Wang B, Su Q, Luo J, Li M, Wu Q, Chang H, Du J, Hu. Differences in Highly Pathogenic H5N6 Avian Influenza Viral Pathogenicity and Inflammatory Response in Chickens and Ducks. Front Microbiol. 2021 Jan 29;12:593202. Abstract
submitted by kickingbird at Feb, 16, 2021 from Front Microbiol. 2021 Jan 29;12:593202 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.5932)
Infection with H5N6 highly pathogenic avian influenza virus caused high mortality in chickens, while ducks often appear to be asymptomatic. But, some recent H5Nx subtype viruses could cause high mortality ... Huang J, Wu S, Wu W, Liang Y, Zhuang H, Ye Z, Qu X. The Biological Characteristics of Novel H5N6 Highly Pathogenic Avian Influenza Virus and Its Pathogenesis in Ducks. Front Microbiol. 2021 Jan 26;12:628545. Abstract
submitted by kickingbird at Feb, 16, 2021 from Front Microbiol. 2021 Jan 26;12:628545 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6285)
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) have caused outbreaks in poultry in the world. Some of these viruses acquired internal genes from other subtype avian influenza viruses ... Gierak A, ?mietanka K, de Vos CJ. Quantitative risk assessment of the introduction of low pathogenic avian influenza H5 and H7 strains into Poland via legal import of live poultry. Prev Vet Med. 2021 Jan 28;189:105289. Abstract
submitted by kickingbird at Feb, 16, 2021 from Prev Vet Med. 2021 Jan 28;189:105289 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
Low pathogenic avian influenza (LPAI) caused by H5 and H7 viruses is considered a threatening disease for poultry production due to the possibility of prolonged undetected virus circulation in a poultry ... Hulme KD, Karawita AC, Pegg C, Bunte MJ, Bielefeld. A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants. Elife. 2021 Feb 16;10:e61803. Abstract
submitted by kickingbird at Feb, 16, 2021 from Elife. 2021 Feb 16;10:e61803 (via https://pubmed.ncbi.nlm.nih.gov/33588989/)
Influenza virus has a high mutation rate, such that within one host different viral variants can emerge. Evidence suggests that influenza virus variants are more prevalent in pregnant and/or obese individuals ... Tsuneki-Tokunaga A, Kanai K, Itagaki A, Tsuchie H,. Growth capability of epidemic influenza viruses in Japan since the 2009 H1N1 pandemic. Arch Virol. 2021 Feb 12. Abstract
submitted by kickingbird at Feb, 14, 2021 from Arch Virol. 2021 Feb 12 (via https://link.springer.com/article/10.1007/s00705-021-04976-5)
AbstractThe correlation of viral growth capability (n = 156) with the viral load in nasopharyngeal swabs (n = 76) was assessed. Epidemic influenza A/H1N1, A/H3N2, and B viruses showed a wide range of growth ... Hidekazu Osada, Chon I, Phyu WW, Wagatsuma K, Naga. Development of cycling probe based real-time PCR methodology for influenza A viruses possessing the PA/I38T amino acid substitution associated with reduced baloxavir susceptibility. Antiviral Res. 2021 Feb 9:105036. Abstract
submitted by kickingbird at Feb, 14, 2021 from Antiviral Res. 2021 Feb 9:105036 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
Baloxavir marboxil has been used for influenza treatment since March 2018 in Japan. After baloxavir treatment, the most frequently detected substitution is Ile38Thr in polymerase acidic protein (PA/I38T), ... Ashraf U, Benoit-Pilven C, Navratil V, Ligneau C,. Influenza virus infection induces widespread alterations of host cell splicing. NAR Genom Bioinform. 2020 Nov 21;2(4):lqaa095. Abstract
submitted by kickingbird at Feb, 13, 2021 from NAR Genom Bioinform. 2020 Nov 21;2(4):lqaa095 (via https://academic.oup.com/nargab/article/2/4/lqaa095/5998301)
Influenza A viruses (IAVs) use diverse mechanisms to interfere with cellular gene expression. Although many RNA-seq studies have documented IAV-induced changes in host mRNA abundance, few were designed ... Zeng Y, Xu S, Wei Y, Zhang X, Wang Q, Jia Y, Wang. The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation. PLoS Pathog. 2021 Feb 12;17(2):e1009300. Abstract
submitted by kickingbird at Feb, 13, 2021 from PLoS Pathog. 2021 Feb 12;17(2):e1009300 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A virus (IAV) has evolved various strategies to counteract the innate immune response using different viral proteins. However, the mechanism is not fully elucidated. In this study, we identified ... Almatrrouk S, Saba I, Abozaid S, Al-Qahtani AA, Al. Virus sensing receptors in cellular infectivity of influenza A virus. J Infect Dev Ctries. 2021 Jan 31;15(1):1-8. Abstract
submitted by kickingbird at Feb, 12, 2021 from J Infect Dev Ctries. 2021 Jan 31;15(1):1-8 (via https://www.jidc.org/index.php/journal/article/view/13258)
An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV). The response is classified as early (nonspecific ... Lopez Moreno G, Nirmala J, Goodell C, Culhane M, T. Shedding and transmission of a live attenuated influenza A virus vaccine in pre-weaned pigs under field conditions. PLoS One. 2021 Feb 11;16(2):e0246690. Abstract
submitted by kickingbird at Feb, 12, 2021 from PLoS One. 2021 Feb 11;16(2):e0246690 (via https://pubmed.ncbi.nlm.nih.gov/33571263/)
Influenza A virus (IAV) is one of the most important respiratory viruses affecting pig health and vaccination is the most common strategy to control influenza infections. In this field study we assessed ... Li J, Liang L, Jiang L, Wang Q, Wen X, Zhao Y, Cui. Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission. PLoS Pathog. 2021 Feb 11;17(2):e1009336. Abstract
submitted by kickingbird at Feb, 12, 2021 from PLoS Pathog. 2021 Feb 11;17(2):e1009336 (via https://pubmed.ncbi.nlm.nih.gov/33571308/)
Posttranslational modifications, such as SUMOylation, play specific roles in the life cycle of invading pathogens. However, the effect of SUMOylation on the adaptation, pathogenesis, and transmission of ... Venkatramanan S, Sadilek A, Fadikar A, Barrett CL,. Forecasting influenza activity using machine-learned mobility map. Nat Commun. 2021 Feb 9;12(1):726. Abstract
submitted by kickingbird at Feb, 11, 2021 from Nat Commun. 2021 Feb 9;12(1):726 (via https://www.nature.com/articles/s41467-021-21018-5)
Human mobility is a primary driver of infectious disease spread. However, existing data is limited in availability, coverage, granularity, and timeliness. Data-driven forecasts of disease dynamics are ... Kong H, Burke DF, da Silva Lopes TJ, Takada K, Ima. Plasticity of the Influenza Virus H5 HA Protein. mBio. 2021 Feb 9;12(1):e03324-20. Abstract
submitted by kickingbird at Feb, 11, 2021 from mBio. 2021 Feb 9;12(1):e03324-20 (via https://mbio.asm.org/content/12/1/e03324-20)
Since the emergence of highly pathogenic avian influenza viruses of the H5 subtype, the major viral antigen, hemagglutinin (HA), has undergone constant evolution, resulting in numerous genetic and antigenic ... Zhang X, Li Y, Jin S, Wang T, Sun W, Zhang Y, Li F. H9N2 influenza virus spillover into wild birds from poultry in China bind to human-type receptors and transmit in mammals via respiratory droplets. Transbound Emerg Dis. 2021 Feb 10. Abstract
submitted by kickingbird at Feb, 11, 2021 from Transbound Emerg Dis. 2021 Feb 10 (via https://pubmed.ncbi.nlm.nih.gov/33566453/)
H9N2 influenza virus has been reported worldwide for several decades, and it has evolved into multiple genotypes among domestic poultry. However, the study involving ecology and evolution of low pathogenic ... De Conto F, Conversano F, Razin SV, Belletti S, Ar. Host-cell dependent role of phosphorylated keratin 8 during influenza A/NWS/33 virus (H1N1) infection in mammalian cells. Virus Res. 2021 Feb 5:198333. Abstract
submitted by kickingbird at Feb, 10, 2021 from Virus Res. 2021 Feb 5:198333 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
In this study, we investigated the involvement of keratin 8 during human influenza A/NWS/33 virus (H1N1) infection in semi-permissive rhesus monkey-kidney (LLC-MK2) and permissive human type II alveolar ... Li H, Huang L, Yu Y, Ren X, Li B, Zhang J, Liao M,. Generation of recombinant influenza virus bearing strep tagged PB2 and effective identification of interactional host factors. Vet Microbiol. 2021 Jan 13;254:108985. Abstract
submitted by kickingbird at Feb, 10, 2021 from Vet Microbiol. 2021 Jan 13;254:108985 (via https://www.sciencedirect.com/science/article/pii/S037811352)
The genome of influenza A virus is negative-sense and segmented RNA, which is transcribed and replicated by the viral RNA-dependent RNA polymerase (RdRp) during the virus life cycle. The viral RdRp is ... Crossley BM, Rejmanek D, Baroch J, Stanton JB, You. Nanopore sequencing as a rapid tool for identification and pathotyping of avian influenza A viruses. J Vet Diagn Invest. 2021 Feb 6:1040638720984114. Abstract
submitted by kickingbird at Feb, 10, 2021 from J Vet Diagn Invest. 2021 Feb 6:1040638720984114 (via https://journals.sagepub.com/doi/10.1177/1040638720984114)
We report whole-genome sequencing of influenza A virus (IAV) with 100% diagnostic sensitivity and results available in 500× coverage from each of 16 reference virus isolates evaluated. Subgenomic viral ... Orr-Burks N, Murray J, Todd KV, Bakre A, Tripp RA. GPCR and ion channel genes used by influenza virus for replication. J Virol. 2021 Feb 3:JVI.02410-20. Abstract
submitted by kickingbird at Feb, 5, 2021 from J Virol. 2021 Feb 3:JVI.02410-20 (via https://pubmed.ncbi.nlm.nih.gov/33536179/)
Influenza virus causes epidemics and sporadic pandemics resulting in morbidity, mortality and economic losses. Influenza viruses require host genes to replicate. RNA interference (RNAi) screens can identify ... Mezhenskaya D, Isakova-Sivak I, Kotomina T, Matyus. A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats. Biomedicines. 2021 Feb 1;9(2):133. Abstract
submitted by kickingbird at Feb, 5, 2021 from Biomedicines. 2021 Feb 1;9(2):133 (via https://www.mdpi.com/2227-9059/9/2/133)
Influenza viruses remain a serious public health problem. Vaccination is the most effective way to prevent the disease; however, seasonal influenza vaccines demonstrate low or no effectiveness against ... Youk S, Cho AY, Lee DH, Jeong S, Kim Y, Lee S, Kim. Detection of newly introduced Y280-lineage H9N2 avian influenza viruses in live bird markets in Korea. Transbound Emerg Dis . 2021 Feb 1. Abstract
submitted by kickingbird at Feb, 2, 2021 from Transbound Emerg Dis . 2021 Feb 1 (via https://pubmed.ncbi.nlm.nih.gov/33523603/)
We report the first detection of Y280-lineage H9N2 avian influenza viruses in live bird markets in Korea during July 2020. The viruses were isolated from domestic ducks and chickens traded in three markets ... 6896 items, 20/Page, Page[151/345][|<<] [|<] [151] [152] [153] [154] [155] [156] [157] [158] [159] [160] [>|] [>>|] |
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