Sownthirarajan B, Mason M, Loganathan G, Manivasag. A versatile H5N1-VSV platform for safe influenza virus research applications. J Virol 0:e00975-25. Abstract submitted by kickingbird at Aug, 9, 2025 from J Virol 0:e00975-25 (via https://journals.asm.org/doi/10.1128/jvi.00975-25) The H5N1 strain of influenza A virus (IAV) continues to cause severe infections in a range of avian and mammalian species, including sporadic but concerning cases in humans. There is growing concern that ... Pauline M van Diemen, etc.,al. [preprint]Experimental infection of alpacas (Vicugna pacos) with Influenza C and D viruses results in subclinical upper respiratory tract disease. https://doi.org/10.1101/2025.07.28.667103. Abstract submitted by kickingbird at Aug, 9, 2025 from https://doi.org/10.1101/2025.07.28.667103 (via https://www.biorxiv.org/content/10.1101/2025.07.28.667103v1) Influenza D virus (IDV), a new genus within the Orthomyxoviridae family, was initially detected in pigs and cattle. IDV is structurally similar to influenza C virus (ICV). Influenza A, C and D viruses ... Carrie L. Byington, Donald Pizzo, Hana Russo, Stev. [preprint]Sialic Acid Receptors in Human Mammary Tissue: Implications for Infection with Novel Influenza Strains. https://doi.org/10.1101/2025.08.06.25333154. Abstract submitted by kickingbird at Aug, 9, 2025 from https://doi.org/10.1101/2025.08.06.25333154 (via https://www.medrxiv.org/content/10.1101/2025.08.06.25333154v) Importance: Highly pathogenic avian influenza (HPAI) A H5N1 has been recognized for nearly three decades as a threat to avian species and as a virus with pandemic potential if spillover into human populations ... Zanin M, Flerlage T, Wong S, Vogel P, Piza K, Schr. Inflammatory, transcriptomic, and cell fate responses underlying the mammalian transmission of avian influenza viruses. J Virol 0:e00647-25. Abstract submitted by kickingbird at Aug, 9, 2025 from J Virol 0:e00647-25 (via https://journals.asm.org/doi/10.1128/jvi.00647-25) Airborne transmissibility of avian influenza viruses (AIVs) in humans is considered an essential component of their pandemic risk. Although several viral factors regulating airborne transmission (AT) have ... Liu Z, Zhang L, Zhang W, Lai Y, Deng T. The 5′-end segment-specific noncoding region of influenza A virus regulates both competitive multi-segment RNA transcription and selective genome packaging during infection. J Virol 0:e00328-25. Abstract submitted by kickingbird at Aug, 7, 2025 from J Virol 0:e00328-25 (via https://journals.asm.org/doi/10.1128/jvi.00328-25) The 3′ and 5′ termini of the eight RNA segments of the influenza A virus (IAV) genome contain segment-specific or subtype-specific (in HA and NA segments) noncoding regions (ssNCRs), located between the ... Hammed Olawale Fatoyinbo, Parul Tiwari, Ryan H.L.. Multivariable analysis of highly pathogenic H5N1 and H5Nx avian influenza in wild birds and poultry in Asian subregions. Comparative Immunology, Microbiology and Infectiou. Abstract submitted by kickingbird at Aug, 7, 2025 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/pii/S014795712) The spread of highly pathogenic avian influenza (HPAI) virus in wild birds, poultry, and other livestock worldwide has caused great concerns, especially in Asia, where the migration routes of many wild ... Sooksawasdi Na Ayudhya S, Leijten L, Rijnink WF, S. Attachment Patterns of Avian Influenza H5 Clade 2.3.4.4b Virus in Respiratory Tracts of Marine Mammals, North Atlantic Ocean. Emerg Infect Dis. 2025 Sep. Abstract submitted by kickingbird at Aug, 7, 2025 from Emerg Infect Dis. 2025 Sep (via https://wwwnc.cdc.gov/eid/article/31/9/25-0499_article) Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infections have caused substantial mortality events in marine mammals in recent years. We hypothesized that the high number of infections ... Aslam S, Sánchez-Aparicio MT, Siempelkamp BD, Dorn. Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation. Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e242. Abstract submitted by kickingbird at Aug, 6, 2025 from Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e242 (via https://www.pnas.org/doi/10.1073/pnas.2423066122) The nonstructural protein 1 (NS1) of influenza A virus performs a broad variety of proviral activities in the infected cell, primarily mediating evasion from the host innate immune response by being the ... Cavicchio L, Tassoni L, Pastori A, Carrino M, Gagl. Swine influenza surveillance in Italy uncovers regional and farm-based genetic clustering. Front Microbiol. 2025 Jul 21;16:1607204. Abstract submitted by kickingbird at Aug, 6, 2025 from Front Microbiol. 2025 Jul 21;16:1607204 (via https://www.frontiersin.org/journals/microbiology/articles/1) Introduction: Swine Influenza is a respiratory disease endemic in pigs with implications for animal and public health. Pigs, as mixing vessels for human, avian, and swine influenza strains, contribute ... Jumpei Ito, etc.,al. [preprint]Integrative modeling of seasonal influenza evolution via AI-powered antigenic cartography. https://doi.org/10.1101/2025.08.04.668423. Abstract submitted by kickingbird at Aug, 6, 2025 from https://doi.org/10.1101/2025.08.04.668423 (via https://www.biorxiv.org/content/10.1101/2025.08.04.668423v1) Seasonal influenza viruses evade host immunity through rapid antigenic evolution. Antigenicity is assessed by serological assays and typically visualized as antigenic maps, which represent antigenic differences ... Chan JCM, Ching RHH, Kock HHM, Long T, Nicholls JM. Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using ex vivo and in vitro cultures of the human respiratory tract. J Gen Virol. 2025 Jul;106(7):002133. Abstract submitted by kickingbird at Aug, 4, 2025 from J Gen Virol. 2025 Jul;106(7):002133 (via https://www.microbiologyresearch.org/content/journal/jgv/10.) Recent studies have reported a genotype 4 (G4) reassortant Eurasian avian-like (EA) H1N1 virus in swine, demonstrating a potential pandemic threat in humans. Here, we have compared the tropism, replication ... Jo, G., Yamayoshi, S., Ma, K.M. et al. Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3. Nat Commun 16, 7067 (2025). Abstract submitted by kickingbird at Aug, 3, 2025 from Nat Commun 16, 7067 (2025) (via https://link.springer.com/article/10.1038/s41467-025-62174-2) Influenza viruses evolve rapidly, driving seasonal epidemics and posing global pandemic threats. While neuraminidase (NA) has emerged as a vaccine target, shared molecular features of NA antibody responses ... Mansi Sharma, etc.,al. [preprint]Differential modulation of Interferon and Cell Death Responses defines Human vs Avian Influenza A Virus Strain-Specific Virulence and guides Combination Therapy. https://doi.org/10.1101/2025.07.31.667854. Abstract submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.31.667854 (via https://www.biorxiv.org/content/10.1101/2025.07.31.667854v1) Influenza A virus (IAV) poses a significant global health risk, with highly pathogenic strains like H5N1 (CFR ~52%) causing severe disease compared to less lethal but more transmissible strains like H1N1 ... Mark A. Power, etc.,al. [preprint]Seasonal Influenza Exposure Elicits Functional Antibody and T-cell Responses to A(H5) Influenza Viruses in Humans. https://doi.org/10.1101/2025.07.31.25331995. Abstract submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.31.25331995 (via https://www.medrxiv.org/content/10.1101/2025.07.31.25331995v) Background Highly pathogenic avian influenza A(H5) viruses pose a pandemic threat, with a history of zoonotic spillovers into humans that are presumed immunologically na?ve. Whether the general population ... Oluwatosin Babasola, Mohamed Bakheet, Christina Na. [preprint]A Phylogeny-Informed Mathematical Modeling of H5N1 Transmission Dynamics and Effectiveness of Control Measures. https://doi.org/10.1101/2025.07.29.25331913. Abstract submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.29.25331913 (via https://www.medrxiv.org/content/10.1101/2025.07.29.25331913v) The highly pathogenic avian influenza (HPAI) subtype H5N1 is a severe viral disease which continues to pose a significant threat to public health and a rigorous understanding of its transmission dynamics ... Lv K, Li X, Zhu X, Cai JP, Liu S, Sun Y, Liu L, Ca. Broad neuraminidase antibodies confer protection against seasonal and avian influenza viruses. Nat Commun. 2025 Aug 2;16(1):7103. Abstract submitted by kickingbird at Aug, 3, 2025 from Nat Commun. 2025 Aug 2;16(1):7103 (via https://www.nature.com/articles/s41467-025-62040-1) Neuraminidase (NA) is a critical target for universal influenza vaccines and therapeutic antibodies, yet its antigenic landscape remains incompletely understood. Here we identify two broadly cross-protective ... Kozawa F, Tamura T, Takahashi N, Kakizuka T, Ichim. The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection. Cell Commun Signal. 2025 Aug 2;23(1):361. Abstract submitted by kickingbird at Aug, 3, 2025 from Cell Commun Signal. 2025 Aug 2;23(1):361 (via https://biosignaling.biomedcentral.com/articles/10.1186/s129) Background: Influenza A viruses (IAVs) initially infect a few host cells before spreading to neighboring cells. However, the molecular mechanisms underlying this dissemination remain unclear. We have previously ... Bayoumi M, Barre RS, Escobedo RA, Shivanna V, Jack. Identification of Amino Acid Residues in polymerase PB2 Responsible for Differential Replication and Pathogenicity of Avian Influenza Virus H5N1 Isolated from Human and Cattle in Texas, US. Emerg Microbes Infect. 2025 Aug 1:2542247. Abstract submitted by kickingbird at Aug, 3, 2025 from Emerg Microbes Infect. 2025 Aug 1:2542247 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2) Highly pathogenic avian influenza viruses (HPAIV) pose a serious public health concern. In March 2024, a first-time outbreak of HPAIV H5N1 in dairy cattle herds was reported in the United States (US). ... Annie Dosey, etc.,al. [preprint]Stabilization of H5 highly pathogenic avian influenza hemagglutinin improves vaccine-elicited neutralizing antibody responses. https://doi.org/10.1101/2025.07.30.667762. Abstract submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.30.667762 (via https://www.biorxiv.org/content/10.1101/2025.07.30.667762v1) Transmission of highly pathogenic avian influenza from H5 clade 2.3.4.4b has expanded in recent years to infect large populations of birds and mammals, heightening the risk of a human pandemic. Influenza ... Rongye Ye, Lun Li, Shuhui Song. [preprint]Influ-BERT: An Interpretable Model for Enhancing Low-Frequency Influenza A virus Subtype Recognition. https://doi.org/10.1101/2025.07.31.667841. Abstract submitted by kickingbird at Aug, 3, 2025 from https://doi.org/10.1101/2025.07.31.667841 (via https://www.biorxiv.org/content/10.1101/2025.07.31.667841v1) Influenza A Virus (IAV) poses a continuous threat to global public health due to its wide host adaptability, high-frequency antigenic variation, and potential for cross-species transmission. Accurate recognition ... 6469 items, 20/Page, Page[17/324][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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