Das P, Li J, Royyuru AK, Zhou R.. Free energy simulations reveal a double mutant avian H5N1 virus hemagglutinin with altered receptor binding specificity. J Comput Chem. 2009 Aug;30(11):1654-63. Abstract
submitted by kickingbird at Oct, 19, 2009 from J Comput Chem. 2009 Aug;30(11):1654-63 (via http://www.ncbi.nlm.nih.gov/pubmed/19399777?ordinalpos=1&ito)
Historically, influenza pandemics have been triggered when an avian influenza virus or a human/avian reassorted virus acquires the ability to replicate efficiently and become transmissible in the human ... The Australia and New Zealand Extracorporeal Membr. Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome. JAMA. 2009 Oct 12. Abstract
submitted by kickingbird at Oct, 19, 2009 from JAMA. 2009 Oct 12 (via http://www.ncbi.nlm.nih.gov/pubmed/19822628)
CONTEXT: The novel influenza A(H1N1) pandemic affected Australia and New Zealand during the 2009 southern hemisphere winter. It caused an epidemic of critical illness and some patients developed severe ... Steel J, Staeheli P, Mubareka S, García-Sastre A,. Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment. J Virol. 2009 Oct 14. Abstract
submitted by kickingbird at Oct, 19, 2009 from J Virol. 2009 Oct 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19828604)
Novel, swine origin influenza viruses of the H1N1 subtype were first detected in humans in April 2009. As of Aug 12th, 180,000 cases had been reported globally. Despite the fact that they are of the same ... McAuley JL, Zhang K, McCullers JA.. The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis. J Virol. 2009 Oct 14.. Abstract
submitted by kickingbird at Oct, 19, 2009 from J Virol. 2009 Oct 14. (via http://www.ncbi.nlm.nih.gov/pubmed/19828614)
The influenza A virus PB1-F2 protein has been implicated as a virulence factor, but the mechanism by which it enhances pathogenicity is not understood. The PB1 gene segment of the H1N1 swine-origin influenza ... Chen SC, Liao CM.. Probabilistic indoor transmission modeling for influenza (sub)type viruses in Taiwan. J Infect. 2009 Oct 6. Abstract
submitted by kickingbird at Oct, 19, 2009 from J Infect. 2009 Oct 6 (via http://www.ncbi.nlm.nih.gov/pubmed/19818365)
OBJECTIVES: To use a probability based transmission modeling approach to examine the influenza risk of infection virus in indoor environments. This was based on 10 years of data gathered from influenza-like ... the 2009 Pandemic Influenza A (H1N1) Virus Hospita. Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009. NEJM. Abstract
submitted by kickingbird at Oct, 15, 2009 from NEJM (via http://content.nejm.org/cgi/content/full/NEJMoa0906695)
Background During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics of the patients who were hospitalized with 2009 H1N1 influenza ... Seema Jain. Underlying conditions linked to more severe cases of influenza A (H1N1). The New England Journal of Medicine. Abstract
submitted by kickingbird at Oct, 13, 2009 from The New England Journal of Medicine (via http://infectiousdiseasenews.com/article/44444.aspx#)
The 2009 H1N1 influenza caused severe illness requiring hospitalization during the outbreak’s peak in the Northern Hemisphere last spring and was a burden on ICUs in the Southern Hemisphere during their ... . Treatment with extracorporeal membrane oxygenation may be required for many patients with influenza A (H1N1). JAMA. 2009;302(17).. Abstract
submitted by kickingbird at Oct, 13, 2009 from JAMA. 2009;302(17). (via http://www.infectiousdiseasenews.com/article/44496.aspx#)
One-third of young adult patients in Australia and New Zealand may have received extracorporeal membrane oxygenation to treat respiratory failure associated with influenza A (H1N1), according to findings ... US CDC. Bacterial Coinfections in Lung Tissue Specimens from Fatal Cases of 2009 Pandemic Influenza A (H1N1) --- United States, May--August 2009. MMWR Morb Mortal Wkly Rep 2009; 58 (early release). Abstract
submitted by kickingbird at Oct, 1, 2009 from MMWR Morb Mortal Wkly Rep 2009; 58 (early release) (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58e0929a1.htm?s_c)
In previous influenza pandemics, studies of autopsy specimens have shown that most deaths attributed to influenza A virus infection occurred concurrently with bacterial pneumonia (1), but such evidence ... MMWR. Oseltamivir-Resistant Novel Influenza A (H1N1) Virus Infection in Two Immunosuppressed Patients --- Seattle, Washington, 2009. MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4. Abstract
submitted by kickingbird at Aug, 16, 2009 from MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4 (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58d0814a1.htm?s_c)
Novel influenza A (H1N1) virus infection continues to cause illness and death among persons worldwide. Immunosuppressed patients with influenza virus infection can shed virus for prolonged periods, increasing ... Amesh A. Adalja. Zanamivir Resistance in Influenza. CBN. Abstract
submitted by kickingbird at Aug, 14, 2009 from CBN (via http://www.upmc-cbn.org/report_archive/2009/08_August_2009/c)
Antiviral therapy against influenza always has been plagued by the development of resistance. Unfortunately, as medical management of influenza relies increasingly on antiviral therapy, drug resistance ... Danishuddin M, Khan AU.. Phylogenetic Analysis of the Neuraminidase Gene Reveals that the H5N1 Strains Prevalent in Chickens During 2006 Bird Flu Outbreaks in Two Regions of Maharashtra, India Are Genetically Different. Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2. Abstract
submitted by kickingbird at Jul, 16, 2009 from Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2 (via http://www.ncbi.nlm.nih.gov/pubmed/19591792?ordinalpos=39&it)
In February 2006, two outbreaks of highly pathogenic avian influenza A virus subtype H5N1 occurred in chickens in two neighboring districts (first in Nandurbar and second in Jalgaon) of Maharashtra, India, ... van Zoelen MA, van der Sluijs KF, Achouiti A, Flor. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology. 2009 Jul 8. Abstract
submitted by kickingbird at Jul, 16, 2009 from Virology. 2009 Jul 8 (via http://www.ncbi.nlm.nih.gov/pubmed/19592063?ordinalpos=35&it)
Pneumonia caused by influenza A virus (IAV) can have devastating effects, resulting in respiratory failure and death. The idea that a new influenza pandemic might occur in the near future has triggered ... Lange E, Kalthoff D, Blohm U, Teifke JP, Breithaup. Pathogenesis and transmission of the novel swine origin influenza virus A/H1N1 after experimental infection of pigs. J Gen Virol. 2009 Jul 10.. Abstract
submitted by kickingbird at Jul, 16, 2009 from J Gen Virol. 2009 Jul 10. (via http://www.ncbi.nlm.nih.gov/pubmed/19592456?ordinalpos=33&it)
Influenza virus A/H1N1n currently causing a pandemic contains gene segments with ancestors in North American and Eurasian swine lineages. To get insights into virus replication dynamics, clinical symptoms ... Ilyinskii PO, Schmidt T, Lukashev D, Meriin AB, Th. Importance of mRNA Secondary Structural Elements for the Expression of Influenza Virus Genes. OMICS. 2009 Jul 13.. Abstract
submitted by kickingbird at Jul, 16, 2009 from OMICS. 2009 Jul 13. (via http://www.ncbi.nlm.nih.gov/pubmed/19594376?ordinalpos=28&it)
Development of novel vaccines and therapeutics often requires efficient expression of recombinant viral proteins. Here we show that mutations in essential functional regions of conserved influenza proteins ... Husain M, Harrod KS. Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells. FEBS Lett. 2009 Jul 10. Abstract
submitted by kickingbird at Jul, 16, 2009 from FEBS Lett. 2009 Jul 10 (via http://www.ncbi.nlm.nih.gov/pubmed/19596000?ordinalpos=24&it)
Histone deacetylase 6 (HDAC6) is a multi-substrate cytoplasmic enzyme that regulates many important biological processes. Recently, some reports have implicated HDAC6 in viral infection. However, nothing ... Yamanaka T, Nemoto M, Tsujimura K, Kondo T, Matsum. Interspecies transmission of equine influenza virus (H3N8) to dogs by close contact with experimentally infected horses. Vet Microbiol. 2009 Jun 21.. Abstract
submitted by kickingbird at Jul, 16, 2009 from Vet Microbiol. 2009 Jun 21. (via http://www.ncbi.nlm.nih.gov/pubmed/19596528?ordinalpos=20&it)
In horse populations, influenza A virus subtype H3N8 (equine influenza virus, EIV) is a very important pathogen that leads to acute respiratory disease. Recently, EIV has emerged in dogs, and has become ... Chan RW, Chan MC, Wong AC, Karamanska R, Dell A, H. DAS181 Inhibits H5N1 Influenza virus Infection of Human Lung Tissues. Antimicrob Agents Chemother. 2009 Jul 13. Abstract
submitted by kickingbird at Jul, 16, 2009 from Antimicrob Agents Chemother. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19596886?ordinalpos=14&it)
DAS181 is a novel therapeutic candidate against influenza virus which functions via the mechanism of removing the virus receptor, sialic acid (Sia) from the adjacent glycan structures. DAS181 and its analogues ... Smith GJ, Bahl J, Vijaykrishna D, Zhang J, Poon LL. Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A. 2009 Jul 13. Abstract
submitted by kickingbird at Jul, 16, 2009 from Proc Natl Acad Sci U S A. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19597152?ordinalpos=12&it)
Pandemic influenza viruses cause significant mortality in humans. In the 20th century, 3 influenza viruses caused major pandemics: the 1918 H1N1 virus, the 1957 H2N2 virus, and the 1968 H3N2 virus. These ... Vincent AL, Ma W, Lager KM, Gramer MR, Richt JA, J. Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States. Virus Genes. 2009 Jul 14. Abstract
submitted by kickingbird at Jul, 16, 2009 from Virus Genes. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19597980?ordinalpos=9&ito)
H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003-2004; antigenic and genetic characterization identified the hemagglutinin (HA) as ... 5181 items, 20/Page, Page[209/260][|<<] [|<] [201] [202] [203] [204] [205] [206] [207] [208] [209] [210] [>|] [>>|] |
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