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2024-5-9 8:09:51
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Kyra H. Grantz, etc.,al. Disparities in influenza mortality and transmission related to sociodemographic factors within Chicago in the pandemic of 1918. PNAS November 29, 2016.  Abstract  
submitted by kickingbird at Dec, 31, 2016 from PNAS November 29, 2016 (via http://www.pnas.org/content/113/48/13839)
The pervasiveness of influenza among humans and its rapid spread during pandemics create a false sense that all humans are affected equally. In this work, we show that neighborhood-level social determinants ...

Paola CR, etc., al. Whole-Genome Characterization of a Novel Human Influenza A(H1N2) Virus Variant, Brazil. DOI: 10.3201/eid2301.161122.  Abstract  
submitted by kickingbird at Dec, 31, 2016 from DOI: 10.3201/eid2301.161122 (via https://wwwnc.cdc.gov/eid/article/23/1/16-1122_article)
We report the characterization of a novel reassortant influenza A(H1N2) virus not previously reported in humans. Recovered from a a pig farm worker in southeast Brazil who had influenza-like illness, this ...

Leung, Kathy et al.. Monitoring the fitness of antiviral-resistant influenza strains during an epidemic: a mathematical modelling study. The Lancet Infectious Diseases.  Abstract  
submitted by kickingbird at Dec, 13, 2016 from The Lancet Infectious Diseases (via http://www.thelancet.com/journals/laninf/article/PIIS1473-30)
Background Antivirals (eg, oseltamivir) are important for mitigating influenza epidemics. In 2007, an oseltamivir-resistant influenza seasonal A H1N1 strain emerged and spread to global fixation within ...

Yi Hu, Peng Xu, Jing Luo, Hongxuan He, and Wenbin. Absolute Quantification of H5-subtype Avian Influenza Viruses Using Droplet Digital Loop-mediated Isothermal Amplification. Anal. Chem.,.  Abstract  
submitted by kickingbird at Dec, 12, 2016 from Anal. Chem., (via http://pubs.acs.org/doi/abs/10.1021/acs.analchem.6b03328)
Human infection with avian influenza A H5N1 viruses can cause severe diseases with high mortality rate, and continues to pose a significant threat to global public health. Rapid diagnosis is needed for ...

Jihui Ping, etc.,al. Development of high-yield influenza B virus vaccine viruses. PNAS.  Abstract  
submitted by kickingbird at Dec, 8, 2016 from PNAS (via http://www.pnas.org/content/early/2016/11/29/1616530113.abst)
The burden of human infections with influenza A and B viruses is substantial, and the impact of influenza B virus infections can exceed that of influenza A virus infections in some seasons. Over the past ...

Arafa, A.-S. et al. Risk assessment of recent Egyptian H5N1 influenza viruses. Scientific Reports 6, Article number: 38388 (2016).  Abstract  
submitted by kickingbird at Dec, 8, 2016 from Scientific Reports 6, Article number: 38388 (2016) (via http://www.nature.com/articles/srep38388)
Highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype are enzootic in poultry populations in different parts of the world, and have caused numerous human infections in recent years, particularly ...

Yuhai Bi, etc.,al. Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China. Cell Host & Microbe.  Abstract  
submitted by kickingbird at Dec, 3, 2016 from Cell Host & Microbe (via http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(16)
Constant surveillance of live poultry markets (LPMs) is currently the best way to predict and identify emerging avian influenza viruses (AIVs) that pose a potential threat to public health. Through surveillance ...

LI Ruifang, etc.,al. Influence of Synonymous Codon Bias on the RNA Secondary Structure in Influenza A Viruses. Chinese Journal of Virology.  Abstract  
submitted by kickingbird at Dec, 1, 2016 from Chinese Journal of Virology (via http://www.cnki.net/KCMS/detail/11.1865.R.20161130.2255.028.)
Abstract: Influenza-A viruses were selected as samples. Then, the relationship between synonymous codon bias and mRNA secondary structures was analyzed. Our data will provide a theoretical basis for further ...

ZHENG D, Chen S, Qu D, Chen J, et al.. Influenza H7N9 LAH-HBc virus-like particle vaccine with adjuvant protects mice against homologous and heterologous influenza viruses. Vaccine. 2016 Nov 17..  Abstract  
submitted by kickingbird at Nov, 27, 2016 from Vaccine. 2016 Nov 17. (via https://www.ncbi.nlm.nih.gov/pubmed/27866773)
The long alpha-helix (LAH) region located in influenza virus hemagglutinin (HA) shows conservation among different influenza A strains, which could be used as a candidate target of influenza vaccines. ...

EL-SHESHENY R, Mostafa A, Kandeil A, Mahmoud SH, e. Biological characterization of highly pathogenic avian influenza H5N1 viruses that infected humans in Egypt in 2014-2015. Arch Virol. 2016 Nov 18.  Abstract  
submitted by kickingbird at Nov, 27, 2016 from Arch Virol. 2016 Nov 18 (via https://www.ncbi.nlm.nih.gov/pubmed/27864633)
Highly pathogenic avian influenza (HPAI) H5N1 influenza viruses emerged as a human pathogen in 1997 with expected potential to undergo sustained human-to-human transmission and pandemic viral spread. HPAI ...

SHITTU I, Meseko CA, Gado DA, Olawuyi AK, et al. Highly pathogenic avian influenza (H5N1) in Nigeria in 2015: evidence of widespread circulation of WA2 clade 2.3.2.1c. Arch Virol. 2016 Nov 21.  Abstract  
submitted by kickingbird at Nov, 27, 2016 from Arch Virol. 2016 Nov 21 (via https://www.ncbi.nlm.nih.gov/pubmed/27873070)
Genetic analysis of the complete haemagglutinin (HA) gene of fourteen Nigerian avian influenza isolates showed multiple basic amino acids at the cleavage site (321PQRERRRK del R*GLF333), characteristic ...

ZANIN M, Kocer ZA, Poulson RL, Gabbard JD, et al. The Potential for Low Pathogenic Avian H7 Influenza A Viruses to Replicate and Cause Disease in a Mammalian Model. J Virol. 2016 Nov 16. pii: JVI.01934-16.  Abstract  
submitted by kickingbird at Nov, 20, 2016 from J Virol. 2016 Nov 16. pii: JVI.01934-16 (via https://www.ncbi.nlm.nih.gov/pubmed/27852855)
H7 subtype influenza A viruses are widely distributed and have been responsible for human infections and numerous outbreaks in poultry with significant impact. Despite this, the disease-causing potential ...

MINAKUCHI M, Sugiyama K, Kato Y, Naito T, et al. Pre-mRNA processing factor Prp18 is a stimulatory factor of influenza virus RNA synthesis and possesses the NP chaperone activity. J Virol. 2016 Nov 16..  Abstract  
submitted by kickingbird at Nov, 20, 2016 from J Virol. 2016 Nov 16. (via https://www.ncbi.nlm.nih.gov/pubmed/27852861)
The genome of influenza virus (vRNA) is associated with nucleoprotein (NP) and viral RNA-dependent RNA polymerases, and forms helical viral ribonucleoprotein (vRNP) complexes. NP-vRNA complex is the biologically ...

QU X, Ding X, Duan M, Yang J, et al. Influenza virus infection induces translocation of apoptosis-inducing factor (AIF) in A549 cells: role of AIF in apoptosis and viral propagation. Arch Virol. 2016 Nov 16.  Abstract  
submitted by kickingbird at Nov, 20, 2016 from Arch Virol. 2016 Nov 16 (via https://www.ncbi.nlm.nih.gov/pubmed/27853862)
It is recognized that influenza virus induces caspase-dependent apoptosis by activating caspase-3. Apoptosis-inducing factor (AIF) is a caspase-independent cell death effector, and its mitochondrial-nuclear ...

TU V, Abed Y, Barbeau X, Carbonneau J, et al. The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral. Antiviral Res. 2016 Nov 9;.  Abstract  
submitted by kickingbird at Nov, 20, 2016 from Antiviral Res. 2016 Nov 9; (via https://www.ncbi.nlm.nih.gov/pubmed/27838351)
Emergence of pan neuraminidase inhibitor (NAI)-resistant variants constitutes a serious clinical concern. An influenza A(H1N1)pdm09 variant containing the I427T/Q313R neuraminidase (NA) substitutions was ...

GONZALEZ Y, Juarez E, Carranza C, Sada E, et al. Diminished effector and memory CD8+ circulating T lymphocytes in patients with severe influenza caused by the AH1N1 pdm09 virus. Virology. 2016 Nov 2;500:139-148..  Abstract  
submitted by kickingbird at Nov, 16, 2016 from Virology. 2016 Nov 2;500:139-148. (via https://www.ncbi.nlm.nih.gov/pubmed/27816639)
The T cell immune response to viral infection includes the expansion of na?ve T cells, effector cell differentiation and the induction of long-lived memory cells. We compared the differentiation of CD8+ ...

GUJJAR N, Chothe SK, Gawai S, Nissly R, et al. Co-expression of sialic acid receptors compatible with avian and human influenza virus binding in emus (Dromaius novaehollandiae). Virology. 2016 Oct 28;500:114-121.  Abstract  
submitted by kickingbird at Nov, 16, 2016 from Virology. 2016 Oct 28;500:114-121 (via https://www.ncbi.nlm.nih.gov/pubmed/27816637)
Influenza A viruses (IAVs) continue to threaten animal and human health with constant emergence of novel variants. While aquatic birds are a major reservoir of most IAVs, the role of other terrestrial ...

KOSIK I, Yewdell JW. Influenza A virus hemagglutinin specific antibodies interfere with virion neuraminidase activity via two distinct mechanisms. Virology. 2016 Nov 5;500:178-183.  Abstract  
submitted by kickingbird at Nov, 16, 2016 from Virology. 2016 Nov 5;500:178-183 (via https://www.ncbi.nlm.nih.gov/pubmed/27825034)
We studied the ability of monoclonal Abs (mAbs) recognizing the major hemagglutinin (HA) antigenic sites to inhibit neuraminidase (NA) cleavage of sialic acids on fetuin. We show that virion associated-NA ...

JANSEN CA, van Haarlem DA, Sperling B, van Kooten. Identification of an Activating Chicken Ig-like Receptor Recognizing Avian Influenza Viruses. J Immunol. 2016 Nov 7..  Abstract  
submitted by kickingbird at Nov, 16, 2016 from J Immunol. 2016 Nov 7. (via https://www.ncbi.nlm.nih.gov/pubmed/27821665)
Chicken Ig-like receptors (CHIRs) represent a multigene family encoded by the leukocyte receptor complex that encodes a variety of receptors that are subdivided into activating CHIR-A, inhibitory CHIR-B, ...

Wang H. et al. Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China. BMC Infect Dis. 2016 Oct 3;16(1):534.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from BMC Infect Dis. 2016 Oct 3;16(1):534 (via http://bmcinfectdis.biomedcentral.com/articles/10.1186/s1287)
AbstractBackground: Guangzhou reported its first laboratory-confirmed case of influenza A (H7N9) on January 10, 2014. Atotal of 25 cases were reported from the first wave of the epidemic until April 8, ...

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