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Ismail ZM, El-Deeb AH, El-Safty MM, Hussein HA. Enhanced pathogenicity of low-pathogenic H9N2 avian influenza virus after vaccination with infectious bronchitis live attenuated vaccine. Vet World. 2018 Jul;11(7):977-985.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Vet World. 2018 Jul;11(7):977-985 (via https://www.ncbi.nlm.nih.gov/pubmed/30147269)
Aim: In the present study, two experiments were carried out for studying the pathogenicity of H9N2 avian influenza virus (AIV) in broiler chickens after vaccination with different live respiratory viral ...

Veerapandian R, Snyder JD, Samarasinghe AE. Influenza in Asthmatics: For Better or for Worse?. Front Immunol. 2018 Aug 10;9:1843.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 10;9:1843 (via https://www.ncbi.nlm.nih.gov/pubmed/30147697)
Asthma and influenza are two pathologic conditions of the respiratory tract that affect millions worldwide. Influenza virus of the 2009 pandemic was highly transmissible and caused severe respiratory disease ...

Zheng D, Gao F, Zhao C, Ding Y, Cao Y. Comparative effectiveness of H7N9 vaccines in healthy individuals. Hum Vaccin Immunother. 2018 Aug 27..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Hum Vaccin Immunother. 2018 Aug 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30148691)
BACKGROUND: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 ...

Benkaroun J, Robertson GJ, Whitney H, Lang AS. Analysis of the Variability in the Non-Coding Regions of Influenza A Viruses. Vet Sci. 2018 Aug 25;5(3)..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Vet Sci. 2018 Aug 25;5(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30149635)
The genomes of influenza A viruses (IAVs) comprise eight negative-sense single-stranded RNA segments. In addition to the protein-coding region, each segment possesses 5' and 3' non-coding regions (NCR) ...

Ni Y, Guo J, Turner D, Tizard I. An Improved Inactivated Influenza Vaccine with Enhanced Cross Protection. Front Immunol. 2018 Aug 9;9:1815..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 9;9:1815. (via https://www.ncbi.nlm.nih.gov/pubmed/30140267)
Current inactivated influenza vaccines are strain-specific and poorly effective against variant or mismatched viruses. They are standardized based on their hemagglutinin (HA) or ability to induce strain-specific ...

Li R, Zhang T, Bai Y, Li H, Wang Y, Bi Y, Chang J. Live Poultry Trading Drives China´s H7N9 Viral Evolution and Geographical Network Propagation. Front Public Health. 2018 Jul 27;6:210.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Public Health. 2018 Jul 27;6:210 (via https://www.ncbi.nlm.nih.gov/pubmed/30140667)
The on-going reassortment, human-adapted mutations, and spillover events of novel A(H7N9) avian influenza viruses pose a significant challenge to public health in China and globally. However, our understanding ...

Saavedra-Monta?ez M, etc.,al. Identification and genomic characterization of influenza viruses with different origin in Mexican pigs. Transbound Emerg Dis. 2018 Aug 20.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Transbound Emerg Dis. 2018 Aug 20 (via https://www.ncbi.nlm.nih.gov/pubmed/30126057)
Swine influenza is a worldwide disease, which causes damage to the respiratory system of pigs. The H1N1 and H3N2 subtypes circulate mainly in the swine population of Mexico. There is evidence that new ...

Wang J, etc.,al. A study on mother-to-fetus/infant transmission of influenza A(H7N9) virus: two case reports and a review of literature. Clin Respir J. 2018 Aug 20.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Clin Respir J. 2018 Aug 20 (via https://www.ncbi.nlm.nih.gov/pubmed/30126042)
OBJECTIVES: The prevention strategies for mother-to-fetus/infant transmission of H7N9 virus have not been well understood, and the study on this subject will provide further insights.METHODS: Reverse transcriptase ...

Xia C, Seo YJ, Studstill CJ, Vijayan M, Wolf J. Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice. Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)302.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)302 (via https://www.ncbi.nlm.nih.gov/pubmed/30125617)
Influenza continues to pose a threat to public health by causing illness and mortality in humans. Discovering host factors that regulate influenza virus propagation is vital for the development of novel ...

Sood R, etc.,al. Neuraminidase inhibitors susceptibility profiles of highly pathogenic influenza A (H5N1) viruses isolated from avian species in India (2006-2015).. Antiviral Res. 2018 Aug 17..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Antiviral Res. 2018 Aug 17. (via https://www.ncbi.nlm.nih.gov/pubmed/30125616)
We tested 65 highly pathogenic avian influenza (HPAI) A(H5N1) viruses, isolated from avian species in India between 2006 and 2015, for susceptibility to the FDA approved neuraminidase (NA) inhibitors (NAIs), ...

Kucharski AJ, Lessler J, Cummings DAT, Riley S. Timescales of influenza A/H3N2 antibody dynamics. PLoS Biol. 2018 Aug 20;16(8):e2004974..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from PLoS Biol. 2018 Aug 20;16(8):e2004974. (via https://www.ncbi.nlm.nih.gov/pubmed/30125272)
Human immunity influences the evolution and impact of influenza strains. Because individuals are infected with multiple influenza strains during their lifetime, and each virus can generate a cross-reactive ...

Bi Y, etc.,al. Clinical and immunological characteristics of human infections with H5N6 avian influenza virus. Clin Infect Dis. 2018 Aug 16.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Clin Infect Dis. 2018 Aug 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30124826)
Background: H5N6 avian influenza virus (AIV) has caused sporadic, recurring outbreaks in China and Southeast Asia since 2013, with 19 human infections and 13 deaths. Seventeen of these infections occurred ...

Shearn-Bochsler VI, Knowles S, Ip H. Lethal Infection of Wild Raptors with Highly Pathogenic Avian Influenza H5N8 and H5N2 Viruses in the United States, 2014-15. J Wildl Dis. 2018 Aug 20..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from J Wildl Dis. 2018 Aug 20. (via https://www.ncbi.nlm.nih.gov/pubmed/30124391)
An outbreak of highly pathogenic avian influenza (HPAI) led to heavy losses of poultry in commercial farms in North America in 2014-15. Enhanced surveillance by virologists and pathologists at the US Geological ...

Eriksson P, etc.,al. Characterization of avian influenza virus attachment patterns to human and pig tissues. Sci Rep. 2018 Aug 15;8(1):12215..  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Sci Rep. 2018 Aug 15;8(1):12215. (via https://www.ncbi.nlm.nih.gov/pubmed/30111851)
Wild birds of Anseriformes and Charadriiformes are natural reservoirs of influenza A viruses (IAVs). Occasionally, IAVs transmit and adapt to mammalian hosts, and are maintained as epidemic strains in ...

Hancock AS, etc.,al. Transcriptome analysis of infected and bystander type 2 alveolar epithelial cells during influenza A virus infection reveals in vivo Wnt pathway downregulation. J Virol. 2018 Aug 15. pii: JVI.01325-18.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from J Virol. 2018 Aug 15. pii: JVI.01325-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30111569)
Influenza virus outbreaks remain a serious threat to public health. Greater understanding of how cells targeted by the virus respond to the infection can provide insight into the pathogenesis of disease. ...

Celestino I, etc.,al. Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice. Front Immunol. 2018 Jul 30;9:1747.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1747 (via https://www.ncbi.nlm.nih.gov/pubmed/30105026)
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple ...

Li X, Li C, Liu JC, Pan YP, Li YG. In vitro effect of Porphyromonas gingivalis combined with influenza A virus on respiratory epithelial cells. Arch Oral Biol. 2018 Apr 5;95:125-133.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Arch Oral Biol. 2018 Apr 5;95:125-133 (via https://www.ncbi.nlm.nih.gov/pubmed/30107300)
OBJECTIVE: Respiratory epithelial cells are the first natural barrier against bacteria and viruses; hence, the interactions among epithelial cells, bacteria, and viruses are associated with disease occurrence ...

Al-Ahdal MN, etc.,al. Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D. Front Immunol. 2018 Jul 30;9:1586.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1586 (via https://www.ncbi.nlm.nih.gov/pubmed/30105014)
Surfactant protein D (SP-D) is expressed in the mucosal secretion of the lung and contributes to the innate host defense against a variety of pathogens, including influenza A virus (IAV). SP-D can inhibit ...

Lee JM, etc.,al. Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants. Proc Natl Acad Sci U S A. 2018 Aug 13.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from Proc Natl Acad Sci U S A. 2018 Aug 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30104379)
Human influenza virus rapidly accumulates mutations in its major surface protein hemagglutinin (HA). The evolutionary success of influenza virus lineages depends on how these mutations affect HA's functionality ...

Wu Y, etc.,al. Prenatal influenza vaccination rescues impairments of social behavior and lamination in a mouse model of autism. J Neuroinflammation. 2018 Aug 13;15(1):228.  Abstract  
submitted by kickingbird at Aug, 20, 2018 from J Neuroinflammation. 2018 Aug 13;15(1):228 (via https://www.ncbi.nlm.nih.gov/pubmed/30103815)
BACKGROUND: Prenatal infection is a substantial risk factor for neurodevelopmental disorders such as autism in offspring. We have previously reported that influenza vaccination (VAC) during early pregnancy ...

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