Hugo Castelan-Sanchez, Art Poon. [preprint]Phylogenetic discordance cannot identify genomic reassortment events: a case study with the avian influenza virus H5Nx. https://doi.org/10.1101/2025.02.24.639875. Abstract
submitted by kickingbird at Mar, 2, 2025 from https://doi.org/10.1101/2025.02.24.639875 (via https://www.biorxiv.org/content/10.1101/2025.02.24.639875v1)
Recombination plays a central role in the evolution of the RNA virus genome, as it allows the exchange of genetic material between different viral lineages. Reassortment is a form of recombination specific ... Murray J, Nogales A, Martinez-Sobrido L, Martin DE. Evaluating Probenecid or Oseltamivir Inhibition of Influenza A Virus Replication Through Plaque Assay or Fluorescent Focus Assay Using Non-Structural Protein 1–H1N1 Venus Reporter Virus. Viruses. 2025; 17(3):335. Abstract
submitted by kickingbird at Mar, 2, 2025 from Viruses. 2025; 17(3):335 (via https://www.mdpi.com/1999-4915/17/3/335)
It is essential to understand the molecular mechanisms of influenza antiviral therapeutics to evaluate their efficacy. Virus plaque assays are commonly used to assess the antiviral effects of drugs on ... Yu X, Su N, Luo J, Zhang D, Zhang H, Duan M, Shi N. Long noncoding RNA USP30-AS1 promotes influenza A virus replication by enhancing PHB1 function. Vet Microbiol. 2025 Feb 26;303:110444. Abstract
submitted by kickingbird at Mar, 2, 2025 from Vet Microbiol. 2025 Feb 26;303:110444 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Long noncoding RNAs (lncRNAs) are important regulators of gene expression. Although evidence accumulated over the past decade shows that lncRNAs have key roles in the interaction between viruses and hosts, ... Zhu Y, Cong Y, Sun Y, Sheng S, Liu C, Jiang J, Li. Molecular patterns of matrix protein 1 (M1): A strong predictor of adaptive evolution in H9N2 avian influenza viruses. Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e24239. Abstract
submitted by kickingbird at Mar, 1, 2025 from Proc Natl Acad Sci U S A. 2025 Mar 4;122(9):e24239 (via https://www.pnas.org/doi/10.1073/pnas.2423983122)
The H9N2 subtype of avian influenza virus (AIV) emerges as a significant member of the influenza A virus family. However, the varying degrees of epidemiological dominance among different lineages or clades ... Kirill Vasilev, etc.,al. [preprint]Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza virus vaccine adjuvanted with bacterial cell membrane-derived adjuvants. https://doi.org/10.1101/2025.02.26.640278. Abstract
submitted by kickingbird at Feb, 27, 2025 from https://doi.org/10.1101/2025.02.26.640278 (via https://www.biorxiv.org/content/10.1101/2025.02.26.640278v1)
Influenza virus neuraminidase (NA) has emerged as a promising vaccine candidate due to its relatively stable antigenic structure and the ability of NA-specific antibodies to provide cross-protection within ... Augustin Clessin, etc.,al. [preprint]Mass mortality events in the sub-Antarctic Indian Ocean caused by long-distance circumpolar spread of highly pathogenic avian influenza H5N1 clade 2.3.4.4b. https://doi.org/10.1101/2025.02.25.640068. Abstract
submitted by kickingbird at Feb, 27, 2025 from https://doi.org/10.1101/2025.02.25.640068 (via https://www.biorxiv.org/content/10.1101/2025.02.25.640068v1)
Since 2020, the outbreak of highly pathogenic avian influenza (HPAI) virus clade 2.3.4.4b has turned into the largest documented panzootic to date, reaching the sub-Antarctic region and Antarctica via ... Hermann E, Krammer F. Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020. mBio. 2025 Feb 26:e0398924. Abstract
submitted by kickingbird at Feb, 27, 2025 from mBio. 2025 Feb 26:e0398924 (via https://journals.asm.org/doi/10.1128/mbio.03989-24)
Since 2020, H5N1 highly pathogenic avian influenza (HPAI) viruses of clade 2.3.4.4b have been rapidly spreading in wild birds but have also caused a large number of mammalian infections and more than 70 ... Korsun N, Trifonova I, Pavlova D, Uzunova Y, Ivano. Etiological Spectrum of Acute Respiratory Infections in Bulgaria During the 2023-2024 Season and Genetic Diversity of Circulating Influenza Viruses. Viruses. 2025 Feb 16;17(2):270. Abstract
submitted by kickingbird at Feb, 27, 2025 from Viruses. 2025 Feb 16;17(2):270 (via https://www.mdpi.com/1999-4915/17/2/270)
Influenza poses a serious threat to both individual and public health. This study aimed to investigate the virological and epidemiological characteristics of influenza infections and to explore the genetic ... Chen M, Hu J, Zhou X, Gao M, Li N, Yang G, Chi X,. Long Non-Coding RNA THRIL Promotes Influenza Virus Replication by Inhibiting the Antiviral Innate Immune Response. Viruses. 2025 Jan 23;17(2):153. Abstract
submitted by kickingbird at Feb, 27, 2025 from Viruses. 2025 Jan 23;17(2):153 (via https://www.mdpi.com/1999-4915/17/2/153)
Long non-coding RNAs (lncRNAs) have been recognized for their crucial roles in the replication processes of various viruses. However, the specific functions and regulatory mechanisms of many lncRNAs in ... Hao T, Xie Y, Chai Y, Zhang W, Zhang D, Qi J, Shi. Structural basis of receptor-binding adaptation of human-infecting H3N8 influenza A virus. J Virol. 2025 Feb 24:e0106524. Abstract
submitted by kickingbird at Feb, 25, 2025 from J Virol. 2025 Feb 24:e0106524 (via https://journals.asm.org/doi/10.1128/jvi.01065-24)
Recent avian-origin H3N8 influenza A virus (IAV) that have infected humans pose a potential public health concern. Alterations in the viral surface glycoprotein, hemagglutinin (HA), are typically required ... Hayate Nishiura, etc.,al. Pathogenic and Antigenic Analyses of H5N1 High Pathogenicity Avian Influenza Virus Isolated in the 2022/2023 Season From Poultry Farms in Izumi City, Japan. Transboundary and Emerging Diseases, 23 Feb 2025. Abstract
submitted by kickingbird at Feb, 24, 2025 from Transboundary and Emerging Diseases, 23 Feb 2025 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1535116)
During the winter of 2022/2023, Japan experienced its largest outbreak of high pathogenicity avian influenza (HPAI), affecting 84 poultry premises. In this study, we investigated the pathogenicity and ... Guangwen Wang, etc.,al. Genome-wide siRNA library screening identifies human host factors that influence the replication of the highly pathogenic H5N1 influenza virus. mLife, 24 February 2025. Abstract
submitted by kickingbird at Feb, 24, 2025 from mLife, 24 February 2025 (via https://onlinelibrary.wiley.com/doi/10.1002/mlf2.12168)
The global dissemination of H5 avian influenza viruses represents a significant threat to both human and animal health. In this study, we conducted a genome-wide siRNA library screening against the highly ... Rio Harada, etc.,al. Altered receptor-binding specificity of gull-adapted H13 avian influenza viruses corresponds to their unique host preferences. Virology April 2025. Abstract
submitted by kickingbird at Feb, 24, 2025 from Virology April 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Avian influenza viruses (AIVs) recognize α2-3 sialosides as receptors. Previous studies showed that the structural diversity within α2-3 sialosides is related to the host specificity of AIVs. H13 AIVs ... Sun X, Belser JA, Li Z-N, Brock N, Pulit-Penaloza. Effect of Prior Influenza A(H1N1)pdm09 Virus Infection on Pathogenesis and Transmission of Human Influenza A(H5N1) Clade 2.3.4.4b Virus in Ferret Model. Emerg Infect Dis. 2025 Mar. Abstract
submitted by kickingbird at Feb, 24, 2025 from Emerg Infect Dis. 2025 Mar (via https://wwwnc.cdc.gov/eid/article/31/3/24-1489_article)
Reports of human infections with an influenza A(H5N1) clade 2.3.4.4b virus associated with outbreaks in dairy cows in the United States underscore the need to assess the potential cross-protection conferred ... Le Sage V, Werner BD, Merrbach GA, Petnuch SE, O’C. Influenza A(H5N1) Immune Response among Ferrets with Influenza A(H1N1)pdm09 Immunity. Emerg Infect Dis. 2025 Mar. Abstract
submitted by kickingbird at Feb, 24, 2025 from Emerg Infect Dis. 2025 Mar (via https://wwwnc.cdc.gov/eid/article/31/3/24-1485_article)
The emergence of highly pathogenic avian influenza A(H5N1) virus in dairy cattle herds across the United States in 2024 caused several human infections. Understanding the risk for spillover infections ... Yu X, Ni Z, Wang Y, Wang J, Deng G, Shi J, Kong H,. Claudin-11 plays a pivotal role in the clathrin-mediated endocytosis of influenza A virus. Sci China Life Sci. 2025 Feb 20. Abstract
submitted by kickingbird at Feb, 24, 2025 from Sci China Life Sci. 2025 Feb 20 (via https://link.springer.com/article/10.1007/s11427-024-2856-y)
Identification of host factors that play a key role in viral replication is of great importance for antiviral development. Metabotropic glutamate receptor subtype 2 (mGluR2) is the receptor to trigger ... Echeverri-De la Hoz D, Martínez-Bravo C, Gastelbon. Genomics of novel influenza A virus (H18N12) in bats, Caribe Colombia. Sci Rep. 2025 Feb 22;15(1):6507. Abstract
submitted by kickingbird at Feb, 24, 2025 from Sci Rep. 2025 Feb 22;15(1):6507 (via https://www.nature.com/articles/s41598-025-91026-8)
Influenza viruses are highly capable of mutating and adapting in mammalian hosts. While these viruses have been extensively studied in birds, research on their presence in bats has been limited. However, ... Karla M Castro, etc.,al. [preprint]Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity. https://doi.org/10.1101/2024.12.17.628867. Abstract
submitted by kickingbird at Feb, 24, 2025 from https://doi.org/10.1101/2024.12.17.628867 (via https://www.biorxiv.org/content/10.1101/2024.12.17.628867v2)
Antigenic variability among influenza virus strains poses a significant challenge to developing broadly protective, long-lasting vaccines. Current annual vaccines target specific strains, requiring accurate ... Garazi Pena Alzua, etc.,al. [preprint]Human monoclonal antibodies that target clade 2.3.4.4b H5N1 hemagglutinin. https://doi.org/10.1101/2025.02.21.639446. Abstract
submitted by kickingbird at Feb, 24, 2025 from https://doi.org/10.1101/2025.02.21.639446 (via https://www.biorxiv.org/content/10.1101/2025.02.21.639446v1)
The highly pathogenic avian influenza H5N1 virus clade 2.3.4.4b has been spreading globally since 2022, causing mortality and morbidity in domestic and wild birds and mammals, including infection in humans, ... Oona Liedes, etc.,al. [preprint]Inactivated Zoonotic Influenza A(H5N8) Vaccine Induces Robust Antibody Responses Against Recent Highly Pathogenic Avian Influenza Clade 2.3.4.4b A(H5N1) Viruses. https://doi.org/10.1101/2025.02.12.25322044. Abstract
submitted by kickingbird at Feb, 22, 2025 from https://doi.org/10.1101/2025.02.12.25322044 (via https://www.medrxiv.org/content/10.1101/2025.02.12.25322044v)
In 2023, Finland faced an outbreak of highly pathogenic avian influenza caused by clade 2.3.4.4b A(H5N1) viruses, which spread from wild birds to fur farms. Vaccinations of individuals at-risk, such as ... 6469 items, 20/Page, Page[35/324][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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