Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal. Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine 2017 Jun 22. Abstract
submitted by kickingbird at Jul, 3, 2017 from Vaccine 2017 Jun 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28648546/)
Influenza virus dominant antigens presentation using virus like particle (VLP) approach is attractive for the development of new generation of influenza vaccines. Mammalian cell platform offers many advantages ... Diaz A, Marthaler D, Culhane M, Sreevatsan S, et a. Complete Genome Sequencing of Influenza A Viruses within Swine Farrow-to-Wean Farms Reveals the Emergence, Persistence, and Subsidence of Diverse Viral Genotypes. J Virol 2017 Jun 28. Abstract
submitted by kickingbird at Jul, 3, 2017 from J Virol 2017 Jun 28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28659482/)
Influenza A viruses (IAVs) are endemic in swine and represent a public health risk. However, there is limited information on the genetic diversity of swine IAVs within farrow-to-wean farms, which is where ... Nam JH, Shim SM, Song EJ, Espano E, et al. Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice. Arch Virol 2017 Jun 29. Abstract
submitted by kickingbird at Jul, 3, 2017 from Arch Virol 2017 Jun 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28664296/)
Influenza A viruses must undergo adaptation to acquire virulence in new host species. In mouse models, host adaptation for virulence is generally performed through 5 to 20 lung-to-lung passages. However, ... Jiang wenming, etc.,al. Analysis of Swan H5N8 Avian Influenza in Holy Lake of Shanxi Province and the Current Virus Lingeage of H5 Subtype Avian Influenza. Sinovet 2017 Vol 34. Abstract
submitted by kickingbird at Jul, 1, 2017 from Sinovet 2017 Vol 34
Abstract:In December 2016，18 white swans died in the scenic area of Holy Lake in Ruicheng county of Shanxiprovince. It was confirmed that the outbreak was caused by the H5N8 subtype highly pathogenic avian ... Smith GE, Sun X, Bai Y, Liu YV, et al.. Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets. Virology 2017;509:90-97. Abstract
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:90-97 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28624679/)
Avian influenza A (H5N1) viruses represent a growing threat for an influenza pandemic. The presence of widespread avian influenza virus infections further emphasizes the need for vaccine strategies for ... Patel H, Kukol A.. Evolutionary conservation of influenza A PB2 sequences reveals potential target sites for small molecule inhibitors. Virology 2017;509:112-120.. Abstract
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:112-120. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28628827/)
The influenza A basic polymerase protein 2 (PB2) functions as part of a heterotrimer to replicate the viral RNA genome. To investigate novel PB2 antiviral target sites, this work identified evolutionary ... Chlanda P. Influenza Hemagglutinin and M2 ion channel priming by trypsin: Killing two birds with one stone. Virology 2017;509:131-132. Abstract
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:131-132 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28644977/)
Influenza A virus membrane fusion and disassembly, prerequisite processes for viral infectivity, depend on acidic pH. In a recent study, Zhirnov et al. reported an important finding-that influenza virions ... Sikora D, Rocheleau L, Brown EG, Pelchat M, et al. Influenza A virus cap-snatches host RNAs based on their abundance early after infection. Virology 2017;509:167-177. Abstract
submitted by kickingbird at Jun, 27, 2017 from Virology 2017;509:167-177 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28646652/)
The influenza A virus RNA polymerase cleaves the 5' ends of host RNAs and uses these RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' host-derived ends of the eight ... Nogales A, Rodriguez L, DeDiego ML, Topham DJ, et. Interplay of PA-X and NS1 proteins in replication and pathogenesis of a temperature-sensitive 2009 pandemic H1N1 influenza A virus. J Virol 2017 Jun 21. Abstract
submitted by kickingbird at Jun, 27, 2017 from J Virol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637750/)
Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics, representing a serious public health concern. It has been described that one mechanism used by some IAV strains to escape the ... Clark AM, Nogales A, Martinez-Sobrido L, Topham DJ. Functional evolution of influenza NS1 protein in currently circulating human 2009 pandemic H1N1 viruses. J Virol 2017 Jun 21. Abstract
submitted by kickingbird at Jun, 27, 2017 from J Virol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637754/)
In 2009, a novel H1N1 influenza virus emerged in humans, causing a global pandemic. It was previously shown that the NS1 protein from this human 2009 pandemic H1N1 (pH1N1) virus was an effective interferon ... Wang Y, Li T, Chen Y, Wei H, et al. Involvement of NK Cells in IL-28B-Mediated Immunity against Influenza Virus Infection. J Immunol 2017 Jun 21. Abstract
submitted by kickingbird at Jun, 27, 2017 from J Immunol 2017 Jun 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28637903/)
IL-28B is a member of the newly discovered type III IFN family and exhibits unique antiviral properties compared with other family members. NK cells play a critical role in defending against viruses; however, ... Ducatez M, et al. Highly pathogenic avian influenza H5N1 clade 2.3.2.1 and clade 2.3.4 viruses do not induce a clade-specific phenotype in mallard ducks. J Gen Virol 2017 Jun 20. Abstract
submitted by kickingbird at Jun, 27, 2017 from J Gen Virol 2017 Jun 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28631606/)
Among the diverse clades of highly pathogenic avian influenza (HPAI) H5N1 viruses of the goose/Guangdong lineage, only a few have been able to spread across continents: clade 2.2 viruses spread from China ... Kesavardhana S, Kuriakose T, Guy CS, Samir P, et a. ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death. J Exp Med 2017 Jun 20. Abstract
submitted by kickingbird at Jun, 27, 2017 from J Exp Med 2017 Jun 20 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28634194/)
Innate sensing of influenza virus infection induces activation of programmed cell death pathways. We have recently identified Z-DNA-binding protein 1 (ZBP1) as an innate sensor of influenza A virus (IAV). ... Moatasim Y, Kandeil A, Mostafa A, Elghaffar SKA, e. Single gene reassortment of highly pathogenic avian influenza A H5N1 in the low pathogenic H9N2 backbone and its impact on pathogenicity and infectivity of novel reassortant viruses. Arch Virol 2017 Jun 15.. Abstract
submitted by kickingbird at Jun, 27, 2017 from Arch Virol 2017 Jun 15. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28620809/)
Avian influenza A H5N1 and H9N2 viruses have been extensively circulating in various avian species and frequently infect mammals, including humans. The synchronous circulation of both viruses in Egypt ... Liu M, Lo EC, Wang G, Chow HF, et al. Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening. Antiviral Res 2017 Jun 16. pii: S0166-3542(16)3058. Abstract
submitted by kickingbird at Jun, 27, 2017 from Antiviral Res 2017 Jun 16. pii: S0166-3542(16)3058 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28629986/)
Influenza A virus is the major cause of epidemics and pandemics worldwide. In this study, virtual screening was used to identify compounds interacting with influenza A polymerase PB2 cap-binding domain ... Paul SS, Mok CK, Mak TM, Ng OW, et al. A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin. Antiviral Res 2017 Jun 17. Abstract
submitted by kickingbird at Jun, 27, 2017 from Antiviral Res 2017 Jun 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28633988/)
The sporadic outbreaks of highly pathogenic H5N1 avian influenza virus have raised public health concerns. Monoclonal antibodies (MAbs) against hemagglutinin (HA) have been increasingly used successfully ... Jing Lu, etc.,al. Molecular evolution, diversity and adaptation of H7N9 influenza A viruses in China. bioRxiv June 25, 2017. Abstract
submitted by kickingbird at Jun, 27, 2017 from bioRxiv June 25, 2017 (via http://biorxiv.org/content/early/2017/06/25/155218)
A novel H7N9 avian influenza virus has caused five human epidemics in China since 2013. The substantial increase in prevalence and the emergence of antigenically divergent or highly pathogenic (HP) H7N9 ... Holly J, Fogelova M, Jakubcova L, Tomcikova K, et. Comparison of infectious influenza A virus quantification methods employing immuno-staining. J Virol Methods 2017 Jun 10. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Virol Methods 2017 Jun 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28610903/)
Infections caused by highly variable influenza A viruses (IAVs) pose perpetual threat to humans as well as to animals. Their surveillance requires reliable methods for their qualitative and quantitative ... Magnen M, Gueugnon F, Guillon A, Baranek T, et al. Kallikrein-related peptidase 5 contributes to H3N2 influenza virus infection in human lungs. J Virol 2017 Jun 14. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Virol 2017 Jun 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28615200/)
The HA (hemagglutinin) of influenza virus must be activated by proteolysis before the virus can become infectious. Previous studies have indicated that HA cleavage is driven by membrane-bound or extracellular ... Mogling R, Richard MJ, Vliet SV, Beek RV, et al. Neuraminidase-mediated haemagglutination of recent human influenza A(H3N2) viruses is determined by arginine 150 flanking the neuraminidase catalytic site. Gen Virol 2017 Jun 13. Abstract
submitted by kickingbird at Jun, 18, 2017 from Gen Virol 2017 Jun 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28612701/)
Over the last decade, an increasing proportion of circulating human influenza A(H3N2) viruses exhibited haemagglutination activity that was sensitive to neuraminidase inhibitors. This change in haemagglutination ... 5147 items, 20/Page, Page[154/258][|<<] [|<] [151] [152] [153] [154] [155] [156] [157] [158] [159] [160] [>|] [>>|] |
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