Wu, Y. et al.. A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus. Nature Communications. Abstract
submitted by kickingbird at Jul, 28, 2015 from Nature Communications (via http://www.nature.com/ncomms/2015/150721/ncomms8708/full/nco)
Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here ... MEDINA J, Boukhebza H, De Saint Jean A, Sodoyer R,. Optimization of influenza A vaccine virus by reverse genetic using chimeric HA and NA genes with an extended PR8 backbone. Vaccine. 2015 Jul 20. pii: S0264-410X(15)00981-0.. Abstract
submitted by kickingbird at Jul, 27, 2015 from Vaccine. 2015 Jul 20. pii: S0264-410X(15)00981-0. (via http://www.ncbi.nlm.nih.gov/pubmed/26206270)
The yield of influenza antigen may significantly vary between vaccine strains; for example the A/California/07/09 (H1N1)-X179A vaccine virus, prepared during 2009 influenza pandemic, presented a low antigen ... DLUGOLENSKI D, Jones L, Howerth E, Wentworth D, et. Swine Influenza Virus PA and Neuraminidase Gene Reassortment into Human H1N1 Influenza Virus Is Associated with an Altered Pathogenic Phenotype Linked to Increased MIP-2 Expression. J Virol. 2015 May;89(10):5651-67.. Abstract
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 May;89(10):5651-67. (via http://www.ncbi.nlm.nih.gov/pubmed/25762737)
Swine are susceptible to infection by both avian and human influenza viruses, and this feature is thought to contribute to novel reassortant influenza viruses. In this study, the influenza virus reassortment ... VER LS, Marcos-Villar L, Landeras-Bueno S, Nieto A. The cellular factor NXP2/MORC3 is a positive regulator for influenza virus multiplication. J Virol. 2015 Jul 22. pii: JVI.01530-15.. Abstract
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01530-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26202233)
Transcription and replication of the influenza A virus are carried out in the nucleus of the infected cells in the context of viral ribonucleoproteins (RNPs). The viral polymerase responsible for these ... SHIN DL, Hatesuer B, Bergmann S, Nedelko T, et al. Protection from severe influenza infections in mice carrying the Mx1 influenza resistance gene strongly depends on genetic background. J Virol. 2015 Jul 22. pii: JVI.01305-15. Abstract
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01305-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202236)
Influenza infections represent a serious threat to human health. Both extrinsic and intrinsic factors determine the severity of influenza disease. The MX dynamin-like GTPase 1 (Mx1) gene has been shown ... LUK GS, Leung CY, Sia SF, Choy KT, et al. Transmission of H7N9 influenza viruses with polymorphism at PB2 residue 627 in chickens and ferrets. J Virol. 2015 Jul 22. pii: JVI.01444-15. Abstract
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01444-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202239)
Poultry exposure is a major risk factor for human H7N9 zoonotic infections of which the mode of transmission remains unclear. We studied the transmission of genetically related poultry and human H7N9 influenza ... WATSON SJ, Langat P, Reid SM, Lam TT, et al. Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013. J Virol. 2015 Jul 22. pii: JVI.00840-15. Abstract
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.00840-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202246)
The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus of swine origin, highlighted the importance of worldwide influenza virus surveillance in swine. To date, large-scale ... LERSRITWIMANMAEN P, Na-Ek P, Thanunchai M, Thewsoo. The presence of monocytes enhances the susceptibility of B cells to highly pathogenic avian influenza (HPAI) H5N1 virus possibly through the increased expression of α2,3 SA receptor. Biochem Biophys Res Commun. 2015 Jul 15.. Abstract
submitted by kickingbird at Jul, 27, 2015 from Biochem Biophys Res Commun. 2015 Jul 15. (via http://www.ncbi.nlm.nih.gov/pubmed/26187669)
The highly pathogenic avian influenza (HPAI) H5N1 virus causes severe systemic infection in avian and mammalian species, including humans by first targeting immune cells. This subsequently renders the ... Arriola CS, Nelson DI, Deliberto TJ, Blanton L, Kn. Infection Risk for Persons Exposed to Highly Pathogenic Avian Influenza A H5 Virus–Infected Birds, United States, December 2014–March 2015. Emerg Infect Dis. 2015 Dec. Abstract
submitted by kickingbird at Jul, 25, 2015 from Emerg Infect Dis. 2015 Dec (via http://wwwnc.cdc.gov/eid/article/21/12/15-0904_article)
Newly emerged highly pathogenic avian influenza (HPAI) A H5 viruses have caused outbreaks among birds in the United States. These viruses differ genetically from HPAI H5 viruses that previously caused ... Nelson MI, Schaefer R, Gava D, Cant?o ME, Ciacci-Z. Influenza A Viruses of Human Origin in Swine, Brazil. Emerg Infect Dis. 2015 Aug. Abstract
submitted by kickingbird at Jul, 20, 2015 from Emerg Infect Dis. 2015 Aug (via http://wwwnc.cdc.gov/eid/article/21/8/14-1891_article)
The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American ... BAO H, Ma Y, Shi J, Zeng X, et al. Evaluation and application of a one-step duplex real-time reverse transcription polymerase chain reaction assay for the rapid detection of influenza A (H7N9) virus from poultry samples. Arch Virol. 2015 Jul 16.. Abstract
submitted by kickingbird at Jul, 20, 2015 from Arch Virol. 2015 Jul 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26179621)
In China, a novel reassortant influenza A (H7N9) virus, which has caused 435 cases of human infection, has recently emerged. Most cases of human infections with the H7N9 virus are known to be associated ... XIONG X, Corti D, Liu J, Pinna D, et al. Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody. Proc Natl Acad Sci U S A. 2015 Jul 13. pii: 201510. Abstract
submitted by kickingbird at Jul, 20, 2015 from Proc Natl Acad Sci U S A. 2015 Jul 13. pii: 201510 (via http://www.ncbi.nlm.nih.gov/pubmed/26170284)
H5N1 avian influenza viruses remain a threat to public health mainly because they can cause severe infections in humans. These viruses are widespread in birds, and they vary in antigenicity forming three ... ZHANG XC, Liu S, Hou GY, Zhuang QY, et al. Comparison of three media for transport and storage of the samples collected for detection of avian influenza virus. J Virol Methods. 2015 Jul 6;222:202-205. Abstract
submitted by kickingbird at Jul, 20, 2015 from J Virol Methods. 2015 Jul 6;222:202-205 (via http://www.ncbi.nlm.nih.gov/pubmed/26159628)
Detection of avian influenza viruses (AIVs) is important for diagnosis, surveillance and control of avian influenza which is of great economic and public health significance. Proper transport and storage ... VAN DER VRIES E, Ip DK, Cowling BJ, Zhang JD, et a. Outcomes and Susceptibility to Neuraminidase Inhibitors in Individuals Infected with Different Influenza B Lineages: the Influenza Resistance Information Study. J Infect Dis. 2015 Jul 9. pii: jiv375. Abstract
submitted by kickingbird at Jul, 20, 2015 from J Infect Dis. 2015 Jul 9. pii: jiv375 (via http://www.ncbi.nlm.nih.gov/pubmed/26160744)
BACKGROUND:
?Little is known about how influenza infections caused by B/Victoria and B/Yamagata virus lineages compare with respect to disease course and susceptibility to antiviral therapy.
METHODS: ... KWIT K, Pomorska-Mol M, Markowska-Daniel I. Pregnancy outcome and clinical status of gilts following experimental infection by H1N2, H3N2 and H1N1pdm09 influenza A viruses during the last month of gestation. Arch Virol. 2015 Jul 11. Abstract
submitted by kickingbird at Jul, 20, 2015 from Arch Virol. 2015 Jul 11 (via http://www.ncbi.nlm.nih.gov/pubmed/26162303)
The present study was planned to study the effect of various subtypes of swine influenza virus (SIV) circulating among pigs (H1N2, H3N2 and emerging pandemic strain of H1N1 influenza A virus (H1N1pdm09) ... RIDENOUR C, Williams SM, Jones L, Tompkins SM, et. Serial passage in ducks of a low-pathogenic avian influenza virus isolated from a chicken reveals a high mutation rate in the hemagglutinin that is likely due to selection in the host. Arch Virol. 2015 Jul 16.. Abstract
submitted by kickingbird at Jul, 20, 2015 from Arch Virol. 2015 Jul 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26179620)
A comparative study of the ability of three low-pathogenic avian influenza virus (LPAIV) isolates to be transmitted from duck to duck was performed. Pekin ducks were inoculated with two LPAIV isolates ... PAN M, Gao R, Lu Q, Huang S, et al. Human infection with a novel highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings. J Infect 2015 Jul 1. pii: S0163-4453(15)00220. Abstract
submitted by kickingbird at Jul, 11, 2015 from J Infect 2015 Jul 1. pii: S0163-4453(15)00220 (via http://www.ncbi.nlm.nih.gov/m/pubmed/26143617/)
OBJECTIVES: Human severe infection with avian influenza A (H5N6) virus infection was identified firstly in 2014 in China. It was unknown or unclear on the disease or the pathogen by people. This study ... ZHOU X, Li Y, Wang Y, Edwards J, et al. The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A (H7N9): a cross-sectional observational study in four eastern China provinces. J Infect. 2015 Jul 3. pii: S0163-4453(15)00223-6.. Abstract
submitted by kickingbird at Jul, 11, 2015 from J Infect. 2015 Jul 3. pii: S0163-4453(15)00223-6. (via http://www.ncbi.nlm.nih.gov/pubmed/26149187)
BACKGROUND:
A new reassortant influenza A (H7N9) virus emerged early 2013 in eastern China. Exposure to H7N9 infected poultry at live bird markets (LBM) was implicated as the main risk factor for human ... Fujimoto Y, Ito H, Tomita M, Ono E, et al.. Amino acid substitution at position 44 of matrix protein 2 of an avirulent H5 avian influenza virus is crucial for acquiring the highly pathogenic phenotype in chickens. Arch Virol 2015.. Abstract
submitted by kickingbird at Jul, 5, 2015 from Arch Virol 2015. (via http://www.ncbi.nlm.nih.gov/m/pubmed/26081872/)
The pathogenicity of highly pathogenic avian influenza (HPAI) viruses is dependent on multiple factors, but the sequence at the HA cleavage site plays the most important role. To better understand the ... Gnirss K, Zmora P, Blazejewska P, Winkler M, et al. Tetherin sensitivity of influenza A viruses is strain specific: Role of hemagglutinin and neuraminidase. J Virol 2015 Jun 24. pii: JVI.00615. Abstract
submitted by kickingbird at Jul, 5, 2015 from J Virol 2015 Jun 24. pii: JVI.00615 (via http://www.ncbi.nlm.nih.gov/m/pubmed/26109730/)
The expression of the antiviral host cell factor tetherin is induced by interferon and can inhibit the release of enveloped viruses from infected cells. The Vpu protein of HIV-1 antagonizes the antiviral ... 5156 items, 20/Page, Page[171/258][|<<] [|<] [171] [172] [173] [174] [175] [176] [177] [178] [179] [180] [>|] [>>|] |
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