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2024-3-29 18:24:16
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Cong YL, Wang CF, Yan CM, Peng JS, Jiang ZL, Liu J. Swine infection with H9N2 influenza viruses in China in 2004. Virus Genes. 2008 Apr 10.  Abstract  
submitted by kickingbird at Apr, 13, 2008 from Virus Genes. 2008 Apr 10 (via http://www.ncbi.nlm.nih.gov/pubmed/18401696?ordinalpos=9&ito)
In 2004, H9N2 influenza A viruses were isolated from pigs with respiratory syndrome in commercial swine farms in Henan province, China. Antigenic and genetic characterization were performed for seven swine ...

Yu H, Hua RH, Wei TC, Zhou YJ, Tian ZJ, Li GX, Liu. Isolation and genetic characterization of avian origin H9N2 influenza viruses from pigs in China. Vet Microbiol. 2008 Mar 6.  Abstract  
submitted by kickingbird at Apr, 13, 2008 from Vet Microbiol. 2008 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/18403137?ordinalpos=5&ito)
As pigs are susceptible to infection with both avian and human influenza A viruses, they have been proposed to be an intermediate host for the adaptation of avian influenza viruses to humans. In April ...

Shibuya T, Yamashiro T, Masaike Y, Ohuchi M, Uechi. Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constructed human Fab library. Microbiol Immunol. 2008;52(3):162-70.  Abstract  
submitted by kickingbird at Apr, 13, 2008 from Microbiol Immunol. 2008;52(3):162-70 (via http://www.ncbi.nlm.nih.gov/pubmed/18402598?ordinalpos=7&ito)
A combinatorial Fab library was constructed in pComb3H phagemid vectors, using RNA from peripheral blood lymphocytes of a healthy volunteer who had recovered from an influenza A virus infection. The library ...

Usami A, Sasaki T, Satoh N, Akiba T, Yokoshima S,. Oseltamivir Enhances Hippocampal Network Synchronization. J Pharmacol Sci. 2008 Apr 9.  Abstract  
submitted by kickingbird at Apr, 13, 2008 from J Pharmacol Sci. 2008 Apr 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18403897?ordinalpos=3&ito)
Oseltamivir, a widely used anti-influenza drug, inhibits virus neuraminidase. A mammalian homologue of this enzyme is expressed in the brain, yet the effect of oseltamivir on central neurons is largely ...

Ilyushina NA, Govorkova EA, Gray TE, Bovin NV, Web. Human-Like Receptor Specificity Does Not Affect the Neuraminidase-Inhibitor Susceptibility of H5N1 Influenza Viruses. PLoS Pathog. 2008 Apr 11;4(4):e1000043.  Full Text  
submitted by kickingbird at Apr, 13, 2008 from PLoS Pathog. 2008 Apr 11;4(4):e1000043 (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
If highly pathogenic H5N1 influenza viruses acquire affinity for human rather than avian respiratory epithelium, will their susceptibility to neuraminidase (NA) inhibitors (the likely first line of defense ...

Decha P, Rungrotmongkol T, Intharathep P, Malaisre. Source of High Pathogenicity of an Avian Influenza Virus H5N1:Why H5 is Better Cleaved by Furin. Biophys J. 2008 Mar 28.  Abstract  
submitted by kickingbird at Apr, 6, 2008 from Biophys J. 2008 Mar 28 (via http://www.ncbi.nlm.nih.gov/pubmed/18375507?ordinalpos=39&it)
Origin of high pathogenicity of an emerging avian influenza H5N1 due to the -RRRKK- insertion at the cleavage loop of the hemagglutinin H5, was studied using the molecular dynamics technique, in comparison ...

Ono H, Nagano Y, Matsunami N, Sugiyama S, Yamamoto. Oseltamivir, an Anti-influenza Virus Drug, Produces Hypothermia in Mice. Biol Pharm Bull. 2008 Apr;31(4):638-42..  Abstract  
submitted by kickingbird at Apr, 6, 2008 from Biol Pharm Bull. 2008 Apr;31(4):638-42. (via http://www.ncbi.nlm.nih.gov/pubmed/18379055?ordinalpos=32&it)
Oseltamivir phosphate (Tamiflu), an anti-influenza virus drug, is hydrolyzed by carboxylesterase to an active metabolite. The metabolite inhibits the influenza virus-specific neuraminidase. In this study, ...

R?der R, Bruns K, Sharma A, Eissmann A, Hahn F, St. Synthesis of full length PB1-F2 influenza A virus proteins from ´Spanish flu´ and ´bird flu´. J Pept Sci. 2008 Apr 1.  Abstract  
submitted by kickingbird at Apr, 6, 2008 from J Pept Sci. 2008 Apr 1 (via http://www.ncbi.nlm.nih.gov/pubmed/18381743?ordinalpos=24&it)
The proapoptotic influenza A virus PB1-F2 protein contributes to viral pathogenicity and is present in most human and avian isolates. Previous synthetic protocols have been improved to provide a synthetic ...

Stouffer AL, Acharya R, Salom D, Levine AS, Di Cos. Structural basis for the function and inhibition of an influenza virus proton channel. Nature 451, 596-599 (31 January 2008).  Abstract  
submitted by kickingbird at Mar, 25, 2008 from Nature 451, 596-599 (31 January 2008) (via http://www.nature.com/nature/journal/v451/n7178/abs/nature06)
The M2 protein from influenza A virus is a pH-activated proton channel that mediates acidification of the interior of viral particles entrapped in endosomes. M2 is the target of the anti-influenza drugs ...

Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. J Gen Virol. 2008 Apr;89(Pt 4):939-48.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Gen Virol. 2008 Apr;89(Pt 4):939-48 (via http://vir.sgmjournals.org/cgi/content/abstract/89/4/939)
Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) are single-stranded nucleic acid-analogue antisense agents that enter cells readily and can reduce gene expression by steric blocking of ...

Song MS, Oh TK, Moon HJ, Yoo DW, Lee EH, Lee JS, K. Ecology of H3 avian influenza viruses in Korea and assessment of their pathogenic potentials. J Gen Virol. 2008 Apr;89(Pt 4):949-57.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Gen Virol. 2008 Apr;89(Pt 4):949-57 (via http://vir.sgmjournals.org/cgi/content/abstract/89/4/949)
To determine the genetic origins of novel H3 avian influenza viruses of chickens and ducks in Korea, genetic characterization of H3 avian influenza viruses isolated from live poultry markets and migratory ...

Vahlenkamp TW, Harder TC, Giese M, Lin F, Teifke J. Protection of cats against lethal influenza H5N1 challenge infection. J Gen Virol. 2008 Apr;89(Pt 4):968-74..  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Gen Virol. 2008 Apr;89(Pt 4):968-74. (via http://vir.sgmjournals.org/cgi/content/abstract/89/4/968)
Highly pathogenic avian influenza virus (HPAIV) H5N1 of Asian origin continues to circulate in poultry and wild birds, causing considerable concern for veterinary and public health in Asia, Europe and ...

Miotto O, Heiny A, Tan TW, August JT, Brusic V. Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis. BMC Bioinformatics. 2008;9 Suppl 1:S18..  Full Text  
submitted by kickingbird at Mar, 25, 2008 from BMC Bioinformatics. 2008;9 Suppl 1:S18. (via http://www.biomedcentral.com/1471-2105/9/S1/S18)
BACKGROUND: The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight against disease. This paper describes a novel method ...

Singh DT, Trehan R, Schmidt B, Bretschneider T.. Comparative phyloinformatics of virus genes at micro and macro levels in a distributed computing environment. BMC Bioinformatics. 2008;9 Suppl 1:S23.  Full Text  
submitted by kickingbird at Mar, 25, 2008 from BMC Bioinformatics. 2008;9 Suppl 1:S23 (via http://www.biomedcentral.com/1471-2105/9/S1/S23)
BACKGROUND: Preparedness for a possible global pandemic caused by viruses such as the highly pathogenic influenza A subtype H5N1 has become a global priority. In particular, it is critical to monitor the ...

Miotto O, Tan TW, Brusic V. Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses. BMC Bioinformatics. 2008;9 Suppl 1:S7.  Full Text  
submitted by kickingbird at Mar, 25, 2008 from BMC Bioinformatics. 2008;9 Suppl 1:S7 (via http://www.biomedcentral.com/1471-2105/9/S1/S7)
BACKGROUND: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising tens of thousands of sequences. ...

Moghadas SM, Bowman CS, R?st G, Wu J.. Population-wide emergence of antiviral resistance during pandemic influenza. PLoS ONE. 2008 Mar 19;3(3):e1839..  Full Text  
submitted by kickingbird at Mar, 25, 2008 from PLoS ONE. 2008 Mar 19;3(3):e1839. (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
BACKGROUND: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic. While resistant strains may initially ...

Vana G, Westover KM.. Origin of the 1918 Spanish influenza virus: A comparative genomic analysis.. Mol Phylogenet Evol. 2008 Feb 14.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from Mol Phylogenet Evol. 2008 Feb 14 (via http://www.ncbi.nlm.nih.gov/pubmed/18353690?ordinalpos=15&it)
To test the avian-origin hypothesis of the 1918 Spanish influenza virus we surveyed influenza sequences from a broad taxonomic distribution and collected 65 full-length genomes representing avian, human ...

Gyarmati P, Conze T, Zohari S, Leblanc N, Nilsson. Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses using padlock probes. J Clin Microbiol. 2008 Mar 19.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Clin Microbiol. 2008 Mar 19 (via http://jcm.asm.org/cgi/content/abstract/JCM.02292-07v1)
A subtyping assay for both the hemagglutinin (HA) and neuraminidase (NA) surface antigens of the Avian Influenza virus (AIV) has been developed. The method uses padlock probe chemistry combined with a ...

Boni MF, Zhou Y, Taubenberger JK, Holmes EC.. Homologous Recombination is Very Rare or Absent in Human Influenza A Virus. J Virol. 2008 Mar 19.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Virol. 2008 Mar 19 (via http://jvi.asm.org/cgi/content/abstract/JVI.02683-07v1)
To determine the extent of homologous recombination in human influenza A virus we assembled a data set of 13,852 sequences representing all eight segments and of both major circulating subtypes, H3N2 and ...

Hao X, Kim TS, Braciale TJ.. Differential response of respiratory dendritic cell subsets to influenza virus infection. J Virol. 2008 Mar 19.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Virol. 2008 Mar 19 (via http://jvi.asm.org/cgi/content/abstract/JVI.02367-07v1)
Dendritic cells (DC) are believed to play an important role in the initiation of innate and adaptive immune responses to infection - including respiratory tract infections where respiratory dendritic cells ...

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