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2026-6-13 13:35:40
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Clément Fage, etc.,al. Influenza A(H1N1)pdm09 Virus Resistance to Baloxavir, Oseltamivir and Sialic Acid Mimetics in Single and Dual therapies: Insights from Human Airway Epithelia and Murine Models. Antiviral Research 2025.  Abstract  
submitted by kickingbird at May, 4, 2025 from Antiviral Research 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Influenza viruses pose a significant threat due to annual epidemics and pandemic potential. Resistance to current antivirals underscores the need for new drugs and strategies to prevent its emergence. ...

Heinz Feldmann, etc.,al. [preprint]Bovine Derived Clade 2.3.4.4b HPAI H5N1 Virus Causes Mild Disease and Limited Transmission in Pigs. https://doi.org/10.21203/rs.3.rs-6567595/v1.  Abstract  
submitted by kickingbird at May, 3, 2025 from https://doi.org/10.21203/rs.3.rs-6567595/v1 (via https://www.researchsquare.com/article/rs-6567595/v1)
Highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b emerged in dairy cows in the United States in early 2024. Since then, this clade simultaneously circulates in wild birds, cattle and ...

Carine K. Souza, etc.,al. [preprint]H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccination elicits adaptive immune responses in Holstein calves. https://doi.org/10.1101/2025.05.01.651548.  Abstract  
submitted by kickingbird at May, 3, 2025 from https://doi.org/10.1101/2025.05.01.651548 (via https://www.biorxiv.org/content/10.1101/2025.05.01.651548v2)
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4b H5N1 is circulating widely in lactating cows in the United States. Due to the critical need for intervention strategies for this outbreak, we evaluated ...

Benjamin C Mollett, etc.,al. [preprint]Diverse Genomic Landscape of Swine Influenza A Virus in England (2014 ~ 2021). https://doi.org/10.1101/2025.04.28.650978.  Abstract  
submitted by kickingbird at May, 2, 2025 from https://doi.org/10.1101/2025.04.28.650978 (via https://www.biorxiv.org/content/10.1101/2025.04.28.650978v1)
Surveillance of influenza A viruses in pigs (SwIAV) is critical for identification of novel genetic groups that pose a risk to pig health and might have zoonotic potential. SwIAVs circulating in pigs in ...

Er JC. Improving Influenza Nomenclature Based on Transmission Dynamics. Viruses. 2025; 17(5):633.  Abstract  
submitted by kickingbird at May, 1, 2025 from Viruses. 2025; 17(5):633 (via https://www.mdpi.com/1999-4915/17/5/633)
Influenza A viruses (IAVs) evolve rapidly, exhibit zoonotic potential, and frequently adapt to new hosts, often establishing long-term reservoirs. Despite advancements in genetic sequencing and phylogenetic ...

Ruiz S, Díaz-Gavidia C, González MA, Galdames P, O. Circulation and Spillover of pdmH1N1 Influenza A Virus at an Educational Swine Farm in Chile, 2019–2023. Viruses 2025; 17, no. 5: 635.  Abstract  
submitted by kickingbird at May, 1, 2025 from Viruses 2025; 17, no. 5: 635 (via https://www.mdpi.com/1999-4915/17/5/635)
Educational farms provide students with hands-on experience in agricultural and animal practices. However, the close contact between humans and farm animals creates a significant interface for zoonotic ...

Perera, T., Bowatte, A., Perera, S. et al. Molecular and phylogenetic analysis of influenza A and B viruses circulating in Sri Lanka following the COVID-19 pandemic. Virus Genes (2025).  Abstract  
submitted by kickingbird at May, 1, 2025 from Virus Genes (2025) (via https://link.springer.com/article/10.1007/s11262-025-02161-3)
Influenza viruses pose significant public health challenges, causing seasonal epidemics with high morbidity and mortality. This study sequenced influenza viral RNA from hospitalized patients with severe ...

Gorin S, Richard G, Quéguiner S, Chastagner A, Bar. Pathogenesis, Transmission, and Within-Host Evolution of Bovine-Origin Influenza D Virus in Pigs. Transbound Emerg Dis. 2024 May 14;2024:9009051.  Abstract  
submitted by kickingbird at May, 1, 2025 from Transbound Emerg Dis. 2024 May 14;2024:9009051 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/9009051)
Whereas bovine has been demonstrated as the main reservoir of influenza D virus (IDV), this virus was first isolated in a pig and is regularly detected in some swine populations. However, the role of swine ...

Harrington WN, Turner JCM, Barman S, Feeroz MM, Ha. Longitudinal Active Avian Influenza Surveillance in Bangladesh From 2017-2022 Reveals Differential IAV and H5 Infection and Viral Burden Associated With Bird Species, Sex, and Age. Transbound Emerg Dis. 2024 Dec 13;2024:5569836.  Abstract  
submitted by kickingbird at May, 1, 2025 from Transbound Emerg Dis. 2024 Dec 13;2024:5569836 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/5569836)
Influenza viruses are a major global health burden with up to 650,000 associated deaths annually. Beyond seasonal illness, influenza A viruses (IAVs) pose a constant pandemic threat due to novel emergent ...

Goraichuk IV, Suarez DL. Custom barcoded primers for influenza A nanopore sequencing: enhanced performance with reduced preparation time. Front. Cell. Infect. Microbiol. 15:1545032.  Abstract  
submitted by kickingbird at May, 1, 2025 from Front. Cell. Infect. Microbiol. 15:1545032 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Highly pathogenic avian influenza is endemic and widespread in wild birds and is causing major outbreaks in poultry worldwide and in U.S. dairy cows, with several recent human cases, highlighting the need ...

Christopher A Gonelli, etc.,al. [preprint]Memory T and B cells with recognition of avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines. https://doi.org/10.1101/2025.04.28.651131.  Abstract  
submitted by kickingbird at Apr, 30, 2025 from https://doi.org/10.1101/2025.04.28.651131 (via https://www.biorxiv.org/content/10.1101/2025.04.28.651131v1)
Immunisation remains the most cost-effective mechanism to combat global influenza infection and is widely employed against seasonal influenza viruses. Zoonotic transmission of avian influenza A viruses ...

Ramesh, A.K., Sivaccumar, J.P., Ye, X. et al. An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses. Nat Commun 16, 4025 (2025).  Abstract  
submitted by kickingbird at Apr, 30, 2025 from Nat Commun 16, 4025 (2025) (via https://www.nature.com/articles/s41467-025-59294-0)
Engineering broadly neutralizing monoclonal antibodies (mAbs) targeting the hemagglutinin (HA) of Influenza A virus (IAV) is a promising approach for intervention of seasonal flu. However, HA plasticity ...

Mahmoud, S.H., Gomaa, M., El Taweel, A. et al. Transmission dynamics of avian influenza viruses in Egyptian poultry markets. npj Viruses 2, 25 (2024).  Abstract  
submitted by kickingbird at Apr, 30, 2025 from npj Viruses 2, 25 (2024) (via https://www.nature.com/articles/s44298-024-00035-3)
Live bird markets (LBMs) are considered hotspots for Avian Influenza Viruses (AIVs). In such markets, AIVs pose threats to both poultry and public health. Within LBMs, AIVs spread through various routes, ...

Takada, K., Kida, Y., Watanabe, S. et al. Influenza B viruses are more susceptible to high temperatures than influenza A viruses. npj Viruses 2, 65 (2024).  Abstract  
submitted by kickingbird at Apr, 30, 2025 from npj Viruses 2, 65 (2024) (via https://www.nature.com/articles/s44298-024-00077-7)
Seasonal influenza is caused by two subtypes of influenza A virus (A/H1N1 and A/H3N2) and two lineages of influenza B viruses (B/Victoria-lineage and B/Yamagata-lineage). Seasonal influenza viruses replicate ...

Kasianov N, Sharshov K, Derko A, Sobolev I, Dubovi. Exploring Avian Influenza Viruses in Yakutia - The Largest Breeding Habitat of Wild Migratory Birds in Northeastern Siberia. Viruses. 2025; 17(5):632.  Abstract  
submitted by kickingbird at Apr, 29, 2025 from Viruses. 2025; 17(5):632 (via https://www.mdpi.com/1999-4915/17/5/632)
Yakutia, the largest breeding ground for wild migratory birds in Northeastern Siberia, plays a big role in the global ecology of avian influenza viruses (AIVs). In this study, we present the results of ...

Sun, Hailiang et al. Genome-scale evolution and phylodynamics of swine influenza A viruses in China: a genomic epidemiology study. The Lancet Microbe.  Abstract  
submitted by kickingbird at Apr, 29, 2025 from The Lancet Microbe (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
BackgroundPigs are recognised as crucial intermediate hosts for the emergence of influenza viruses of pandemic potential. As the largest pork-producing nation, China hosts a complex ecosystem of swine ...

Xiaojian Zhang, Hua Shi, Ted M. Ross. Multivalent H3 COBRA-based influenza vaccine elicits enhanced immune response in a pre-immune elderly ferret model. Vaccine, 2025.  Abstract  
submitted by kickingbird at Apr, 28, 2025 from Vaccine, 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Influenza viruses cause significant mortality in humans, especially among people 65 years and older. The outbreaks of A(H3N2) influenza viruses or viruses of vaccine-mismatched strains are usually associated ...

Matteo Iervolino, etc.,al. [preprint]The expanding avian influenza panzootic: skua die-off in Antarctica. https://doi.org/10.1101/2025.04.25.650384.  Abstract  
submitted by kickingbird at Apr, 28, 2025 from https://doi.org/10.1101/2025.04.25.650384 (via https://www.biorxiv.org/content/10.1101/2025.04.25.650384v1)
High pathogenicity avian influenza virus of subtype H5 (H5 HPAIV), clade 2.3.4.4b, invaded Antarctica in 2023. Here we show that H5 HPAIV caused high mortality in a breeding colony of skuas at one of ten ...

L. Martelli, etc.,al. Exploring the Role of Wild Bird Species in the Transmission of Avian Influenza to Poultry. Transboundary and Emerging Diseases, 2025, 2288535.  Abstract  
submitted by kickingbird at Apr, 28, 2025 from Transboundary and Emerging Diseases, 2025, 2288535 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/2288535)
Wild aquatic birds are crucial in maintaining the high pathogenicity avian influenza (HPAI) viruses. However, the HPAI dynamic at the wild-domestic interface is still poorly known, and a comprehensive ...

Christopher Neil Davis, etc.,al. [preprint]A modelling assessment for the impact of control measures on highly pathogenic avian influenza transmission in poultry in Great Britain. https://doi.org/10.1101/2025.04.24.650264.  Abstract  
submitted by kickingbird at Apr, 28, 2025 from https://doi.org/10.1101/2025.04.24.650264 (via https://www.biorxiv.org/content/10.1101/2025.04.24.650264v1)
Since 2020, large-scale outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in Great Britain have resulted in substantial poultry mortality and economic losses. Alongside the costs, the risk of ...

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