Zhang X, Xu G, Wang C, Jiang M, et al.. Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations. J Gen Virol 2017 Jun 8. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Gen Virol 2017 Jun 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28597818/)
The H10 subtype of avian influenza viruses (AIVs) circulates globally in wild birds and poultry, and this subtype has been shown to be increasingly prevalent in China. Among the various H10 viruses, H10N7 ... Yamashita N, Yashiro M, Ogawa H, Namba H, et al. Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells. Biochem Biophys Res Commun 2017 May 30. Abstract
submitted by kickingbird at Jun, 13, 2017 from Biochem Biophys Res Commun 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28576495/)
Our previous analysis of gene expression profiles in the peripheral blood from patients with influenza A (H1N1) pdm09 pneumonia revealed elevated transcription levels of the vanin-1 (vascular non-inflammatory ... Wang BX, Brown EG, Fish EN. Residues F103 and M106 within the influenza A virus NS1 CPSF4-binding region regulate interferon-stimulated gene translation initiation. Virology 2017;508:170-179. Abstract
submitted by kickingbird at Jun, 5, 2017 from Virology 2017;508:170-179 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554059/)
Influenza A virus (IAV) non-structural protein 1 (NS1) suppresses host innate immune responses by inhibiting type I interferon (IFN) production. We provide evidence that residues F103 and M106 in the CPSF4-binding ... Bertran K, Balzli C, Lee DH, Suarez DL, et al. Protection of White Leghorn chickens by U.S. emergency H5 vaccination against clade 2.3.4.4 H5N2 high pathogenicity avian influenza virus. Vaccine 2017 May 26. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 26 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554502/)
During December 2014-June 2015, the U.S. experienced a high pathogenicity avian influenza (HPAI) outbreak caused by clade 2.3.4.4 H5Nx Goose/Guangdong lineage viruses with devastating consequences for ... Petiot E, Proust A, Traversier A, Durous L, et al. Influenza viruses production: Evaluation of a novel avian cell line DuckCelt-T17. Vaccine 2017 May 29. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28571695/)
The influenza vaccine manufacturing industry is looking for production cell lines that are easily scalable, highly permissive to multiple viruses, and more effective in term of viral productivity. One ... Yu Y, Zhang X, Zhao B, Sun Y, et al. A Sandwich ELISA for the Detection of Neuraminidase of Avian Influenza A(H7N9) Virus. J Virol Methods 2017 May 24.. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Virol Methods 2017 May 24. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28551451/)
Although exhibiting no or low virulence in poultry, avian influenza virus H7N9 has caused around 1,200 confirmed human infections in China with a case-fatality rate of 30% since 2013. A highly pathogenic ... Granados A, Petrich A, McGeer A, Gubbay JB, et al. Measuring influenza RNA quantity after prolonged storage or multiple freeze/thaw cycles. J Virol Methods 2017;247:45-50. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Virol Methods 2017;247:45-50 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28572040/)
In this study, we aim to determine what effects prolonged storage and repeated freeze/thaw cycles have on the stability of influenza A(H1N1)pdm09 (influenza A/H1N1)RNA. Cloned influenza A/H1N1 RNA transcripts ... Lee ACY, To KKW, Zhu H, Chu H, et al. Avian influenza virus A H7N9 infects multiple mononuclear cell types in peripheral blood and induces dysregulated cytokine responses and apoptosis in infected monocytes. J Gen Virol 2017 May 30. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Gen Virol 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28555541/)
Most patients with avian influenza A H7N9 virus (H7N9) infection suffer from severe illness, accompanied by dysregulated cytokine/chemokine response, delayed viral clearance and impaired neutralizing antibody ... Baratelli M, Pedersen LE, Trebbien R, Larsen LE, e. Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs. J Gen Virol 2017 May 30. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Gen Virol 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28555545/)
Heterologous protection against swine influenza viruses (SwIVs) of different lineages is an important concern for the pig industry. Cross-protection between 'avian-like' H1N1 and 2009 pandemic H1N1 lineages ... Giarola-Silva S, Coelho-Dos-Reis JGA, Mourao MM, C. Distinct patterns of cellular immune response elicited by influenza non-adjuvanted and AS03-adjuvanted monovalent H1N1(pdm09) vaccine. Antiviral Res 2017;144:70-82.. Abstract
submitted by kickingbird at Jun, 5, 2017 from Antiviral Res 2017;144:70-82. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28549970/)
The study aimed at identifying biomarkers of immune response elicited by non-adjuvanted-(NAV) and adjuvanted-(AV) H1N1(pdm09) vaccines. The results showed that despite both vaccines elicited similar levels ... Lin CY, Chia MY, Chen PL, Yeh CT, et al.. Assessment of pathogenicity and antigenicity of American lineage influenza H5N2 viruses in Taiwan. Virology 2017;508:159-163. Abstract
submitted by kickingbird at May, 29, 2017 from Virology 2017;508:159-163 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28549236/)
During December 2003 and March 2004, large scale epidemics of low-pathogenic avian influenza (LPAI) H5N2 occurred in poultry farms in central and southern Taiwan. Based on genomic analysis, these H5N2 ... Randolph AG, Yip WK, Allen EK, Rosenberger CM, et. Evaluation of IFITM3 rs12252 Association with Severe Pediatric Influenza Infection. J Infect Dis 2017 May 20. Abstract
submitted by kickingbird at May, 29, 2017 from J Infect Dis 2017 May 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28531322/)
Background: Interferon inducible transmembrane protein 3 (IFITM3) restricts endocytic fusion of influenza virus. IFITM3 rs12252_C, a putative alternate splice site, has been associated with influenza severity ... Hara K, Kashiwagi T, Hamada N, Watanabe H, et al. Basic amino acids in the N-terminal half of the PB2 subunit of influenza virus RNA polymerase are involved in both transcription and replication. J Gen Virol 2017 May 22.. Abstract
submitted by kickingbird at May, 29, 2017 from J Gen Virol 2017 May 22. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28530165/)
The PB2 subunit of influenza virus RNA polymerase is known to be involved in the initiation of transcription of the virus genome via cap binding. However, other specific roles of PB2 for viral RNA synthesis ... Zhao D, Liang L, Wang S, Nakao T, et al. Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response. J Virol 2017;91. Abstract
submitted by kickingbird at May, 22, 2017 from J Virol 2017;91 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28100622/)
The highly pathogenic avian influenza (HPAI) H5N1 viruses continue to circulate in nature and threaten public health. Although several viral determinants and host factors that influence the virulence of ... Pereira CF, Read EKC, Wise HM, Amorim MJ, et al. The influenza A virus NS1 protein promotes efficient nuclear export of unspliced viral M1 mRNA. Virol 2017 May 17. pii: JVI.00528-17. Abstract
submitted by kickingbird at May, 22, 2017 from Virol 2017 May 17. pii: JVI.00528-17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28515301/)
Influenza A virus mRNAs are transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before being exported to the cytoplasm for translation. Segment 7 produces two major transcripts: an ... Lee N, Cao B, Ke C, Lu H, et al. IFITM3, TLR3, and CD55 Genes SNPs and Cumulative Ge-netic Risks for Severe Outcomes in Chinese Patients with H7N9 / H1N1pdm09 Influenza. J Infect Dis 2017 May 16. Abstract
submitted by kickingbird at May, 22, 2017 from J Infect Dis 2017 May 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28510725/)
Background: We examined associations between SNPs (single-nucleotide-polymorphisms) of IFITM3, TLR3, and CD55 genes and influenza clinical outcomes in Chinese patients. Methods: A multicenter-study was ... Root JJ, Shriner SA, Ellis JW, VanDalen KK, et al. Transmission of H6N2 wild bird-origin influenza A virus among multiple bird species in a stacked-cage setting. Arch Virol 2017 May 16. Abstract
submitted by kickingbird at May, 22, 2017 from Arch Virol 2017 May 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28508987/)
Live bird markets are common in certain regions of the U.S. and in other regions of the world. We experimentally tested the ability of a wild bird influenza A virus to transmit from index animals to na?ve ... Liu S, Zhang L, Yao Z, Xing L, et al. In vitro and in vivo characterization of a novel H1N1/2009 influenza virus reassortant with an NS gene from a highly pathogenic H5N1 virus, isolated from a human. Arch Virol 2017 May 18. Abstract
submitted by kickingbird at May, 22, 2017 from Arch Virol 2017 May 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28523521/)
The triple-reassortant H1N1/2009 influenza A virus, which caused the first influenza pandemic of the 21(st) century, is generally associated with mild disease and a relatively low mortality rate comparable ... JA Besler,etc.,al. A novel A(H7N2) influenza virus isolated from a veterinarian caring for cats in a New York City animal shelter causes mild disease and transmits poorly in the ferret model. J Virol May 17. Abstract
submitted by kickingbird at May, 19, 2017 from J Virol May 17 (via http://jvi.asm.org/content/early/2017/05/12/JVI.00672-17.abs)
In December 2016, a low pathogenic avian influenza (LPAI) A(H7N2) virus was identified as the causative source of an outbreak in a cat shelter in New York City, which subsequently spread to multiple shelters ... Bahl K. et al.. Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses. Mol Ther. 2017 Apr 11. pii: S1525-0016(17)30156-9.. Abstract
submitted by kickingbird at May, 15, 2017 from Mol Ther. 2017 Apr 11. pii: S1525-0016(17)30156-9. (via http://www.cell.com/molecular-therapy-family/molecular-thera)
Recently, the World Health Organization confirmed 120 new human cases of avian H7N9 influenza in China resulting in 37 deaths, highlighting the concern for a potential pandemic and the need for an ... 6898 items, 20/Page, Page[243/345][|<<] [|<] [241] [242] [243] [244] [245] [246] [247] [248] [249] [250] [>|] [>>|] |
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