Nakano M, Sugita Y, Kodera N, Miyamoto S, Muramoto. Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis. Commun Biol. 2021 Jul 9;4(1):858. Abstract
submitted by kickingbird at Jul, 12, 2021 from Commun Biol. 2021 Jul 9;4(1):858 (via https://www.nature.com/articles/s42003-021-02388-4)
The single-stranded, negative-sense, viral genomic RNA (vRNA) of influenza A virus is encapsidated by viral nucleoproteins (NPs) and an RNA polymerase to form a ribonucleoprotein complex (vRNP) with a ... He D, Gu J, Gu M, Wu H, Li J, Zhan T, Chen Y, Xu N. Genetic and antigenic diversity of H7N9 highly pathogenic avian influenza virus in China from 2017 to 2019. Infect Genet Evol. 2021 Jul 6:104993. Abstract
submitted by kickingbird at Jul, 12, 2021 from Infect Genet Evol. 2021 Jul 6:104993 (via https://www.sciencedirect.com/science/article/abs/pii/S15671)
Avian influenza virus (AIV) H7N9 that emerged in 2013 in eastern China is a novel zoonotic agent mainly circulating in poultry without clinical signs but causing severe disease with high fatality in humans ... Ichimiya T, Okamatsu M, Kinoshita T, Kobayashi D,. Sulfated glycans containing NeuAcα2-3Gal facilitate the propagation of human H1N1 influenza A viruses in eggs. Virology. 2021 Jun 25;562:29-39. Abstract
submitted by kickingbird at Jul, 12, 2021 from Virology. 2021 Jun 25;562:29-39 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
When human influenza viruses are isolated and passaged in chicken embryos, variants with amino acid substitutions around the receptor binding site of hemagglutinin (HA) are selected; however, the mechanisms ... Wang Y, Yuan C, Xu X, Chong TH, Zhang L, Cheung PP. The mechanism of action of T-705 as a unique delayed chain terminator on influenza viral polymerase transcription. Biophys Chem. 2021 Jun 25;277:106652. Abstract
submitted by kickingbird at Jul, 10, 2021 from Biophys Chem. 2021 Jun 25;277:106652 (via https://www.sciencedirect.com/science/article/abs/pii/S03014)
Favipiravir (T-705) has been developed as a potent anti-influenza drug and exhibited a strong inhibition effect against a broad spectrum of RNA viruses. Its active form, ribofuranosyl-triphosphate (T-705-RTP), ... Leyson CM, Youk S, Ferreira HL, Suarez DL, Pantin-. Multiple gene segments are associated with enhanced virulence of clade 2.3.4.4 H5N8 highly pathogenic avian influenza virus in mallards. J Virol. 2021 Jul 7:JVI0095521. Abstract
submitted by kickingbird at Jul, 8, 2021 from J Virol. 2021 Jul 7:JVI0095521 (via https://journals.asm.org/doi/10.1128/JVI.00955-21)
Highly pathogenic avian influenza (HPAI) viruses from the H5Nx Goose/Guangdong/96 lineage continue to cause outbreaks in domestic and wild bird populations. Two distinct genetic groups of H5N8 HPAI viruses, ... Yoo DS, Chun B, Min KD, Lim JS, Moon OK, Lee KN. Elucidating the Local Transmission Dynamics of Highly Pathogenic Avian Influenza H5N6 in the Republic of Korea by Integrating Phylogenetic Information. Pathogens. 2021 Jun 2;10(6):691. Abstract
submitted by kickingbird at Jul, 4, 2021 from Pathogens. 2021 Jun 2;10(6):691 (via https://www.mdpi.com/2076-0817/10/6/691)
Highly pathogenic avian influenza (HPAI) virus is one of the most virulent and infectious pathogens of poultry. As a response to HPAI epidemics, veterinary authorities implement preemptive depopulation ... Liang Y, Krog JS, Ryt-Hansen P, Pedersen AG, Kvisg. Molecular Characterization of Highly Pathogenic Avian Influenza Viruses H5N6 Detected in Denmark in 2018-2019. Viruses. 2021 Jun 2;13(6):1052. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 2;13(6):1052 (via https://www.mdpi.com/1999-4915/13/6/1052)
Beginning in late 2017, highly pathogenic avian influenza (HPAI) H5N6 viruses caused outbreaks in wild birds and poultry in several European countries. H5N6 viruses were detected in 43 wild birds found ... Chrzastek K, Segovia K, Torchetti M, Killian ML, P. Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple G. Viruses. 2021 Jun 18;13(6):1166. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 18;13(6):1166 (via https://www.mdpi.com/1999-4915/13/6/1166)
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States. ... Soh YQS, Malone KD, Eguia RT, Bloom JD. Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir. Viruses. 2021 Jun 22;13(7):1196. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 22;13(7):1196 (via https://www.mdpi.com/1999-4915/13/7/1196)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying ... Xiao Y, Zhang W, Pan M, Bauer DLV, Bi Y, Cao M, Fo. A synergistic effect between 3´ terminal noncoding and adjacent coding regions of influenza A virus HA segment on template preference. J Virol. 2021 Jun 30:JVI0087821. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0087821 (via https://journals.asm.org/doi/10.1128/JVI.00878-21)
The influenza A virus genome is comprised of eight single-stranded negative-sense viral RNA (vRNA) segments. Each of the eight vRNA segments contains segment-specific nonconserved noncoding regions (NCRs) ... Yu J, Huang C, Sheng Z, Wang Z, Li F, Wang D. Identification of One Critical Amino Acid Residue of the Nucleoprotein as a Determinant for in vitro Viral Replication Fitness of Influenza D Virus. J Virol. 2021 Jun 30:JVI0097121. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0097121 (via https://journals.asm.org/doi/10.1128/JVI.00971-21)
The newly identified influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range with broad geographical distribution. Despite the first appearance in U.S. pig herds in 2011, subsequent ... Wang Y, Niu S, Zhang B, Yang C, Zhou Z. The whole genome analysis for the first human infection with H10N3 influenza virus in China. J Infect. 2021 Jun 27:S0163-4453(21)00318-2. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect. 2021 Jun 27:S0163-4453(21)00318-2 (via https://www.journalofinfection.com/article/S0163-4453(21)003)
A strain of H10N3 influenza virus, A/Jiangsu/428/2021/H10N3, was isolated from patient in Jiangsu province, eastern China. Phylogenetic analysis illustrated this human H10N3 virus was a low pathogenic ... Guo F, Roy A, Wang R, Yang J, Zhang Z, Luo W, Shen. Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus. Front Microbiol. 2021 Jun 14;12:655228. Abstract
submitted by kickingbird at Jul, 2, 2021 from Front Microbiol. 2021 Jun 14;12:655228 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6552)
Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations. This virus serves as a useful model for ... Knight ML, Fan H, Bauer DLV, Grimes JM, Fodor E, K. Structure of an H3N2 influenza virus nucleoprotein. Acta Crystallogr F Struct Biol Commun. 2021 Jul 1;. Abstract
submitted by kickingbird at Jul, 2, 2021 from Acta Crystallogr F Struct Biol Commun. 2021 Jul 1; (via https://scripts.iucr.org/cgi-bin/paper?S2053230X2100635X)
Influenza A viruses of the H1N1 and H3N2 subtypes are responsible for seasonal epidemic events. The influenza nucleoprotein (NP) binds to the viral genomic RNA and is essential for its replication. Efforts ... Santos NB, Vaz da Silva ZE, Gomes C, Reis CA, Amor. Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology. PLoS Pathog. 2021 Jul 1;17(7):e1009381. Abstract
submitted by kickingbird at Jul, 2, 2021 from PLoS Pathog. 2021 Jul 1;17(7):e1009381 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to eliminate the pathogen without causing immunopathology. As such, an aggressive initial innate immune ... Giacomelli Cao R, Christian L, Xu Z, Jaramillo L,. Early changes in interferon gene expression and antibody responses following influenza vaccination in pregnant women. J Infect Dis. 2021 Jul 1:jiab345. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect Dis. 2021 Jul 1:jiab345 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Influenza immunization during pregnancy provides protection to the mother and the infant. Studies in adults and children with inactivated influenza vaccine (IIV) have identified changes in ... Zhang Q, Mei X, Zhang C, Li J, Chang N, Aji D, Shi. Novel reassortant 2.3.4.4B H5N6 highly pathogenic avian influenza viruses circulating among wild, domestic birds in Xinjiang, Northwest China. J Vet Sci. 2021 May 11. Abstract
submitted by kickingbird at Jun, 26, 2021 from J Vet Sci. 2021 May 11 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.2021.22.e43)
Background: The H5 avian influenza viruses (AIVs) of clade 2.3.4.4 circulate in wild and domestic birds worldwide. In 2017, nine strains of H5N6 AIVs were isolated from aquatic poultry in Xinjiang, Northwest ... Blaurock C, Breithaupt A, Scheibner D, Bagato O, K. Preferential selection and contribution of non-structural protein 1 (NS1) to the efficient transmission of the panzootic avian influenza H5N8 2.3.4.4 clades A and B viruses in chickens and ducks. J Virol. 2021 Jun 23:JVI0044521. Abstract
submitted by kickingbird at Jun, 26, 2021 from J Virol. 2021 Jun 23:JVI0044521 (via https://journals.asm.org/doi/10.1128/JVI.00445-21)
Highly pathogenic avian influenza viruses H5N8 clade 2.3.4.4 caused outbreaks in poultry at an unprecedented global scale. The virus was spread by wild birds in Asia in two waves: clade-2.3.4.4A in 2014/2015 ... Du L, Pang Y. A novel data-driven methodology for influenza outbreak detection and prediction. Sci Rep. 2021 Jun 24;11(1):13275. Abstract
submitted by kickingbird at Jun, 26, 2021 from Sci Rep. 2021 Jun 24;11(1):13275 (via https://www.nature.com/articles/s41598-021-92484-6)
Influenza is an infectious disease that leads to an estimated 5 million cases of severe illness and 650,000 respiratory deaths worldwide each year. The early detection and prediction of influenza outbreaks ... Vergne T, Gubbins S, Guinat C, Bauzile B, Delpont. Inferring within-flock transmission dynamics of highly pathogenic avian influenza H5N8 virus in France, 2020. Transbound Emerg Dis. 2021 Jun 25. Abstract
submitted by kickingbird at Jun, 26, 2021 from Transbound Emerg Dis. 2021 Jun 25 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14202)
Following the emergence of highly pathogenic avian influenza (H5N8) in France in early December 2020, we used duck mortality data from the index farm to investigate within-flock transmission dynamics. ... 6896 items, 20/Page, Page[141/345][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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