Lin-Lei Chen, etc.,al. [preprint]Risk assessment of 2024 cattle H5N1 using age-stratified serosurveillance data. https://doi.org/10.1101/2024.12.23.24319580. Abstract
submitted by kickingbird at Jan, 1, 2025 from https://doi.org/10.1101/2024.12.23.24319580 (via https://www.medrxiv.org/content/10.1101/2024.12.23.24319580v)
The highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b has caused a human outbreak in North America since March 2024. Here, we conducted a serosurveillance study to determine the risk of A(H5N1) ... Resende PC, Junqueira DM, Tochetto C, Ogrzewalska. Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023. Nat Commun. 2024 Dec 30;15(1):10748. Abstract
submitted by kickingbird at Jan, 1, 2025 from Nat Commun. 2024 Dec 30;15(1):10748 (via https://www.nature.com/articles/s41467-024-53815-z)
Zoonotic infections (swine-human) caused by influenza A viruses (IAVs) have been reported and linked to close contact between these species. Here, we describe eight human IAV variant infections (6 mild ... Sun L, Guo X, Yu M, Wang XF, Ren H, Wang X. Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction. Nat Commun. 2024 Dec 30;15(1):10805. Abstract
submitted by kickingbird at Jan, 1, 2025 from Nat Commun. 2024 Dec 30;15(1):10805 (via https://www.nature.com/articles/s41467-024-55034-y)
Human ANP32A/B (huANP32A/B) poorly support the polymerase activity of avian influenza viruses (AIVs), thereby limiting interspecies transmission of AIVs from birds to humans. The SUMO-interacting motif ... Good, M.R., Fernández-Quintero, M.L., Ji, W. et al. A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth. Nat Commun 15, 10768 (2024). Abstract
submitted by kickingbird at Dec, 31, 2024 from Nat Commun 15, 10768 (2024) (via https://www.nature.com/articles/s41467-024-54934-3)
Clade 2.3.4.4b H5N1 is causing an unprecedented outbreak in dairy cows in the United States. To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin ... Daniel Higgins, etc.,al. [preprint]Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humans. https://doi.org/10.1101/2024.09.01.24312235. Abstract
submitted by kickingbird at Dec, 30, 2024 from https://doi.org/10.1101/2024.09.01.24312235 (via https://www.medrxiv.org/content/10.1101/2024.09.01.24312235v)
Avian influenza A(H5N1) poses a public health risk due to its pandemic potential should the virus mutate to become human-to-human transmissible. To date, reported influenza A(H5N1) human cases have typically ... Chen X, Kong M, Ma C, Zhang M, Hu Z, Gu M, Wang X,. The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens. Virulence. 2025 Dec;16(1):2445238. Abstract
submitted by kickingbird at Dec, 30, 2024 from Virulence. 2025 Dec;16(1):2445238 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2024.2)
Several viruses, including influenza A virus (IAV), encode viral factors to hijack cellular RNA biogenesis processes to direct the degradation of host mRNAs, termed "host shutoff." Host shutoff enables ... Jaemoo Kim, etc.,al. A low pathogenic avian influenza A/Mallard/South Korea/KNU2019-34/2019 (H1N1) virus has the potential to increase the mammalian pathogenicity. Virologica Sinica. Abstract
submitted by kickingbird at Dec, 30, 2024 from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza, a highly contagious respiratory infectious disease caused by an influenza virus, is a threat to public health worldwide. Avian influenza viruses (AIVs) have the potential to cause the next pandemic ... Mostafa A, Barre RS, Allué-Guardia A, Escobedo RA,. Replication Kinetics, Pathogenicity and Virus-induced Cellular Responses of Cattle-origin Influenza A(H5N1) isolates from Texas, United States. Emerg Microbes Infect. 2024 Dec 27:2447614. Abstract
submitted by kickingbird at Dec, 28, 2024 from Emerg Microbes Infect. 2024 Dec 27:2447614 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States (US). Shortly after, human H5N1 infection was reported in a dairy worker in Texas ... He L, Zhang Y, Si K, Yu C, Shang K, Yu Z, Wei Y, D. Evidence of an emerging triple-reassortant H3N3 avian influenza virus in China. BMC Genomics. 2024 Dec 26;25(1):1249. Abstract
submitted by kickingbird at Dec, 27, 2024 from BMC Genomics. 2024 Dec 26;25(1):1249 (via https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286)
The H3 subtype of avian influenza virus (AIV) stands out as one of the most prevalent subtypes, posing a significant threat to public health. In this study, a novel triple-reassortant H3N3 AIV designated ... Ando H, Murakami M, Kitajima M, Reynolds KA. Wastewater-based estimation of temporal variation in shedding amount of influenza A virus and clinically identified cases using the PRESENS model. Environ Int. 2024 Dec 19;195:109218. Abstract
submitted by kickingbird at Dec, 25, 2024 from Environ Int. 2024 Dec 19;195:109218 (via https://www.sciencedirect.com/science/article/pii/S016041202)
Wastewater-based estimation of infectious disease prevalence in real-time assists public health authorities in developing effective responses to current outbreaks. However, wastewater-based estimation ... Xuyong Li, etc.,al. Novel H16N3 avian influenza viruses isolated from migratory gulls in China in 2023. Front. Microbiol. Volume 15 - 2024. Abstract
submitted by kickingbird at Dec, 25, 2024 from Front. Microbiol. Volume 15 - 2024 (via https://www.frontiersin.org/journals/microbiology/articles/1)
As a rare subtype of avian influenza virus, H16 viruses are predominant in gulls but rarely found in domestic birds. The low prevalence of H16 viruses has limited our understanding of their epidemiology ... Fumiya Kozawa, etc.,al. [preprint]The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection. https://doi.org/10.1101/2024.12.20.629723. Abstract
submitted by kickingbird at Dec, 24, 2024 from https://doi.org/10.1101/2024.12.20.629723 (via https://www.biorxiv.org/content/10.1101/2024.12.20.629723v1)
Influenza A viruses (IAVs) initially infect a few host cells, and the infection subsequently spreads to neighboring cells. However, the molecular mechanisms underlying this expansion remain unclear. Here, ... Sidney J, Kim A-R, de Vries RD, Peters B, Meade PS. Targets of influenza human T-cell response are mostly conserved in H5N1. mBio. 2024 Dec 26:e0347924. Abstract
submitted by kickingbird at Dec, 24, 2024 from mBio. 2024 Dec 26:e0347924 (via https://journals.asm.org/doi/10.1128/mbio.03479-24)
Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns ... Niedringhaus KD, Chan TC, McDowell A, Maxwell L, S. Surveillance of Highly Pathogenic Avian Influenza Virus in Wild Canids from Pennsylvania, USA. Animals. 2024; 14(24):3700. Abstract
submitted by kickingbird at Dec, 23, 2024 from Animals. 2024; 14(24):3700 (via https://www.mdpi.com/2076-2615/14/24/3700)
The avian influenza virus is a global pathogen with significant health and economic implications. While primarily a pathogen of wild and domestic birds, recent outbreaks of the H5N1 highly pathogenic avian ... Ishraq Rahman, etc.,al. Recurring incursions and dissemination of novel Eurasian-origin H5Nx avian influenza viruses in Atlantic Canada. Virus Evolution, veae111. Abstract
submitted by kickingbird at Dec, 22, 2024 from Virus Evolution, veae111 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
Wild birds are important hosts of influenza A viruses (IAVs) and play an important role in their ecology. The emergence of the A/goose/Guangdong/1/1996 H5N1 (Gs/GD) lineage marked a shift in IAV ecology, ... Lambodhar Damodaran, Anna Jaeger, Louise H Moncla. [preprint]Intensive transmission in wild, migratory birds drove rapid geographic dissemination and repeated spillovers of H5N1 into agriculture in North America. https://doi.org/10.1101/2024.12.16.628739. Abstract
submitted by kickingbird at Dec, 22, 2024 from https://doi.org/10.1101/2024.12.16.628739 (via https://www.biorxiv.org/content/10.1101/2024.12.16.628739v1)
Since late 2021, a panzootic of highly pathogenic H5N1 avian influenza virus has driven significant morbidity and mortality in wild birds, domestic poultry, and mammals. In North America, infections in ... Chen W, Lu S, Xiong H, Xiang Z, Wang Y, Hu J, Pan. Gene flow and its sporadic spillover: H10 and N5 avian influenza viruses from wild birds and the H10N5 human cases in China. Virol Sin. 2024 Dec 18:S1995-820X(24)00198-6. Abstract
submitted by kickingbird at Dec, 22, 2024 from Virol Sin. 2024 Dec 18:S1995-820X(24)00198-6 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
On 30 January 2024, China announced the first human case of H10N5 influenza infection. Prior to this, human cases of H10N7 and H10N8 had been reported. It is now appropriate to re-examine the evolution ... Yan Zhou, etc.,al. [preprint]Highly pathogenic avian influenza virus H5N1 infection in dairy cows confers protective immunity against reinfection. https://doi.org/10.21203/rs.3.rs-5613077/v1. Abstract
submitted by kickingbird at Dec, 21, 2024 from https://doi.org/10.21203/rs.3.rs-5613077/v1 (via https://www.researchsquare.com/article/rs-5613077/v1)
An unprecedented spillover of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b to dairy cows in March 2024 has affected over 700 US dairy herds in addition to spillback to commercial poultry ... Zhao L, Tian M, Hu X, Fan M, Hou C, Ping J. PB2 627V and HA 217 sites synergistically affect the lethality of H9N2 in mice. Virol Sin. 2024 Dec 17:S1995-820X(24)00199-8. Abstract
submitted by kickingbird at Dec, 21, 2024 from Virol Sin. 2024 Dec 17:S1995-820X(24)00199-8 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
The H9N2 subtype avian influenza virus (AIV) continues to propagate and undergo evolution within China, thereby posing a significant threat to the poultry industry. This study encompassed the collection ... Zhao B, Sun Z, Wang S, Shi Z, Jiang Y, Wang X, Den. Structural basis of different neutralization capabilities of monoclonal antibodies against H7N9 virus. J Virol. 2024 Dec 20:e0140024. Abstract
submitted by kickingbird at Dec, 21, 2024 from J Virol. 2024 Dec 20:e0140024 (via https://journals.asm.org/doi/10.1128/jvi.01400-24)
Neutralizing antibodies (nAbs) are important for the treatment of emerging viral diseases and for effective vaccine development. In this study, we generated and evaluated three nAbs (1H9, 2D7, and C4H4) ... 6469 items, 20/Page, Page[42/324][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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