Kuang-Yu Chen, etc.,al. [preprint]Influenza A virus initiates genome selection through promoter-dependent nuclear export. https://doi.org/10.64898/2026.08.14.744863. Abstract
submitted by kickingbird at Aug, 22, 2026 from https://doi.org/10.64898/2026.08.14.744863 (via https://www.biorxiv.org/content/10.64898/2026.08.14.744863v1)
Influenza A virus replicates its segmented RNA genome in the nucleus in the context of viral ribonucleoprotein (vRNP) complexes. Newly synthesised vRNPs are exported to the cytoplasm for virion assembly, ... Vedhika Raghunathan, etc.,al. [preprint]Within-host antigenic selection of influenza A virus dominates over stochasticity but is limited by fitness tradeoffs and timing of the immune response. https://doi.org/10.64898/2026.08.19.745600. Abstract
submitted by kickingbird at Aug, 22, 2026 from https://doi.org/10.64898/2026.08.19.745600 (via https://www.biorxiv.org/content/10.64898/2026.08.19.745600v1)
Despite antigenic evolution at the global scale, positive selection of influenza virus antigenic variants is not readily observed within hosts. Here, we tested the extent to which fitness tradeoffs, the ... Jiayun Yang, etc.,al. [preprint]Emerging Haemagglutinin Mutations in Bovine-origin H5N1 Influenza Viruses from Humans and Cattle Retain Avian Receptor Binding with Increased Stability. https://doi.org/10.64898/2026.08.18.745528. Abstract
submitted by kickingbird at Aug, 22, 2026 from https://doi.org/10.64898/2026.08.18.745528 (via https://www.biorxiv.org/content/10.64898/2026.08.18.745528v1)
The current H5N1 panzootic has seen an unprecedented host range expansion, including sustained circulation in US dairy cattle, detected in March 2024. By July 2026, infections had been reported on more ... Nakamura K, Nagai T, Ishiguro H, Kobayashi K, Naka. Evaluation of the Collection Efficiency of a Wet-Type Electrostatic Precipitator for Aerosolized Influenza A Virus. Microorganisms. 2026; 14(8):1863. Abstract
submitted by kickingbird at Aug, 21, 2026 from Microorganisms. 2026; 14(8):1863 (via https://www.mdpi.com/2076-2607/14/8/1863)
Airborne viruses are a key driver of infectious disease transmission, highlighting the importance of reliable detection in public health surveillance. As atmospheric viral concentrations are very low, ... Wu H, Yang F, Wang P, Fu J, Zhang J, Guo J, Cheng. A bispecific antibody targeting conserved hemagglutinin epitopes confers broad protection against H7 avian influenza and accelerates viral clearance via localized respiratory delivery. Emerg Microbes Infect. 2026 Dec;15(1):2713326. Abstract
submitted by kickingbird at Aug, 20, 2026 from Emerg Microbes Infect. 2026 Dec;15(1):2713326 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
The continuous antigenic drift of zoonotic H7 avian influenza viruses remains a significant global public health threat. While monoclonal antibodies (mAbs) targeting the hemagglutinin (HA) head offer potent ... Yang C, Luo T, Li Y, Chen Z, Lin Z, Zhang F, Wang. Integrated Simulation for Identifying the Key Driver of Strain-Specific Airborne Infectivity of Influenza Viruses. Environ Sci Technol. 2026 Aug 18;60(32):22737-2274. Abstract
submitted by kickingbird at Aug, 19, 2026 from Environ Sci Technol. 2026 Aug 18;60(32):22737-2274 (via https://pubs.acs.org/esthag/article-abstract/doi/10.1021/acs)
Airborne transmission plays a central role in the spread of seasonal influenza; however, the determinants governing strain-specific airborne infectivity remain poorly understood. Here, we integrated exposure-infection ... Chang-Gi Jeong, etc.,al. Genomic and Clinicopathological Characterization of a Reassortant HPAI H5N1 (Clade 2.3.4.4b) in an Endangered Cinereous Vulture (Aegypius monachus) in South Korea, 2026. Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at Aug, 19, 2026 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/2623621)
Clade 2.3.4.4b highly pathogenic avian influenza viruses (HPAIVs) continue to circulate widely in East Asia and undergo frequent reassortment in wild birds. Raptors are regarded as spillover hosts that ... Linda Benincasa, etc.,al. [preprint]MDCK-VHG and MDCK-SIAT1: set-up for improving influenza virus propagation. https://doi.org/10.1099/acmi.0.001297.v1. Abstract
submitted by kickingbird at Aug, 19, 2026 from https://doi.org/10.1099/acmi.0.001297.v1 (via https://www.microbiologyresearch.org/content/journal/acmi/10)
The identification of an optimized cellular platform for the propagation of influenza viruses remains a core aim in vaccine development strategies and study of influenza viruses. Worldwide, MDCK cells ... Silje Granstad, etc.,al. Multiple introductions of highly pathogenic avian influenza viruses into the High Arctic: Svalbard and Jan Mayen, 2022–2025. Journal of General Virology 107, 002305 (2026). Abstract
submitted by kickingbird at Aug, 19, 2026 from Journal of General Virology 107, 002305 (2026) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Between 2022 and 2025, highly pathogenic avian influenza viruses (HPAIVs) of clade 2.3.4.4b, including four distinct H5 Eurasian (EA) genotypes, were detected in wild birds and mammals in the Svalbard ... Nora Pisanic, etc.,al. [preprint]Livestock production intensity and mucosal IgA and IgG responses to H5N1 highly pathogenic avian influenza A virus, North Carolina, 2021-2022. https://doi.org/10.64898/2026.08.06.26359901. Abstract
submitted by kickingbird at Aug, 18, 2026 from https://doi.org/10.64898/2026.08.06.26359901 (via https://www.medrxiv.org/content/10.64898/2026.08.06.26359901)
Background Direct livestock exposure is a risk factor for zoonotic influenza, including H5N1 highly pathogenic avian influenza (HPAI) A virus. But whether living in regions of high poultry and swine production ... Ahmed M. Elsayed, etc.,al. [preprint]Enhanced Pathogenicity and Contact Transmissibility of Human-origin Avian Influenza H5N1 Clade 2.3.4.4b Genotype B3.13 Compared to D1.1 in Ferrets. https://doi.org/10.64898/2026.08.10.744032. Abstract
submitted by kickingbird at Aug, 18, 2026 from https://doi.org/10.64898/2026.08.10.744032 (via https://www.biorxiv.org/content/10.64898/2026.08.10.744032v1)
Since its emergence in 2020, multiple genotypes of the H5N1 clade 2.3.4.4b have been identified, with B3.13 and D1.1 emerging in the USA as two major and concerning genotypes. However, their relative pathogenicity ... Granstad S, T?nnessen R, Ytrehus B, Descamps S, Mo. Multiple introductions of highly pathogenic avian influenza viruses into the High Arctic: Svalbard and Jan Mayen, 2022-2025. J Gen Virol. 2026 Aug;107(8). Abstract
submitted by kickingbird at Aug, 18, 2026 from J Gen Virol. 2026 Aug;107(8) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Between 2022 and 2025, highly pathogenic avian influenza viruses (HPAIVs) of clade 2.3.4.4b, including four distinct H5 Eurasian (EA) genotypes, were detected in wild birds and mammals in the Svalbard ... Yasushi Suzuki, etc.,al. A novel candidate vaccine virus derived from Japan‘s first mammalian case of clade 2.3.4.4b A/H5N1 highly pathogenic avian influenza virus. Vaccine. Abstract
submitted by kickingbird at Aug, 18, 2026 from Vaccine (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The development of candidate vaccine viruses (CVVs) for pre-pandemic preparedness requires attenuation of pathogenicity while maintaining immunogenicity. In this study, we developed and characterized NIID-002, ... M. C. Chiu, S. Zhang, C. Li, et al. Generation of Nasal Cell-Derived Human Alveolar Organoids and Organoid-Macrophage Assembloids for in Vitro Lung Modeling. Advanced Science (2026): e77093. Abstract
submitted by kickingbird at Aug, 16, 2026 from Advanced Science (2026): e77093 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.77)
We established robust protocols to generate physiological and functional alveolar organoids (nsoAlvO) from readily accessible and expandable nasal cell-derived organoids, and alveolar macrophages (monoAM) ... Giacomo De Conti, etc.,al. [preprint]A GIS-based framework for standardized environmental characterization in One-Health surveillance: a case study of HPAI monitoring in wetlands. https://doi.org/10.21203/rs.3.rs-10456544/v1. Abstract
submitted by kickingbird at Aug, 16, 2026 from https://doi.org/10.21203/rs.3.rs-10456544/v1 (via https://www.researchsquare.com/article/rs-10456544/v1)
BackgroundThe Highly Pathogenic Avian Influenza (HPAI) panzootic caused by H5 viruses of clade 2.3.4.4b is constantly re-shaping disease ecology in terms of spatio-temporal spread and host spectrum. Because ... Denise I.T. Kuok, etc.,al. Assessment of influenza virus and coronavirus tropism, replication competence and disease severity in ex vivo and in vitro cultures of the human respiratory tract. Journal of General Virology 107, 002281 (2026) Jul. Abstract
submitted by kickingbird at Aug, 15, 2026 from Journal of General Virology 107, 002281 (2026) Jul (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The emergence of animal influenza viruses circulating in poultry and human populations poses a significant public health threat, yet current risk assessment tools that connect surveillance data to human ... Mohammed Nooruzzaman, etc.,al. Characterization of bovine-derived H5N1 viruses expressing fluorescent and luminescent reporter proteins. Journal of General Virology 107, 002298 (2026). Abstract
submitted by kickingbird at Aug, 15, 2026 from Journal of General Virology 107, 002298 (2026) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses present a broad host range, with recent spillover and sustained transmission in dairy cattle reported in the USA. Replication-competent reporter ... Wille M, Abbott W, Day D, Deng YM, Dong X, Gibson. Skuas as sentinels of high pathogenicity avian influenza H5N1 on the Antarctic Peninsula in the 2024/2025 austral summer. Microb Genom. 2026 Aug;12(8). Abstract
submitted by kickingbird at Aug, 15, 2026 from Microb Genom. 2026 Aug;12(8) (via https://www.microbiologyresearch.org/content/journal/mgen/10)
Despite Antarctica's geographic isolation, the first incursion of high pathogenicity avian influenza (HPAI) H5N1 was detected in the 2023/2024 austral summer. Surveillance for HPAI H5N1 in Antarctica remains ... Dema B, Ulaszewska M, Lilley A, Lofts A, Bhasin R,. Assessment of Humoral Immunogenicity of ChAdOx1 H5 HA Influenza Vaccine for Dairy Cattle. Vaccines. 2026; 14(8):691. Abstract
submitted by kickingbird at Aug, 14, 2026 from Vaccines. 2026; 14(8):691 (via https://www.mdpi.com/2076-393X/14/8/691)
Background/objectives: The emergence of highly pathogenic avian influenza A (H5N1) virus infections in dairy cattle in the United States revealed a novel mammalian host and a potential transmission pathway ... Rovito SW, Chen P-L, Yang G, Writt HN, Zalla AN, D. An In Vitro Screen Identifies H1 Influenza Hemagglutinin Substitutions That Alter mRNA-LNP Vaccine Responses Against the Stalk Domain. Vaccines. 2026; 14(8):701. Abstract
submitted by kickingbird at Aug, 14, 2026 from Vaccines. 2026; 14(8):701 (via https://www.mdpi.com/2076-393X/14/8/701)
Background: Conformational stability has been shown to modulate the immunogenicity of structural class 1 viral fusion glycoproteins, yet the relationship between influenza A hemagglutinin (HA) stability ... 7180 items, 20/Page, Page[6/359][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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