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2026-6-11 21:52:06
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Zhang X, Li Y, Jin S, Zhang Y, Sun L, Hu X, Zhao M. PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals. Emerg Microbes Infect. 2021 Apr 12:1-46.  Abstract  
submitted by kickingbird at Apr, 13, 2021 from Emerg Microbes Infect. 2021 Apr 12:1-46 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Influenza H3N8 viruses have been recovered frequently from wild bird species, including Anseriformes (primarily from migratory ducks) and Charadriiformes (primarily from shorebirds). However, little attention ...

Tu YH, Guo Y, Ji S, Shen JL, Fei GH. The Influenza A Virus H3N2 Triggers the Hypersusceptibility of Airway Inflammatory Response via Activating the lncRNA TUG1/miR-145-5p/NF-κB Pathway in COPD. Front Pharmacol. 2021 Feb 22;12:604590.  Abstract  
submitted by kickingbird at Apr, 13, 2021 from Front Pharmacol. 2021 Feb 22;12:604590 (via https://www.frontiersin.org/articles/10.3389/fphar.2021.6045)
Background: Patients with chronic obstructive pulmonary disease (COPD) are more susceptible to influenza A virus (IAV) with more severe symptoms, yet the underlying molecular mechanisms of the hypersusceptibility ...

Chaudhry M, Rashid HB, Thrusfield M, Eisler MC, We. Serosurvey of Avian Influenza Viruses (H5, H7, and H9) and Associated Risk Factors in Backyard Poultry Flocks of Lahore District, Pakistan. Front Vet Sci. 2021 Mar 24;8:631164.  Abstract  
submitted by kickingbird at Apr, 13, 2021 from Front Vet Sci. 2021 Mar 24;8:631164 (via https://www.frontiersin.org/articles/10.3389/fvets.2021.6311)
Rural poultry constitutes 56% of the total poultry population in Pakistan; however, epidemiological information about avian influenza viruses (AIVs) in backyard poultry flocks is lacking. A cross-sectional ...

Deng J, Lu C, Liu C, Oveissi S, Fairlie WD, Lee EF. Influenza A virus infection-induced macroautophagy facilitates MHC class II-restricted endogenous presentation of an immunodominant viral epitope. FEBS J. 2020 Dec 5.  Abstract  
submitted by kickingbird at Apr, 12, 2021 from FEBS J. 2020 Dec 5 (via https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15654)
CD4+ T cells recognize peptides presented by major histocompatibility complex class II molecules (MHC-II). These peptides are generally derived from exogenous antigens. Macroautophagy has been reported ...

Qi Y, Guo W, Liu C, Li S, Chen X. Maternal transfer of antibodies specific for avian influenza viruses in captive whooper swans (Cygnus cygnus). Comp Immunol Microbiol Infect Dis. 2021 Apr 2;76:1.  Abstract  
submitted by kickingbird at Apr, 12, 2021 from Comp Immunol Microbiol Infect Dis. 2021 Apr 2;76:1 (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
The transfer of maternal antibodies to offspring can effectively protect against avian influenza virus (AIV) infection during early life in chickens and can prevent AIV spread by decreasing the overall ...

Sempere Borau M, Stertz S. Entry of influenza A virus into host cells - recent progress and remaining challenges. Curr Opin Virol. 2021 Apr 7;48:23-29.  Abstract  
submitted by kickingbird at Apr, 12, 2021 from Curr Opin Virol. 2021 Apr 7;48:23-29 (via https://www.sciencedirect.com/science/article/pii/S187962572)
Influenza A viruses (IAV) are a major burden for human health and thus the topic of intense research efforts. The entry of IAV into host cells is of particular interest as early infection steps are the ...

Zheng J, Wen L, Yen HL, Liu M, Liu Y, Teng O, Wu W. Phenotypic and functional characteristics of a novel influenza hemagglutinin-specific memory NK cell. J Virol. 2021 Apr 7:JVI.00165-21.  Abstract  
submitted by kickingbird at Apr, 9, 2021 from J Virol. 2021 Apr 7:JVI.00165-21 (via https://jvi.asm.org/content/early/2021/04/02/JVI.00165-21)
Immune memory represents the most efficient defense against invasion and transmission of infectious pathogens. In contrast to memory T and B cells, the roles of innate immunity in recall responses remain ...

Hu Z, Zhao J, Shi L, Hu J, Hu S, Liu X. Identification of the dominant non-neutralizing epitope in the haemagglutinin of H7N9 avian influenza virus. Virus Res. 2021 Apr 2:198409.  Abstract  
submitted by kickingbird at Apr, 6, 2021 from Virus Res. 2021 Apr 2:198409 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
H7N9 avian influenza vaccines induce high levels of non-neutralizing (nonNeu) antibodies against the haemagglutinin (HA). However, the antigenic epitopes underlying this particular antibody response are ...

Tung Yep A, Takeuchi Y, Engelhardt OG, Hufton SE. Broad Reactivity Single Domain Antibodies against Influenza Virus and Their Applications to Vaccine Potency Testing and Immunotherapy. Biomolecules. 2021 Mar 10;11(3):407.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Biomolecules. 2021 Mar 10;11(3):407 (via https://www.mdpi.com/2218-273X/11/3/407)
The antigenic variability of influenza presents many challenges to the development of vaccines and immunotherapeutics. However, it is apparent that there are epitopes on the virus that have evolved to ...

Matsuzaki Y, Sugawara K, Shimotai Y, Kadowaki Y, H. Growth Kinetics of Influenza C Virus Antigenic Mutants That Escaped from Anti-Hemagglutinin Esterase Monoclonal Antibodies and Viral Antigenic Changes Found in Field Isolates. Viruses. 2021 Mar 3;13(3):401.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 3;13(3):401 (via https://www.mdpi.com/1999-4915/13/3/401)
The antigenicity of the hemagglutinin esterase (HE) glycoprotein of influenza C virus is known to be stable; however, information about residues related to antigenic changes has not yet been fully acquired. ...

Torelli A, Gianchecchi E, Monti M, Piu P, Barnesch. Effect of Repeated Freeze-Thaw Cycles on Influenza Virus Antibodies. Vaccines (Basel). 2021 Mar 17;9(3):267.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Vaccines (Basel). 2021 Mar 17;9(3):267 (via https://www.mdpi.com/2076-393X/9/3/267)
Background: Vaccine effectiveness relies on various serological tests, whose aim is the measurement of antibody titer in serum samples collected during clinical trials before and after vaccination. Among ...

Holwerda M, Laloli L, Wider M, Sch?necker L, Becke. Establishment of a Reverse Genetic System from a Bovine Derived Influenza D Virus Isolate. Viruses. 2021 Mar 18;13(3):502.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 18;13(3):502 (via https://www.mdpi.com/1999-4915/13/3/502)
The ruminant-associated influenza D virus (IDV) has a broad host tropism and was shown to have zoonotic potential. To identify and characterize molecular viral determinants influencing the host spectrum ...

Bogatcheva NV, Coleman ME. Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice. Cells. 2021 Mar 24;10(4):720.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Cells. 2021 Mar 24;10(4):720 (via https://www.mdpi.com/2073-4409/10/4/720)
Despite vaccination and antivirals, influenza remains a communicable disease of high burden, with limited therapeutic options available to patients that develop complications. Here, we report the development ...

Yang W, Schountz T, Ma W. Bat Influenza Viruses: Current Status and Perspective. Viruses. 2021 Mar 25;13(4):547.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 25;13(4):547 (via https://www.mdpi.com/1999-4915/13/4/547)
Bats are natural reservoirs for many viruses, including several that are zoonotic. Two unusual H17N10 and H18N11 influenza viruses have been found in New World bats. Although neither of these viruses have ...

Ilyicheva T, Marchenko V, Pyankova O, Moiseeva A,. Antibodies to Highly Pathogenic A/H5Nx (Clade 2.3.4.4) Influenza Viruses in the Sera of Vietnamese Residents. Pathogens. 2021 Mar 25;10(4):394.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Pathogens. 2021 Mar 25;10(4):394 (via https://www.mdpi.com/2076-0817/10/4/394)
To cause a pandemic, an influenza virus has to overcome two main barriers. First, the virus has to be antigenically new to humans. Second, the virus has to be directly transmitted from humans to humans. ...

Nemanichvili N, Berends AJ, Wubbolts RW, Gr?ne A,. Tissue Microarrays to Visualize Influenza D Attachment to Host Receptors in the Respiratory Tract of Farm Animals. Viruses. 2021 Mar 31;13(4):586.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 31;13(4):586 (via https://www.mdpi.com/1999-4915/13/4/586)
The trimeric hemagglutinin-esterase fusion protein (HEF) of influenza D virus (IDV) binds 9-O-acetylated sialic acid receptors, which are expressed in various host species. While cattle are the main reservoir ...

Zhou Y, Pu J, Wu Y. The Role of Lipid Metabolism in Influenza A Virus Infection. Pathogens. 2021 Mar 5;10(3):303.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Pathogens. 2021 Mar 5;10(3):303 (via https://www.mdpi.com/2076-0817/10/3/303)
Influenza A virus (IAV) is an important zoonotic pathogen that can cause disease in animals such as poultry and pigs, and it can cause infection and even death in humans, posing a serious threat to public ...

Ganti K, Bagga A, DaSilva J, Shepard SS, Barnes JR. Avian Influenza A Viruses Reassort and Diversify Differently in Mallards and Mammals. Viruses. 2021 Mar 19;13(3):509.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 19;13(3):509 (via https://www.mdpi.com/1999-4915/13/3/509)
Reassortment among co-infecting influenza A viruses (IAVs) is an important source of viral diversity and can facilitate expansion into novel host species. Indeed, reassortment played a key role in the ...

Park BJ, Park MS, Lee JM, Song YJ. Specific Detection of Influenza A and B Viruses by CRISPR-Cas12a-Based Assay. Biosensors (Basel). 2021 Mar 19;11(3):88.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Biosensors (Basel). 2021 Mar 19;11(3):88 (via https://www.mdpi.com/2079-6374/11/3/88)
A rapid and accurate on-site diagnostic test for pathogens including influenza viruses is critical for preventing the spread of infectious diseases. Two types of influenza virus, A and B cause seasonal ...

Baek YG, Lee YN, Lee DH, Shin JI, Lee JH, Chung DH. Multiple Reassortants of H5N8 Clade 2.3.4.4b Highly Pathogenic Avian Influenza Viruses Detected in South Korea during the Winter of 2020-2021. Viruses. 2021 Mar 16;13(3):490.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 16;13(3):490 (via https://www.mdpi.com/1999-4915/13/3/490)
During October 2020-January 2021, we isolated a total of 67 highly pathogenic avian influenza (HPAI) H5N8 viruses from wild birds and outbreaks in poultry in South Korea. We sequenced the isolates and ...

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