Rebecca Daines, Jean-Remy Sadeyen, etc.,al. [preprint]Mapping Haemagglutinin Residues Driving Antigenic Diversity in H5Nx Avian Influenza Viruses. https://doi.org/10.1101/2025.06.18.660338. Abstract
submitted by kickingbird at Jun, 20, 2025 from https://doi.org/10.1101/2025.06.18.660338 (via https://www.biorxiv.org/content/10.1101/2025.06.18.660338v1)
Since its emergence in 1996, the H5 avian influenza virus (AIV) A/Goose/Guangdong/1/1996 (Gs/GD) haemagglutinin (HA) has evolved into over 30 genetically and antigenically distinct clades, including the ... Ana Moreno, etc.,al. [preprint]nactivation of Influenza A Viruses (H1N1, H5N1) During Grana-Type Raw Milk Cheesemaking: Implications for Foodborne Transmission Risk. https://doi.org/10.1101/2025.06.18.660327. Abstract
submitted by kickingbird at Jun, 20, 2025 from https://doi.org/10.1101/2025.06.18.660327 (via https://www.biorxiv.org/content/10.1101/2025.06.18.660327v1)
Background: The detection of H5N1 highly pathogenic avian influenza virus (HPAIV) in lactating dairy cattle in the United States, with high viral titers in raw milk, has raised concerns about potential ... Matthew Scotch, etc.,al. [preprint]Campus-based genomic surveillance uncovers early emergence of a future dominant A(H3N2) influenza clade. https://doi.org/10.1101/2025.06.13.25329559. Abstract
submitted by kickingbird at Jun, 19, 2025 from https://doi.org/10.1101/2025.06.13.25329559 (via https://www.medrxiv.org/content/10.1101/2025.06.13.25329559v)
We conducted genomic surveillance of seasonal influenza during the 2022-2023 northern hemisphere flu season on a large university setting in Southwest Arizona USA to understand the diversity, evolution, ... Lan J, Liu L, Li X, Ding R, Zhu J, Qu F, Zhai B, W. H13N8 and H16N3 AIV Isolated From Shorebirds Can Replicate in the Rectum of Mice. J Med Virol. 2025 Jun;97(6):e70455. Abstract
submitted by kickingbird at Jun, 18, 2025 from J Med Virol. 2025 Jun;97(6):e70455 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70455)
To investigate the pathogenicity and cross-species transmission potential of H13 and H16-subtype of low pathogenic avian influenza viruses (LPAIVs), two strains of H13N8 and H16N3 isolated from shorebirds ... Yue, Y., Li, Q., Chen, C. et al. Purine nucleoside phosphorylase dominates Influenza A virus replication and host hyperinflammation through purine salvage. Sig Transduct Target Ther 10, 191 (2025). Abstract
submitted by kickingbird at Jun, 17, 2025 from Sig Transduct Target Ther 10, 191 (2025) (via https://link.springer.com/article/10.1038/s41392-025-02272-1)
Influenza A virus (IAV) poses a significant threat to human health. The outcome of IAV results from the viral-host interaction, with the underlying molecular mechanisms largely unknown. By integrating ... Kwon, T., Trujillo, J. D., Carossino, M., Machkove. Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. Emerging Microbes Infections, 14(1). Abstract
submitted by kickingbird at Jun, 17, 2025 from Emerging Microbes Infections, 14(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching 17 states and at least 1000 dairy herds in the United States. ... Bian J, Fung J, Lee LK, Tam WY, Wong LC, Wong CK,. Genetic Characterization of Influenza A Viruses Circulating in Hong Kong, China, 2023: The first influenza epidemic after the lifting of 2.5 years of COVID-19 non-pharmaceutical interventions. Emerg Microbes Infect. 2025 Jun 16:2521850. Abstract
submitted by kickingbird at Jun, 17, 2025 from Emerg Microbes Infect. 2025 Jun 16:2521850 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
During the COVID-19 pandemic, stringent public health measures led to historically low influenza activity in Hong Kong. However, after these interventions were relaxed in 2023, Influenza A viruses (IAV), ... Jones JE, Lakdawala SS. Host origin is a determinant of coevolution between gene segments of avian H9 influenza viruses. J Virol. 2025 Jun 13:e0151824. Abstract
submitted by kickingbird at Jun, 15, 2025 from J Virol. 2025 Jun 13:e0151824 (via https://journals.asm.org/doi/10.1128/jvi.01518-24)
Several emerging influenza viruses, including H7N9 and H5N6 viruses, trace their origins to reassortment with H9N2 viruses that contributed internal gene segments. However, the evolutionary constraints ... hi L, Lang Y, Roy S, Shen Z, Gupta D, Dai C, Khali. Outcomes of experimental infection of calves with swine influenza H3N2 virus. mBio 0:e03957-24. Abstract
submitted by kickingbird at Jun, 13, 2025 from mBio 0:e03957-24 (via https://journals.asm.org/doi/10.1128/mbio.03957-24)
Unprecedented outbreaks caused by the H5N1 highly pathogenic avian influenza virus (HPAIV) among dairy cows in the United States have raised significant concerns. Whether other subtypes of influenza A ... Maria Ogrzewalska, etc.,al. [preprint]Genomic analysis of high pathogenicity avian influenza viruses from Antarctica reveals multiple introductions from South America. https://doi.org/10.21203/rs.3.rs-6727501/v1. Abstract
submitted by kickingbird at Jun, 13, 2025 from https://doi.org/10.21203/rs.3.rs-6727501/v1 (via https://www.researchsquare.com/article/rs-6727501/v1)
The spread of high pathogenicity avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b into Antarctica represents a major threat to polar wildlife. Here we report on the detection and genomic analysis of HPAIV ... Jiang M, Zou J, Jin Y, Jiang C, Tu S, Chen T, Guo. Adducin-1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity. Adv Sci (Weinh). 2025 Jun 5:e2417318. Abstract
submitted by kickingbird at Jun, 12, 2025 from Adv Sci (Weinh). 2025 Jun 5:e2417318 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
Actin- and microtubule-based transport systems are essential for the trafficking of endocytic viruses and cargoes. Microtubules facilitate long-distance transport; however, the precise role of actin dynamics ... Sullivan OM, Nesbitt DJ, Schaack GA, Feltman EM, N. IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency. J Virol. 2025 Jun 11:e0028625. Abstract
submitted by kickingbird at Jun, 12, 2025 from J Virol. 2025 Jun 11:e0028625 (via https://journals.asm.org/doi/10.1128/jvi.00286-25)
Host cells produce a vast network of antiviral factors in response to viral infection. The interferon-induced proteins with tetratricopeptide repeats (IFITs) are important effectors of a broad-spectrum ... Yang, B., Gostic, K.M., Adam, D.C. et al. Breadth of influenza A antibody cross-reactivity varies by virus isolation interval and subtype. Nat Microbiol (2025). Abstract
submitted by kickingbird at Jun, 11, 2025 from Nat Microbiol (2025) (via https://link.springer.com/article/10.1038/s41564-025-02033-4)
Influenza virus infections generate antibodies that cross-react with antigenically similar viruses. However, the breadth of cross-reactivity is unclear. Here we analysed 200,000 haemagglutination inhibition ... Mojsiejczuk L, Whitlock F, Chen H, Magill C, Arand. Multiple introductions of equine influenza virus into the United Kingdom resulted in widespread outbreaks and lineage replacement. PLoS Pathog. 2025 Jun 9;21(6):e1013227. Abstract
submitted by kickingbird at Jun, 10, 2025 from PLoS Pathog. 2025 Jun 9;21(6):e1013227 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses (IAVs) are prime examples of emerging viruses in humans and animals. IAV circulation in domestic animals poses a pandemic risk as it provides new opportunities for zoonotic infections. ... Oade MS, Te Velthuis AJW. Molecular Insights into Noncanonical Influenza Virus Replication and Transcription. Annu Rev Virol. 2025 Jun 9. Abstract
submitted by kickingbird at Jun, 10, 2025 from Annu Rev Virol. 2025 Jun 9 (via https://www.annualreviews.org/content/journals/10.1146/annur)
Influenza A viruses (IAVs) typically cause a mild to moderate respiratory disease, whereas infections with pandemic and highly pathogenic avian IAV strains are frequently associated with high morbidity ... Martinez-Gzegozewska Y, Rasmussen L, Nebane NM, Mc. High-throughput screening for identification of Influenza A inhibitors using a cell-based immunofluorescence assay. Antiviral Res. 2025 Jun 6:106209. Abstract
submitted by kickingbird at Jun, 9, 2025 from Antiviral Res. 2025 Jun 6:106209 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
A highly sensitive cell-based imaging assay has been used to screen a 200,000 compounds library for potential influenza antivirals. Compounds were screened at a concentration of 10 μM against the influenza ... Song M, Liang J, Wang S, Gao R, Lu X, Yang W, Chen. E627V mutation in PB2 protein promotes the mammalian adaptation of novel H10N3 avian influenza virus. Vet Res. 2025 Jun 8;56(1):111. Abstract
submitted by kickingbird at Jun, 9, 2025 from Vet Res. 2025 Jun 8;56(1):111 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Since 2021, the novel H10N3 has caused four cases of human infection in China, the most recent of which occurred in December 2024, posing a potential threat to public health. Our previous studies indicated ... Gao, J., Landgraf, G., Yuan, Y. et al. Influenza neuraminidase active site proximity assay for rapid profiling of inhibitory antibodies and antigenic drift. npj Vaccines 10, 118 (2025). Abstract
submitted by kickingbird at Jun, 8, 2025 from npj Vaccines 10, 118 (2025) (via https://www.nature.com/articles/s41541-025-01173-2)
Efficient approaches that can help to select vaccine strains for the influenza virus neuraminidase (NA) antigen are currently needed to advance the development of vaccines containing NA. Here, we present ... Amalie B. Rasmussen, etc.,al. [preprint]Influenza A virus polymerase co-opts distinct sets of host proteins for RNA transcription or replication. https://doi.org/10.1101/2025.06.06.658254. Abstract
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.06.658254 (via https://www.biorxiv.org/content/10.1101/2025.06.06.658254v1)
The influenza A virus polymerase, consisting of a heterotrimer of three viral proteins, carries out both transcription and replication of the viral RNA genome. These distinct activities are regulated by ... Sayan Das, etc.,al. [preprint]Enhancing protective efficacy and immunogenicity of hemagglutinin-based influenza vaccine utilizing adjuvants developed by BECC. https://doi.org/10.1101/2025.06.03.657703. Abstract
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.03.657703 (via https://www.biorxiv.org/content/10.1101/2025.06.03.657703v1)
Seasonal influenza viruses continue to pose a significant threat, causing substantial morbidity and mortality in the US and worldwide despite the availability of vaccines and antivirals. These challenges ... 6604 items, 20/Page, Page[29/331][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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