Elgendy EM, Arai Y, Kawashita N, Isobe A, Daidoji. Double mutations in the H9N2 avian influenza virus PB2 gene act cooperatively to increase viral host adaptation and replication for human infections. J Gen Virol. 2021 Jun;102(6). Abstract
submitted by kickingbird at Jun, 2, 2021 from J Gen Virol. 2021 Jun;102(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Avian H9N2 influenza viruses in East Asia are genetically diversified and multiple genotypes (A-W) have been established in poultry. Genotype S strains are currently the most prevalent strains, have caused ... Goldhill DH, Yan A, Frise R, Zhou J, Shelley J, Ga. Favipiravir-resistant influenza A virus shows potential for transmission. PLoS Pathog. 2021 Jun 1;17(6):e1008937. Abstract
submitted by kickingbird at Jun, 2, 2021 from PLoS Pathog. 2021 Jun 1;17(6):e1008937 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage ... Wang Z, Yu J, Sheng Z, Hause BM, Li F, Kaushik RS,. Functional study of a role of N-terminal HA stem region of swine influenza A virus in virus replication. Vet Microbiol. 2021 May 25;258:109132. Abstract
submitted by kickingbird at May, 31, 2021 from Vet Microbiol. 2021 May 25;258:109132 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Swine influenza A virus (SIV) is both a pathogen of economic significance to the swine industry and a potential zoonotic organism that may be transmitted to humans. We described here the detailed characterization ... Chepkwony S, Parys A, Vandoorn E, Stadejek W, Xie. Genetic and antigenic evolution of H1 swine influenza A viruses isolated in Belgium and the Netherlands from 2014 through 2019. Sci Rep. 2021 May 28;11(1):11276. Abstract
submitted by kickingbird at May, 31, 2021 from Sci Rep. 2021 May 28;11(1):11276 (via https://www.nature.com/articles/s41598-021-90512-z)
Surveillance of swine influenza A viruses (swIAV) allows timely detection and identification of new variants with potential zoonotic risks. In this study, we aimed to identify swIAV subtypes that circulated ... Sia ZR, He X, Zhang A, Ang JC, Shao S, Seffouh A,. A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025. Abstract
submitted by kickingbird at May, 31, 2021 from Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025 (via https://www.pnas.org/content/118/22/e2025759118)
Recombinant influenza virus vaccines based on hemagglutinin (HA) hold the potential to accelerate production timelines and improve efficacy relative to traditional egg-based platforms. Here, we assess ... Wen F, Yang J, Guo J, Wang C, Cheng Q, Tang Z, Luo. Genetic characterization of an H5N6 avian influenza virus with multiple origins from a chicken in southern China, October 2019. BMC Vet Res. 2021 May 28;17(1):200. Abstract
submitted by kickingbird at May, 31, 2021 from BMC Vet Res. 2021 May 28;17(1):200 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Highly pathogenic avian influenza viruses (HPAIVs) of H5 subtype pose a great threat to the poultry industry and human health. In recent years, H5N6 subtype has rapidly replaced H5N1 as the ... Yang J, Huang M, Qiao S, Zhang P, Teng Q, Li X, Li. Replication and virulence of chimeric bat influenza viruses in mammalian and avian cells and in mice. Microb Pathog. 2021 May 24:104992. Abstract
submitted by kickingbird at May, 31, 2021 from Microb Pathog. 2021 May 24:104992 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Previous studies have shown that chimeric bat influenza viruses can be generated by reverse genetic system. However, the roles of the surface or internal genes of chimeric bat influenza viruses in viral ... Yan HY, Wang HQ, Zhong M, Wu S, Yang L, Li K, Li Y. PML Suppresses Influenza Virus Replication by Promoting FBXW7 Expression. Virol Sin. 2021 May 27. Abstract
submitted by kickingbird at May, 31, 2021 from Virol Sin. 2021 May 27 (via https://link.springer.com/article/10.1007/s12250-021-00399-3)
Influenza A viruses (IAV) are responsible for seasonal flu epidemics, which can lead to high morbidity and mortality each year. Like other viruses, influenza virus can hijack host cellular machinery for ... Liu H, Gong YN, Shaw-Saliba K, Mehoke T, Evans J,. Differential disease severity and whole-genome sequence analysis for human influenza A/H1N1pdm virus in 2015-2016 influenza season. Virus Evol. 2021 May 18;7(1):veab044. Abstract
submitted by kickingbird at May, 28, 2021 from Virus Evol. 2021 May 18;7(1):veab044 (via https://academic.oup.com/ve/article/7/1/veab044/6261952)
During the 2015-16 winter, the US experienced a relatively mild influenza season compared to Taiwan, which had a higher number of total and severe cases. While H1N1pdm viruses dominated global surveillance ... Senthilkumar D, Kulkarni DD, Venkatesh G, Gupta V,. Widespread Prevalence of Antibodies Against Swine Influenza A (pdm H1N1 09) Virus in Pigs of Eastern Uttar Pradesh, India. Curr Microbiol. 2021 May 26:1–9. Abstract
submitted by kickingbird at May, 28, 2021 from Curr Microbiol. 2021 May 26:1–9 (via https://link.springer.com/article/10.1007/s00284-021-02520-x)
Swine influenza virus (SIV) belongs to family Orthomyxoviridae and can cause acute respiratory infection in pigs. Several pandemic H1N1 human fatal influenza cases were reported in India. Though pigs are ... Liu H, Plancarte M, Ball EE, Weiss CM, Gonzales-Vi. Respiratory tract explant infection dynamics of influenza A virus in California sea lions, northern elephant seals, and rhesus macaques. J Virol. 2021 May 26:JVI0040321. Abstract
submitted by kickingbird at May, 28, 2021 from J Virol. 2021 May 26:JVI0040321 (via https://pubmed.ncbi.nlm.nih.gov/34037419/)
o understand susceptibility of wild California sea lions and Northern elephant seals to influenza A virus (IAV), we developed an ex vivo respiratory explant model and used it to compare infection kinetics ... Sun T, Guo Y, Zhao L, Fan M, Huang N, Tian M, Liu. Evolution of the PB1 gene of human influenza A(H3N2) viruses circulating between 1968 and 2019. Transbound Emerg Dis. 2021 May 25. Abstract
submitted by kickingbird at May, 26, 2021 from Transbound Emerg Dis. 2021 May 25 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14161)
One avian H3N2 influenza virus, providing its PB1 and HA segments, reassorted with one human H2N2 virus and caused a pandemic outbreak in 1968, killing over one million people. After its introduction to ... Bai H, Zhao J, Ma C, Wei H, Li X, Fang Q, Yang P,. Impact of RNA degradation on influenza diagnosis in the surveillance system. Diagn Microbiol Infect Dis. 2021 May 21;100(4):115. Abstract
submitted by kickingbird at May, 26, 2021 from Diagn Microbiol Infect Dis. 2021 May 21;100(4):115 (via https://www.sciencedirect.com/science/article/abs/pii/S07328)
Background: The continuous evolution of influenza viruses is monitored by the World Health Organization Global Influenza Surveillance and Response System. Sample quality is essential for surveillance quality.Methods: ... Huang Y, Lin Z, Wang W, Weiss C, Xie H, Forshee RA. Comparison of hemagglutination inhibition and hemagglutinin pseudovirus neutralization titers in relation to protection against influenza in a mouse model. Lett Appl Microbiol. 2021 May 24. Abstract
submitted by kickingbird at May, 25, 2021 from Lett Appl Microbiol. 2021 May 24 (via https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/lam)
The hemagglutination inhibition (HI) test has long been used as a standard measure of antibody response for inactivated influenza vaccines. However, the HI test has limitations, such as insensitivity when ... Beerens N, Heutink R, Harders F, Roose M, Pritz-Ve. Incursion of Novel Highly Pathogenic Avian Influenza A(H5N8) Virus, the Netherlands, October 2020. Emerg Infect Dis. 2021;27(6):1750-1753. Abstract
submitted by kickingbird at May, 21, 2021 from Emerg Infect Dis. 2021;27(6):1750-1753 (via https://wwwnc.cdc.gov/eid/article/27/6/20-4464_article)
Highly pathogenic avian influenza A(H5N8) virus was detected in mute swans in the Netherlands during October 2020. The virus shares a common ancestor with clade 2.3.4.4b viruses detected in Egypt during ... Li B, Su G, Xiao C, Zhang J, Li H, Sun N, Lao G, Y. The PB2 Co-adaptation of H10N8 Avian Influenza Virus Increases the Pathogenicity to Chickens and Mice. Transbound Emerg Dis. 2021 May 18. Abstract
submitted by kickingbird at May, 20, 2021 from Transbound Emerg Dis. 2021 May 18 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14157)
Avian influenza (AI) is an important zoonotic disease, which can be transmitted across species barriers to other hosts, especially humans, posing a serious threat to the poultry industry and public health. ... Li J, Li R, Zhang Q, Peng P, Wang X, Gu M, Hu Z, J. H7N9 influenza virus-like particle based on BEVS protects chickens from lethal challenge with highly pathogenic H7N9 avian influenza virus. Vet Microbiol. 2021 May 8;258:109106. Abstract
submitted by kickingbird at May, 19, 2021 from Vet Microbiol. 2021 May 8;258:109106 (via https://www.sciencedirect.com/science/article/pii/S037811352)
H7N9 avian influenza virus poses a dual threat to both poultry industry and public health. Therefore, it is highly urgent to develop an effective vaccine to reduce its pandemic potential. Virus-like particles ... Pu J, Zhou JT, Liu P, Yu F, He X, Lu L, Jiang S. Viral Entry Inhibitors Targeting Six-Helical Bundle Core Against Highly Pathogenic Enveloped Viruses with Class I Fusion Proteins. Curr Med Chem. 2021 May 10.. Abstract
submitted by kickingbird at May, 19, 2021 from Curr Med Chem. 2021 May 10. (via https://www.eurekaselect.com/193289/article)
TypeⅠ enveloped viruses bind to cell receptors through surface glycoproteins to initiate infection or undergo receptor-mediated endocytosis. They also initiate membrane fusion in the acidic environment ... Wang B, Li B, Huang H, Yang S, Jian D, Liu J, Yan. Sensitive antibody fluorescence immunosorbent assay (SAFIA) for rapid on-site detection on avian influenza virus H9N2 antibody. Anal Chim Acta. 2021 Jun 15;1164:338524. Abstract
submitted by kickingbird at May, 19, 2021 from Anal Chim Acta. 2021 Jun 15;1164:338524 (via https://www.sciencedirect.com/science/article/abs/pii/S00032)
Avian influenza virus (AIV) is a serious zoonotic disease causing severe damages to both poultry industry and human health. To rapidly detect AIV on-site with high sensitivity and accuracy, we design sensitive ... Zhang P, Ling M, Tan C, Sun Y, Li X, Wang W, Cong. Preparation and evaluation of virus-like particle vaccine against H3N8 subtype equine influenza. Microb Pathog. 2021 May 12:104885. Abstract
submitted by kickingbird at May, 17, 2021 from Microb Pathog. 2021 May 12:104885 (via https://www.sciencedirect.com/science/article/pii/S088240102)
To prevent and control H3N8 subtype equine influenza, we prepared virus-like particles (VLPs) comprising the HA, NA and M1 proteins of H3N8 equine influenza virus (EIV) through the insect cell-baculovirus ... 6896 items, 20/Page, Page[143/345][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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