Yong Zhou, etc.,al. Origin, spread, and interspecies transmission of a dominant genotype of BJ/94 lineage H9N2 avian influenza viruses with increased threat. Virus Evolution, veae106. Abstract
submitted by kickingbird at Dec, 11, 2024 from Virus Evolution, veae106 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The H9N2 subtype of avian influenza viruses (AIVs) is widely prevalent in poultry and wild birds globally, with occasional transmission to humans. In comparison to other H9N2 lineages, the BJ/94 lineage ... Feng Wen, etc.,al. Novel human-type receptor-binding H5N1 virus in live poultry markets, China. The Lancet Microbe. Abstract
submitted by kickingbird at Dec, 11, 2024 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
Avian influenza viruses represent a considerable public health risk, with the capability to cross species barriers and cause severe disease in humans. The emergence of H5N1 subtype of highly pathogenic ... Ankerhold J, Kessler S, Beer M, Schwemmle M, Cimin. Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024. Emerg Infect Dis. 2025 Jan. Abstract
submitted by kickingbird at Dec, 11, 2024 from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1236_article)
We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and in MxA-transgenic mice. However, H5N1 ... Sarsenov R, Babenko D, Kamalova D, Amirgazin A, Be. Complete genome sequence of a human influenza a virus (H1N1) detected in Kazakhstan in the fall of 2022. Microbiol Resour Announc. 2024 Dec 10:e0104024. Abstract
submitted by kickingbird at Dec, 11, 2024 from Microbiol Resour Announc. 2024 Dec 10:e0104024 (via https://journals.asm.org/doi/10.1128/mra.01040-24)
An Orthomyxoviridae Alphainfluenza virus Influenza A virus strain, A/Kazakhstan/Flu-H11-6/2022(H1N1), was isolated in Karaganda, Central Kazakhstan during a study of acute respiratory infections among ... Yin Y, Kan X, Miao X, Sun Y, Chen S, Qin T, Ding C. H5 subtype avian influenza virus induces Golgi apparatus stress response via TFE3 pathway to promote virus replication. PLoS Pathog. 2024 Dec 9;20(12):e1012748. Abstract
submitted by kickingbird at Dec, 10, 2024 from PLoS Pathog. 2024 Dec 9;20(12):e1012748 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During infection, avian influenza virus (AIV) triggers endoplasmic reticulum (ER) stress, a well-established phenomenon in previous research. The Golgi apparatus, situated downstream of the ER and crucial ... Xia M, Huang P, Vago FS, Jiang W, Tan M. Pseudovirus nanoparticles targeting the receptor binding HA1 domains of influenza viruses elicited high HA1-specific antibody responses and protected mice against mortality caused by influenza virus c. Vaccine. 2024 Dec 7:126585. Abstract
submitted by kickingbird at Dec, 9, 2024 from Vaccine. 2024 Dec 7:126585 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The continually high disease burden of influenza and the relatively low effectiveness of current influenza vaccines call for enhanced vaccine strategies. We previously generated unique S-HA1 pseudovirus ... Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilb. Marked Neurotropism and Potential Adaptation of H5N1 Clade 2.3.4.4.b Virus in Naturally Infected Domestic Cats. Emerg Microbes Infect. 2024 Dec 9:2440498. Abstract
submitted by kickingbird at Dec, 9, 2024 from Emerg Microbes Infect. 2024 Dec 9:2440498 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. ... Gunasekara E, Hair-Bejo M, Aini I, Omar AR. Molecular characterisation of novel reassortants of the G57 genotype of low-pathogenic avian influenza H9N2 virus isolated from poultry farms in Malaysia. Arch Virol. 2024 Dec 7;170(1):3. Abstract
submitted by kickingbird at Dec, 8, 2024 from Arch Virol. 2024 Dec 7;170(1):3 (via https://link.springer.com/article/10.1007/s00705-024-06159-4)
In late 2017, Malaysia reported repeated outbreaks of low-pathogenic avian influenza virus (LPAI) H9N2 infections in commercial poultry flocks. Two H9N2 viruses, A/chicken/Malaysia/Negeri Sembilan/UPM994/2018 ... Isabela Carvalho Brcko, etc.,al. Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis. Virus Evolution, veae102. Abstract
submitted by kickingbird at Dec, 7, 2024 from Virus Evolution, veae102 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Influenza A and B viruses represent significant global health threats, contributing substantially to morbidity and mortality rates. However, a comprehensive understanding of the molecular epidemiology ... Jiawei Luo, etc.,al. The PB1 protein of H9N2 influenza A virus inhibits antiviral innate immunity by targeting MAVS for TRIM25-mediated autophagic degradation. Poultry Science. Abstract
submitted by kickingbird at Dec, 7, 2024 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. However, the regulatory mechanisms remain not fully understood. ... Nuo Xu, etc.,al. The evolution of hemagglutinin-158 and neuraminidase-88 glycosylation sites modulates antigenicity and pathogenicity of clade 2.3.2.1 H5N1 avian influenza viruses. Veterinary Microbiology. Abstract
submitted by kickingbird at Dec, 7, 2024 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Clade 2.3.2.1 of the H5N1 avian influenza virus (AIV) evolved into several subclades. However, the effect of glycosylation on the biological characteristics of hemagglutinin (HA) and/or neuraminidase (NA) ... Matthew L Turnbull, etc.,al. [preprint]POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS. https://doi.org/10.1101/2024.11.29.626120. Abstract
submitted by kickingbird at Dec, 6, 2024 from https://doi.org/10.1101/2024.11.29.626120 (via https://www.biorxiv.org/content/10.1101/2024.11.29.626120v1)
H5N1 avian influenza virus (lineage 2.3.4.4b, B3.13 genotype) has caused, unexpectedly, a large outbreak in dairy cattle in North America. It is critical to ascertain how this virus has specifically adapted ... Lv H, Teo QW, Lee C-CD, Liang W, Choi D, Mao KJ, A. Differential antigenic imprinting effects between influenza H1N1 hemagglutinin and neuraminidase in a mouse model. J Virol. 2024 Dec 5:e0169524. Abstract
submitted by kickingbird at Dec, 6, 2024 from J Virol. 2024 Dec 5:e0169524 (via https://journals.asm.org/doi/10.1128/jvi.01695-24)
Understanding how immune history influences influenza immunity is essential for developing effective vaccines and therapeutic strategies. This study examines the antigenic imprinting of influenza hemagglutinin ... Lin TH, Zhu X, Wang S, Zhang D, McBride R, Yu W, B. A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors. Science. 2024 Dec 6;386(6726):1128-1134. Abstract
submitted by kickingbird at Dec, 6, 2024 from Science. 2024 Dec 6;386(6726):1128-1134 (via https://www.science.org/doi/10.1126/science.adt0180)
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-human ... Yang K, Nizami S, Hu S, Zou L, Deng H, Xie J, Guo. Genetic diversity of highly pathogenic avian influenza H5N6 and H5N8 viruses in poultry markets in Guangdong, China, 2020~2022. J Virol. 2024 Dec 4:e0114524. Abstract
submitted by kickingbird at Dec, 5, 2024 from J Virol. 2024 Dec 4:e0114524 (via https://journals.asm.org/doi/10.1128/jvi.01145-24)
H5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and wild birds, with sporadic spillover infections ... Tosheva II, Filaire F, Rijnink WF, de Meulder D, v. Influenza A(H5N1) shedding in air corresponds to transmissibility in mammals. Nat Microbiol. 2024 Dec 2. Abstract
submitted by kickingbird at Dec, 4, 2024 from Nat Microbiol. 2024 Dec 2 (via https://www.nature.com/articles/s41564-024-01885-6)
An increase in spillover events of highly pathogenic avian influenza A(H5N1) viruses to mammals suggests selection of viruses that transmit well in mammals. Here we use air-sampling devices to continuously ... Guilfoyle K, Mirolo M, van Amerongen G, van der Ne. Susceptibility of calf lung slice cultures to H5N1 influenza virus. Emerg Microbes Infect. 2024 Dec 3:2432368. Abstract
submitted by kickingbird at Dec, 4, 2024 from Emerg Microbes Infect. 2024 Dec 3:2432368 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging ... Deng Y-M, Wille M, Dapat C, Xie R, Lay O, Peck H,. Influenza A(H5N1) Virus Clade 2.3.2.1a in Traveler Returning to Australia from India, 2024. Emerg Infect Dis. 2025 Jan. Abstract
submitted by kickingbird at Dec, 4, 2024 from Emerg Infect Dis. 2025 Jan (via https://wwwnc.cdc.gov/eid/article/31/1/24-1210_article)
We report highly pathogenic avian influenza A(H5N1) virus clade 2.3.2.1a in a child traveler returning to Australia from India. The virus was a previously unreported reassortant consisting of clade 2.3.2.1a, ... Li L, Xu J, Yuan J, Zhang R, Xu T. TRPM2 deficiency ameliorated H9N2 influenza virus-induced acute lung injury in mice. Microb Pathog. 2024 Nov 28:107183. Abstract
submitted by kickingbird at Dec, 2, 2024 from Microb Pathog. 2024 Nov 28:107183 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Oxidative stress is involved in lung damage induced by the influenza virus. The transient receptor potential melastatin-2 (TRPM2) cation channel, a Ca2+ permeable non-selective cation channel, is implicated ... Lisa Bauer, etc.,al. [preprint]A 2022 avian H5N1 influenza A virus from clade 2.3.4.4b attaches to and replicates better in human respiratory epithelium than a 2005 H5N1 virus from clade 2.3.2.1. https://doi.org/10.1101/2024.11.27.625596. Abstract
submitted by kickingbird at Nov, 29, 2024 from https://doi.org/10.1101/2024.11.27.625596 (via https://www.biorxiv.org/content/10.1101/2024.11.27.625596v1)
Background: Highly pathogenic avian influenza (HPAI) H5 viruses of the A/Goose/Guangdong/1/1996 (GsGd) lineage pose significant global risks to wildlife, domestic animals, and humans. Recent cross-species ... 6469 items, 20/Page, Page[44/324][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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