Robert G. Webster and Elena A. Govorkova. H5N1 Influenza - Continuing Evolution and Spread. NEJM, 2006, 355(21):2174-7. Full Text
submitted by kickingbird at Dec, 21, 2006 from NEJM, 2006, 355(21):2174-7 (via http://content.nejm.org/cgi/content/full/355/21/2174)
There is no question that there will be another influenza pandemic someday. We simply don't know when it will occur or whether it will be caused by the H5N1 avian influenza virus. But given the number ... Shin YK, Liu Q, Tikoo SK, Babiuk LA, Zhou Y. Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K. J Gen Virol. 2007 Jan;88(Pt 1):13-8.. Abstract
submitted by kickingbird at Dec, 20, 2006 from J Gen Virol. 2007 Jan;88(Pt 1):13-8. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza A virus infection activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, but the mechanism is not clear. Here, it is reported that influenza A virus NS1 protein is responsible for PI3K/Akt ... Feng J, Zhang M, Mozdzanowska K, Zharikova D, Hoff. Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virol J. 2006 Dec 6;3(1):102. Abstract
submitted by kickingbird at Dec, 14, 2006 from Virol J. 2006 Dec 6;3(1):102 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
ABSTRACT: BACKGROUND: Matrix protein 2 (M2) is an integral tetrameric membrane protein of influenza A virus (IAV). Its ectodomain (M2e) shows remarkably little diversity amongst human IAV strains. As M2e-specific ... Burleson GR, Burleson FG. fluenza virus host resistance model. Methods. 2007 Jan;41(1):31-7. Abstract
submitted by kickingbird at Dec, 14, 2006 from Methods. 2007 Jan;41(1):31-7 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Host resistance (HR) models are used to evaluate the effect of a test article on clearance of an infectious microorganism in order to assess total immunocompetence. HR models serve as biomarkers of net ... Gabriel Sertsou, etc.,al. Key transmission parameters of an institutional outbreak during the 1918 influenza pandemic estimated by mathematical modelling. Theoretical Biology and Medical Modelling 2006, 3:. Full Text
submitted by kickingbird at Dec, 7, 2006 from Theoretical Biology and Medical Modelling 2006, 3: (via http://www.tbiomed.com/content/3/1/38)
Aim: To estimate the key transmission parameters associated with an outbreak of pandemic influenza in an institutional setting (New Zealand 1918).
Methods
Historical morbidity and mortality data were ... Baz M, Abed Y, Boivin G. Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir. Antiviral Res. 2006 Nov 20. Abstract
submitted by kickingbird at Dec, 7, 2006 from Antiviral Res. 2006 Nov 20 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
There is a limited information with regard to the neuraminidase (NA) mutations conferring resistance to peramivir and zanamivir in the influenza N1 background. In this study, an influenza A/WSN/33 (H1N1) ... Harris A, Cardone G, Winkler DC, Heymann JB, Brech. Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci U S A. 2006 Dec 4. Abstract
submitted by kickingbird at Dec, 7, 2006 from Proc Natl Acad Sci U S A. 2006 Dec 4 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Influenza virus remains a global health threat, with millions of infections annually and the impending threat that a strain of avian influenza may develop into a human pandemic. Despite its importance ... Uchide N, Ohyama K, Bessho T, Toyoda H. Effects of Mitogen-Activated Protein Kinase Inhibitors on Tumor Necrosis Factor-alpha Gene Expression and Apoptosis Induction in Cultured Human Fetal Membrane Chorion Cells Infected with Influenza Vir. Intervirology. 2006 Nov 30;50(2):99-107. Abstract
submitted by kickingbird at Dec, 4, 2006 from Intervirology. 2006 Nov 30;50(2):99-107 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
We investigated the involvement of p38 mitogen-activated protein (MAP) kinase in tumor necrosis factor (TNF)-alpha gene expression, apoptosis induction and virus replication in cultured human fetal membrane ... Shiratsuchi A, Nakanishi Y. Elimination of Influenza Virus-infected Cells by Phagocytosis. Yakugaku Zasshi. 2006 Dec;126(12):1245-51. Abstract
submitted by kickingbird at Dec, 4, 2006 from Yakugaku Zasshi. 2006 Dec;126(12):1245-51 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Infection with a variety of viruses induces apoptosis in host cells. This phenomenon may be considered to be a self-defense mechanism to avoid viral propagation. However, the growth of influenza virus ... Wu G, Yan S. Fate of 130 hemagglutinins from different influenza A viruses. Biochem Biophys Res Commun. 2004 May 7;317(3):917-24. Abstract
submitted by DreamSciTech at Nov, 29, 2006 from Biochem Biophys Res Commun. 2004 May 7;317(3):917-24 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
In this study, we use our probabilistic models to analyze 130 hemagglutinins from different influenza A virus in order to gain the insight into their fate. The results provide three lines of evidence regarding ... Zheng M, Yu K, Liu H, Luo X, Chen K, Zhu W, Jiang. QSAR analyses on avian influenza virus neuraminidase inhibitors using CoMFA, CoMSIA, and HQSAR. J Comput Aided Mol Des. 2006 Sep;20(9):549-66.. Abstract
submitted by kickingbird at Nov, 28, 2006 from J Comput Aided Mol Des. 2006 Sep;20(9):549-66. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
The recent wide spreading of the H5N1 avian influenza virus (AIV) in Asia, Europe and Africa and its ability to cause fatal infections in human has raised serious concerns about a pending global flu pandemic. ... Naito T, Momose F, Kawaguchi A, Nagata K. Involvement of Hsp90 in assembly and nuclear import of the influenza virus RNA polymerase subunits. J Virol. 2006 Nov 22; [Epub ahead of print]. Abstract
submitted by kickingbird at Nov, 28, 2006 from J Virol. 2006 Nov 22; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Transcription and replication of the influenza virus RNA genome occur in the nuclei of infected cells through the viral RNA-dependent RNA polymerase consisting of PB1, PB2, and PA. We previously identified ... S.O. Rogers, etc.,al. Evidence of Influenza A Virus RNA in Siberian Lake Ice. Journal of Virology, Vol. 80, No.24, p.12229-12235. Abstract
submitted by kickingbird at Nov, 28, 2006 from Journal of Virology, Vol. 80, No.24, p.12229-12235 (via http://jvi.asm.org/cgi/content/abstract/80/24/12229?etoc)
Influenza A virus infects a large proportion of the human population annually, sometimes leading to the deaths of millions. The biotic cycles of infection are well characterized in the literature, including ... Gao YW. Evolution of H5N1 Influenza Virus from Tigers and Lions and Construction of Recombinant Canine Adenovirus Type2 Expressing Hemagglutinin Gene. Ph.D Thesis, Jilin University. Abstract
submitted by kickingbird at Nov, 26, 2006 from Ph.D Thesis, Jilin University (via http://www.cnki.net)
Evolution of H5N1 Influenza Virus from Tigers and Lionsand Construction of Recombinant Canine Adenovirus Type2 Expressing Hemagglutinin GenePh. D. Candidate: Gao Yu-weiAdvisor：Xia Xian-zhu，Membership of ... Bright RA, Shay DK, Shu B, Cox NJ, Klimov AI. Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA. 2006 Feb 22;295(8):891-4. Epub 2006 Feb 2. Abstract
submitted by kickingbird at Nov, 26, 2006 from JAMA. 2006 Feb 22;295(8):891-4. Epub 2006 Feb 2 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The adamantanes, amantadine and rimantadine, have been used as first-choice antiviral drugs against community outbreaks of influenza A viruses for many years. Rates of viruses resistant to these drugs ... Payungporn S, Chutinimitkul S, Chaisingh A, Damron. Single step multiplex real-time RT-PCR for H5N1 influenza A virus detection. J Virol Methods. 2006 Feb;131(2):143-7. Epub 2005. Abstract
submitted by kickingbird at Nov, 26, 2006 from J Virol Methods. 2006 Feb;131(2):143-7. Epub 2005 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
H5N1 influenza A virus causes a rapidly fatal systemic disease in domestic poultry and spreads directly from poultry to mammalian species such as leopards, tigers and humans. The aim of this study was ... Suwannakarn K, Chutinimitkul S, Payungporn S, Chie. Assay to Detect H5N1 Oseltamivir Resistance. Emerg Infect Dis. 2006 Dec. Full Text
submitted by kickingbird at Nov, 26, 2006 from Emerg Infect Dis. 2006 Dec (via http://www.cdc.gov/ncidod/EID/vol12no12/06-0673.htm)
Oseltamivir is a neuraminidase inhibitor approved for treatment and prevention of influenza virus infection. Oseltamivir resistance caused by a single amino acid substitution from histidine (H) to tyrosine ... Dinh PN, Long HT, Tien NTK, Hien NT, Mai LTQ, Phon. Risk Factors for Human Infection with Avian Influenza A H5N1, Vietnam, 2004. Emerg Infect Dis. 2006 Dec. Full Text
submitted by kickingbird at Nov, 26, 2006 from Emerg Infect Dis. 2006 Dec (via http://www.cdc.gov/ncidod/EID/vol12no12/06-0829.htm)
To evaluate risk factors for human infection with influenza A subtype H5N1, we performed a matched case-control study in Vietnam. We enrolled 28 case-patients who had laboratory-confirmed H5N1 infection ... Weltman JK, Skowron G, Loriot GB. Influenza A H5N1 hemagglutinin cleavable signal sequence substitutions. Biochem Biophys Res Commun. 2006 Nov 10. Abstract
submitted by kickingbird at Nov, 23, 2006 from Biochem Biophys Res Commun. 2006 Nov 10 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Eleven influenza A H5N1 hemagglutinin N-terminal cleavable signal sequences, coded by single nucleotide substitutions relative to reference A/Viet Nam/1203/2004, were identified by BLASTN search of GenBank ... Mase M, Tanimura N, Imada T, Okamatsu M, Tsukamoto. Recent H5N1 avian Influenza A virus increases rapidly in virulence to mice after a single passage in mice. J Gen Virol. 2006 Dec;87(Pt 12):3655-9.. Abstract
submitted by kickingbird at Nov, 23, 2006 from J Gen Virol. 2006 Dec;87(Pt 12):3655-9. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
To evaluate the potential pathogenicity to mammals of the recent H5N1 avian Influenza A virus, viruses recovered from dead mice infected with A/chicken/Yamaguchi/7/2004 isolated in Japan were examined. ... 7184 items, 20/Page, Page[338/360][|<<] [|<] [331] [332] [333] [334] [335] [336] [337] [338] [339] [340] [>|] [>>|] |
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