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2024-5-10 23:42:18
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Zhang C, Cui H, Chen L, Yuan W, Dong S, Kong Y, Gu. Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Virus Clade 2.3.4.4h in Mammals. Viruses. 2022 Nov 5;14(11):2454.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Nov 5;14(11):2454 (via https://www.mdpi.com/1999-4915/14/11/2454)
Throughout the last decade, H5N6 avian influenza viruses (AIVs) circulating in poultry and infecting humans have caused increasing global concerns that they might become a pandemic threat to global health. ...

Phyu WW, Saito R, Kyaw Y, Lin N, Win SMK, Win NC,. Evolutionary Dynamics of Whole-Genome Influenza A/H3N2 Viruses Isolated in Myanmar from 2015 to 2019. Viruses. 2022 Oct 31;14(11):2414.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Oct 31;14(11):2414 (via https://www.mdpi.com/1999-4915/14/11/2414)
This study aimed to analyze the genetic and evolutionary characteristics of the influenza A/H3N2 viruses circulating in Myanmar from 2015 to 2019. Whole genomes from 79 virus isolates were amplified using ...

Petric PP, King J, Graf L, Pohlmann A, Beer M, Sch. Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA. Viruses. 2022 Oct 24;14(11):2331.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Oct 24;14(11):2331 (via https://www.mdpi.com/1999-4915/14/11/2331)
The interferon-induced myxovirus resistance protein A (MxA) is a potent restriction factor that prevents zoonotic infection from influenza A virus (IAV) subtype H7N9. Individuals expressing antivirally ...

Hu TY, Lian YB, Qian JH, Yang YL, Ata EB, Zhang RR. Immunogenicity of engineered probiotics expressing conserved antigens of influenza virus and FLIC flagellin against H9N2 AIVinfection in mice. Res Vet Sci. 2022 Oct 30;153:115-126.  Abstract  
submitted by kickingbird at Nov, 10, 2022 from Res Vet Sci. 2022 Oct 30;153:115-126 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
Avian influenza virus (AIV)is easy to cause diseases in birds and humans.It causes great economic losses to the poultry farms and leads to public health problems. Using vaccines is the main approach to ...

Jiang L, Li J, Cui H, Zhang C, Jin Y, Fu Y, Ma N,. Etiologic characteristics of avian influenza H11 viruses isolated from the live poultry market in southeast coastal region in China. Front Microbiol. 2022 Oct 21;13:1002670.  Abstract  
submitted by kickingbird at Nov, 9, 2022 from Front Microbiol. 2022 Oct 21;13:1002670 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.1002)
Since it was first identified in 1956, the H11 subvariant influenza virus has been reported worldwide. However, due to the low pathogenicity of the H11 subvariant and the absence of its widespread transmission ...

James J, Bhat S, Walsh SK, Karunarathna TK, Sadeye. The Origin of Internal Genes Contributes to the Replication and Transmission Fitness of H7N9 Avian Influenza Virus. J Virol. 2022 Nov 7:e0129022.  Abstract  
submitted by kickingbird at Nov, 9, 2022 from J Virol. 2022 Nov 7:e0129022 (via https://journals.asm.org/doi/10.1128/jvi.01290-22)
H9N2 avian influenza viruses (AIVs) have donated internal gene segments during the emergence of zoonotic AIVs, including H7N9. We used reverse genetics to generate A/Anhui/1/13 (H7N9) and three reassortant ...

Higazy D, Lin X, Xie T, Wang K, Gao X, Cui M. Altered gene expression in human brain microvascular endothelial cells in response to the infection of influenza H1N1 virus. Anim Dis. 2022;2(1):25.  Abstract  
submitted by kickingbird at Nov, 9, 2022 from Anim Dis. 2022;2(1):25 (via https://animaldiseases.biomedcentral.com/articles/10.1186/s4)
Influenza viruses not only cause respiratory illness, but also have been reported to elicit neurological manifestations following acute viral infection. The central nervous system (CNS) has a specific ...

Yang J, Yan J, Zhang C, Li S, Yuan M, Zhang C, She. Genetic, biological and epidemiological study on a cluster of H9N2 avian influenza virus infections among chickens, a pet cat, and humans at a backyard farm in Guangxi, China. Emerg Microbes Infect. 2022 Nov 3:1-42.  Abstract  
submitted by kickingbird at Nov, 4, 2022 from Emerg Microbes Infect. 2022 Nov 3:1-42 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
During an investigation in October 2018, two people with diarrhoea, mild abdominal pain, and mild arthralgia symptoms in Guangxi, China, were identified as infected by H9N2 avian influenza virus (AIV). ...

Mo JS, Abente EJ, Cardenas Perez M, Sutton TC, Cow. Transmission of Human Influenza A Virus in Pigs Selects for Adaptive Mutations on the HA Gene. J Virol. 2022 Nov 1:e0148022.  Abstract  
submitted by kickingbird at Nov, 4, 2022 from J Virol. 2022 Nov 1:e0148022 (via https://journals.asm.org/doi/10.1128/jvi.01480-22)
Influenza A viruses (FLUAV) cause respiratory diseases in many host species, including humans and pigs. The spillover of FLUAV between swine and humans has been a concern for both public health and the ...

Lei R, Tan TJC, Hernandez Garcia A, Wang Y, Diefen. Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase. Nat Commun. 2022 Oct 28;13(1):6443.  Abstract  
submitted by kickingbird at Oct, 30, 2022 from Nat Commun. 2022 Oct 28;13(1):6443 (via https://www.nature.com/articles/s41467-022-34060-8)
Neuraminidase (NA) of human influenza H3N2 virus has evolved rapidly and been accumulating mutations for more than half-century. However, biophysical constraints that govern the evolutionary trajectories ...

Isoda N, Onuma M, Hiono T, Sobolev I, Lim HY, Nabe. Detection of New H5N1 High Pathogenicity Avian Influenza Viruses in Winter 2021-2022 in the Far East, Which Are Genetically Close to Those in Europe. Viruses. 2022 Sep 30;14(10):2168.  Abstract  
submitted by kickingbird at Oct, 29, 2022 from Viruses. 2022 Sep 30;14(10):2168 (via https://www.mdpi.com/1999-4915/14/10/2168)
Many high pathogenicity avian influenza (HPAI) cases in wild birds due to H5N1 HPAI virus (HPAIV) infection were reported in northern Japan in the winter of 2021-2022. To investigate the epidemiology of ...

Karo-Karo D, Bodewes R, Restuadi R, Bossers A, Agu. Phylodynamics of Highly Pathogenic Avian Influenza A(H5N1) Virus Circulating in Indonesian Poultry. Viruses. 2022 Oct 8;14(10):2216.  Abstract  
submitted by kickingbird at Oct, 29, 2022 from Viruses. 2022 Oct 8;14(10):2216 (via https://www.mdpi.com/1999-4915/14/10/2216)
After its first detection in 1996, the highly pathogenic avian influenza A(H5Nx) virus has spread extensively worldwide. HPAIv A(H5N1) was first detected in Indonesia in 2003 and has been endemic in poultry ...

Wan Z, Kan Q, He D, Zhao Z, Gong J, Jiang W, Tang. Phylogeography and Biological Characterizations of H12 Influenza A Viruses. Viruses. 2022 Oct 13;14(10):2251.  Abstract  
submitted by kickingbird at Oct, 29, 2022 from Viruses. 2022 Oct 13;14(10):2251 (via https://www.mdpi.com/1999-4915/14/10/2251)
Influenza A virus (IAV) is widespread in wild bird reservoirs. Sixteen hemagglutinin subtypes are associated with wild waterfowl hosts; some subtypes are isolated infrequently, one of which is H12 IAV. ...

Hernández-Hernández VA, Higuera-Iglesias AL, Palma. A(H3N2) antigenic variation of influenza is associated with low vaccine efficacy in the early 2018 influenza season in Mexico City. Int J Infect Dis. 2022 Oct 22:S1201-9712(22)00567-.  Abstract  
submitted by kickingbird at Oct, 26, 2022 from Int J Infect Dis. 2022 Oct 22:S1201-9712(22)00567- (via https://www.ijidonline.com/article/S1201-9712(22)00567-7/ful)
Background: The evolution of influenza viruses causes a decrease in vaccine effectiveness (VE), requiring constant monitoring of mutations and readjustments to the recommended composition of influenza ...

Layton DS, Butler J, Stewart C, Stevens V, Payne J. H7N9 bearing a mutation in the nucleoprotein leads to increased pathology in chickens. Front Immunol. 2022 Oct 6;13:974210.  Abstract  
submitted by kickingbird at Oct, 25, 2022 from Front Immunol. 2022 Oct 6;13:974210 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.9742)
The zoonotic H7N9 avian influenza (AI) virus first emerged in 2013 as a low pathogenic (LPAI) strain, and has repeatedly caused human infection resulting in severe respiratory illness and a mortality of ...

Haney, J., Vijayakrishnan, S., Streetley, J. et al. Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles. Nat Microbiol (2022).  Abstract  
submitted by kickingbird at Oct, 25, 2022 from Nat Microbiol (2022) (via https://www.nature.com/articles/s41564-022-01242-5)
Interactions between respiratory viruses during infection affect transmission dynamics and clinical outcomes. To identify and characterize virus–virus interactions at the cellular level, we coinfected ...

Tian J, Li M, Li Y, Bai X, Song X, Zhao Z, Ge S, L. H3N8 subtype avian influenza virus originated from wild birds exhibited dual receptor-binding profiles. J Infect. 2022 Oct 20:S0163-4453(22)00622-3.  Abstract  
submitted by kickingbird at Oct, 24, 2022 from J Infect. 2022 Oct 20:S0163-4453(22)00622-3 (via https://www.journalofinfection.com/article/S0163-4453(22)006)
We present the phylogeny, receptor binding property, growth in mammal cells and pathogenicity in mammal model of H3N8 viruses, which were isolated from wild birds in China. The human receptor preference ...

Ye B, Shu L, Pang Y, Guo Y, Guo Y, Zong K, Chen C,. Repeated influenza vaccination induces similar immune protection as first-time vaccination but with differing immune responses. Influenza Other Respir Viruses. 2022 Oct 21.  Abstract  
submitted by kickingbird at Oct, 24, 2022 from Influenza Other Respir Viruses. 2022 Oct 21 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13060)
Background: Recent seasonal epidemics of influenza have been caused by human influenza A viruses of the H1N1 and H3N2 subtypes and influenza B viruses. Annual vaccination is recommended to prevent infection; ...

Qin T, Chen Y, Huangfu D, Yin Y, Miao X, Yin Y, Ch. PA-X Protein of H1N1 Subtype Influenza Virus Disables the Nasal Mucosal Dendritic Cells for Strengthening Virulence. Virulence. 2022 Oct 22.  Abstract  
submitted by kickingbird at Oct, 24, 2022 from Virulence. 2022 Oct 22 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2022.2)
PA-X protein arises from a ribosomal frameshift in the PA of influenza A virus (IAV). However, the immune regulatory effect of the PA-X protein of H1N1 viruses on the nasal mucosal system remains unclear. ...

Yang H, Dong Y, Bian Y, Xu N, Wu Y, Yang F, Du Y,. The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling. Nat Commun. 2022 Oct 21;13(1):6288.  Abstract  
submitted by kickingbird at Oct, 22, 2022 from Nat Commun. 2022 Oct 21;13(1):6288 (via https://www.nature.com/articles/s41467-022-33909-2)
Influenza A virus (IAV) polymerase protein PB2 has been shown to partially inhibit the host immune response by blocking the induction of interferons (IFNs). However, the IAV PB2 protein that regulates ...

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