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2026-6-11 21:52:11
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Jang H, Ross TM. Hemagglutination Inhibition (HAI) antibody landscapes after vaccination with H7Nx virus like particles. PLoS One. 2021 Mar 18;16(3):e0246613.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from PLoS One. 2021 Mar 18;16(3):e0246613 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: A systemic evaluation of the antigenic differences of the H7 influenza hemagglutinin (HA) proteins, especially for the viruses isolated after 2016, are limited. The purpose of this study was ...

Pu J, Yin Y, Liu J, Wang X, Zhou Y, Wang Z, Sun Y,. Reassortment with dominant chicken H9N2 influenza virus contributed to the fifth H7N9 virus human epidemic. J Virol. 2021 Mar 17:JVI.01578-20.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from J Virol. 2021 Mar 17:JVI.01578-20 (via https://jvi.asm.org/content/early/2021/03/12/JVI.01578-20)
H9N2 Avian influenza virus (AIV) is regarded as a principal donor of viral genes through reassortment to co-circulating influenza viruses that can result in zoonotic reassortants. Whether H9N2 virus can ...

Halldorsson S, Sader K, Turner J, Calder LJ, Rosen. In situ structure and organization of the influenza C virus surface glycoprotein. Nat Commun. 2021 Mar 16;12(1):1694.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from Nat Commun. 2021 Mar 16;12(1):1694 (via https://www.nature.com/articles/s41467-021-21818-9)
The lipid-enveloped influenza C virus contains a single surface glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, that mediates receptor binding, receptor destruction, and membrane fusion ...

Wolf JJ, Xia C, Studstill CJ, Ngo H, Brody SL, And. Influenza A virus NS1 induces degradation of sphingosine 1-phosphate lyase to obstruct the host innate immune response. Virology. 2021 Mar 13;558:67-75.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from Virology. 2021 Mar 13;558:67-75 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The type I interferon (IFN)-mediated innate immune response is one of the central obstacles influenza A virus (IAV) must overcome in order to successfully replicate within the host. We have previously ...

Danzy S, Lowen AC, Steel J. A quantitative approach to assess influenza A virus fitness and transmission in guinea pigs. J Virol. 2021 Mar 17:JVI.02320-20.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from J Virol. 2021 Mar 17:JVI.02320-20 (via https://jvi.asm.org/content/early/2021/03/16/JVI.02320-20)
Efforts to estimate the risk posed by potentially pandemic influenza A viruses (IAV), and to understand the mechanisms governing interspecies transmission, have been hampered by a lack of animal models ...

Zeller MA, Gauger PC, Arendsee ZW, Souza CK, Vince. Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine. mSphere. 2021 Mar 17;6(2):e00920-20.  Abstract  
submitted by kickingbird at Mar, 19, 2021 from mSphere. 2021 Mar 17;6(2):e00920-20 (via https://msphere.asm.org/content/6/2/e00920-20)
The antigenic diversity of influenza A viruses (IAV) circulating in swine challenges the development of effective vaccines, increasing zoonotic threat and pandemic potential. High-throughput sequencing ...

Malausse N, van der Werf S, Naffakh N, Munier S. Influenza B Virus Infection Is Enhanced Upon Heterotypic Co-infection With Influenza A Virus. Front Microbiol. 2021 Feb 25;12:631346.  Abstract  
submitted by kickingbird at Mar, 17, 2021 from Front Microbiol. 2021 Feb 25;12:631346 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6313)
Homotypic co-infections with influenza viruses are described to increase genetic population diversity, to drive viral evolution and to allow genetic complementation. Less is known about heterotypic co-infections ...

Croze M, Kim Y. Inference of population genetic parameters from an irregular time series of seasonal influenza virus sequences. Genetics. 2021 Feb 9;217(2):iyaa039.  Abstract  
submitted by kickingbird at Mar, 17, 2021 from Genetics. 2021 Feb 9;217(2):iyaa039 (via https://academic.oup.com/genetics/article-abstract/217/2/iya)
Basic summary statistics that quantify the population genetic structure of influenza virus are important for understanding and inferring the evolutionary and epidemiological processes. However, the sampling ...

Gaide N, Foret-Lucas C, Figueroa T, Vergne T, Luca. Viral tropism and detection of clade 2.3.4.4b H5N8 highly pathogenic avian influenza viruses in feathers of ducks and geese. Sci Rep. 2021 Mar 15;11(1):5928.  Abstract  
submitted by kickingbird at Mar, 17, 2021 from Sci Rep. 2021 Mar 15;11(1):5928 (via https://www.nature.com/articles/s41598-021-85109-5)
Highly Pathogenic Avian Influenza viruses (HPAIVs) display a tissue pantropism, which implies a possible spread in feathers. HPAIV detection from feathers had been evaluated for H5N1 or H7N1 HPAIVs. It ...

Lee J, Li Y, Li Y, Cino-Ozuna AG, Duff M, Lang Y,. Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge. Vaccine. 2021 Mar 11:S0264-410X(21)00268-1.  Abstract  
submitted by kickingbird at Mar, 16, 2021 from Vaccine. 2021 Mar 11:S0264-410X(21)00268-1 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Swine influenza is an important disease for the swine industry. Currently used whole inactivated virus (WIV) vaccines can induce vaccine-associated enhanced respiratory disease (VAERD) in pigs when the ...

Roosenhoff R, Schutten M, Reed V, Clinch B, van de. Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS). Antiviral Res. 2021 Mar 10:105060.  Abstract  
submitted by kickingbird at Mar, 15, 2021 from Antiviral Res. 2021 Mar 10:105060 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Amino acid substitutions in influenza virus neuraminidase (NA) that cause resistance to neuraminidase inhibitors (NAI) generally result in virus attenuation. However, influenza viruses may acquire secondary ...

Gelenter MD, Mandala VS, Niesen MJM, Sharon DA, Dr. Water orientation and dynamics in the closed and open influenza B virus M2 proton channels. Commun Biol. 2021 Mar 12;4(1):338.  Abstract  
submitted by kickingbird at Mar, 15, 2021 from Commun Biol. 2021 Mar 12;4(1):338 (via https://www.nature.com/articles/s42003-021-01847-2)
The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates proton transport, we have investigated the water ...

Lee J, Cho AY, Ko HH, Ping JF, Ma LJ, Chai CF, Noh. Evaluation of insulated isothermal PCR devices for the detection of avian influenza virus. J Virol Methods. 2021 Mar 9:114126.  Abstract  
submitted by kickingbird at Mar, 15, 2021 from J Virol Methods. 2021 Mar 9:114126 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Highly pathogenic avian influenza viruses (HPAIVs) and low pathogenic avian influenza viruses (LPAIVs) represent important threats to the poultry industry and global human health. Due to the high rates ...

Wu Q, He J, Zhang WY, Zhao KF, Jin J, Yu JL, Chen. The contrasting relationships of relative humidity with influenza A and B in a humid subtropical region. Environ Sci Pollut Res Int. 2021 Mar 12.  Abstract  
submitted by kickingbird at Mar, 13, 2021 from Environ Sci Pollut Res Int. 2021 Mar 12 (via https://link.springer.com/article/10.1007/s11356-021-13107-1)
Influenza is an acute respiratory disease that seriously threatens public health. The occurrence of influenza has been proved to be related to a variety of meteorological factors. However, less attention ...

Peng J, Ran Y, Xie H, Deng L, Li C, Ling C. Sarco/Endoplasmic Reticulum Ca 2+ Transporting ATPase (SERCA) Modulates Autophagic, Inflammatory, and Mitochondrial Responses during Influenza A Virus Infection in Human Lung Cells. J Virol. 2021 Mar 10:JVI.00217-21.  Abstract  
submitted by kickingbird at Mar, 12, 2021 from J Virol. 2021 Mar 10:JVI.00217-21 (via https://jvi.asm.org/content/early/2021/03/09/JVI.00217-21)
Influenza A virus is an important human pathogen causing significant morbidity and mortality. Numerous host factors and cellular responses are dysregulated during influenza A virus infection. This includes ...

Wen S, Wu Z, Zhong S, Li M, Shu Y. Factors influencing the immunogenicity of influenza vaccines. Hum Vaccin Immunother. 2021 Mar 11:1-13.  Abstract  
submitted by kickingbird at Mar, 12, 2021 from Hum Vaccin Immunother. 2021 Mar 11:1-13 (via https://www.tandfonline.com/doi/abs/10.1080/21645515.2021.18)
Annual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect ...

Murphy-Schafer AR, Paust S. Divergent Mast Cell Responses Modulate Antiviral Immunity During Influenza Virus Infection. Front Cell Infect Microbiol. 2021 Feb 19;11:580679.  Abstract  
submitted by kickingbird at Mar, 10, 2021 from Front Cell Infect Microbiol. 2021 Feb 19;11:580679 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.5806)
Influenza A virus (IAV) is a respiratory pathogen that infects millions of people each year. Both seasonal and pandemic strains of IAV are capable of causing severe respiratory disease with a high risk ...

Labadie T, Grassin Q, Batéjat C, Manuguerra JC, Le. Monitoring Influenza Virus Survival Outside the Host Using Real-Time Cell Analysis. J Vis Exp. 2021 Feb 20;(168).  Abstract  
submitted by kickingbird at Mar, 9, 2021 from J Vis Exp. 2021 Feb 20;(168) (via https://www.jove.com/t/61133/monitoring-influenza-virus-surv)
Methods for virus particle quantification represent a critical aspect of many virology studies. Although several reliable techniques exist, they are either time-consuming or unable to detect small variations. ...

Overeem NJ, van der Vries E, Huskens J. A Dynamic, Supramolecular View on the Multivalent Interaction between Influenza Virus and Host Cell. Small. 2021 Mar 7:e2007214.  Abstract  
submitted by kickingbird at Mar, 9, 2021 from Small. 2021 Mar 7:e2007214 (via https://onlinelibrary.wiley.com/doi/10.1002/smll.202007214)
Understanding how influenza viruses traverse the mucus and recognize host cells is critical for evaluating their zoonotic potential, and for prevention and treatment of the disease. The surface of the ...

Na EJ, Kim YS, Lee SY, Kim YJ, Park JS, Oem JK. Genetic Characteristics of Avian Influenza Virus Isolated from Wild Birds in South Korea, 2019-2020. Viruses. 2021 Feb 27;13(3):381.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Viruses. 2021 Feb 27;13(3):381 (via https://www.mdpi.com/1999-4915/13/3/381)
Wild aquatic birds, a natural reservoir of avian influenza viruses (AIVs), transmit AIVs to poultry farms, causing huge economic losses. Therefore, the prevalence and genetic characteristics of AIVs isolated ...

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