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2026-2-1 17:25:28
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Cunningham MW, Brown J, Hardman R, Loerzel S, Klue. Outbreaks of Highly Pathogenic H5N1 Influenza A Virus infection in Black Vultures (Coragyps atratus), USA, 2022. J Wildl Dis. 2025 Jul 11.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from J Wildl Dis. 2025 Jul 11 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
Mortalities in Black Vultures (Coragyps atratus) caused by A/goose/Guangdong/1/1996 2.3.4.4b lineage highly pathogenic (HP) influenza A virus (IAV) H5N1 (HP H5N1) were detected in Florida, USA, on 14 February ...

Song Y, Zhang X, Ji J, Li L, Zhou Y, Ren G, Lv S,. Genetic characteristics analysis of influenza A(H1N1) virus in Jiaxing, China, in the postepidemic era. BMC Infect Dis. 2025 Jul 10;25(1):905.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from BMC Infect Dis. 2025 Jul 10;25(1):905 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
Background: Following the lifting of COVID-19 pandemic control measures, a progressive increase in influenza A virus activity, particularly the H1N1 subtype, has been observed in Jiaxing. This study systematically ...

Mosaad Z, Hagag NM, Elsayed MM, Mady WH, Zanaty AM. Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt. BMC Vet Res. 2025 Jul 11;21(1):455.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from BMC Vet Res. 2025 Jul 11;21(1):455 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
The current study aimed to investigate the genetic characterization and evolution of low pathogenic avian influenza virus H9N2 in Egypt. Ten H9N2 viruses were recently isolated from samples collected between ...

Neira V, Ariyama N, Castillo-Torres PN, Brito B, M. Genetic Characterization of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b, Antarctica, 2024. Emerg Infect Dis. 2025 Jul 9;31(8).  Abstract  
submitted by kickingbird at Jul, 11, 2025 from Emerg Infect Dis. 2025 Jul 9;31(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0186_article)
In 2024, we sequenced highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b genomes isolated from 5 brown skuas from James Ross Island, Antarctica. Phylogenetic analysis suggested the virus reached ...

Seo YR, Cho AY, Kim DJ, Si YJ, Jeong HS, Lee SW, S. Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024. Emerg Infect Dis. 2025 Jul 9;37(8).  Abstract  
submitted by kickingbird at Jul, 11, 2025 from Emerg Infect Dis. 2025 Jul 9;37(8) (via https://wwwnc.cdc.gov/eid/article/31/8/25-0373_article)
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023-March 2024. We isolated and sequenced 8 H5N1 ...

Biswas A, Eisfeld AJ, Guan L, Gu C, Wang T, Abozei. Susceptibility and shedding in Mx1+ and Mx1- female mice experimentally infected with dairy cattle A(H5N1) influenza viruses. EBioMedicine. 2025 Jul 8;118:105842.  Abstract  
submitted by kickingbird at Jul, 11, 2025 from EBioMedicine. 2025 Jul 8;118:105842 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) (HPAI H5N1) viruses have spread prolifically in dairy cattle in the US, resulting in dozens of human infections, some without well-established ...

Signore AV, Giacinti J, Jones MEB, Erdelyan CNG, M. Spatiotemporal reconstruction of the North American A(H5N1) outbreak reveals successive lineage replacements by descendant reassortants. Sci Adv. 2025 Jul 11;11(28):eadu4909.  Abstract  
submitted by kickingbird at Jul, 10, 2025 from Sci Adv. 2025 Jul 11;11(28):eadu4909 (via https://www.science.org/doi/10.1126/sciadv.adu4909)
The November 2021 introduction of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b into North America triggered a devastating outbreak, affecting more than 180 million domestic birds and spreading ...

Kandel S, Babujee L, Guan L, Dahn R, Pattinson D,. Phylogenetic analysis of H5N1 influenza viruses isolated from dairy cattle in Texas in December 2024. J Virol. 2025 Jul 8:e0058025.  Abstract  
submitted by kickingbird at Jul, 9, 2025 from J Virol. 2025 Jul 8:e0058025 (via https://journals.asm.org/doi/10.1128/jvi.00580-25)
Highly pathogenic avian influenza (HPAI) viruses of genotype B3.13 were first reported in dairy cattle in March 2024 and, by 4 March 2025, had infected at least 989 cattle herds in 17 states in the US ...

Hao M, Wu J, Ji L, Zhao Y, Zhang S, Guan Y, Li L,. Pathogenicity, transmissibility, and receptor binding of a human-isolated influenza A (H10N5) virus. mBio. 2025 Jul 8:e0073125.  Abstract  
submitted by kickingbird at Jul, 9, 2025 from mBio. 2025 Jul 8:e0073125 (via https://journals.asm.org/doi/10.1128/mbio.00731-25)
Recently, human infections with H10 influenza viruses, including H10N8 and H10N3, have been reported. In January 2024, a case of H10N5 and H3N2 co-infection was reported in Zhejiang Province, China, which ...

Chen, T., Ouyang, A., Zou, J. et al. Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane. Nat Commun 16, 6271 (2025).  Abstract  
submitted by kickingbird at Jul, 9, 2025 from Nat Commun 16, 6271 (2025) (via https://www.nature.com/articles/s41467-025-61587-3)
The molecular mechanisms underlying the transport of influenza A virus (IAV) membrane proteins to the cell surface remain largely unclear. In this study, siRNA screening identifies Rab27a as a critical ...

Neil Paprocki, Jeff Kidd, Courtney J. Conway. Increased Mortality Rates Caused by Highly Pathogenic Avian Influenza Virus in a Migratory Raptor. Ecology and Evolution.  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Ecology and Evolution (via https://onlinelibrary.wiley.com/doi/10.1002/ece3.71715)
Highly pathogenic avian influenza virus (HPAIV) has caused extensive mortalities in wild birds with a disproportionate impact on raptors since 2021. The population-level impact of HPAIV can be informed ...

Zhang, X., Wang, Y., Li, X. et al. Prevalence of Avian Influenza Viruses and Biomolecular Analysis of H9N2 Subtype in Live Poultry Markets from 2021 to 2023 in Changsha, China. Food Environ Virol 17, 38 (2025).  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Food Environ Virol 17, 38 (2025) (via https://link.springer.com/article/10.1007/s12560-025-09652-4)
Environmental monitoring of avian influenza virus (AIV) in live poultry markets (LPMs) is vital for health risk forewarning, and survey of AIV environmental prevalence and biomolecular analysis of keystone ...

Kristen Coleman, etc.,al. [preprint]Highly Pathogenic Avian Influenza A(H5N1) Outbreak Among House Cats: A Case Series Involving Oseltamivir Treatment. https://doi.org/10.21203/rs.3.rs-7015836/v1.  Abstract  
submitted by kickingbird at Jul, 7, 2025 from https://doi.org/10.21203/rs.3.rs-7015836/v1 (via https://www.researchsquare.com/article/rs-7015836/v1)
We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 ...

Young-Jae Si, etc.,al. First Detection of Clade 2.3.4.4b H5N1 Highly Pathogenic Avian Influenza Virus in a Wild Leopard cat (Prionailurus bengalensis) in South Korea. Front. Vet. Sci..  Abstract  
submitted by kickingbird at Jul, 7, 2025 from Front. Vet. Sci. (via https://www.frontiersin.org/journals/veterinary-science/arti)
The A/goose/Guangdong/1/1996 (Gs/GD) lineage of highly pathogenic avian influenza (HPAI) viruses initially identified in China in 1996 and have evolved over subsequent decades, characterized by accumulation ...

Danuta M Skowronski, etc.,al. [preprint]Neuraminidase imprinting and the age-related risk of zoonotic influenza. https://doi.org/10.1101/2025.07.03.25330844.  Abstract  
submitted by kickingbird at Jul, 6, 2025 from https://doi.org/10.1101/2025.07.03.25330844 (via https://www.medrxiv.org/content/10.1101/2025.07.03.25330844v)
Highly pathogenic avian influenza of the H5N1 subtype has shown recent unprecedented expansion in its geographic and host range, increasing the pandemic threat. The younger age of H5N1 versus H7N9 avian ...

Urban, C., Vrancken, B., Patrono, L.V. et al. An ancient influenza genome from Switzerland allows deeper insights into host adaptation during the 1918 flu pandemic in Europe. BMC Biol 23, 179 (2025).  Abstract  
submitted by kickingbird at Jul, 6, 2025 from BMC Biol 23, 179 (2025) (via https://link.springer.com/article/10.1186/s12915-025-02282-z)
BackgroundFrom 1918 to 1920, the largest influenza A virus (IAV) pandemic known to date spread globally causing between 20 to 100 million deaths. Historical records have captured critical aspects of the ...

Jianzhong Shi, Huihui Kong, Pengfei Cui, Guohua De. H5N1 virus invades the mammary glands of dairy cattle through “mouth-to-teat” transmission. National Science Review, 2025;, nwaf262.  Abstract  
submitted by kickingbird at Jul, 4, 2025 from National Science Review, 2025;, nwaf262 (via https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr)
H5N1 influenza outbreaks have been reported on more than 1,070 dairy farms across 17 states in the US. Damage to the mammary gland and high levels of virus in milk were common features of the infected ...

Flavio Cargnin Faccin, etc.,al. [preprint]Experimental infection and viral pathogenesis of a human isolate of H5N1 highly pathogenic avian influenza strain in Jersey cows. https://doi.org/10.21203/rs.3.rs-6915991/v1.  Abstract  
submitted by kickingbird at Jul, 4, 2025 from https://doi.org/10.21203/rs.3.rs-6915991/v1 (via https://www.researchsquare.com/article/rs-6915991/v1)
Highly pathogenic avian influenza H5N1 viruses have circulated globally since 1996. In recent years, clade 2.3.4.4b H5N1 viruses have crossed the species barrier into multiple species, including dairy ...

Durazzi, F., Koopmans, M.P.G., Fouchier, R.A.M. et. Language models learn to represent antigenic properties of human influenza A(H3) virus. Sci Rep 15, 21364 (2025).  Abstract  
submitted by kickingbird at Jul, 3, 2025 from Sci Rep 15, 21364 (2025) (via https://link.springer.com/article/10.1038/s41598-025-03275-2)
Given that influenza vaccine effectiveness depends on a good antigenic match between the vaccine and circulating viruses, it is important to assess the antigenic properties of newly emerging variants continuously. ...

Higgins D, Looker J, Sunnucks R, Carruthers J, Fin. Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humans. J R Soc Interface. 2025 Jul;22(228):20240910.  Abstract  
submitted by kickingbird at Jul, 3, 2025 from J R Soc Interface. 2025 Jul;22(228):20240910 (via https://royalsocietypublishing.org/doi/10.1098/rsif.2024.091)
Avian influenza A(H5N1) poses a public health risk due to its pandemic potential should the virus mutate to become human-to-human transmissible. To date, reported influenza A(H5N1) human cases have typically ...

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