Jesse Bloom. Near-real time mapping of the human neutralizing antibody landscape to influenza to inform vaccine selection. Options for Control of Influenza Meeting August 30. Abstract
submitted by kickingbird at Aug, 30, 2026 from Options for Control of Influenza Meeting August 30 (via https://slides.com/jbloom/options2026)
[presentations] options2026 Near-real time mapping of the human neutralizing antibody landscape to influenza to inform vaccine selection. Brogaard L, Laybourn HA, Kristensen C, Welner S, L. Site-specific microRNA responses in lungs of pigs depend on the host-adaptation of H1N1 influenza A virus. Virology. 2026 Aug 27;624:111053. Abstract
submitted by kickingbird at Aug, 30, 2026 from Virology. 2026 Aug 27;624:111053 (via https://www.sciencedirect.com/science/article/pii/S004268222)
Cross-species transmission of influenza A virus (IAV) represents a major risk for emergence of new pandemics, however, the host molecular responses invoked by cross-species IAV infection remain incompletely ... Guo, Yunfei, Yang, Zhonglong, Yang, Hui, Miao, Xin. A Multi-Reassortant H3N8 Avian Influenza Virus Derived From Migratory Birds in Eastern China Exhibits Cross-Species Transmission Potential. Transboundary and Emerging Diseases, 2026, 9889145. Abstract
submitted by kickingbird at Aug, 30, 2026 from Transboundary and Emerging Diseases, 2026, 9889145 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/9889145)
Migratory birds are one of the main reservoirs and long-distance transmission vectors of avian influenza viruses (AIVs). A migratory-bird-origin H3N8 subtype AIV (A/wild bird/Huadong/sy17/2024, hereafter ... Bicong Wu, etc.,al. Environmental circulation of multiple avian influenza subtypes and potential association with human infections in central China. Front. Cell. Infect. Microbiol.. Abstract
submitted by kickingbird at Aug, 30, 2026 from Front. Cell. Infect. Microbiol. (via https://www.frontiersin.org/journals/cellular-and-infection-)
Avian influenza viruses (AIVs) continue to circulate in live poultry markets (LPMs), posing potential risks for zoonotic exposure. To investigate the environmental circulation of AIVs and their potential ... Mishina M, Horn CM, Ende Z, Mishin V, Holiday C, S. Memory B Cell Repertoire of a Repeatedly Vaccinated Individual Includes Influenza Hemagglutinin-Specific Cross-Group Binders with Affinity Beyond A(H1N1)pdm09 and A(H3N2) Seasonal Strains. Vaccines. 2026; 14(9):742. Abstract
submitted by kickingbird at Aug, 29, 2026 from Vaccines. 2026; 14(9):742 (via https://www.mdpi.com/2076-393X/14/9/742)
Background/Objectives: Humans are primarily infected by two distinct seasonal influenza A virus (IAV) subtypes, A(H1N1)pdm09 and A(H3N2). Because IAV mutates rapidly, it continuously escapes existing protective ... Alymova IV, Mekonnen B, Wang D, Kamal RP, Tzeng W,. N-linked glycosylation sites with low occupancy support sustained circulation of the A(H3N2) influenza A virus in the human population. J Virol 0:e00662-26. Abstract
submitted by kickingbird at Aug, 29, 2026 from J Virol 0:e00662-26 (via https://journals.asm.org/doi/10.1128/jvi.00662-26)
Glycosylation of the influenza A virus hemagglutinin is crucial for viral fitness and immune evasion. The hemagglutinin of contemporary human A(H3N2) influenza A viruses is extensively glycosylated with ... Zhenghan Luo, etc.,al. Establishment and Preliminary Evaluation of an RT-ERA Combined with CRISPR/Cas12a Assay for Detection of H5 and H7 Influenza Viruses. Front. Cell. Infect. Microbiol.. Abstract
submitted by kickingbird at Aug, 28, 2026 from Front. Cell. Infect. Microbiol. (via https://www.frontiersin.org/journals/cellular-and-infection-)
Background/ Objectives: Novel influenza A viruses (NIAV) infection is a zoonotic acute respiratory disease. The H5N1 and H7N9 subtypes cause high mortality, posing major public health threats. This study ... Edler P, Selva KJ, Reilly E, Aban M, Barr IG, Juno. Pre-existing systemic and nasal antibodies against avian H5 influenza A viruses vary according to childhood imprinting. mBio 0:e01892-26. Abstract
submitted by kickingbird at Aug, 28, 2026 from mBio 0:e01892-26 (via https://journals.asm.org/doi/10.1128/mbio.01892-26)
Avian influenza A viruses (IAVs) pose a constant pandemic threat, with the recent 2.3.4.4b clade of the H5 subtype causing high pathogenicity and spreading across animal species and geographic locations. ... Macauslane, K.L., Pegg, C.L., Seitanidou, J. et al. Neuraminidase and secretory pathway stress converge to remodel host glycosylation during influenza A virus infection. Commun Biol (2026). Abstract
submitted by kickingbird at Aug, 28, 2026 from Commun Biol (2026) (via https://link.springer.com/article/10.1038/s42003-026-10759-y)
Glycosylation is critical for viral-host cell interactions in influenza A virus (IAV) infection, but we lack a comprehensive understanding of how IAV infection shapes the host glycoproteome. Here, we performed ... Alkhamis, M.A., Fountain-Jones, N.M., Iglesias, I.. Complex interactions between ecological and host factors drive continental patterns of avian influenza outbreak risk in Eurasia and Africa. Sci Rep (2026). Abstract
submitted by kickingbird at Aug, 28, 2026 from Sci Rep (2026) (via https://link.springer.com/article/10.1038/s41598-026-68565-9)
Avian influenza viruses (AIV) have a remarkable capacity to adapt through rapid mutation and cross-species transmission, posing a major global pandemic threat. The distinct spatial patterns of outbreaks ... Thierry Boulinier, etc.,al. [preprint]Highly persistent antibody levels but limited population immunity in gannets after HPAI outbreak. https://doi.org/10.64898/2026.08.25.745523. Abstract
submitted by kickingbird at Aug, 27, 2026 from https://doi.org/10.64898/2026.08.25.745523 (via https://www.biorxiv.org/content/10.64898/2026.08.25.745523v1)
The recent large-scale circulation of High Pathogenicity Avian Influenza (HP AI) viruses H5Nx of clade 2.3.4.4b has been responsible for massive die-offs in wild species, notably in long-lived seabirds, ... Anna G Fairweather, etc.,al. [preprint]Predicting the Risk of Avian Influenza Zoonosis using Viral Genome Sequencing Data. https://doi.org/10.64898/2026.08.21.746166. Abstract
submitted by kickingbird at Aug, 27, 2026 from https://doi.org/10.64898/2026.08.21.746166 (via https://www.biorxiv.org/content/10.64898/2026.08.21.746166v1)
Avian Influenza viruses (AIVs) infect a broad host range despite having a natural reservoir in wild aquatic birds. Whilst most strains stay within their host species, some break the species barrier through ... Barre RS, Nath H, Nogales A, Abdelwhab EM, Elsayed. NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations. J Virol 0:e01099-26. Abstract
submitted by kickingbird at Aug, 27, 2026 from J Virol 0:e01099-26 (via https://journals.asm.org/doi/10.1128/jvi.01099-26)
Reporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host–pathogen interactions, and the identification and characterization of prophylactic ... L. Claire Gay, etc.,al. [preprint]IMPAIRED NEURAMINIDASE AND POLYMERASE ACTIVITIES CORRESPOND WITH LIMITED AEROSOL INFECTIVITY OF B3.13 AND D1.1 H5N1 LINEAGES IN HUMAN RESPIRATORY CULTURES. https://doi.org/10.64898/2026.08.18.745466. Abstract
submitted by kickingbird at Aug, 26, 2026 from https://doi.org/10.64898/2026.08.18.745466 (via https://www.biorxiv.org/content/10.64898/2026.08.18.745466v1)
The ongoing panzootic of clade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 viruses has reached a critical point, marked by unprecedented mammalian spillover and sustained outbreaks in U.S. dairy ... Valdez-May MJ, Perlas A, Nofrarías M, Pina-Pedrero. Transcriptomic and proteomic profiling of early blood responses reveals pathways associated with distinct clinical outcomes following H7N1 high pathogenicity avian influenza virus infection in chicken. Poult Sci. 2026 Aug 6;105(11):107527. Abstract
submitted by kickingbird at Aug, 25, 2026 from Poult Sci. 2026 Aug 6;105(11):107527 (via https://www.sciencedirect.com/science/article/pii/S003257912)
High pathogenicity avian influenza (HPAI) poses a significant threat to poultry. Some chickens show resilience to HPAI, but the mechanisms involved are poorly understood. In this study, we aimed to identify ... Yamayoshi S, Hamabata T, Inoue Y, Kiso M, Okuda M,. Characterisation of a human monoclonal antibody targeting a conserved epitope at the base of the HA head of influenza A(H3N2) virus. EBioMedicine. 2026 Aug 23;131:106450. Abstract
submitted by kickingbird at Aug, 24, 2026 from EBioMedicine. 2026 Aug 23;131:106450 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Numerous broadly reactive human monoclonal antibodies (mAbs) against the haemagglutinin (HA) of influenza A viruses have recognised conserved epitopes across HA subtypes or within subtypes. ... Sarlo Davila, K.M., Baker, A.L., Boggiatto, P.M. e. Susceptibility of calves fed unpasteurized milk from cows infected with highly pathogenic avian influenza H5N1. Nat Commun (2026). Abstract
submitted by kickingbird at Aug, 24, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-76300-1)
Highly pathogenic avian influenza (HPAI) H5N1 was confirmed in a dairy cows in Texas March 2024 and milk was identified as a critical source of virus spread within and between dairy herds. This study demonstrates ... Chen, J., Zheng, S., Qi, J. et al. Functional mapping of IFITM3 resolves its antiviral core and deciphers human influenza susceptibility. Commun Biol (2026). Abstract
submitted by kickingbird at Aug, 24, 2026 from Commun Biol (2026) (via https://link.springer.com/article/10.1038/s42003-026-10800-0)
Genetic variation in interferon-induced transmembrane protein 3 (IFITM3) contributes to inter-individual differences in influenza outcome, yet a comprehensive functional map of IFITM3 variation remains ... Kikawa C, Huddleston J, Turner SA, Loes AN, Liu J,. Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection. Virus Evol. 2026 Jul 26;12(1):veag046. Abstract
submitted by kickingbird at Aug, 24, 2026 from Virus Evol. 2026 Jul 26;12(1):veag046 (via https://academic.oup.com/ve/article/12/1/veag046/8742049)
Twice each year, a decision is made on whether to update the strains included in the seasonal influenza vaccine to better match the most recent circulating viral strains. To characterize the antigenic ... He, Y., Dong, Y., Kong, D. et al. Baculovirus-based production of virus-like particles for avian influenza: development, immunogenicity, and cross-protection against H5 and H7 AIVs. J Nanobiotechnol (2026). Abstract
submitted by kickingbird at Aug, 22, 2026 from J Nanobiotechnol (2026) (via https://link.springer.com/article/10.1186/s12951-026-04957-3)
BackgroundThe persistent threat of H5 and H7 highly pathogenic avian influenza (HPAI) necessitates effective broad-spectrum vaccines.ResultsThis study systematically evaluated the immunogenicity and protective ... 7180 items, 20/Page, Page[5/359][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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