Xu DW, Tate MD. Taking AIM at Influenza: The Role of the AIM2 Inflammasome. Viruses. 2024; 16(10):1535. Abstract
submitted by kickingbird at Oct, 22, 2024 from Viruses. 2024; 16(10):1535 (via https://www.mdpi.com/1999-4915/16/10/1535)
Influenza A viruses (IAV) are dynamic and highly mutable respiratory pathogens that present persistent public health challenges. Inflammasomes, as components of the innate immune system, play a crucial ... Galeone V, Lee C, Monaghan MT, Bauer DC, Wilson LO. Evolutionary Insights from Association Rule Mining of Co-Occurring Mutations in Influenza Hemagglutinin and Neuraminidase. Viruses. 2024; 16(10):1515. Abstract
submitted by kickingbird at Oct, 22, 2024 from Viruses. 2024; 16(10):1515 (via https://www.mdpi.com/1999-4915/16/10/1515)
Seasonal influenza viruses continuously evolve via antigenic drift. This leads to recurring epidemics, globally significant mortality rates, and the need for annually updated vaccines. Co-occurring mutations ... Hailiang Sun, etc.,al. Genetic evolution, phylodynamic and phylogeographic of H5Ny AIVs in mammals. Animals and Zoonoses. Abstract
submitted by kickingbird at Oct, 22, 2024 from Animals and Zoonoses (via https://www.sciencedirect.com/science/article/pii/S295024892)
The growing incidence of H5Ny virus infection in humans and mammals causes an increasing public health concern. To date, H5Ny virus infection in humans and mammals has been reported in 46 countries around ... Miyu Moriyama, etc.,al. [preprint]Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge. https://doi.org/10.1101/2024.10.10.616291. Abstract
submitted by kickingbird at Oct, 20, 2024 from https://doi.org/10.1101/2024.10.10.616291 (via https://www.biorxiv.org/content/10.1101/2024.10.10.616291v1)
Licensed parenteral influenza vaccines induce systemic antibody responses and alleviate disease severity but do not efficiently prevent viral entry and transmission due to the lack of local mucosal immune ... Zhang M, Zeng Y, Liu Q, Li F, Zhao J, Liu Z, Liu H. The H5N1-NS1 protein affects the host cell cycle and apoptosis through interaction with the host lncRNA PIK3CD-AS2. Virus Genes. 2024 Oct 18. Abstract
submitted by kickingbird at Oct, 20, 2024 from Virus Genes. 2024 Oct 18 (via https://link.springer.com/article/10.1007/s11262-024-02118-y)
Long noncoding RNAs (lncRNAs) are involved in the host antiviral response, but how host lncRNAs interact with viral proteins remains unclear. The NS1 protein of avian influenza viruses can affect the interferon-dependent ... Richard Webby, etc.,al. [preprint] Efficacy of oseltamivir and baloxavir against A(H5N1)-contaminated bovine milk in mice. https://doi.org/10.21203/rs.3.rs-5119512/v1. Abstract
submitted by kickingbird at Oct, 19, 2024 from https://doi.org/10.21203/rs.3.rs-5119512/v1 (via https://www.researchsquare.com/article/rs-5119512/v1)
Understanding the reliability of FDA-approved antivirals against A(H5N1) influenza viruses circulating in peridomestic species including dairy cows is critical to public health and pre-pandemic planning, ... Lisovski S, Günther A, Dewar M, Ainley D, Aldunate. Unexpected Delayed Incursion of Highly Pathogenic Avian Influenza H5N1 (Clade 2.3.4.4b) Into the Antarctic Region. Influenza Other Respir Viruses. 2024 Oct;18(10):e7. Abstract
submitted by kickingbird at Oct, 18, 2024 from Influenza Other Respir Viruses. 2024 Oct;18(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70010)
The current highly pathogenic avian influenza H5N1 panzootic is having substantial impacts on wild birds and marine mammals. Following major and widespread outbreaks in South America, an incursion to Antarctica ... Alessandro Zulli, etc.,al. [preprint]Infectivity and persistence of influenza viruses in raw milk. https://doi.org/10.1101/2024.10.10.24315269. Abstract
submitted by kickingbird at Oct, 18, 2024 from https://doi.org/10.1101/2024.10.10.24315269 (via https://www.medrxiv.org/content/10.1101/2024.10.10.24315269v)
Influenza A viruses present a significant public health risk, with recent outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in dairy cattle raising concerns about potential transmission through ... Jennifer Schrock, etc.,al. Survivability of low pathogenic avian influenza virus in aqueous poultry manure fertilizer. Journal of Applied Poultry Research, 17 Oct 2024. Abstract
submitted by kickingbird at Oct, 18, 2024 from Journal of Applied Poultry Research, 17 Oct 2024 (via https://www.sciencedirect.com/science/article/pii/S105661712)
Avian influenza has been a growing problem in the United States for decades. Low pathogenic avian influenza (LPAI) virus causes low morbidity, while highly pathogenic avian influenza (HPAI) has a devastating ... Li, R., Gao, J., Wang, L. et al. Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites. npj Viruses 2, 48 (2024). Abstract
submitted by kickingbird at Oct, 18, 2024 from npj Viruses 2, 48 (2024) (via https://www.nature.com/articles/s44298-024-00059-9)
The hemagglutinin (HA) glycoprotein of influenza virus binds host cell receptors and mediates viral entry. Here we present cryo-EM structures of fully glycosylated HAs from H5N1 and H5N8 influenza viruses. ... Song X, Tian J, Li M, Bai X, Zhao Z, Shi J, Zeng X. Epidemiology and Biological Characteristics of Influenza A (H4N6) Viruses from Wild Birds. Emerg Microbes Infect. 2024 Oct 17:2418909. Abstract
submitted by kickingbird at Oct, 18, 2024 from Emerg Microbes Infect. 2024 Oct 17:2418909 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
During the active surveillance, we isolated nine H4N6 subtype influenza A viruses from wild birds in China. To reveal the epidemiology and biology characteristics of H4 subtype influenza A virus from wild ... Wille M, Broz I, Cherrington T, Crawley A, Farrugi. Contrasting dynamics of two incursions of low-pathogenicity avian influenza virus into Australia. Virus Evol. 2024 Sep 10;10(1):veae076. Abstract
submitted by kickingbird at Oct, 18, 2024 from Virus Evol. 2024 Sep 10;10(1):veae076 (via https://academic.oup.com/ve/article/10/1/veae076/7754475)
The current panzootic of high pathogenicity avian influenza virus H5N1 demonstrates how viral incursions can have major ramifications for wildlife and domestic animals. Herein, we describe the recent incursion ... Michalska-Smith M, Clements E, Rasmussen E, Culhan. Location, Age, and Antibodies Predict Avian Influenza Virus Shedding in Ring-Billed and Franklin´s Gulls in Minnesota. Animals (Basel). 2024 Sep 26;14(19):2781. Abstract
submitted by kickingbird at Oct, 17, 2024 from Animals (Basel). 2024 Sep 26;14(19):2781 (via https://www.mdpi.com/2076-2615/14/19/2781)
Influenza A virus (IAV) is a multi-host pathogen maintained in water birds and capable of spillover into humans, wildlife, and livestock. Prior research has focused on dabbling ducks as a known IAV reservoir ... Martinez-Sobrido L, Nogales A. Recombinant Influenza A Viruses Expressing Reporter Genes from the Viral NS Segment. Int J Mol Sci. 2024 Oct 1;25(19):10584. Abstract
submitted by kickingbird at Oct, 17, 2024 from Int J Mol Sci. 2024 Oct 1;25(19):10584 (via https://www.mdpi.com/1422-0067/25/19/10584)
Studying influenza A viruses (IAVs) requires secondary experimental procedures to detect the presence of the virus in infected cells or animals. The ability to generate recombinant (r)IAV using reverse ... Baker AL, Arruda B, Palmer MV, Boggiatto P, Davila. Dairy cows inoculated with highly pathogenic avian influenza virus H5N1. Nature. 2024 Oct 15. Abstract
submitted by kickingbird at Oct, 17, 2024 from Nature. 2024 Oct 15 (via https://www.nature.com/articles/s41586-024-08166-6)
Highly pathogenic avian influenza (HPAI) H5N1 hemagglutinin clade 2.3.4.4b was detected in the United States in 2021. These HPAI viruses caused mortality events in poultry, wild birds, and wild mammals. ... Wang M, Gao Y, Shen C, Yang W, Peng Q, Cheng J, Sh. A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection. Nat Commun. 2024 Oct 15;15(1):8871. Abstract
submitted by kickingbird at Oct, 15, 2024 from Nat Commun. 2024 Oct 15;15(1):8871 (via https://www.nature.com/articles/s41467-024-53301-6)
The influenza neuraminidase (NA) is a potential target for the development of a next-generation influenza vaccine, but its antigenicity is not well understood. Here, we isolate an anti-N6 human monoclonal ... Chiba S, Kiso M, Yamada S, Someya K, Onodera Y, Ya. An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection. NPJ Vaccines. 2024 Oct 14;9(1):189. Abstract
submitted by kickingbird at Oct, 15, 2024 from NPJ Vaccines. 2024 Oct 14;9(1):189 (via https://www.nature.com/articles/s41541-024-00988-9)
Highly pathogenic avian influenza (HPAI) H5 viruses from different clades have been circulating globally, threatening wild/domestic birds and mammals. Given frequent spillovers and high mortality among ... Hsueh CS, Fasina O, Pi?eyro P, Ruden R, El-Gazzar. Histopathologic Features and Viral Antigen Distribution of H5N1 Highly Pathogenic Avian Influenza Virus Clade 2.3.4.4b from the 2022-2023 Outbreak in Iowa Wild Birds. Avian Dis. 2024 Sep;68(3):272-281. Abstract
submitted by kickingbird at Oct, 15, 2024 from Avian Dis. 2024 Sep;68(3):272-281 (via https://bioone.org/journals/avian-diseases/volume-68/issue-3)
In 2022, a new epornitic of H5N1 highly pathogenic avian influenza (HPAI) virus clade 2.3.4.4b emerged in U.S. domestic poultry with high prevalence in wild bird populations. We describe pathological findings ... Marcus Tong Zhen Wei, etc.,al. High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus. iScience. Abstract
submitted by kickingbird at Oct, 13, 2024 from iScience (via https://www.sciencedirect.com/science/article/pii/S258900422)
Diabetes mellitus significantly increases the risk of severe respiratory virus disease like influenza and COVID-19. Early evidence suggests that this susceptibility to respiratory viral disease is driven ... Joseph D. Trimarco, etc.,al. Fluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions. Virology，10 Oct 2024. Abstract
submitted by kickingbird at Oct, 12, 2024 from Virology，10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01385-24)
In early 2024, a clade 2.3.4.4b high pathogenic H5N1 avian influenza virus was detected in dairy cows and humans in the United States. Since then, it has spread to herds in at least 13 states and caused ... 6469 items, 20/Page, Page[49/324][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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