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2026-6-11 21:52:18
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Zhang C, Guo K, Cui H, Chen L, Zhang C, Wang X, Li. Risk of Environmental Exposure to H7N9 Influenza Virus via Airborne and Surface Routes in a Live Poultry Market in Hebei, China. Front Cell Infect Microbiol. 2021 Jun 7;11:688007.  Abstract  
submitted by kickingbird at Jun, 25, 2021 from Front Cell Infect Microbiol. 2021 Jun 7;11:688007 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.6880)
Environmental transmission of viruses to humans has become an early warning for potential epidemic outbreaks, such as SARS-CoV-2 and influenza virus outbreaks. Recently, an H7N9 virus, A/environment/Hebei/621/2019 ...

Xiao Y, Yang F, Liu F, Cheng L, Yao H, Wu N, Wu H. Development of an antigen-ELISA and a colloidal gold-based immunochromatographic strip based on monoclonal antibodies for detection of avian influenza A(H5) viruses. J Vet Diagn Invest. 2021 Jun 24:10406387211027538.  Abstract  
submitted by kickingbird at Jun, 25, 2021 from J Vet Diagn Invest. 2021 Jun 24:10406387211027538 (via https://journals.sagepub.com/doi/10.1177/10406387211027538)
vian influenza A(H5) viruses (avian IAVs) pose a major threat to the economy and public health. We developed an antigen-ELISA (ag-ELISA) and a colloidal gold-based immunochromatographic strip for the rapid ...

Pedruzzi G, Rouzine IM. An evolution-based high-fidelity method of epistasis measurement: Theory and application to influenza. PLoS Pathog. 2021 Jun 21;17(6):e1009669.  Abstract  
submitted by kickingbird at Jun, 22, 2021 from PLoS Pathog. 2021 Jun 21;17(6):e1009669 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Linkage effects in a multi-locus population strongly influence its evolution. The models based on the traveling wave approach enable us to predict the average speed of evolution and the statistics of phylogeny. ...

Miyauchi K, Adachi Y, Tonouchi K, Yajima T, Harada. Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nat Commun. 2021 Jun 18;12(1):3789.  Abstract  
submitted by kickingbird at Jun, 20, 2021 from Nat Commun. 2021 Jun 18;12(1):3789 (via https://www.nature.com/articles/s41467-021-24090-z)
Influenza viruses are a major public health problem. Vaccines are the best available countermeasure to induce effective immunity against infection with seasonal influenza viruses; however, the breadth ...

Sun H, Liu J, Xiao Y, Duan Y, Yang J, Chen Y, Yu Y. Pathogenicity of novel reassortant Eurasian avian-like H1N1 influenza virus in pigs. Virology. 2021 Jun 6;561:28-35.  Abstract  
submitted by kickingbird at Jun, 19, 2021 from Virology. 2021 Jun 6;561:28-35 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Reassortant Eurasian avian-like (EA) H1N1 virus, possessing 2009 pandemic (pdm/09) and triple-reassortant (TR)-derived internal genes, namely G4 genotype, has replaced the G1 genotype EA H1N1 virus (all ...

Yadav M, Igarashi M, Yamamoto N. Dynamic residue interaction network analysis of the oseltamivir binding site of N1 neuraminidase and its H274Y mutation site conferring drug resistance in influenza A virus. PeerJ. 2021 Jun 2;9:e11552.  Abstract  
submitted by kickingbird at Jun, 19, 2021 from PeerJ. 2021 Jun 2;9:e11552 (via https://peerj.com/articles/11552/)
Background: Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA ...

Zhang J, Li X, Wang X, Ye H, Li B, Chen Y, Chen J,. Genomic evolution, transmission dynamics, and pathogenicity of avian influenza A (H5N8) viruses emerging in China, 2020. Virus Evol. 2021 May 6;7(1):veab046.  Abstract  
submitted by kickingbird at Jun, 19, 2021 from Virus Evol. 2021 May 6;7(1):veab046 (via https://academic.oup.com/ve/article/7/1/veab046/6270935)
Multiple recent outbreaks of highly pathogenic H5N8 viruses originating in aquatic birds frequently occurred in most European countries, Russia, South Korea, and Japan during the winter of 2020-21, and ...

Yu Y, Wu M, Cui X, Xu F, Wen F, Pan L, Li S, Sun H. Pathogenicity and transmissibility of current H3N2 swine influenza virus in Southern China: A zoonotic potential. Transbound Emerg Dis. 2021 Jun 15.  Abstract  
submitted by kickingbird at Jun, 17, 2021 from Transbound Emerg Dis. 2021 Jun 15 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14190)
Swine are considered as "mixing vessels" of influenza A viruses and play an important role in the generation of novel influenza pandemics. In this study, we described that the H3N2 swine influenza (swH3N2) ...

Blumenkrantz DR, Mehoke T, Shaw-Saliba K, Powell H. Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms during the 2014-15 influenza season. Virus Evol. 2021 Jun 4;7(1):veab047.  Abstract  
submitted by kickingbird at Jun, 17, 2021 from Virus Evol. 2021 Jun 4;7(1):veab047 (via https://academic.oup.com/ve/article/7/1/veab047/6272594)
The 2014-15 influenza season saw the emergence of an H3N2 antigenic drift variant that formed the 3C.2a HA clade. Whole viral genomes were sequenced from nasopharyngeal swabs of ninety-four patients with ...

Ghabeshi S, Ebrahimie E, Yavarian J, Salimi V, Sha. Molecular characterization of low pathogenic avian influenza H9N2 virus during co-circulation with newly-emerged highly pathogenic avian influenza H5N8 virus in Iran. Acta Virol. 2021;65(2):200-211.  Abstract  
submitted by kickingbird at Jun, 17, 2021 from Acta Virol. 2021;65(2):200-211 (via https://pubmed.ncbi.nlm.nih.gov/34130471/)
Identification of molecular characteristics of low pathogenic avian influenza (LPAI) H9N2 virus provides insights into the evolution of this subtype due to the modulation of genomic characteristics in ...

Kwon JH, Lee DH, Criado MF, Killmaster L, Ali MZ,. Genetic evolution and transmission dynamics of clade 2.3.2.1a highly pathogenic avian influenza A/H5N1 viruses in Bangladesh. Virus Evol. 2020 Jun 13;6(2):veaa046.  Abstract  
submitted by kickingbird at Jun, 16, 2021 from Virus Evol. 2020 Jun 13;6(2):veaa046 (via https://academic.oup.com/ve/article/6/2/veaa046/5857140)
Asian lineage A/H5N1 highly pathogenic avian influenza viruses (HPAIVs) have been responsible for continuous outbreaks in Bangladesh since 2007. Although clades 2.2.2 and 2.3.4.2 HPAIVs have disappeared ...

Zhao T, Asawa K, Masuda T, Honda A, Kushiro K, Cab. Fluorescent polymeric nanoparticle for ratiometric temperature sensing allows real-time monitoring in influenza virus-infected cells. J Colloid Interface Sci. 2021 Jun 1;601:825-832.  Abstract  
submitted by kickingbird at Jun, 15, 2021 from J Colloid Interface Sci. 2021 Jun 1;601:825-832 (via https://www.sciencedirect.com/science/article/abs/pii/S00219)
Temperature is a key indicator of infection and disease, however, it is difficult to measure at a cellular level. Nanoparticles are applied to measure the cellular temperature, and enhancement of the stability ...

Xing L, Chen Y, Chen B, Bu L, Liu Y, Zeng Z, Guan. Antigenic Drift of the Hemagglutinin from an Influenza A (H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro. Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021 (via https://link.springer.com/article/10.1007/s12250-021-00401-y)
The influenza A (H1N1) pdm09 virus emerged in 2009 and has been continuously circulating in humans for over ten years. Here, we analyzed a clinical influenza A (H1N1) pdm09-infected patient case hospitalized ...

Liu S, Mok BW, Deng S, Liu H, Wang P, Song W, Chen. Mammalian cells use the autophagy process to restrict avian influenza virus replication. Cell Rep. 2021 Jun 8;35(10):109213.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from Cell Rep. 2021 Jun 8;35(10):109213 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(21)005)
Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing avian PB2 infects ...

Criado MF, Moresco KA, Stallknecht DE, Swayne DE. Low-pathogenicity influenza viruses replicate differently in laughing gulls and mallards. Influenza Other Respir Viruses. 2021 Jun 10.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from Influenza Other Respir Viruses. 2021 Jun 10 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12878)
Wild aquatic birds are natural reservoirs of low-pathogenicity avian influenza viruses (LPAIVs). Laughing gulls inoculated with four gull-origin LPAIVs (H7N3, H6N4, H3N8, and H2N3) had a predominate respiratory ...

Barnard KN, Wasik BR, Alford-Lawrence BK, Hayward. Sequence dynamics of three influenza A virus strains grown in different MDCK cell lines, including those expressing different sialic acid receptors. J Evol Biol. 2021 Jun 11.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from J Evol Biol. 2021 Jun 11 (via https://pubmed.ncbi.nlm.nih.gov/34114711/)
Viruses are often cultured in cell lines for research and vaccine development, and those often differ from the natural hosts or tissues. Cell lines can also differ in the presence of virus receptors, such ...

Ziebert F, Kuli? IM. How Influenza´s Spike Motor Works. Phys Rev Lett. 2021 May 28;126(21):218101.  Abstract  
submitted by kickingbird at Jun, 12, 2021 from Phys Rev Lett. 2021 May 28;126(21):218101 (via https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.12)
While often believed to be a passive agent that merely exploits its host's metabolism, the influenza virus has recently been shown to actively move across glycan-coated surfaces. This form of enzymatically ...

Sasaki Y, Yoshino N, Okuwa T, Odagiri T, Satoh T,. A mouse monoclonal antibody against influenza C virus attenuates acetaminophen-induced liver injury in mice. Sci Rep. 2021 Jun 3;11(1):11816.  Abstract  
submitted by kickingbird at Jun, 7, 2021 from Sci Rep. 2021 Jun 3;11(1):11816 (via https://www.nature.com/articles/s41598-021-91251-x)
Molecular mimicry is one of the main processes for producing autoantibodies during infections. Although some autoantibodies are associated with autoimmune diseases, the functions of many autoantibodies ...

Guthmiller JJ, Han J, Li L, Freyn AW, Liu STH, Sto. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med. 2021 Jun 2;13(596):eabg4535.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Sci Transl Med. 2021 Jun 2;13(596):eabg4535 (via https://stm.sciencemag.org/content/13/596/eabg4535)
Broadly neutralizing antibodies are critical for protection against both drifted and shifted influenza viruses. Here, we reveal that first exposure to the 2009 pandemic H1N1 influenza virus recalls memory ...

McCarthy KR, Von Holle TA, Sutherland LL, Oguin TH. Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2026.  Abstract  
submitted by kickingbird at Jun, 4, 2021 from Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2026 (via https://www.pnas.org/content/118/23/e2026752118)
Immune memory of a first infection with influenza virus establishes a lasting imprint. Recall of that memory dominates the response to later infections or vaccinations by antigenically drifted strains. ...

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