Moheimani F, etc.,al. Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics. Respir Res. 2018 Aug 2;19(1):145.. Abstract
submitted by kickingbird at Aug, 5, 2018 from Respir Res. 2018 Aug 2;19(1):145. (via https://www.ncbi.nlm.nih.gov/pubmed/30068332)
BACKGROUND: Specific microRNAs (miRNAs) play essential roles in airway remodeling in asthma. Infection with influenza A virus (IAV) may also magnify pre-existing airway remodeling leading to asthma exacerbation. ... Kim YJ, etc.,al. Complement C3 Plays a Key Role in Inducing Humoral and Cellular Immune Responses to Influenza Virus Strain Specific HA or Cross Protective M2e vaccination. J Virol. 2018 Aug 1. pii: JVI.00969-18.. Abstract
submitted by kickingbird at Aug, 5, 2018 from J Virol. 2018 Aug 1. pii: JVI.00969-18. (via https://www.ncbi.nlm.nih.gov/pubmed/30068650)
The complement pathway is involved in eliminating antigen immune complexes. However, the role of the C3 complement system remains largely unknown in influenza virus M2 extracellular (M2e) domain or hemagglutinin ... Mehta K, Goneau LW, Wong J, L´Huillier AG. Zoonotic Influenza and Human Health-Part 2: Clinical Features, Diagnosis, Treatment, and Prevention Strategies. Curr Infect Dis Rep. 2018 Aug 1;20(10):38. Abstract
submitted by kickingbird at Aug, 5, 2018 from Curr Infect Dis Rep. 2018 Aug 1;20(10):38 (via https://www.ncbi.nlm.nih.gov/pubmed/30069787)
PURPOSE OF REVIEW: Zoonotic influenza viruses are those influenza viruses that cross the animal-human barrier and can cause disease in humans, manifesting from minor respiratory illnesses to multiorgan ... Goneau LW, Mehta K, Wong J, L´Huillier AG. Zoonotic Influenza and Human Health-Part 1: Virology and Epidemiology of Zoonotic Influenzas. Curr Infect Dis Rep. 2018 Aug 1;20(10):37.. Abstract
submitted by kickingbird at Aug, 5, 2018 from Curr Infect Dis Rep. 2018 Aug 1;20(10):37. (via https://ww.ncbi.nlm.nih.gov/pubmed/30069735)
PURPOSE OF REVIEW: Zoonotic influenza viruses are those that cross the animal-human barrier and can cause disease in humans, manifesting from minor respiratory illnesses to multiorgan dysfunction. They ... Lin YJ, Shih YJ, Chen CH, Fang CT. Aluminum salts as an adjuvant for pre-pandemic influenza vaccines: a meta-analysis. Sci Rep. 2018 Jul 30;8(1):11460.. Abstract
submitted by kickingbird at Aug, 5, 2018 from Sci Rep. 2018 Jul 30;8(1):11460. (via https://www.ncbi.nlm.nih.gov/pubmed/30061656)
Avian-origin H5/H7 influenza has the potential to cause the next influenza pandemic. Availability of effective vaccines is an essential part of pre-pandemic preparedness. However, avian influenza surface ... Elliott S, Keaton AA, Chu JD, Reed CC, Garman. A Synthetic Micro-Consensus DNA Vaccine Generates Comprehensive Influenza-A H3N2 Immunity and Protects Mice Against Lethal Challenge by Multiple H3N2 Viruses. Hum Gene Ther. 2018 Jul 31. Abstract
submitted by kickingbird at Aug, 5, 2018 from Hum Gene Ther. 2018 Jul 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30062926)
Influenza-A H3N2 viruses circulate globally, leading to substantial morbidity and mortality. Commercially-available, antigen-matched influenza vaccines must be updated frequently to match dynamic sequence ... Wang J, Liu M, Ding N, Li Y, Shao J, Zhu M. Vaccine based on antibody-dependent cell-mediated cytotoxicity epitope on the H1N1 influenza virus increases mortality in vaccinated mice. Biochem Biophys Res Commun. 2018 Jul 28.. Abstract
submitted by kickingbird at Aug, 5, 2018 from Biochem Biophys Res Commun. 2018 Jul 28. (via https://www.ncbi.nlm.nih.gov/pubmed/30064910)
Antibody-dependent cell-mediated cytotoxicity bridges humoral immunity and cellular immunity. Thus vaccine candidates which can elicit both broadly neutralizing antibodies and potent antibody-dependent ... Deng L, Chang TZ, Wang Y, Li S, Wang S, Matsu. Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice. PNAS 2018 Jul 31. pii: 201805713. Abstract
submitted by kickingbird at Aug, 5, 2018 from PNAS 2018 Jul 31. pii: 201805713 (via https://www.ncbi.nlm.nih.gov/pubmed/30065113)
Influenza is a persistent threat to public health. Here we report that double-layered peptide nanoparticles induced robust specific immunity and protected mice against heterosubtypic influenza A virus ... Westenius V, M?kel? SM, Julkunen I, ?sterlund P. Highly Pathogenic H5N1 Influenza A Virus Spreads Efficiently in Human Primary Monocyte-Derived Macrophages and Dendritic Cells. Front Immunol. 2018 Jul 17;9:1664. Abstract
submitted by kickingbird at Aug, 5, 2018 from Front Immunol. 2018 Jul 17;9:1664 (via https://www.ncbi.nlm.nih.gov/pubmed/30065728)
Influenza A viruses cause recurrent epidemics and occasional global pandemics. Wild birds are the natural reservoir of influenza A virus from where the virus can be transmitted to poultry or to mammals ... Jang Y, Jin M, Seo SH. Histamine contributes to severe pneumonia in pigs infected with 2009 pandemic H1N1 influenza virus. Arch Virol. 2018 Jul 31.. Abstract
submitted by kickingbird at Aug, 5, 2018 from Arch Virol. 2018 Jul 31. (via https://www.ncbi.nlm.nih.gov/pubmed/30066270)
Histamine is a biogenic amine that influences many immune cells. In this study, we investigated the effect of histamine on the pathogenesis of 2009 pandemic H1N1 influenza virus in pigs. Histamine was ... Al Khatib HA, Al Thani AA, Yassine HM. Evolution and dynamics of the pandemic H1N1 influenza hemagglutinin protein from 2009 to 2017. Arch Virol. 2018 Jul 31. doi: 10.1007/s00705-018-3. Abstract
submitted by kickingbird at Aug, 5, 2018 from Arch Virol. 2018 Jul 31. doi: 10.1007/s00705-018-3 (via https://www.ncbi.nlm.nih.gov/pubmed/30066273)
The emergence of swine-origin pandemic H1N1 (pH1N1) in 2009 invigorated extensive surveillance programs worldwide which have resulted in the deposition of large numbers of H1N1 sequences to Genbank. In ... Kaitlyn Vette, Christina Bareja, Robert Clark & Ap. Establishing thresholds and parameters for pandemic influenza severity assessment, Australia. Bulletin of the World Health Organization Volume 9. Abstract
submitted by kickingbird at Aug, 2, 2018 from Bulletin of the World Health Organization Volume 9 (via http://www.who.int/bulletin/volumes/96/8/18-211508-ab/en/)
Objective
To implement the World Health Organization’s pandemic influenza severity assessment tool in Australia, using multiple sources of data to establish thresholds and measure influenza severity indicators.
Methods
We ... Tachibana M, etc.,al. Clasmatodendrosis is associated with dendritic spines and does not represent autophagic astrocyte death in influenza-associated encephalopathy. Brain Dev. 2018 Jul 26. pii: S0387-7604(18)30099-8. Abstract
submitted by kickingbird at Aug, 2, 2018 from Brain Dev. 2018 Jul 26. pii: S0387-7604(18)30099-8 (via https://www.ncbi.nlm.nih.gov/pubmed/30057207)
BACKGROUND: Influenza-associated encephalopathy (IAE) is one of the most serious CNS complications of an influenza virus infection, with unclear pathophysiology. Clasmatodendrosis is a complex of morphological ... Tapia R, García V, Mena J, Bucarey S, Medina. Infection of novel reassortant H1N2 and H3N2 swine influenza A viruses in the guinea pig model. Vet Res. 2018 Jul 27;49(1):73.. Abstract
submitted by kickingbird at Aug, 2, 2018 from Vet Res. 2018 Jul 27;49(1):73. (via https://www.ncbi.nlm.nih.gov/pubmed/30053826)
Novel H1N2 and H3N2 swine influenza A viruses (IAVs) were identified in commercial farms in Chile. These viruses contained H1, H3 and N2 sequences, genetically divergent from IAVs described worldwide, ... Diefenbacher M, Sun J, Brooke CB. The parts are greater than the whole: the role of semi-infectious particles in influenza A virus biology. Curr Opin Virol. 2018 Jul 24;33:42-46. Abstract
submitted by kickingbird at Aug, 2, 2018 from Curr Opin Virol. 2018 Jul 24;33:42-46 (via https://www.ncbi.nlm.nih.gov/pubmed/30053722)
The influenza A virus (IAV) genome is incorporated into newly produced virions through a tightly orchestrated process that is one of the best studied examples of genome packaging by a segmented virus. ... Guo Z, Wilson JR, York IA, Stevens J. Biosensor-based epitope mapping of antibodies targeting the hemagglutinin and neuraminidase of influenza A virus. J Immunol Methods. 2018 Jul 24. pii: S0022-1759(17. Abstract
submitted by kickingbird at Aug, 2, 2018 from J Immunol Methods. 2018 Jul 24. pii: S0022-1759(17 (via https://www.ncbi.nlm.nih.gov/pubmed/30053389)
Characterization of the epitopes on antigen recognized by monoclonal antibodies (mAb) is useful for the development of therapeutic antibodies, diagnostic tools, and vaccines. Epitope mapping also provides ... Yogaratnam J, etc.,al. Antiviral Activity, Safety, and Pharmacokinetics of AL-794, a Novel Oral Influenza Endonuclease Inhibitor: Results of an Influenza Human Challenge Study. J Infect Dis. 2018 Jul 26.. Abstract
submitted by kickingbird at Aug, 2, 2018 from J Infect Dis. 2018 Jul 26. (via https://www.ncbi.nlm.nih.gov/pubmed/30053042)
Background: AL-794 is an orally active prodrug of ALS-033719, which selectively inhibits the endonuclease domain of influenza virus A and B polymerase.Methods: In a phase 1, double-blinded, randomized, ... Jasmina M. Luczo, etc.,al. Evolution of high pathogenicity of H5 avian influenza virus: haemagglutinin cleavage site selection of reverse-genetics mutants during passage in chickens. Scientific Reports volume 8, Article number: 1151. Abstract
submitted by kickingbird at Aug, 2, 2018 from Scientific Reports volume 8, Article number: 1151 (via https://www.nature.com/articles/s41598-018-29944-z)
Low pathogenicity avian influenza viruses (LPAIVs) are generally asymptomatic in their natural avian hosts. LPAIVs can evolve into highly pathogenic forms, which can affect avian and human populations ... Kumar A, etc.,al. MicroRNA hsa-miR-324-5p Suppresses H5N1 Virus Replication by Targeting the Viral PB1 and Host CUEDC2. J Virol. 2018 Jul 25. Abstract
submitted by kickingbird at Jul, 29, 2018 from J Virol. 2018 Jul 25 (via https://www.ncbi.nlm.nih.gov/pubmed/30045983)
MicroRNAs (miRNAs) are small non-coding RNAs that are crucial post-transcriptional regulator for host mRNAs. Recent studies indicate that miRNAs may modulate host response during RNA viruses infection. ... Nachbagauer R, Krammer F, Albrecht RA. A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study. Vaccines (Basel). 2018 Jul 25;6(3).. Abstract
submitted by kickingbird at Jul, 29, 2018 from Vaccines (Basel). 2018 Jul 25;6(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30044403)
Influenza viruses cause severe diseases and mortality in humans on an annual basis. The current influenza virus vaccines can confer protection when they are well-matched with the circulating strains. However, ... 6898 items, 20/Page, Page[222/345][|<<] [|<] [221] [222] [223] [224] [225] [226] [227] [228] [229] [230] [>|] [>>|] |
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