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2024-3-29 17:59:56
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De Clercq E.. Influenza virus inhibitors available for the chemotherapy and/or chemoprophylaxis of influenza virus infections. Verh K Acad Geneeskd Belg. 2006;68(2):121-37.  Abstract  
submitted by wanglh at Jun, 30, 2006 from Verh K Acad Geneeskd Belg. 2006;68(2):121-37 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
There are, at present, only three (classes of) compounds that could be considered for the chemotherapy and -prophylaxis of influenza virus infections: ribavirin, amantadine/rimantadine and the neuraminidase ...

Monto AS, McKimm-Breschkin JL, Macken C, Hampson A. Detection of Influenza Viruses Resistant to Neuraminidase Inhibitors in Global Surveillance during the First 3 Years of Their Use. Antimicrob Agents Chemother. 2006 Jul;50(7):2395-4.  Abstract  
submitted by wanglh at Jun, 30, 2006 from Antimicrob Agents Chemother. 2006 Jul;50(7):2395-4 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Emergence of influenza viruses with reduced susceptibility to neuraminidase inhibitors (NAIs) develops at a low level following drug treatment, and person-to-person transmission of resistant virus has ...

Edwards et al. Antigenic characteristics of recent avian influenza A H5N1 viruses isolated from humans [Feb 2003 case, Hong Kong ex Fujian]. Internl Congress Series.  Abstract  
submitted by Joe Dudley at Jun, 28, 2006 from Internl Congress Series (via http://cmbi.bjmu.edu.cn/news/report/2005/flu/4.pdf)
Edwards, L.E., D.C. Nguyen, X. Lu, H. Hall, A. Balish, J.E. Mabry, W. Lim,N.J. Cox, A. Klimov, and J.M. Katz (2004). Antigenic characteristics ofrecent avian influenza A H5N1 viruses isolated from humans. ...

GUO Xiao-ling; CUI Hong; WANG Yu; ZHANG Guo-gua. Expression of H5N1HA Gene of an Avian Influenza Virus in Tobacco. Journal of Xiamen Univeristy(Natural Science).  Abstract  
submitted by wanglh at Jun, 26, 2006 from Journal of Xiamen Univeristy(Natural Science)
H5N1,a novel avian influenza virus,can infect human directly.In this study,the DNA fragment of H5N1 avian influenza HA gene,antigen determinant,was transferred into tobacco(Nicotiana tabacum cv.) via leaf-discs ...

LI Ren-qing; LU Ning; DENG Yao; WANG Wen-ling; XIN. Cross protective immunity against influenza A virus between subtypes induced by influenza polymerase protein PB1 in mice. Chinese Journal of Microbiology and Immunology.  Abstract  
submitted by wanglh at Jun, 26, 2006 from Chinese Journal of Microbiology and Immunology
To investigate the possibility of the influenza RNA polymerase proteins PB2 and PBl served as the alternative antigens of the experimental influenza vaccine. Methods The replicative DNA vaccines encoding ...

ZHAO Li; WANG Wei-li; ZHOU Yu; LIU Ming. Cloning and Analysis of NA Gene of a Pigeon H5N1 Influenza A Virus. Journal of Jilin Agricultural University.  Abstract  
submitted by kickingbird at Jun, 17, 2006 from Journal of Jilin Agricultural University
Total RNA of influenza A virus(H5N1)was isolated by treatment of aliquots of the virus with TRIAZOL.Full-length NA cDNA was prepared by RT-PCR and cloned into pMDT-18 vector.Sequence analysis proved that ...

Elena A. Govorkova et al. Immunization with Reverse-Genetics–Produced H5N1 Influenza Vaccine Protects Ferrets against Homologous and Heterologous Challenge. The Journal of Infectious Diseases.  Abstract  
submitted by TenHoursEast at Jun, 15, 2006 from The Journal of Infectious Diseases (via http://www.journals.uchicago.edu/JID/journal/issues/v194n2/3)
There is an accompanying commentary http://www.journals.uchicago.edu/JID/journal/issues/v194n2/36564/36564.htmlfrom Dr Alan Hampson, (Australian Influenza Specialist Group, Richmond, and School of Applied ...

Areechokchai et al. Investigation of Avian Influenza (H5N1) Outbreak in Humans --- Thailand, 2004. Morbidity Mortality Weekly Review.  Full Text  
submitted by Joe Dudley at Jun, 14, 2006 from Morbidity Mortality Weekly Review (via http://www.cdc.gov/mmwr/preview/mmwrhtml/su5501a2.htm)
Darin Areechokchai,1 C. Jiraphongsa,1 Y. Laosiritaworn,1 W. Hanshaoworakul,1 M. O'Reilly2 1Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand 2Thailand ...

Hui EK, Smee DF, Wong MH, Nayak DP.. Mutations in Influenza Virus M1 CCHH, the Putative Zinc Finger Motif, Cause Attenuation in Mice and Protect Mice against Lethal Influenza Virus Infection. J Virol. 2006 Jun;80(12):5697-707.  Abstract  
submitted by kickingbird at Jun, 9, 2006 from J Virol. 2006 Jun;80(12):5697-707 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Mutations in CCHH, the putative zinc finger motif, apparently do not play an important role in virus replication in MDCK cells in culture (E. K.-W. Hui, K. Ralston, A. K. Judd, and D. P. Nayak, J. Gen. ...

Chen H, Li Y, Li Z, Shi J, Shinya K, Deng G, Qi Q,. Properties and Dissemination of H5N1 Viruses Isolated during an Influenza Outbreak in Migratory Waterfowl in Western China. J Virol. 2006 Jun;80(12):5976-83.  Abstract  
submitted by kickingbird at Jun, 9, 2006 from J Virol. 2006 Jun;80(12):5976-83 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
H5N1 influenza A viruses are widely distributed among poultry in Asia, but until recently, only a limited number of wild birds were affected. During late April through June 2005, an outbreak of H5N1 virus ...

Li M, Li ZN, Yao Q, Yang C, Steinhauer DA, Compans. Murine leukemia virus R Peptide inhibits influenza virus hemagglutinin-induced membrane fusion. J Virol. 2006 Jun;80(12):6106-14..  Abstract  
submitted by kickingbird at Jun, 9, 2006 from J Virol. 2006 Jun;80(12):6106-14. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The cytoplasmic tail of the murine leukemia virus (MuLV) envelope (Env) protein is known to play an important role in regulating viral fusion activity. Upon removal of the C-terminal 16 amino acids, designated ...

Hurt AC, Hansbro PM, Selleck P, Olsen B, Minton C. Isolation of avian influenza viruses from two different transhemispheric migratory shorebird species in Australia. Arch Virol. 2006 May 26.  Abstract  
submitted by kickingbird at Jun, 9, 2006 from Arch Virol. 2006 May 26
Shorebirds on their southerly migration from Siberia to Australia, may pass through Asian regions currently experiencing outbreaks of highly pathogenic H5N1 influenza. To test for the presence of avian ...

Daum LT, Canas LC, Klimov AI, Shaw MW, Gibbons RV. Molecular analysis of isolates from influenza B outbreaks in the U.S. and Nepal, 2005. Arch Virol. 2006 May 31.  Abstract  
submitted by kickingbird at Jun, 9, 2006 from Arch Virol. 2006 May 31
Currently circulating influenza B viruses can be divided into two antigenically and genetically distinct lineages referred to by their respective prototype strains, B/Yamagata/16/88 and B/Victoria/2/87, ...

CHANG S, ZHENG XY, YANG ST, ZOU XT, Ding Z, XIA XZ. Determining the Distribution and Contents of High Pathogenic Avian influenza virus from Tiger in Mice. Progress in Veterinary Medicine 2006 05.  Abstract  
submitted by kickingbird at Jun, 8, 2006 from Progress in Veterinary Medicine 2006 05
With the dilution of 10~-3 from the third generation of allantoic fluid in embryonated eggs infected by H5N1 high pathogenic avian influenza virus A/Tiger/Harbin/01/2003 strain which was isolated and verified ...

WANG Wei-li, ZHOU Yu, ZHAO Li, LIU Ming, QIAN AD. Sequence Analysis of HA Gene of An Avian Influenza Virus(H9N2) Isolate. Journal of Jilin Agricultural University.  Abstract  
submitted by kickingbird at Jun, 6, 2006 from Journal of Jilin Agricultural University
The cDNA of HA gene of H9N2 avian influenza isolate was amplified,cloned and then sequenced.The result of its sequence analysis shows that cDNA of HA gene is composed of(1 683 bp) nucleotides,encoding ...

LI Yao-Chen, ZHAO Zhi-Gang, LI Kang-Sheng. RNA interference mediated inhibition of influenza virus NP and PA gene expressions and multiplication in MDCK cells. Journal of the Fourth Military Medical University.  Abstract  
submitted by kickingbird at Jun, 6, 2006 from Journal of the Fourth Military Medical University
AIM: To apply the small interfering RNAs targeting NP or/and PA gene of influenza virus to inhibit the expression of NP or/and PA and multiplication of influenza virus in Madin-Darby canine kidney (MDCK) ...

Ernst WA, Kim HJ, Tumpey TM, Jansen AD, Tai W, Cra. Protection against H1, H5, H6 and H9 influenza A infection with liposomal matrix 2 epitope vaccines. Vaccine. 2006 May 2.  Abstract [Primary member] 
submitted by kickingbird at May, 30, 2006 from Vaccine. 2006 May 2 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
The recent emergence of multiple avian influenza A subtypes that cause human disease (i.e., H5N1, H9N2 and H7N7), coupled with the fear that one of these strains might precipitate a new pandemic, underscores ...

Bornholdt ZA, Prasad BV. X-ray structure of influenza virus NS1 effector domain. Nat Struct Mol Biol. 2006 May 21.  Abstract  
submitted by kickingbird at May, 30, 2006 from Nat Struct Mol Biol. 2006 May 21 (via http://www.nature.com/nsmb/journal/vaop/ncurrent/abs/nsmb109)
The nonstructural protein NS1 of influenza virus is an antagonist of host immune responses and is implicated in virulence. It has two domains, an N-terminal double-stranded RNA-binding domain (RBD) and ...

Park MS, Steel J, Garcia-Sastre A, Swayne D, Pales. Engineered viral vaccine constructs with dual specificity: Avian influenza and Newcastle disease. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8203.  Full Text [Primary member] 
submitted by kickingbird at May, 30, 2006 from Proc Natl Acad Sci U S A. 2006 May 23;103(21):8203 (via http://www.pnas.org/cgi/content/full/103/21/8203)
Avian influenza viruses of the H5 and H7 hemagglutinin subtypes, and Newcastle disease virus (NDV), are important pathogens in poultry worldwide. Specifically, the highly pathogenic H5N1 avian influenza ...

Veits J, Wiesner D, Fuchs W, Hoffmann B, Granzow H. Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8197.  Full Text [Primary member] 
submitted by kickingbird at May, 30, 2006 from Proc Natl Acad Sci U S A. 2006 May 23;103(21):8197 (via http://www.pnas.org/cgi/content/full/103/21/8197)
Newcastle disease virus (NDV)-expressing avian influenza virus (AIV) hemagglutinin (HA) of subtype H5 was constructed by reverse genetics. A cloned full-length copy of the genome of the lentogenic NDV ...

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