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2026-10-9 17:38:43
Article

Mark A Power, etc.,al. Characterisation of immune responses targeting highly pathogenic avian influenza A(H5) viruses in health-care workers in the Netherlands: an observational, cross-sectional analysis. The Lancet Microbe.  Abstract  
submitted by kickingbird at Apr, 16, 2026 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
BackgroundHighly pathogenic avian influenza A(H5) viruses pose a pandemic threat, with a history of mammalian adaptation and zoonotic spillovers into humans. We aimed to determine whether pre-existing ...

Wei Zhang, etc.,al. Molecular Characterization and Pathogenicity of H9N2 Avian Influenza Viruses in Poultry in Shandong Province, China, 2021–2023. Poultry Science.  Abstract  
submitted by kickingbird at Apr, 16, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 avian influenza virus (AIV) is currently widespread worldwide, posing a severe threat to the poultry industry and public health. To investigate the epidemiological characteristics, genomic evolution, ...

Budt M, Barac I, Kohs J, Krischuns T, Naffakh N, W. Historical Pandemic and Contemporary Influenza A Viruses Reveal PB2 M631L as a Convergent Adaptation to Human ANP32. Microorganisms. 2026; 14(4):859.  Abstract  
submitted by kickingbird at Apr, 16, 2026 from Microorganisms. 2026; 14(4):859 (via https://www.mdpi.com/2076-2607/14/4/859)
Understanding the genetic changes that allow avian influenza A viruses (IAVs) to switch their natural hosts and establish productive infection in humans is important for pandemic risk assessment. Adaptations ...

Branda F, Petrosillo N, Ceccarelli G, Scarpa F, Gi. Influenza A(H3N2) Subclade K (J.2.4.1): Molecular Characterization, Antigenic Divergence, and Global Spread During the 2025/26 Season. Infectious Disease Reports. 2026; 18(2):37.  Abstract  
submitted by kickingbird at Apr, 16, 2026 from Infectious Disease Reports. 2026; 18(2):37 (via https://www.mdpi.com/2036-7449/18/2/37)
Background: Influenza A(H3N2) continues to evolve rapidly, frequently eroding population immunity and challenging seasonal vaccine strain selection. During the 2025/26 season, the A(H3N2) subclade K (J.2.4.1) ...

Ojha CR, Rovito SW, Banoth B, Kim H, Jones JC, Ala. Effect of Acid-Stabilizing Hemagglutinin Mutations on Immunogenicity and Heterologous Protection by H1N1 Influenza Virus mRNA-LNP Vaccines. Viruses. 2026; 18(4):467.  Abstract  
submitted by kickingbird at Apr, 16, 2026 from Viruses. 2026; 18(4):467 (via https://www.mdpi.com/1999-4915/18/4/467)
While current influenza vaccines often lack broad protection against antigenically drifted strains, some modified hemagglutinin (HA) protein antigens have shown promise in eliciting broadly neutralizing ...

Samuel A. Turner, David J. Pattinson, etc.,al. [preprint]Predicting the antigenic evolution of seasonal influenza viruses using phylogenetic convergence. https://doi.org/10.64898/2026.04.10.717627.  Abstract  
submitted by kickingbird at Apr, 15, 2026 from https://doi.org/10.64898/2026.04.10.717627 (via https://www.biorxiv.org/content/10.64898/2026.04.10.717627v1)
The antigenic evolution of human seasonal influenza viruses is primarily driven by single amino acid substitutions immediately adjacent to the receptor binding site in the hemagglutinin (HA) protein. The ...

Ibrahim M, Mostafa D, Manie EA, El-Sanousi AA, Sha. Field study using sentinel birds and ELISA for differentiating infected from vaccinated animals (DIVA) in chicken flocks vaccinated with inactivated avian influenza H5 vaccines. Br Poult Sci. 2026 Apr 13:1-8.  Abstract  
submitted by kickingbird at Apr, 15, 2026 from Br Poult Sci. 2026 Apr 13:1-8 (via https://www.tandfonline.com/doi/full/10.1080/00071668.2026.2)
1. This study used unvaccinated sentinels plus Avian Influenza Virus (AIV) specific ELISA for differentiating infected from vaccinated animals (DIVA). Birds assessed were from 10 broiler flocks (F1-F10), ...

Li B, Wu Y, Song Y, Guo H, Qin G, Lin L, Zhao H, R. Genetic Characterization and Pathogenicity of a Triple-Reassortant H1N1 Swine Influenza Virus Isolated in Guangdong. Transbound Emerg Dis. 2026 Apr 10;2026:7175378.  Abstract  
submitted by kickingbird at Apr, 15, 2026 from Transbound Emerg Dis. 2026 Apr 10;2026:7175378 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/7175378)
An H1N1 subtype swine influenza virus (SIV) was isolated from nasal swabs collected from pigs with suspected swine influenza (SI) on a farm in Guangdong, China. The virus, designated A/Swine/Guangdong/JJK/2025(H1N1) ...

Liu Y, Wu S, Liu Y, Chen J, Xiao J, Zhang J, Huang. Molecular and antigenic characteristics of the influenza B virus in Guangzhou, 2022-2023. Virol J. 2026 Apr 14.  Abstract  
submitted by kickingbird at Apr, 15, 2026 from Virol J. 2026 Apr 14 (via https://link.springer.com/article/10.1186/s12985-026-03141-1)
Background: The Influenza B virus (IBV), which accounts for nearly a quarter of annual global influenza-associated morbidity, represents a major human respiratory pathogen. Since late 2019, IBV transmission ...

Swetha Vijayakrishnan, etc.,al. [preprint]Molecular architecture of Influenza A virions. https://doi.org/10.64898/2026.04.02.715802.  Abstract  
submitted by kickingbird at Apr, 11, 2026 from https://doi.org/10.64898/2026.04.02.715802 (via https://www.biorxiv.org/content/10.64898/2026.04.02.715802v1)
Influenza A viruses (IAV) are clinically important pathogens that cause seasonal epidemics and pandemics in humans. IAV produce pleomorphic, enveloped virions, which can range from a spherical or bacilliform ...

Lin, X., Guan, W., Chen, L. et al. Birth imprinting effects on the antibody responses of H7N9 patients from 2013-2018 in China. Commun Med (2026).  Abstract  
submitted by kickingbird at Apr, 9, 2026 from Commun Med (2026) (via https://www.nature.com/articles/s43856-026-01554-1)
BackgroundThere is an urgent need to understand the immune correlates of protection against avian influenza viruses (AIV), where pre-existing immunity may be limited.MethodsHere, we characterized the antibody ...

Ogrzewalska, M., Vanstreels, R.E.T., Pereira, E.C.. Genomic analysis of high pathogenicity avian influenza viruses from Antarctica reveals multiple introductions from South America. Nat Commun (2026).  Abstract  
submitted by kickingbird at Apr, 8, 2026 from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-71544-3)
The spread of high pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b into Antarctica poses a major threat to polar wildlife. We report the detection of H5N1 in carcasses of eight species during ...

Liang J, Zeng Z, Liao K, Liao M, Fang Z, Kong L, F. Dynamic feature selection improves influenza forecasting accuracy and generalization across countries. J Adv Res. 2026 Apr 4:S2090-1232(26)00288-2.  Abstract  
submitted by kickingbird at Apr, 8, 2026 from J Adv Res. 2026 Apr 4:S2090-1232(26)00288-2 (via https://www.sciencedirect.com/science/article/pii/S209012322)
Introduction: The differentiation in epidemic patterns and multiple influencing factors pose significant challenges to influenza forecasting, highlighting the need for novel methods to improve predictive ...

Stallknecht DE, Carter DL, Sullivan-Brügger L, Cao. Seasonal Infection and Antibody Response to Highly Pathogenic H5N1 Influenza A Virus in Ducks in the Mississippi and Central Flyways, United States. Can J Microbiol. 2026 Apr 6.  Abstract  
submitted by kickingbird at Apr, 8, 2026 from Can J Microbiol. 2026 Apr 6 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0274)
Clade 2.3.4.4b A/goose/Guangdong/1/1996 (Gs/GD) H5N1 highly pathogenic (HP) influenza A virus (IAV) (HP H5N1) infection in Blue-winged Teal in the Mississippi Flyway in the United States during the 2022/2023 ...

Kwon T, Gu W, Morozov I, Carossino M, Lyoo EL, McD. Pigs lacking Natural Killer T cells have altered cellular responses to influenza. PLoS Pathog 22(4): e1014094.  Abstract  
submitted by kickingbird at Apr, 8, 2026 from PLoS Pathog 22(4): e1014094 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
It is increasingly recognized that innate T cells such as natural killer T (NKT) cells, mucosal associated invariant T (MAIT) cells, and γδ T cells play an important role in shaping adaptive immune responses ...

Sarkar, S., Zhou, Y., Yang, Y., & Qiu, P. Online monitoring and early detection of influenza outbreaks using exponentially weighted spatial lasso: a case study in China during 2014-2020. Journal of Applied Statistics, 53(5), 914–936.  Abstract  
submitted by kickingbird at Apr, 8, 2026 from Journal of Applied Statistics, 53(5), 914–936 (via https://www.tandfonline.com/doi/full/10.1080/02664763.2025.2)
Influenza poses a persistent public health threat in China, with substantial impacts on health and the economy, especially during seasonal epidemics and emerging outbreaks. Seasonality, local clustering, ...

Yike Teresa Shi, Michael A Martin, Daniel B Weissm. Genetic drift acts strongly on influenza virus populations within acute human infections but is obscured by other factors within acutely infected swine. Virus Evolution, 2026.  Abstract  
submitted by kickingbird at Apr, 6, 2026 from Virus Evolution, 2026 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The evolutionary dynamics of seasonal influenza A viruses (IAVs) have been well characterized at the population level, with antigenic drift known to be a major force in driving strain turnover. The evolution ...

Jack A. Hassard, etc.,al. [preprint]Bovine H5N1 influenza viruses have adapted to more efficiently use receptors abundant in cattle. https://doi.org/10.64898/2026.04.02.715584.  Abstract  
submitted by kickingbird at Apr, 6, 2026 from https://doi.org/10.64898/2026.04.02.715584 (via https://www.biorxiv.org/content/10.64898/2026.04.02.715584v1)
Sustained mammal-to-mammal transmission of high pathogenicity H5N1avian influenza viruses is reshaping the host range of these pathogens. One of the longest-running mammalian transmission chains involves ...

Mariana Baz, etc.,al. [preprint]Baloxavir and molnupiravir protect against severe A/H5N1 infection in immunosuppressed hamsters. https://doi.org/10.21203/rs.3.rs-9193430/v1.  Abstract  
submitted by kickingbird at Apr, 6, 2026 from https://doi.org/10.21203/rs.3.rs-9193430/v1 (via https://www.researchsquare.com/article/rs-9193430/v1)
Highly pathogenic avian influenza A/H5N1 viruses continue to spread among multiple mammalian species, including humans, raising concerns about zoonotic transmission and pandemic preparedness. Immunocompromised ...

Xinlan zhang, etc.,al. Genetic and Biological Characterization of a Duck-Origin Clade 2.3.4.4b H5N6 Avian Influenza Virus Reveals Partial Mammalian Adaptation. Veterinary Microbiology.  Abstract  
submitted by kickingbird at Apr, 6, 2026 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Clade 2.3.4.4b H5Nx highly pathogenic avian influenza viruses (HPAIVs) have caused extensive outbreaks in poultry worldwide. H5 HPAIVs have caused sporadic but severe human infections in China, representing ...

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