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2025-12-5 19:03:25
Article

Nacken, W., Mayr, J., Schreiber, A. et al. Influenza A virus NS1 suppresses nuclear speckles promoted gene expression by inhibition of transcription. npj Viruses 3, 46 (2025).  Abstract  
submitted by kickingbird at Jun, 2, 2025 from npj Viruses 3, 46 (2025) (via https://www.nature.com/articles/s44298-025-00124-x)
IAV-NS1 proteins that interact with Cleavage and polyadenylation specific factor 30 are known to inhibit host gene expression. Here we report that in both transfection and infection experiments, a strong ...

Lu, X., Zhao, S., Liu, A. et al. Nonlinear Enhanced Prediction of Influenza-Like Illness Using Seasonal-Trend Decomposition and Temporal Dependency. SIViP 19, 681 (2025).  Abstract  
submitted by kickingbird at Jun, 2, 2025 from SIViP 19, 681 (2025) (via https://link.springer.com/article/10.1007/s11760-025-04280-8)
Influenza-like illness (ILI) is a common respiratory infectious disease that puts significant strain on medical resources and leads to numerous fatalities worldwide. Accurate prediction of ILI incidence ...

Norikazu Isoda, etc.,al. Dynamics of high pathogenicity avian influenza virus infection with multiple introductions in a crow flock in an urban park in Hokkaido, Japan. Comparative Immunology, Microbiology and Infectiou.  Abstract  
submitted by kickingbird at Jun, 2, 2025 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
Since 2021, high pathogenicity avian influenza viruses (HPAIVs) of the H5N1 clade 2.3.4.4b has been circulating globally, not only in domestic poultry but also in wild birds, both migratory and resident ...

Viviani L, Vecchio R, Pariani E, Sandri L, Binda S. Wastewater-based epidemiology of influenza viruses: a systematic review. Sci Total Environ. 2025 May 30;986:179706.  Abstract  
submitted by kickingbird at Jun, 1, 2025 from Sci Total Environ. 2025 May 30;986:179706 (via https://www.sciencedirect.com/science/article/pii/S004896972)
Introduction: Wastewater-based epidemiology (WBE) has emerged as a valuable public health tool for monitoring the circulation of many pathogens, including influenza viruses (IVs). The general aim of this ...

Lombard J, Stenkamp-Strahm C, McCluskey B, Melody. Evidence of Viremia in Dairy Cows Naturally Infected with Influenza A Virus, California, USA. Emerg Infect Dis. 2025 Jul.  Abstract  
submitted by kickingbird at May, 31, 2025 from Emerg Infect Dis. 2025 Jul (via https://wwwnc.cdc.gov/eid/article/31/7/25-0134_article)
We confirmed influenza A virus (IAV) by PCR in serum from 18 cows on 3 affected dairy farms in California, USA. Our findings indicate the presence of viremia and might help explain IAV transmission dynamics ...

Qiong Zhang, etc.,al. [preprint]Preclinical Evaluation of an mRNA Vaccine Developed from the First Human Isolate of Bovine H5N1. https://doi.org/10.21203/rs.3.rs-6758243/v1.  Abstract  
submitted by kickingbird at May, 31, 2025 from https://doi.org/10.21203/rs.3.rs-6758243/v1 (via https://www.researchsquare.com/article/rs-6758243/v1)
Given the ongoing global health threat posed by the zoonotic emergence of H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI), there is an urgent need for the rapid development of effective vaccines. ...

Hassan M, Kaifer B, Christian T, Quaas XT, Mueller. First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models. Front Cell Infect Microbiol. 2025 May 15;15:159695.  Abstract  
submitted by kickingbird at May, 30, 2025 from Front Cell Infect Microbiol. 2025 May 15;15:159695 (via https://www.frontiersin.org/journals/cellular-and-infection-)
The human respiratory system is vulnerable to viral infections. The influenza virus family alone accounts for one billion reported cases annually, some of which are severe and can be fatal. Among these, ...

Nabeshima, K., Asakura, S., Sakoda, Y. et al. Novel host factors associated with resistance to highly pathogenic avian influenza in wild birds inferred from primary cell culture. Sci Rep 15, 18809 (2025).  Abstract  
submitted by kickingbird at May, 30, 2025 from Sci Rep 15, 18809 (2025) (via https://www.nature.com/articles/s41598-025-01316-4)
Bird species differ in the sensitivity to the highly pathogenic avian influenza virus (HPAIV). Here, we infected fibroblasts from 11 bird species with the H5N1 HPAIV strain A/chicken/Yamaguchi/7/2004. ...

Cao L, Wang T, Ren P, Cheng C, Mao H, Hui X, Lin X. Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication. Microbiol Spectr 0:e03120-24.  Abstract  
submitted by kickingbird at May, 30, 2025 from Microbiol Spectr 0:e03120-24 (via https://journals.asm.org/doi/10.1128/spectrum.03120-24)
The H5N6 avian influenza virus, a highly pathogenic strain, poses a significant threat to poultry production and public health. The RNA-dependent RNA polymerase (comprising PB1, PB2, and PA proteins) and ...

Cong He, etc.,al. A G219A hemagglutinin substitution increases pathogenicity and viral replication of Eurasian avian-like H1N1 swine influenza viruses. Veterinary Microbiology.  Abstract  
submitted by kickingbird at May, 30, 2025 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The Eurasian avian-like swine (EA) H1N1 virus has been widely prevalent in the Chinese swine population and has caused infections in human. However, knowledge regarding its pathogenic mechanisms remains ...

Seiler P, Kaplan BS, Brice DC, Duan S, Li L, McGar. Altered germinal center responses in mice vaccinated with highly pathogenic avian influenza A(H5N1) virus. Vaccine. 2025 May 27;60:127311.  Abstract  
submitted by kickingbird at May, 30, 2025 from Vaccine. 2025 May 27;60:127311 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Highly pathogenic avian influenza (HPAI) H5N1 virus vaccines typically yield lower neutralizing antibody titers in animals than influenza A virus (IAV) vaccines derived from other viral subtypes. To understand ...

Jenna Schafers, etc.,al. [preprint]Stability of influenza viruses in the milk of cows and sheep. https://doi.org/10.1101/2025.05.28.25328508.  Abstract  
submitted by kickingbird at May, 29, 2025 from https://doi.org/10.1101/2025.05.28.25328508 (via https://www.medrxiv.org/content/10.1101/2025.05.28.25328508v)
In late 2023, H5N1 high pathogenicity avian influenza (HPAIV) started circulating in dairy cattle in the USA. High viral titres were detected in milk from infected cows, raising concerns about onwards ...

Goldin, K., van Tol, S., Johnson, R.C. et al. Enhanced neurotropism of bovine H5N1 compared to the Vietnam H5N1 isolate in C57BL/6J mice. npj Viruses 3, 43 (2025).  Abstract  
submitted by kickingbird at May, 29, 2025 from npj Viruses 3, 43 (2025) (via https://www.nature.com/articles/s44298-025-00121-0)
In this study, we investigated differences in tissue tropism of two HPAI H5N1 strains, the isolate A/Vietnam/1203/2004 (VN1203) isolated from a fatal human case in 2004 and the bovine isolate A/Bovine/Ohio/B24osu-342/2024 ...

Maeve Louise Farrell, etc.,al. [preprint]Avian Influenza in Ireland: A Spatiotemporal, Subtype, and Host-Based Analysis (1983-2024). https://doi.org/10.1101/2025.05.26.656175.  Abstract  
submitted by kickingbird at May, 28, 2025 from https://doi.org/10.1101/2025.05.26.656175 (via https://www.biorxiv.org/content/10.1101/2025.05.26.656175v1)
Avian influenza virus (AIV) is a significant global concern, causing widespread mortality in wild birds, domestic poultry and most recently wild and domestic mammals. This study presents a retrospective ...

Ralph E.V. Vanstreels, etc.,al. [preprint]Novel Highly Pathogenic Avian Influenza (A)H5N1 Triple Reassortant in Argentina, 2025. https://doi.org/10.1101/2025.05.23.655175.  Abstract  
submitted by kickingbird at May, 28, 2025 from https://doi.org/10.1101/2025.05.23.655175 (via https://www.biorxiv.org/content/10.1101/2025.05.23.655175v1)
Genomic sequencing of re-emerging highly pathogenic avian influenza A(H5N1) virus detected in Argentina in February 2025 revealed novel triple-reassortant viruses containing gene segments from Eurasian ...

Muawan, L., Takada, K., Yoshimoto, S. et al. Characterization of A(H1N1)pdm09 influenza viruses isolated between 2016 and 2019. Npj Viruses. 2025 May 22;3(1):42.  Abstract  
submitted by kickingbird at May, 25, 2025 from Npj Viruses. 2025 May 22;3(1):42 (via https://www.nature.com/articles/s44298-025-00126-9)
The A(H1N1)pdm09 virus, which caused the 2009 influenza pandemic, has continued to circulate in humans for over a decade. Understanding its biological properties is crucial for effective surveillance, ...

Grim R?mo, etc.,al. [preprint]Highly Pathogenic Avian Influenza A(H5N1) Caused Mass Death among Black-legged Kittiwakes (Rissa tridactyla) in Norway, 2023. https://doi.org/10.1101/2025.05.23.655725.  Abstract  
submitted by kickingbird at May, 25, 2025 from https://doi.org/10.1101/2025.05.23.655725 (via https://www.biorxiv.org/content/10.1101/2025.05.23.655725v1)
In 2023, highly pathogenic avian influenza (HPAI) heavily affected gulls in Europe. In July, a mass mortality event was reported in the Black-legged Kittiwake (Rissa tridactyla) breeding colony at Ekker?y ...

AL-Eitan LN, Almahdawi DL, Khair IY. Phylogenetic Analysis and Spread of HPAI H5N1 in Middle Eastern Countries Based on Hemagglutinin and Neuraminidase Gene Sequences. Viruses. 2025; 17(5):734.  Abstract  
submitted by kickingbird at May, 23, 2025 from Viruses. 2025; 17(5):734 (via https://www.mdpi.com/1999-4915/17/5/734)
Highly pathogenic avian influenza (HPAI) A/H5N1 viruses threaten animal and human health worldwide. The first documented cases in the Middle East were reported in 2005; however, despite extensive phylogenetic ...

Bellido-Martín, B., Rijnink, W.F., Iervolino, M. e. Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses. Nat Rev Microbiol (2025).  Abstract  
submitted by kickingbird at May, 23, 2025 from Nat Rev Microbiol (2025) (via https://link.springer.com/article/10.1038/s41579-025-01189-4)
Since their first detection in 1996, highly pathogenic avian influenza viruses with H5 haemagglutinin of the A/Goose/Guangdong/1/1996 (Gs/Gd) lineage have caused outbreaks in domestic and wild animals ...

Allen JD, Medina JM, Thomas MH, Lynch A, Nelson R,. H3 hemagglutinin proteins optimized for 2018 to 2022 elicit neutralizing antibodies across panels of modern influenza A(H3N2) viruses. J Immunol. 2025 May 21:vkaf092.  Abstract  
submitted by kickingbird at May, 23, 2025 from J Immunol. 2025 May 21:vkaf092 (via https://academic.oup.com/jimmunol/advance-article-abstract/d)
Influenza A(H3N2) viruses are currently evolving faster than any other subtype of seasonal influenza. As a result, vaccine efficacy can vary widely from one year to the next, and the wild-type antigens ...

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