Hongying Chen, etc.,al. [preprint]NSUN2-dependent 5-methylcytosine Modification Regulates Influenza A virus Gene Expression and Genomic Packaging. https://doi.org/10.1101/2025.11.26.690652. Abstract
submitted by kickingbird at 7 days ago from https://doi.org/10.1101/2025.11.26.690652 (via https://www.biorxiv.org/content/10.1101/2025.11.26.690652v1)
Emerging evidence indicates that methyltransferase NSUN2 catalyzes 5-methylcytosine (m5C) modifications on various viral RNAs and plays important roles in viral biology. However, the regulatory roles of ... Christopher Ruis, etc.,al. [preprint]Mutational spectra reveal influenza virus transmission routes and adaptation. https://doi.org/10.1101/2025.11.26.690773. Abstract
submitted by kickingbird at 7 days ago from https://doi.org/10.1101/2025.11.26.690773 (via https://www.biorxiv.org/content/10.1101/2025.11.26.690773v1)
Influenza A virus remains a major cause of morbidity and mortality in humans and animals with pandemic potential. While control of outbreaks and spillover events remains a key health priority, the transmission ... Wu Y, Long Y, Yang X, Du X, Du X, Zahan N, Deng Z,. Harnessing a Surface Water-Based Multifaceted Approach to Combat Zoonotic Viruses: A Rural Perspective from Bangladesh and China. Microorganisms. 2025; 13(11):2526. Abstract
submitted by kickingbird at 7 days ago from Microorganisms. 2025; 13(11):2526 (via https://www.mdpi.com/2076-2607/13/11/2526)
Rural tropical regions face escalating threats from zoonotic AIV and dengue virus but lack sewered infrastructure for conventional wastewater surveillance. We implemented surface water-based surveillance ... Turnbull ML, Wang Y, Clare S, Lieber G, Williams S. Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals. Science. 2025 Nov 27;390(6776):eadq4691. Abstract
submitted by kickingbird at 7 days ago from Science. 2025 Nov 27;390(6776):eadq4691 (via https://www.science.org/doi/10.1126/science.adq4691)
Host body temperature can define a virus's replicative profile-influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted to ... Guo J, Jung B, Yoon SW, Liu Y, Feng Z, Yeom M, Na. Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines. Virulence. 2025 Nov 27:2595767. Abstract
submitted by kickingbird at 7 days ago from Virulence. 2025 Nov 27:2595767 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2025.2)
The segmented nature and high mutability of the influenza virus RNA genome facilitate rapid mutation and reassortment, allowing the virus to breach host barriers and migrate between different species, ... Xiong W, Yin H, Gao L, Liang S. Global Trends in Influenza and Meningitis Research: A Comprehensive Bibliometric and Visualization Analysis (1980-2024). J Multidiscip Healthc. 2025 Nov 21;18:7609-7625. Abstract
submitted by kickingbird at 7 days ago from J Multidiscip Healthc. 2025 Nov 21;18:7609-7625 (via https://www.dovepress.com/global-trends-in-influenza-and-men)
Background: Influenza and meningitis are interconnected through shared epidemiological patterns and complications, with influenza often leading to bacterial meningitis by compromising host immunity. This ... Anselmo Vasconcelos Rivetti Jr, etc.,al. Genomic Diversity and Reassortment of Highly Pathogenic Avian Influenza A/H5N1 Virus (Clade 2.3.4.4b) in Brazil: Evidence of Multiple Introductions and Intra-Epidemic Reassortment in 2025. Virology. Abstract
submitted by kickingbird at 7 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Highly pathogenic avian influenza (HPAI) A/H5N1, clade 2.3.4.4b, has spread globally, with the first outbreak in a commercial poultry farm in Brazil reported in 2025. This study aimed to genetically characterize ... Chang Li. Genetic evolutionary dynamics and interspecies transmission risk of H9N2 subtype of avian influenza viruses. Animals and Zoonoses. Abstract
submitted by kickingbird at 7 days ago from Animals and Zoonoses (via https://www.sciencedirect.com/science/article/pii/S295024892)
Since its initial isolation from a turkey flock in Wisconsin, USA, in 1966, the H9N2 subtype of avian influenza virus (AIV) has emerged as a significant threat to the global poultry industry and human ... Shen W, Xu J, Chen Z, Wei Y, Wang Q, Wang X, Zhang. Broad-spectrum inhibition of influenza A virus replication by blocking the nuclear export of viral ribonucleoprotein complexes. J Virol 0:e01478-25. Abstract
submitted by kickingbird at 7 days ago from J Virol 0:e01478-25 (via https://journals.asm.org/doi/10.1128/jvi.01478-25)
Influenza A virus (IAV) remains a major threat to global health. The emergence of IAV strains resistant to commonly used anti-influenza medicines has made the need for novel broad-spectrum antiviral agents ... Cargnin Faccin, F., Gay, L.C., Regmi, D. et al. Sequential aerosol and oral immunization with a bivalent H9N2/H5N2 vaccine protects against H5N1 and H9N2 avian influenza challenges. npj Vaccines (2025). Abstract
submitted by kickingbird at 7 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01325-4)
Avian influenza continues to be a major threat to poultry and public health. This study investigated the efficacy of a bivalent H9N2/H5N2 modified live virus (MLV) vaccine delivered through a sequential ... Gopal AB, Lv H, Pholcharee T, Ouyang WO, Teo QW, L. Characterization of two non-competing antibodies to influenza H3N2 hemagglutinin stem reveals its evolving antigenicity. Nat Commun. 2025 Nov 26;16(1):10557. Abstract
submitted by kickingbird at 8 days ago from Nat Commun. 2025 Nov 26;16(1):10557 (via https://www.nature.com/articles/s41467-025-65595-1)
The conserved stem domain of influenza hemagglutinin (HA), which is classified into group 1 and group 2, is a target of broadly neutralizing antibodies. While many group 1 HA stem antibodies have been ... Shichinohe S, Hiono T, Itoh Y, Takada K, Kida Y, W. Characterization of H5N1 high pathogenicity avian influenza virus belonging to clade 2.3.4.4b isolated from Ezo red fox in Japan in a mouse model. Microbiol Spectr. 2025 Nov 26:e0109725. Abstract
submitted by kickingbird at 8 days ago from Microbiol Spectr. 2025 Nov 26:e0109725 (via https://journals.asm.org/doi/10.1128/spectrum.01097-25)
H5N1 high pathogenicity avian influenza virus (HPAIV) has spread in wild birds and poultry worldwide. H5N1 HPAIV belonging to the currently predominant clade 2.3.4.4b has infected not only birds but also ... Gary, E.N., Tursi, N.J., Hojecki, C.E. et al. Electroporation and LNP-mediated delivery of plasmid DNA-encoded H5N1 influenza virus hemagglutinin support protection against highly pathogenic avian influenza. npj Vaccines (2025). Abstract
submitted by kickingbird at 9 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01316-5)
Highly pathogenic avian influenzas (HPAIs) is a continuing public health threat. Here, we describe the development of plasmid-encoded H5N1 hemagglutinin antigens representing clades that have caused human ... European Food Safety Authority, etc.,al. Unprecedented high level of highly pathogenic avian influenza in wild birds in Europe during the 2025 autumn migration. EFSA Journal. Abstract
submitted by kickingbird at 9 days ago from EFSA Journal (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
Between 6 September and 14 November 2025, 1,443 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in wild birds across 26 countries in Europe. This number was four times higher ... Hye-Ryoung Kim, etc.,al. Comparison of Gross Lesions in Poultry Naturally Infected With High Pathogenicity Avian Influenza H5N6 and H5N1 Viruses in South Korea, 2023-2025. Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at 9 days ago from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1736453)
High pathogenicity avian influenza (HPAI) is an acute infectious disease of poultry and wild birds that has been occurring worldwide and has been controlled in many countries by culling birds on farms ... Larsen SV, Israelson R, Torp C, Larsen LE, Jensen. Transmission, Pathological and Clinical Manifestations of Highly Pathogenic Avian Influenza A Virus in Mammals with Emphasis on H5N1 Clade 2.3.4.4b. Viruses. 2025; 17(12):1548. Abstract
submitted by kickingbird at 9 days ago from Viruses. 2025; 17(12):1548 (via https://www.mdpi.com/1999-4915/17/12/1548)
Highly pathogenic avian influenza A virus (HPAIV) H5N1, clade 2.3.4.4b, has emerged as a significant zoonotic threat. H5N1 is widely circulating in wild birds, and an increasing number of spillover events ... Joel Armando Vazquez-Perez, etc.,al. [preprint]Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult. https://doi.org/10.1101/2025.11.21.25340167. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.1101/2025.11.21.25340167 (via https://www.medrxiv.org/content/10.1101/2025.11.21.25340167v)
Background Infection of backyard and poultry with low pathogenicity avian influenza LPAI A(H5N2) viruses has occurred in Mexico since 1994, and the first human infection caused by this influenza virus ... Zhang X, Lam SJ, Chen LL, Fong CH, Chan WM, Ip JD,. Avian influenza virus A(H5N1) genotype D1.1 is better adapted to human nasal and airway organoids than genotype B3.13. J Infect Dis. 2025 Nov 24:jiaf598. Abstract
submitted by kickingbird at 9 days ago from J Infect Dis. 2025 Nov 24:jiaf598 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Three critically ill or fatal avian influenza A(H5N1) human infections have been reported in North America since November 2024. Notably, all were infected with genotype D1.1 instead of B3.13, the dominant ... Huang QJ, McDaniel CN, Griffith AA, Schiffer CA, S. Subnanometer-resolution Structural Determination of Hemagglutinin from Cryo-electron Tomography of Influenza Viruses. J Vis Exp. 2025 Nov 7;(225). Abstract
submitted by kickingbird at 9 days ago from J Vis Exp. 2025 Nov 7;(225) (via https://app.jove.com/t/68636/subnanometer-resolution-structu)
Cryo-electron tomography is a powerful tool to visualize heterogeneous samples, with one major application being structural characterization of pleomorphic viruses. In recent years, subtomogram averaging ... Chalkowski K, Miller RS, Chandler JC, Campos A, Ar. Elevated Exposure to Influenza A Viruses in Wild Pigs (Sus scrofa), Texas, USA. J Wildl Dis. 2025 Nov 25. Abstract
submitted by kickingbird at 9 days ago from J Wildl Dis. 2025 Nov 25 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
Detections of highly pathogenic avian influenza viruses in mammals have increased globally, underscoring the need to assess influenza A virus (IAV) exposure in species that bridge wildlife, livestock, ... 6469 items, 20/Page, Page[2/324][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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