Kieran TJ, Sun X, Maines TR, Belser JA. Optimal thresholds and key parameters for predicting influenza A virus transmission events in ferrets. Npj Viruses. 2024;2(1):64. Abstract
submitted by kickingbird at Dec, 13, 2024 from Npj Viruses. 2024;2(1):64 (via https://www.nature.com/articles/s44298-024-00074-w)
Although assessments of influenza A virus transmissibility in the ferret model play a critical role in pandemic risk evaluations, few studies have investigated which virological data collected from virus-inoculated ... Borkenhagen LK, Runstadler JA. Examining the Influenza A Virus Sialic Acid Binding Preference Predictions of a Sequence-Based Convolutional Neural Network. Influenza Other Respir Viruses. 2024 Dec;18(12):e7. Abstract
submitted by kickingbird at Dec, 13, 2024 from Influenza Other Respir Viruses. 2024 Dec;18(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70044)
Background: Though receptor binding specificity is well established as a contributor to host tropism and spillover potential of influenza A viruses, determining receptor binding preference of a specific ... Joao Paulo Portela Catani, etc.,al. [preprint]The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020. https://doi.org/10.1101/2024.12.10.627724. Abstract
submitted by kickingbird at Dec, 12, 2024 from https://doi.org/10.1101/2024.12.10.627724 (via https://www.biorxiv.org/content/10.1101/2024.12.10.627724v1)
The clinical burden caused by influenza can be mitigated by the prophylactic use of seasonal influenza vaccines. Their immunogen composition is revised biannually to optimally match the antigenic drift ... Elyse Stachler, etc.,al. [preprint]Establishing methods to monitor H5N1 influenza virus in dairy cattle milk. https://doi.org/10.1101/2024.12.04.24318491. Abstract
submitted by kickingbird at Dec, 11, 2024 from https://doi.org/10.1101/2024.12.04.24318491 (via https://www.medrxiv.org/content/10.1101/2024.12.04.24318491v)
Highly Pathogenic Avian Influenza strain H5N1 has caused a multi-state outbreak among US dairy cattle, spreading across 15 states and infecting hundreds of herds since its onset. We rapidly developed and ... Hubbard LE, Stelzer EA, Poulson RL, Kolpin DW, Sza. Development of a Large-Volume Concentration Method to Recover Infectious Avian Influenza Virus from the Aquatic Environment. Viruses. 2024; 16(12):1898. Abstract
submitted by kickingbird at Dec, 11, 2024 from Viruses. 2024; 16(12):1898 (via https://www.mdpi.com/1999-4915/16/12/1898)
Since late 2021, outbreaks of highly pathogenic avian influenza virus have caused a record number of mortalities in wild birds, domestic poultry, and mammals in North America. Wetlands are plausible environmental ... Ramos-Martínez I, Ramos-Martínez E, Saavedra-Monta. Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs. Animals. 2024; 14(23):3467. Abstract
submitted by kickingbird at Dec, 11, 2024 from Animals. 2024; 14(23):3467 (via https://www.mdpi.com/2076-2615/14/23/3467)
Influenza A is a zoonotic disease that affects dogs. In this work, we performed a meta-analysis of the prevalence and seroprevalence of reports from all over the world. We found a combined seroprevalence ... Yong Zhou, etc.,al. Origin, spread, and interspecies transmission of a dominant genotype of BJ/94 lineage H9N2 avian influenza viruses with increased threat. Virus Evolution, veae106. Abstract
submitted by kickingbird at Dec, 11, 2024 from Virus Evolution, veae106 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The H9N2 subtype of avian influenza viruses (AIVs) is widely prevalent in poultry and wild birds globally, with occasional transmission to humans. In comparison to other H9N2 lineages, the BJ/94 lineage ... Feng Wen, etc.,al. Novel human-type receptor-binding H5N1 virus in live poultry markets, China. The Lancet Microbe. Abstract
submitted by kickingbird at Dec, 11, 2024 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
Avian influenza viruses represent a considerable public health risk, with the capability to cross species barriers and cause severe disease in humans. The emergence of H5N1 subtype of highly pathogenic ... Ankerhold J, Kessler S, Beer M, Schwemmle M, Cimin. Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024. Emerg Infect Dis. 2025 Jan. Abstract
submitted by kickingbird at Dec, 11, 2024 from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1236_article)
We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and in MxA-transgenic mice. However, H5N1 ... Sarsenov R, Babenko D, Kamalova D, Amirgazin A, Be. Complete genome sequence of a human influenza a virus (H1N1) detected in Kazakhstan in the fall of 2022. Microbiol Resour Announc. 2024 Dec 10:e0104024. Abstract
submitted by kickingbird at Dec, 11, 2024 from Microbiol Resour Announc. 2024 Dec 10:e0104024 (via https://journals.asm.org/doi/10.1128/mra.01040-24)
An Orthomyxoviridae Alphainfluenza virus Influenza A virus strain, A/Kazakhstan/Flu-H11-6/2022(H1N1), was isolated in Karaganda, Central Kazakhstan during a study of acute respiratory infections among ... Yin Y, Kan X, Miao X, Sun Y, Chen S, Qin T, Ding C. H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. PLoS Pathog. 2024 Dec 9;20(12):e1012748. Abstract
submitted by kickingbird at Dec, 10, 2024 from PLoS Pathog. 2024 Dec 9;20(12):e1012748 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial ... Xia M, Huang P, Vago FS, Jiang W, Tan M. Pseudovirus nanoparticles targeting the receptor binding HA1 domains of influenza viruses elicited high HA1-specific antibody responses and protected mice against mortality caused by influenza virus c. Vaccine. 2024 Dec 7:126585. Abstract
submitted by kickingbird at Dec, 9, 2024 from Vaccine. 2024 Dec 7:126585 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The continually high disease burden of influenza and the relatively low effectiveness of current influenza vaccines call for enhanced vaccine strategies. We previously generated unique S-HA1 pseudovirus ... Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilb. Marked Neurotropism and Potential Adaptation of H5N1 Clade 2.3.4.4.b Virus in Naturally Infected Domestic Cats. Emerg Microbes Infect. 2024 Dec 9:2440498. Abstract
submitted by kickingbird at Dec, 9, 2024 from Emerg Microbes Infect. 2024 Dec 9:2440498 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. ... Gunasekara E, Hair-Bejo M, Aini I, Omar AR. Molecular characterisation of novel reassortants of the G57 genotype of low-pathogenic avian influenza H9N2 virus isolated from poultry farms in Malaysia. Arch Virol. 2024 Dec 7;170(1):3. Abstract
submitted by kickingbird at Dec, 8, 2024 from Arch Virol. 2024 Dec 7;170(1):3 (via https://link.springer.com/article/10.1007/s00705-024-06159-4)
In late 2017, Malaysia reported repeated outbreaks of low-pathogenic avian influenza virus (LPAI) H9N2 infections in commercial poultry flocks. Two H9N2 viruses, A/chicken/Malaysia/Negeri Sembilan/UPM994/2018 ... Isabela Carvalho Brcko, etc.,al. Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis. Virus Evolution, veae102. Abstract
submitted by kickingbird at Dec, 7, 2024 from Virus Evolution, veae102 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Influenza A and B viruses represent significant global health threats, contributing substantially to morbidity and mortality rates. However, a comprehensive understanding of the molecular epidemiology ... Jiawei Luo, etc.,al. The PB1 protein of H9N2 influenza A virus inhibits antiviral innate immunity by targeting MAVS for TRIM25-mediated autophagic degradation. Poultry Science. Abstract
submitted by kickingbird at Dec, 7, 2024 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. However, the regulatory mechanisms remain not fully understood. ... Nuo Xu, etc.,al. The evolution of hemagglutinin-158 and neuraminidase-88 glycosylation sites modulates antigenicity and pathogenicity of clade 2.3.2.1 H5N1 avian influenza viruses. Veterinary Microbiology. Abstract
submitted by kickingbird at Dec, 7, 2024 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Clade 2.3.2.1 of the H5N1 avian influenza virus (AIV) evolved into several subclades. However, the effect of glycosylation on the biological characteristics of hemagglutinin (HA) and/or neuraminidase (NA) ... Matthew L Turnbull, etc.,al. [preprint]POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS. https://doi.org/10.1101/2024.11.29.626120. Abstract
submitted by kickingbird at Dec, 6, 2024 from https://doi.org/10.1101/2024.11.29.626120 (via https://www.biorxiv.org/content/10.1101/2024.11.29.626120v1)
H5N1 avian influenza virus (lineage 2.3.4.4b, B3.13 genotype) has caused, unexpectedly, a large outbreak in dairy cattle in North America. It is critical to ascertain how this virus has specifically adapted ... Lv H, Teo QW, Lee C-CD, Liang W, Choi D, Mao KJ, A. Differential antigenic imprinting effects between influenza H1N1 hemagglutinin and neuraminidase in a mouse model. J Virol. 2024 Dec 5:e0169524. Abstract
submitted by kickingbird at Dec, 6, 2024 from J Virol. 2024 Dec 5:e0169524 (via https://journals.asm.org/doi/10.1128/jvi.01695-24)
Understanding how immune history influences influenza immunity is essential for developing effective vaccines and therapeutic strategies. This study examines the antigenic imprinting of influenza hemagglutinin ... Lin TH, Zhu X, Wang S, Zhang D, McBride R, Yu W, B. A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors. Science. 2024 Dec 6;386(6726):1128-1134. Abstract
submitted by kickingbird at Dec, 6, 2024 from Science. 2024 Dec 6;386(6726):1128-1134 (via https://www.science.org/doi/10.1126/science.adt0180)
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-human ... 6895 items, 20/Page, Page[65/345][|<<] [|<] [61] [62] [63] [64] [65] [66] [67] [68] [69] [70] [>|] [>>|] |
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