Wang, P., Fu, J., Cheng, L. et al. Neutralizing monoclonal antibodies as effective therapeutics and prophylactics against lethal H10N7 avian influenza infection in a mouse model. Vet Res 56, 75 (2025). Abstract
submitted by kickingbird at Apr, 7, 2025 from Vet Res 56, 75 (2025) (via https://link.springer.com/article/10.1186/s13567-025-01504-0)
The H10 subtype of avian influenza virus (AIV) is widespread in poultry worldwide and poses a significant threat to animal health. With the emergence of sporadic and fatal cases in humans infected with ... Hu Z, Ai H, Wang Z, Huang S, Sun H, Xuan X, Chen M. Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens. NPJ Vaccines. 2025 Apr 4;10(1):67. Abstract
submitted by kickingbird at Apr, 7, 2025 from NPJ Vaccines. 2025 Apr 4;10(1):67 (via https://www.nature.com/articles/s41541-025-01115-y)
H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We ... Chen PL, Richardson RA, Rovito S, Yang G, Writt HN. Live-attenuated pandemic H1N1 influenza vaccines expressing computationally optimized broadly reactive antigens (COBRAs) are immunogenic and protective in mice and ferrets. Vaccine. 2025 Apr 4;53:127090. Abstract
submitted by kickingbird at Apr, 7, 2025 from Vaccine. 2025 Apr 4;53:127090 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Computationally optimized broadly reactive antigens (COBRAs) induce broad and protective immune responses across multiple viral vaccine platforms. However, their suitability for incorporation into live ... Wagoner, Zachary W. et al.. Systems immunology analysis of human immune organoids identifies host-specific correlates of protection to different influenza vaccines. Cell Stem Cell, Volume 32, Issue 4, 529 - 546.e6. Abstract
submitted by kickingbird at Apr, 6, 2025 from Cell Stem Cell, Volume 32, Issue 4, 529 - 546.e6 (via https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)0)
Vaccines are an essential tool to significantly reduce pathogen-related morbidity and mortality. However, our ability to rationally design vaccines and identify correlates of protection remains limited. ... Xiao X, Wang X, Xu F, Liang Y, Luo Y, Li S, Zhou P. Synergistic effects of PA (S184N) and PB2 (E627K) mutations on the increased pathogenicity of H3N2 canine influenza virus infections in mice and dogs. J Virol. 2025 Apr 4:e0198424. Abstract
submitted by kickingbird at Apr, 5, 2025 from J Virol. 2025 Apr 4:e0198424 (via https://journals.asm.org/doi/10.1128/jvi.01984-24)
As companion animals, dogs are susceptible to various subtypes of influenza A virus (IAV), with the H3N2 and H3N8 subtypes of canine influenza virus (CIV) stably circulating among canines. Compared to ... Arbani O, Ducatez MF, Kadja-Wonou M, Salamat F, Ki. Development of an experimental model using cold stress to assess the pathogenicity of two Moroccan AI H9N2 isolates from 2016 and 2022 in commercial broiler chickens. PLoS One. 2025 Apr 4;20(4):e0320666. Abstract
submitted by kickingbird at Apr, 5, 2025 from PLoS One. 2025 Apr 4;20(4):e0320666 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since 2016, low pathogenic avian influenza virus (LPAIV) H9N2 became a major issue for poultry production in Morocco. Even though the agent was classified as low pathogenic, AI H9N2 cause significant economic ... Lindsey R Robinson-McCarthy, etc.,al. [preprint]Dairy cattle herds mount a characteristic antibody response to highly pathogenic H5N1 avian influenza viruses. https://doi.org/10.1101/2025.04.01.646587. Abstract
submitted by kickingbird at Apr, 2, 2025 from https://doi.org/10.1101/2025.04.01.646587 (via https://www.biorxiv.org/content/10.1101/2025.04.01.646587v1)
An unprecedented outbreak of a highly pathogenic avian influenza virus, H5 clade 2.3.4.4b, was reported in United States dairy cattle during the spring of 2024. It has now spread to hundreds of herds across ... Liu, Y., Deng, S., Ren, S. et al. Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models. Nat Commun 16, 3133 (2025). Abstract
submitted by kickingbird at Apr, 2, 2025 from Nat Commun 16, 3133 (2025) (via https://link.springer.com/article/10.1038/s41467-025-58504-z)
The highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in aquatic birds since 1997, causing outbreaks in domestic poultry and occasional human infections worldwide. Recently, the cross-species ... zhu-nan Li, etc.,al. [preprint]Population Immunity to Hemagglutinin Head, Stalk and Neuraminidase of Highly Pathogenic Avian Influenza 2.3.4.4b A(H5N1) viruses in the United States and the Impact of Seasonal Influenza on. https://doi.org/10.1101/2025.03.30.25323419. Abstract
submitted by kickingbird at Apr, 1, 2025 from https://doi.org/10.1101/2025.03.30.25323419 (via https://www.medrxiv.org/content/10.1101/2025.03.30.25323419v)
The unprecedented 2.3.4.4b A(H5N1) outbreak in dairy cattle, poultry, and spillover to humans in the United States (US) poses a major public health threat. Population immunity is a critical component of ... Ramya S Barre, etc.,al. [preprint]A Human H5N1 Influenza Virus Expressing Bioluminescence for Evaluating Viral Infection and Identifying Therapeutic Interventions. https://doi.org/10.1101/2025.03.28.646035. Abstract
submitted by kickingbird at Mar, 31, 2025 from https://doi.org/10.1101/2025.03.28.646035 (via https://www.biorxiv.org/content/10.1101/2025.03.28.646035v1)
A multistate outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in dairy cows was first reported on March 25, 2024, in the United States (US), marking the first discovery of HPAIV H5N1 in ... Ahmed Mostafa, etc.,al. [preprint]A Live Attenuated Vaccine Candidate against Emerging Highly Pathogenic Cattle-Origin 2.3.4.4b H5N1 Viruses. https://doi.org/10.1101/2025.03.28.646033. Abstract
submitted by kickingbird at Mar, 31, 2025 from https://doi.org/10.1101/2025.03.28.646033 (via https://www.biorxiv.org/content/10.1101/2025.03.28.646033v1)
Influenza viruses present a significant public health risk, causing substantial illness and death in humans each year. Seasonal flu vaccines must be updated regularly, and their effectiveness often decreases ... Jia Li, Tangqi Wang, Xiaojuan Guo, Yujie Jiang,etc. Broad Mucosal and Systemic Immunity in Mice Induced by Intranasal Booster With a Novel Recombinant Adenoviral Based Vaccine Protects Against Divergent Influenza A Virus. Journal of Medical Virology. Abstract
submitted by kickingbird at Mar, 31, 2025 from Journal of Medical Virology (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70326)
The development of broad-spectrum universal influenza vaccines and optimization of vaccination strategies to address the threats posed by pandemics and emerging influenza viruses are critical for public ... Phrutsamon Wongnak, etc.,al. [preprint]Characterising viral clearance kinetics in acute influenza. https://doi.org/10.1101/2025.03.07.25323547. Abstract
submitted by kickingbird at Mar, 31, 2025 from https://doi.org/10.1101/2025.03.07.25323547 (via https://www.medrxiv.org/content/10.1101/2025.03.07.25323547v)
Pharmacometric assessment of antiviral efficacy in acute influenza informs treatment decisions and pandemic preparedness. We assessed natural viral clearance in untreated acute influenza to guide clinical ... Poulami Basu Thakur, etc.,al. [preprint]Heterogeneity across mammalian- and avian-origin A(H1N1) influenza viruses influences viral infectivity following incubation with host bacteria from the human respiratory tract. https://doi.org/10.1101/2025.03.28.645935. Abstract
submitted by kickingbird at Mar, 31, 2025 from https://doi.org/10.1101/2025.03.28.645935 (via https://www.biorxiv.org/content/10.1101/2025.03.28.645935v1)
Influenza A viruses (IAV) are primarily transmitted between mammals by the respiratory route, and encounter bacteria in the respiratory tract before infecting susceptible epithelial cells. Previous studies ... Li L, Chen R, Yan Z, Cai Q, Guan Y, Zhu H. Experimental Infection of Rats with Influenza A Viruses: Implications for Murine Rodents in Influenza A Virus Ecology. Viruses. 2025; 17(4):495. Abstract
submitted by kickingbird at Mar, 31, 2025 from Viruses. 2025; 17(4):495 (via https://www.mdpi.com/1999-4915/17/4/495)
Rattus norvegicus (brown rat), a widely distributed rodent and common biomedical model, is a known reservoir for many zoonotic pathogens but has not been traditionally recognized as a host for influenza ... Guangxu Zhang, Yuren Shi, Haoyu Ge, Yuanzhou Wang,. Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies. Current Research in Microbial Sciences. Abstract
submitted by kickingbird at Mar, 31, 2025 from Current Research in Microbial Sciences (via https://www.sciencedirect.com/science/article/pii/S266651742)
The recent report of the first fatality associated with infection by influenza virus H5N1 clade 2.3.4.4b, identified as genotype D1.1, which is distinct from the B3.13 genotype, has sparked fears of a ... Frutos AM, Tenforde MW, Sundaresan D, Naleway AL,. Influenza-associated hospitalization rates by underlying conditions, 2016-17 to 2019-20: A retrospective cohort study. J Infect Dis. 2025 Mar 28:jiaf164. Abstract
submitted by kickingbird at Mar, 30, 2025 from J Infect Dis. 2025 Mar 28:jiaf164 (via https://pubmed.ncbi.nlm.nih.gov/40155312/)
Background: Various underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.Methods: Retrospective ... Ishiguro N, Morioka I, Nakano T, Manabe A, Kawaguc. Clinical and Virologic Outcomes of Baloxavir Compared with Oseltamivir in Pediatric Patients with Influenza in Japan. Infect Dis Ther. 2025 Mar 28. Abstract
submitted by kickingbird at Mar, 30, 2025 from Infect Dis Ther. 2025 Mar 28 (via https://pubmed.ncbi.nlm.nih.gov/40155497/)
Introduction: Baloxavir marboxil, a cap-dependent endonuclease inhibitor, has proven efficacy against influenza. There are limited comparative data between baloxavir and oseltamivir in Japanese pediatric ... Aaron M Frutos, Mark W Tenforde, Devi Sundaresan,. Influenza-associated hospitalization rates by underlying conditions, 2016~17 to 2019~20: A retrospective cohort study. The Journal of Infectious Diseases, 2025;, jiaf164. Abstract
submitted by kickingbird at Mar, 29, 2025 from The Journal of Infectious Diseases, 2025;, jiaf164 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
BackgroundVarious underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.MethodsRetrospective cohorts ... Yu L, Jiang Y, Rang H, Wang X, Cai Y, Yan H, Wu S,. Restriction of influenza A virus replication by host DCAF7-CRL4B axis. J Virol. 2025 Mar 27:e0013325. Abstract
submitted by kickingbird at Mar, 28, 2025 from J Virol. 2025 Mar 27:e0013325 (via https://journals.asm.org/doi/10.1128/jvi.00133-25)
The balance between cellular defense and viral escape determines the fate of influenza A virus (IAV) infection. Viral polymerase activity is critical for the replication and propagation of IAV. The antiviral ... 6604 items, 20/Page, Page[38/331][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
