Alexander L Jaffe, etc.,al. [preprint]Divergent avian strains drive an off-season influenza A peak in municipal wastewater. https://doi.org/10.64898/2026.04.02.26350079. Abstract
submitted by kickingbird at Apr, 6, 2026 from https://doi.org/10.64898/2026.04.02.26350079 (via https://www.medrxiv.org/content/10.64898/2026.04.02.26350079)
Wastewater sequencing is an increasingly valuable tool in tracking the spread of infectious disease agents across space and time in areas of dense human settlement. Among pathogens that can be readily ... Liu J, Huang J, Wang Q, Wei Y, Han L, Li X, Lei C,. Tyrosine kinase LYN restricts the replication and virulence of influenza A virus by directly phosphorylating viral nucleoprotein. mBio 0:e03759-25. Abstract
submitted by kickingbird at Apr, 5, 2026 from mBio 0:e03759-25 (via https://journals.asm.org/doi/10.1128/mbio.03759-25)
The continuous antigenic shift and drift of influenza A virus (IAV) result in the emergence of novel strains and drug resistance. Accordingly, it is urgent to develop novel antiviral drugs that target ... Hui KPY, Ho JCW, Ng KC, Webby RJ, Peiris M, Nichol. Tropism and Replication Competence of Cattle Influenza A(H5N1) Genotype B3.13 Virus in Human Bronchus and Lung Tissue. Emerg Infect Dis. 2026 May;32(5). Abstract
submitted by kickingbird at Apr, 4, 2026 from Emerg Infect Dis. 2026 May;32(5) (via https://wwwnc.cdc.gov/eid/article/32/5/25-1926_article)
In 2024, influenza A(H5N1) genotype B3.13 viruses emerged from cattle and caused mild spillover infections in humans. Using human bronchus and lung tissue, we evaluated tropism, replication, and pathogenesis ... Chaulagain S, Creisher P, Park HS, Liu J, Gay LC,. [preprint]Influenza B virus suppression of Chromosome Y-linked genes increases pulmonary virus replication and disease severity in male mice. https://doi.org/10.21203/rs.3.rs-9066058/v1. Abstract
submitted by kickingbird at Apr, 4, 2026 from https://doi.org/10.21203/rs.3.rs-9066058/v1 (via https://www.researchsquare.com/article/rs-9066058/v1)
Influenza B viruses (IBV) are transmitted among humans, with disease being worse in men than women. C57BL/6 male and female mice were inoculated with Victoria lineage B/Brisbane/60/2008 containing a PB2 ... William W Zou, etc.,al. [preprint]Predicting highly pathogenic avian influenza H5N1 outbreak risk using extreme weather and bird migration data in machine learning models. https://doi.org/10.64898/2026.03.30.26349797. Abstract
submitted by kickingbird at Apr, 3, 2026 from https://doi.org/10.64898/2026.03.30.26349797 (via https://www.medrxiv.org/content/10.64898/2026.03.30.26349797)
Background. Climate change is intensifying extreme weather events (EWEs) with potentially profound consequences for zoonotic disease dynamics, yet the mechanisms linking EWEs to highly pathogenic avian ... Emily A. McNair, etc.,al. [preprint]Characterizing Oseltamivir Use among Community-Dwelling Patients Diagnosed with Influenza Virus Infection, 2023-2025. https://doi.org/10.64898/2026.03.27.26349417. Abstract
submitted by kickingbird at Apr, 3, 2026 from https://doi.org/10.64898/2026.03.27.26349417 (via https://www.medrxiv.org/content/10.64898/2026.03.27.26349417)
Background Oseltamivir is an antiviral medication for influenza that can reduce the duration of symptoms and may lower the risk of some complications. Recommendations for use of oseltamivir include in ... Camille Lebarbenchon, etc.,al. [preprint]Brown and Lesser noddies as epidemiological reservoirs and sentinels of avian influenza virus in the South-western Indian Ocean. https://doi.org/10.64898/2026.03.31.715511. Abstract
submitted by kickingbird at Apr, 3, 2026 from https://doi.org/10.64898/2026.03.31.715511 (via https://www.biorxiv.org/content/10.64898/2026.03.31.715511v1)
Avian influenza virus (AIV) epidemiology is well documented in temperate regions but remains poorly understood in isolated ecosystems like tropical oceanic islands. On these islands, seabirds nest in dense ... Jonathan E. Pekar, etc.,al. [preprint]The emergence and molecular evolution of H5N1 influenza viruses in United States dairy cattle. https://doi.org/10.64898/2026.03.30.713641. Abstract
submitted by kickingbird at Apr, 3, 2026 from https://doi.org/10.64898/2026.03.30.713641 (via https://www.biorxiv.org/content/10.64898/2026.03.30.713641v1)
Prior to 2024, highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses circulated predominantly in wild birds and poultry. In 2024 and 2025, 2.3.4.4b genotypes B3.13 and D1.1 were detected in United ... Rajesh T. Yadav, etc.,al. [preprint]Broad protection against Influenza A Viruses via an adjuvant-free mucosal microparticle vaccine with conserved CD8/CD4 bispecific peptides. https://doi.org/10.64898/2026.03.29.715080. Abstract
submitted by kickingbird at Apr, 3, 2026 from https://doi.org/10.64898/2026.03.29.715080 (via https://www.biorxiv.org/content/10.64898/2026.03.29.715080v1)
Influenza A viruses (IAVs) cause substantial global morbidity and mortality and are responsible for most known viral pandemics. Their rapid antigenic evolution enables escape from natural and vaccine-induced ... Liu D, Fan Y, Leung KY, Zhang R, Lam HY, Xie X, Ch. Antiviral activities of multiple antivirals against highly pathogenic avian influenza A H5N1 in vitro and in mice. Emerg Microbes Infect. 2026 Dec;15(1):2645843. Abstract
submitted by kickingbird at Apr, 2, 2026 from Emerg Microbes Infect. 2026 Dec;15(1):2645843 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
In 2024, a bovine H5N1 strain was first isolated from dairy cows in Texas and confirmed to transmit cross-species to humans. Therefore, research on treatments for human infection should be accelerated. ... Alexandra A. Fischer, etc.,al. Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies. Immunity. Abstract
submitted by kickingbird at Mar, 31, 2026 from Immunity (via https://www.sciencedirect.com/science/article/pii/S107476132)
The regular emergence of influenza strains with pandemic potential necessitates vaccines that elicit protective immune responses across genetically diverse human populations. A critical but understudied ... Kim S, Jang EY, Moon SY, Choi EB, Lee HW, Song M-S. Evaluation of Cross-Immunogenicity of Ferret Antisera Following Immunization with H5N1 Vaccine Strains. Vaccines. 2026; 14(4):301. Abstract
submitted by kickingbird at Mar, 31, 2026 from Vaccines. 2026; 14(4):301 (via https://www.mdpi.com/2076-393X/14/4/301)
Background: Highly pathogenic avian influenza H5N1 viruses of clade 2.3.4.4b have spread globally since 2021, causing extensive outbreaks in avian populations and repeated spillovers into diverse mammalian ... Cordero-Ortiz M, Solís-Hernández M, Cayetano-Mondr. Antibody Recognition of Highly and Low-Pathogenic A/H5Nx Influenza Viruses in Sera of Mexican Donors. Pathogens. 2026; 15(4):352. Abstract
submitted by kickingbird at Mar, 31, 2026 from Pathogens. 2026; 15(4):352 (via https://www.mdpi.com/2076-0817/15/4/352)
Influenza A viruses (IAVs) are among the most common sources of new pandemic strains in humans. Spillover from birds to mammals can lead to viral adaptation in new hosts, as seen with IAV H5N1. H5N2 viruses ... Ahmed Mostafa, etc.,al. [preprint]A Live Attenuated Vaccine Candidate against Emerging Highly Pathogenic Cattle-Origin 2.3.4.4b H5N1 Viruses. https://doi.org/10.1101/2025.03.28.646033. Abstract
submitted by kickingbird at Mar, 30, 2026 from https://doi.org/10.1101/2025.03.28.646033 (via https://www.biorxiv.org/content/10.1101/2025.03.28.646033v2)
Influenza viruses present a significant public health risk, causing substantial illness and death in humans each year. Seasonal flu vaccines must be updated regularly, and their effectiveness often decreases ... Kim K, Hwang HS, Pal SS, Tien Le CT, Grovenstein P. Type I interferon signaling is required for resistance to primary influenza virus infection and vaccine-induced long-term immunity. J Virol 0:e00229-26. Abstract
submitted by kickingbird at Mar, 29, 2026 from J Virol 0:e00229-26 (via https://journals.asm.org/doi/10.1128/jvi.00229-26)
Type I interferons (IFNs) are critical for early antiviral defense, yet their role in shaping vaccine-induced immunity remains incompletely understood. Here, we investigated the impact of type I IFN receptor ... Liu B, Yu H, Yan Z, Zou S, Guo J, Cai S, Hu Y, Yan. Identification of thermostability-enhancing mutations in H9N2 avian influenza virus hemagglutinin. J Virol 0:e00168-26. Abstract
submitted by kickingbird at Mar, 29, 2026 from J Virol 0:e00168-26 (via https://journals.asm.org/doi/10.1128/jvi.00168-26)
H9N2 avian influenza viruses (AIVs) remain a significant economic burden on poultry production and a persistent zoonotic threat. Hemagglutinin (HA), a surface glycoprotein mediating viral entry and pathogenesis, ... Yongdong Li, Lei Xie, Suli Jiao, Hongxia Ni, Rui L. Post-Pandemic Emergence H1N1 Strains With Antiviral Resistance–Associated Substitutions and H1/H3 Reassortment in Pediatric Cases: Genomic and Epidemiological Insights From Ningbo, China (2020–2024). Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at Mar, 27, 2026 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/7683935)
Influenza A (H1N1) remains a persistent threat to global public health due to its high mutation rate and immune evasion capacity. This study investigates the epidemiological trends in pediatrics, genetic ... Alina Tscherne, Florian Krammer. Seven decades after the Asian influenza pandemic: A historical review about immunity and vaccines against H2N2. Vaccine. Abstract
submitted by kickingbird at Mar, 27, 2026 from Vaccine (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
In 1957, a reassortant influenza A virus (IAV) H2N2 subtype emerged in humans and encountered a population that was antigenically na?ve to this subtype. The lack of pre-existing immunity to the H2 hemagglutinin ... Krupinsky KC, Bendall EE, Zhu Y, Stockwell MS, Ngu. The impact of viral and host factors on the influenza A virus transmission bottleneck. PLoS Pathog. 2026 Mar 25;22(3):e1014079. Abstract
submitted by kickingbird at Mar, 26, 2026 from PLoS Pathog. 2026 Mar 25;22(3):e1014079 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Transmission bottlenecks are defined by the number of unique virions or genotypes that establish an infection, and they restrict viral diversity that passes from one infected host to another. Previous ... Tiphaine Cayol, Sonia Villanueva-Hernández, Emily. Porcine influenza mAbs to H3, H5, and H7 hemagglutinins recognize H3 egg adapted site and target the HA stem. Discovery Immunology, Volume 5, Issue 1, 2026, kya. Abstract
submitted by kickingbird at Mar, 25, 2026 from Discovery Immunology, Volume 5, Issue 1, 2026, kya (via https://academic.oup.com/discovimmunology/article/5/1/kyag00)
Introduction: Monoclonal antibodies (mAbs) are critical tools for elucidating viral evolution, informing vaccine design, and developing antiviral therapeutics. Large-animal models, such as the pig, that ... 7184 items, 20/Page, Page[23/360][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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