.05.641644. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.05.641644 (via https://www.biorxiv.org/content/10.1101/2025.03.05.641644v1)
The recent spillover events of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b to dairy cattle, and high viral shedding in the milk from infected animals, has created concern that milk ... Pardo-Roa, C., Nelson, M.I., Ariyama, N. et al. Cross-species and mammal-to-mammal transmission of clade 2.3.4.4b highly pathogenic avian influenza A/H5N1 with PB2 adaptations. Nat Commun 16, 2232 (2025). Abstract
submitted by kickingbird at Mar, 6, 2025 from Nat Commun 16, 2232 (2025) (via https://www.nature.com/articles/s41467-025-57338-z)
Highly pathogenic H5N1 avian influenza viruses (HPAIV) belonging to lineage 2.3.4.4b emerged in Chile in December 2022, leading to mass mortality events in wild birds, poultry, and marine mammals and one ... Qianqian Li, etc.,al. [preprint]Dominant substitutions underlying the antigenic evolution of H5 influenza virus. https://doi.org/10.21203/rs.3.rs-6040842/v1. Abstract
submitted by kickingbird at Mar, 5, 2025 from https://doi.org/10.21203/rs.3.rs-6040842/v1 (via https://www.researchsquare.com/article/rs-6040842/v1)
Highly pathogenic avian influenza (HPAI) H5 viruses have recently been documented in mammals including humans, posing a major threat to global public health. To prevent a potential H5 pandemic, it is critical ... Li S, Chu L, Zhang Y, Yu Y and Wang G. Genetic characterization of an H3N2 canine influenza virus strain in China in 2023-acquisition of novel human-like amino acid substitutions. Front. Vet. Sci. 12:1552115. Abstract
submitted by kickingbird at Mar, 4, 2025 from Front. Vet. Sci. 12:1552115 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Around 2005, influenza A virus (IAV) once again crossed species barriers and established a stable lineage within canine populations. Currently, avian-origin H3N2 canine influenza virus (CIV) is the only ... Mahmoud Bayoumi, etc.,al. [preprint]Identification of Amino Acid Residues Responsible for Differential Replication and Pathogenicity of Avian Influenza Virus H5N1 Isolated from Human and Cattle in Texas, US. https://doi.org/10.1101/2025.03.01.640810. Abstract
submitted by kickingbird at Mar, 3, 2025 from https://doi.org/10.1101/2025.03.01.640810 (via https://www.biorxiv.org/content/10.1101/2025.03.01.640810v1)
Highly pathogenic avian influenza viruses (HPAIV) pose a serious public health concern. In March 2024, a first-time outbreak of HPAIV H5N1 in dairy cattle herds was reported in the United States (US). ... Hoang-Hai Nguyen, etc.,al. [preprint]WaveSeekerNet: Accurate Prediction of Influenza A Virus Subtypes and Host Source Using Attention-Based Deep Learning. https://doi.org/10.1101/2025.02.25.639900. Abstract
submitted by kickingbird at Mar, 2, 2025 from https://doi.org/10.1101/2025.02.25.639900 (via https://www.biorxiv.org/content/10.1101/2025.02.25.639900v1)
Background Influenza A virus (IAV) poses a significant threat to animal health globally, with its ability to overcome species barriers and cause pandemics. Rapid and accurate prediction of IAV subtypes ... Hugo Castelan-Sanchez, Art Poon. [preprint]Phylogenetic discordance cannot identify genomic reassortment events: a case study with the avian influenza virus H5Nx. https://doi.org/10.1101/2025.02.24.639875. Abstract
submitted by kickingbird at Mar, 2, 2025 from https://doi.org/10.1101/2025.02.24.639875 (via https://www.biorxiv.org/content/10.1101/2025.02.24.639875v1)
Recombination plays a central role in the evolution of the RNA virus genome, as it allows the exchange of genetic material between different viral lineages. Reassortment is a form of recombination specific ... Murray J, Nogales A, Martinez-Sobrido L, Martin DE. Evaluating Probenecid or Oseltamivir Inhibition of Influenza A Virus Replication Through Plaque Assay or Fluorescent Focus Assay Using Non-Structural Protein 1–H1N1 Venus Reporter Virus. Viruses. 2025; 17(3):335. Abstract
submitted by kickingbird at Mar, 2, 2025 from Viruses. 2025; 17(3):335 (via https://www.mdpi.com/1999-4915/17/3/335)
It is essential to understand the molecular mechanisms of influenza antiviral therapeutics to evaluate their efficacy. Virus plaque assays are commonly used to assess the antiviral effects of drugs on ... Yu X, Su N, Luo J, Zhang D, Zhang H, Duan M, Shi N. Long noncoding RNA USP30-AS1 promotes influenza A virus replication by enhancing PHB1 function. Vet Microbiol. 2025 Feb 26;303:110444. Abstract
submitted by kickingbird at Mar, 2, 2025 from Vet Microbiol. 2025 Feb 26;303:110444 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Long noncoding RNAs (lncRNAs) are important regulators of gene expression. Although evidence accumulated over the past decade shows that lncRNAs have key roles in the interaction between viruses and hosts, ... Zhu Y, Cong Y, Sun Y, Sheng S, Liu C, Jiang J, Li. Molecular patterns of matrix protein 1 (M1): A strong predictor of adaptive evolution in H9N2 avian influenza viruses. Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e24239. Abstract
submitted by kickingbird at Mar, 1, 2025 from Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e24239 (via https://www.pnas.org/doi/10.1073/pnas.2423983122)
The H9N2 subtype of avian influenza virus (AIV) emerges as a significant member of the influenza A virus family. However, the varying degrees of epidemiological dominance among different lineages or clades ... Kirill Vasilev, etc.,al. [preprint]Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza virus vaccine adjuvanted with bacterial cell membrane-derived adjuvants. https://doi.org/10.1101/2025.02.26.640278. Abstract
submitted by kickingbird at Feb, 27, 2025 from https://doi.org/10.1101/2025.02.26.640278 (via https://www.biorxiv.org/content/10.1101/2025.02.26.640278v1)
Influenza virus neuraminidase (NA) has emerged as a promising vaccine candidate due to its relatively stable antigenic structure and the ability of NA-specific antibodies to provide cross-protection within ... 7184 items, 20/Page, Page[70/360][|<<] [|<] [61] [62] [63] [64] [65] [66] [67] [68] [69] [70] [>|] [>>|] |
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