Zhou J, Hemmink JD, Whittaker CJ, Shelton HA, Peac. Animal Models in Influenza Research. Methods Mol Biol. 2025;2890:53-88. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:53-88 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Animal model systems for human and animal influenza virus infection and transmission have been established to address research questions which cannot be addressed using in vitro models. Several animal ... Broich L, Fu Y, Sieben C. Live-Cell Single-Molecule Imaging of Influenza A Virus-Receptor Interaction. Methods Mol Biol. 2025;2890:89-101. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:89-101 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A viruses are a major health care burden, and their biology has been intensely studied for decades. However, many details of virus infection are still elusive, requiring the development of refined ... Pathak T, Gupta K, Kumar N, Banerjee I. Monitoring Influenza A Virus Entry Using Quantitative Fluorescence Microscopy. Methods Mol Biol. 2025;2890:103-123. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:103-123 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) is a major threat to global human health and is a topic of intense research. With the continuous problem of seasonal influenza and the threat of potential pandemics due to frequent ... Nakano M, Noda T. Purification and Ultramicroscopic Observation of the Influenza A Virus Ribonucleoprotein Complex. Methods Mol Biol. 2025;2890:141-149. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:141-149 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) has an eight-segmented, single-stranded, negative-sense viral genomic RNA (vRNA). Each vRNA strand associates with nucleoproteins and an RNA-dependent RNA polymerase complex to ... Peterl S, Wachsmuth-Melm M, Chlanda P. Sample Preparation for Cryo-Electron Tomography of Influenza A Virus and Infected Cells. Methods Mol Biol. 2025;2890:169-184. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:169-184 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) replication within host cells relies on tightly controlled, dynamic interactions between viral and cellular components. Yet we have a limited understanding of the viral replication ... Sousa AL, Tranfield EM. Room Temperature Transmission Electron Microscopy of Influenza A Virus Samples. Methods Mol Biol. 2025;2890:151-167. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:151-167 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Transmission electron microscopy is an imaging technique that visualizes the ultrastructure of samples, revealing not just the structures of interest but also the context occurring around the structures ... Lee N. Mapping Binding Sites of Nucleoprotein Within the Influenza Virus RNA Genome. Methods Mol Biol. 2025;2890:211-224. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:211-224 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
With the advent of next-generation sequencing, a plethora of techniques have been developed to uncover nucleic acid interactions with unprecedented resolution. For example, UV-crosslinking and immunoprecipitation ... Cha RM, Park MJ, Baek YG, Lee YN, Jang Y, Kang YM,. Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022-2023. Virus Res. 2025 Jan 31:199541. Abstract
submitted by kickingbird at Feb, 3, 2025 from Virus Res. 2025 Jan 31:199541 (via https://pubmed.ncbi.nlm.nih.gov/39894372/)
During the 2022-2023 winter season in South Korea, a novel clade 2.3.4.4b H5N1 HPAIV was first detected in wild birds, which then subsequently caused multiple outbreaks in poultry farms and wild birds. ... Kirkpatrick Roubidoux E, Meliopoulos V, Livingston. Intraductal infection with H5N1 clade 2.3.4.4b influenza virus. J Virol. 2025 Jan 31:e0192724. Abstract
submitted by kickingbird at Feb, 1, 2025 from J Virol. 2025 Jan 31:e0192724 (via https://journals.asm.org/doi/10.1128/jvi.01927-24)
In March 2024, highly pathogenic avian influenza (HPAI) H5N1 of the clade 2.3.4.4b was detected in dairy cows in Texas and has since been detected in several other U.S. states. Virus has been detected ... Beate M. Crossley, etc.,al. In laboratory inactivation of H5N1 in raw whole milk through milk acidification: results from a pilot study. Journal of Dairy Science. Abstract
submitted by kickingbird at Jan, 30, 2025 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
Avian Influenza virus H5N1 2.3.4.4.b has recently been detected in cattle, with milk from infected animals reported to contain a high viral load, serving as a potential source for shedding and dissemination ... Nicholas C. Morano, etc.,al. Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Highly pathogenic avian influenza has spilled into many mammals, most notably cows and poultry, with several dozen human breakthrough infections. Zoonotic crossovers, with hemagglutinins mutated to enhance ... Huarui Duan, etc.,al. Computational design and improvement of a broad influenza virus HA stem targeting antibody. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Broadly neutralizing antibodies (nAbs) are vital therapeutic tools to counteract both pandemic and seasonal influenza threats. Traditional strategies for optimizing nAbs generally rely on labor-intensive, ... Nishiyama A, Nogimori T, Masuta Y, Matsuura T, Kas. Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination. Vaccines. 2025; 13(2):140. Abstract
submitted by kickingbird at Jan, 30, 2025 from Vaccines. 2025; 13(2):140 (via https://www.mdpi.com/2076-393X/13/2/140)
Background: Current influenza A vaccines primarily induce neutralizing antibodies targeting the variable hemagglutinin (HA) head domain, limiting their effectiveness against diverse or emerging influenza ... Thomas Rawson, etc.,al. [preprint]A mathematical model of H5N1 influenza transmission in US dairy cattle.. https://doi.org/10.1101/2025.01.28.25321250. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.1101/2025.01.28.25321250 (via https://www.medrxiv.org/content/10.1101/2025.01.28.25321250v)
We present a stochastic metapopulation transmission model that simulates the spread of H5N1 avian influenza through individual dairy cows in 35,974 dairy herds in the continental United States. Transmission ... Zhang L, Yang Q, Shao Y, Ding S, Guo J, Gao GF, De. Influenza A virus NS2 protein acts on vRNA-resident polymerase to drive the transcription to replication switch. Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027. Abstract
submitted by kickingbird at Jan, 30, 2025 from Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027 (via https://academic.oup.com/nar/article/53/3/gkaf027/7986046)
The heterotrimeric RNA-dependent RNA polymerase (RdRp) of influenza A virus catalyzes viral RNA transcription (vRNA→mRNA) and replication (vRNA→cRNA→vRNA) by adopting different conformations. A switch ... Jie Hu, Yuting Xu, Min Ma, Chenyao Zhao, Yue Yuan,. Novel Reassortant Avian Influenza A(H9N2) Viruses in Wild Birds in Shanghai, China, 2020–2023. Poultry Science. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus poses significant challenges to global poultry and human health. During the active surveillance of avian influenza virus in wild birds in Shanghai from 2020 to ... Yan M, Ma T, Shi X, Chen Q, Li L, Xu B, Pan X, Ten. Isolation and Characterization of H1 Subtype Swine Influenza Viruses Recently Circulating in China. Viruses. 2025; 17(2):185. Abstract
submitted by kickingbird at Jan, 28, 2025 from Viruses. 2025; 17(2):185 (via https://www.mdpi.com/1999-4915/17/2/185)
Pigs serve as a mixing vessel for influenza viruses and can independently promote the emergence of pandemic strains in humans. During our surveillance of pig populations from 2021 to 2023 in China, 11 ... Figueroa T, Bessière P, Coggon A, Bouwman KM, van. The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in Ducks. J Virol. 2020 May 4;94(10):e00289-20. Abstract
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2020 May 4;94(10):e00289-20 (via https://journals.asm.org/doi/10.1128/jvi.00289-20)
Ducks usually show little or no clinical signs following highly pathogenic avian influenza virus infection. In order to analyze whether the microbiota could contribute to the control of influenza virus ... Yuk SS, To EO, Kwon JH, Noh JY, Hong WT, Jeong JH,. Optimization of inactivated H5N9 highly pathogenic avian influenza vaccine and inactivated Salmonella enterica serovar Typhimurium vaccine with antigen dose and prime-boost regimen in domestic ducks. Poult Sci. 2017 Sep 1;96(9):3079-3085. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poult Sci. 2017 Sep 1;96(9):3079-3085 (via https://www.sciencedirect.com/science/article/pii/S003257911)
Owing to the increase in the number of diseases affecting ducks and the demand for food safety by consumers, vaccination has become one of the factors that influence duck meat productivity. The highly ... Smith S, Rayner JO, Kim JH. Fluorofurimazine, a novel NanoLuc substrate, enhances real-time tracking of influenza A virus infection without altering pathogenicity in mice. Microbiol Spectr. 2025 Jan 27:e0268924. Abstract
submitted by kickingbird at Jan, 28, 2025 from Microbiol Spectr. 2025 Jan 27:e0268924 (via https://journals.asm.org/doi/10.1128/spectrum.02689-24)
Bioluminescence imaging (BLI) using engineered bioluminescent viruses has emerged as a powerful tool for real-time, noninvasive monitoring of viral replication in living animals. While traditional luciferase-based ... 6469 items, 20/Page, Page[38/324][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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