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2025-12-5 21:50:31
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Louis S, Mark-Carew M, Biggerstaff M, et al. Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases - United Stat. MMWR Morb Mortal Wkly Rep 2024;73:804–809.  Abstract  
submitted by kickingbird at Sep, 20, 2024 from MMWR Morb Mortal Wkly Rep 2024;73:804–809 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7337a1.htm)
As part of the response to the highly pathogenic avian influenza A(H5N1) virus outbreak in U.S. cattle and poultry and the associated human cases, CDC and partners are monitoring influenza A virus levels ...

Sircy LM, Ramstead AG, Gibbs LC, Joshi H, Baessler. Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection. PLoS Pathog. 2024 Sep 16;20(9):e1011639.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from PLoS Pathog. 2024 Sep 16;20(9):e1011639 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Current influenza vaccine strategies have yet to overcome significant obstacles, including rapid antigenic drift of seasonal influenza viruses, in generating efficacious long-term humoral immunity. Due ...

Ahlstrom CA, Torchetti MK, Lenoch J, Beckmen K, Bo. Genomic characterization of highly pathogenic H5 avian influenza viruses from Alaska during 2022 provides evidence for genotype-specific trends of spatiotemporal and interspecies dissemination. Emerg Microbes Infect. 2024 Sep 17:2406291.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from Emerg Microbes Infect. 2024 Sep 17:2406291 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The ongoing panzootic of highly pathogenic H5 clade 2.3.4.4b avian influenza (HPAI) spread to North America in late 2021, with detections of HPAI viruses in Alaska beginning in April 2022. HPAI viruses ...

Yue X, Zhong C, Cao R, Liu S, Qin Z, Liu L, Zhai Y. CircRNA based multivalent neuraminidase vaccine induces broad protection against influenza viruses in mice. NPJ Vaccines. 2024 Sep 16;9(1):170.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from NPJ Vaccines. 2024 Sep 16;9(1):170 (via https://www.nature.com/articles/s41541-024-00963-4)
Developing broad-spectrum influenza vaccines is crucial for influenza control and potential pandemic preparedness. Here, we reported a novel vaccine design utilizing circular RNA (circRNA) as a delivery ...

Benito AA, Monteagudo LV, Lázaro-Gaspar S, Mazas-C. Detection and subtyping of influenza A virus in porcine clinical samples from Spain in 2020. Virology. 2024 Sep 8;600:110223.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from Virology. 2024 Sep 8;600:110223 (via https://www.sciencedirect.com/science/article/pii/S004268222)
A total of 1019 samples collected on 726 Spanish swine farms suffering from outbreaks of respiratory disease were screened for influenza A viruses (IAVs) using a RT-qPCR method. A subset of positive samples ...

Root JJ, Porter SM, Lenoch JB, Ellis JW, Bosco-La. Susceptibilities and viral shedding of peridomestic wildlife infected with clade 2.3.4.4b highly pathogenic avian influenza virus (H5N1). Virology. 2024 Sep 5;600:110231.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from Virology. 2024 Sep 5;600:110231 (via https://www.sciencedirect.com/science/article/pii/S004268222)
We tested the ability of six peridomestic wildlife species to replicate a highly pathogenic (HP) clade 2.3.4.4b AIV (H5N1) isolated in the U.S. during 2022. All tested species replicated and shed virus, ...

Bahakel H, Spieker AJ, Hayek H, Schuster JE, Hamda. Immunogenicity and Reactogenicity of High-dose or Standard-dose Influenza Vaccine in a Second Consecutive Influenza Season. J Infect Dis. 2024 Sep 16:jiae454.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from J Infect Dis. 2024 Sep 16:jiae454 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Background: Pediatric hematopoietic cell transplant (HCT) recipients are at high-risk for morbidity from influenza virus infection. We demonstrated in a primary phase II randomized controlled trial that ...

Richard J Webby, Timothy M Uyeki. An Update on Highly Pathogenic Avian Influenza A(H5N1) Virus, Clade 2.3.4.4b. The Journal of Infectious Diseases, jiae379.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from The Journal of Infectious Diseases, jiae379 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Since the resurgence of highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, during 2021, these viruses have spread widely among birds worldwide, causing poultry outbreaks and infections ...

Hesham A. Sultan, etc.,al. Experimental Infection of Clades 2.2.1.2 (H5N1) and 2.3.4.4b (H5N8) of Highly Pathogenic Avian Influenza Virus Infection in Commercial broilers. Comparative Immunology, Microbiology and Infectiou.  Abstract  
submitted by kickingbird at Sep, 16, 2024 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
In this study the pathogenicity, infectivity, and transmissibility of H5N1 highly pathogenic avian influenza (HPAI) clade 2.2.1.2 and H5N8 HPAI clade 2.3.4.4b viruses were evaluated in commercial broilers ...

Kwon T, Gebhardt JT, Lyoo EL, Nooruzzaman M, Gaudr. Bovine Highly Pathogenic Avian Influenza Virus Stability and Inactivation in the Milk Byproduct Lactose. Viruses. 2024; 16(9):1451.  Abstract  
submitted by kickingbird at Sep, 16, 2024 from Viruses. 2024; 16(9):1451 (via https://www.mdpi.com/1999-4915/16/9/1451)
The recent incursion of highly pathogenic influenza viruses into dairy cattle opens new insights for influenza virus ecology and its interspecies transmission and may have a significant impact on public ...

Phuong do Q, Dung NT, J?rgensen PH, Van DT, Tung D. Virulence of H5N1 influenza virus in Cattle Egrets (Bubulcus ibis). J Wildl Dis. 2011 Apr;47(2):314-20.  Abstract  
submitted by kickingbird at Sep, 15, 2024 from J Wildl Dis. 2011 Apr;47(2):314-20 (via https://meridian.allenpress.com/jwd/article/47/2/314/124162/)
In Vietnam, Cattle Egrets (Bubulcus ibis) are common in a variety of habitats, such as freshwater marshes, beaches, and paddy fields. They are also found associated with cattle (Bos spp.) and occasionally ...

John Sidney, etc.,al. [preprint]Targets of influenza Human T cell response are mostly conserved in H5N1. https://doi.org/10.1101/2024.09.09.612060.  Abstract  
submitted by kickingbird at Sep, 14, 2024 from https://doi.org/10.1101/2024.09.09.612060 (via https://www.biorxiv.org/content/10.1101/2024.09.09.612060v1)
Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns ...

Michelle Wille and others. Contrasting dynamics of two incursions of low pathogenicity avian influenza virus into Australia. Virus Evolution, veae076.  Abstract  
submitted by kickingbird at Sep, 12, 2024 from Virus Evolution, veae076 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The current panzootic of high pathogenicity avian influenza virus H5N1 demonstrates how viral incursions can have major ramifications for wildlife and domestic animals. Herein, we describe the recent incursion ...

Marchi S, Bruttini M, Milano G, Manini I, Chironna. Prevalence of Influenza B/Yamagata Viruses From Season 2012/2013 to 2021/2022 in Italy as an Indication of a Potential Lineage Extinction. Influenza Other Respir Viruses. 2024 Sep;18(9):e13.  Abstract  
submitted by kickingbird at Sep, 12, 2024 from Influenza Other Respir Viruses. 2024 Sep;18(9):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13359)
Background: Influenza B/Yamagata viruses exhibited weak antigenic selection in recent years, reducing their prevalence over time and requiring no update of the vaccine component since 2015. To date, no ...

Sharmada Swaminath, etc.,al. [preprint]Efficient genome replication in influenza A virus requires NS2 and sequence beyond the canonical promoter. https://doi.org/10.1101/2024.09.10.612348.  Abstract  
submitted by kickingbird at Sep, 12, 2024 from https://doi.org/10.1101/2024.09.10.612348 (via https://www.biorxiv.org/content/10.1101/2024.09.10.612348v1)
Influenza A virus encodes promoters in both the sense and antisense orientations. These support the generation of new genomes, antigenomes, and mRNA transcripts. Using minimal replication assays—transfections ...

Hailey Robertson, etc.,al. [preprint]Understanding Ecological Systems Using Knowledge Graphs: An Application to Highly Pathogenic Avian Influenza. https://doi.org/10.1101/2024.09.05.611483.  Abstract  
submitted by kickingbird at Sep, 12, 2024 from https://doi.org/10.1101/2024.09.05.611483 (via https://www.biorxiv.org/content/10.1101/2024.09.05.611483v1)
Ecological systems are complex. Representing heterogeneous knowledge about ecological systems is a pervasive challenge because data are generated from many subdisciplines, exist in disparate sources, and ...

Shen J, Zhang H, Sun X, Zhang Y, Wang M, Guan M, L. Evolution and biological characteristics of H11 avian influenza viruses isolated from migratory birds and pigeons. Emerg Microbes Infect. 2024 Dec;13(1):2398641.  Abstract  
submitted by kickingbird at Sep, 10, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2398641 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The emergence of novel avian influenza reassortants in wild birds in recent years is a public health concern. However, the viruses that circulate in migratory birds are not fully understood. In this study, ...

Jourdan M. Ringenberg, etc.,al. Prevalence of Avian Influenza Virus in Atypical Wild Birds Host Groups during an Outbreak of Highly Pathogenic Strain EA/AM H5N1. Transboundary and Emerging Diseases, 2024.  Abstract  
submitted by kickingbird at Sep, 9, 2024 from Transboundary and Emerging Diseases, 2024 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/4009552)
The global outbreak of highly pathogenic avian influenza (HPAI) H5N1 Eurasian lineage goose/Guangdong clade 2.3.4.4b virus that was detected in North America in 2021 is the largest in history and has significantly ...

Puduo Zhu, etc.,al. Characterization and Pathogenicity of Novel Reassortment H6N6 Avian Influenza Viruses in Southern China. Transboundary and Emerging Diseases, 2024.  Abstract  
submitted by kickingbird at Sep, 9, 2024 from Transboundary and Emerging Diseases, 2024 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/4005909)
The H6N6 avian influenza virus (AIV) subtype is one of the most frequently isolated subtypes in poultry, and it has a broad host range. Some strains can overcome species barriers for transmission and infect ...

Giménez-Lirola LG, Cauwels B, Mora-Díaz JC, Magtot. Detection and Monitoring of Highly Pathogenic Influenza A Virus 2.3.4.4b Outbreak in Dairy Cattle in the United States. Viruses. 2024; 16(9):1376.  Abstract  
submitted by kickingbird at Sep, 9, 2024 from Viruses. 2024; 16(9):1376 (via https://www.mdpi.com/1999-4915/16/9/1376)
The emergence and spread of highly pathogenic avian influenza virus A subtype H5N1 (HP H5N1-IAV), particularly clade H5N1 2.3.4.4b, pose a severe global health threat, affecting various species, including ...

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