Astill J, etc.,al. Examination of the effects of virus inactivation methods on the induction of antibody- and cell-mediated immune responses against whole inactivated H9N2 avian influenza virus vaccines in chickens. Vaccine. 2018 May 28. pii: S0264-410X(18)30759-X. Abstract
submitted by kickingbird at Jun, 7, 2018 from Vaccine. 2018 May 28. pii: S0264-410X(18)30759-X (via https://www.ncbi.nlm.nih.gov/pubmed/29853199)
Several types of avian influenza virus (AIV) vaccines exist, including live-attenuated, vectored, and whole inactivated virus (WIV) vaccines. Inactivated vaccines offer some advantages compared to other ... Thi Nguyen D, etc.,al. Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles. Emerg Microbes Infect. 2018 May 31;7(1):100. Abstract
submitted by kickingbird at Jun, 7, 2018 from Emerg Microbes Infect. 2018 May 31;7(1):100 (via https://www.ncbi.nlm.nih.gov/pubmed/29855467)
Highly pathogenic avian influenza (HPAI) A(H5N1) viruses pose a significant economic burden to the poultry industry worldwide and have pandemic potential. Poultry vaccination against HPAI A(H5N1) viruses ... Sun X, Pulit-Penaloza JA, Belser JA, Pappas C, et. Pathogenesis and transmission of genetically diverse swine-origin H3N2v influenza A viruses from multiple lineages isolated in the United States, 2011-2016. J Virol 2018 May 30. Abstract
submitted by kickingbird at Jun, 3, 2018 from J Virol 2018 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29848587/)
While several swine-origin influenza A H3N2 variant (H3N2v) viruses isolated from humans prior to 2011 have been previously characterized for their virulence and transmissibility in ferrets, recent genetic ... Yang H, Carney PJ, Chang JC, Guo Z, et al. Structural and Molecular Characterization of the Hemagglutinin from the Fifth Epidemic Wave A(H7N9) Influenza Viruses. J Virol 2018 May 30. Abstract
submitted by kickingbird at Jun, 3, 2018 from J Virol 2018 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29848588/)
The avian influenza A(H7N9) virus continues to cause human infections in China and is a major ongoing public health concern. Five epidemic waves of A(H7N9) infection have occurred since 2013, and the recent ... Wenda Guan, etc.,al. Clinical Correlations of Transcriptional Profile in Patients Infected with Avian Influenza H7N9 Virus. The Journal of Infectious Diseases 28 May 2018. Abstract
submitted by kickingbird at Jun, 2, 2018 from The Journal of Infectious Diseases 28 May 2018 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
BackgroundAvian influenza A (H7N9) viruses emerged in China in 2013 and caused zoonotic disease associated with a case-fatality ratio of over 30%. Transcriptional profiles in peripheral blood reflect host ... Chen L, Lee D, Liu Y, Li W, Swayne DE, Chang J, et. Reassortant Clade 2.3.4.4 of Highly Pathogenic Avian Influenza A(H5N6) Virus, Taiwan, 2017. Emerg Infect Dis. 2018;24(6):1147-1149. Abstract
submitted by kickingbird at Jun, 2, 2018 from Emerg Infect Dis. 2018;24(6):1147-1149 (via https://wwwnc.cdc.gov/eid/article/24/6/17-2071_article)
A highly pathogenic avian influenza A(H5N6) virus of clade 2.3.4.4 was detected in a domestic duck found dead in Taiwan during February 2017. The endemic situation and continued evolution of various reassortant ... Muralidharan A, Gravel C, Duran A, Larocque L, et. Identification of immunodominant CD8 epitope in the stalk domain of influenza B viral hemagglutinin. Biochem Biophys Res Commun 2018 May 21. Abstract
submitted by kickingbird at May, 29, 2018 from Biochem Biophys Res Commun 2018 May 21 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29792863/)
Human infections by type B influenza virus constitute about 25% of all influenza cases. The viral hemagglutinin is comprised of two subunits, HA1 and HA2. While HA1 is constantly evolving in an unpredictable ... Ping He, etc.,al. Novel triple-reassortant influenza viruses in pigs, Guangxi, China. Emerging Microbes & Infectionsvolume 7, Article nu. Abstract
submitted by kickingbird at May, 29, 2018 from Emerging Microbes & Infectionsvolume 7, Article nu (via https://www.nature.com/articles/s41426-018-0088-z)
Considered a “mixing vessel” for influenza viruses, pigs can give rise to new influenza virus reassortants that can threaten humans. During our surveillance of pigs in Guangxi, China from 2013 to 2015, ... Belser JA, Barclay W, Barr I, Fouchier RAM, Matsuy. Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments. Emerg Infect Dis. 2018 Jun;24(6):965-971. Abstract
submitted by kickingbird at May, 23, 2018 from Emerg Infect Dis. 2018 Jun;24(6):965-971 (via https://www.ncbi.nlm.nih.gov/pubmed/29774862)
The ferret transmission model is extensively used to assess the pandemic potential of emerging influenza viruses, yet experimental conditions and reported results vary among laboratories. Such variation ... Suttie A, Yann S, Y P, Tum S, Deng YM, Hul V, Horm. Detection of Low Pathogenicity Influenza A(H7N3) Virus during Duck Mortality Event, Cambodia, 2017. Emerg Infect Dis. 2018 Jun;24(6):1103-1107. Abstract
submitted by kickingbird at May, 23, 2018 from Emerg Infect Dis. 2018 Jun;24(6):1103-1107 (via https://www.ncbi.nlm.nih.gov/pubmed/29774842)
In January 2017, an estimated 3,700 (93%) of 4,000 Khaki Campbell ducks (Anas platyrhynchos domesticus) died in Kampong Thom Province, Cambodia. We detected low pathogenicity avian influenza A(H7N3) virus ... Zhu YC, etc.,al. Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar. Biomed Environ Sci. 2018 Apr;31(4):306-310.. Abstract
submitted by kickingbird at May, 23, 2018 from Biomed Environ Sci. 2018 Apr;31(4):306-310. (via https://www.ncbi.nlm.nih.gov/pubmed/29773094)
To investigate the susceptibility of Chukars to duck avian influenza virus H9N2 and explore their role in interspecies transmission of influenza viruses. Chukars were inoculated with duck avian influenza ... Arafat N, Eladl AH, Marghani BH, Saif MA, El-Shafe. Enhanced infection of avian influenza virus H9N2 with infectious laryngeotracheitis vaccination in chickens. Vet Microbiol. 2018 Jun;219:8-16.. Abstract
submitted by kickingbird at May, 22, 2018 from Vet Microbiol. 2018 Jun;219:8-16. (via https://www.ncbi.nlm.nih.gov/pubmed/29778208)
Avian influenza and infectious laryngeotracheitis viruses are common causes of respiratory diseases in chickens with economical importance worldwide. In this study, we investigated the effect of experimental ... Ikematsu H, etc.,al. In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors in the Japanese 2016-17 season: Comparison with the 2010-11 to 2015-16 seasons. J Infect Chemother. 2018 May 11. Abstract
submitted by kickingbird at May, 22, 2018 from J Infect Chemother. 2018 May 11 (via https://www.ncbi.nlm.nih.gov/pubmed/29759897)
To assess the extent of susceptibility to the four most commonly used neuraminidase inhibitors (NAIs) in the viruses epidemic in the 2016-17 Japanese influenza season, we measured the 50% inhibitory concentration ... Li Y, Sun L, Zheng W, Madina Mahesutihan, et al. Phosphorylation and dephosphorylation of threonine 188 in nucleoprotein is crucial for the replication of influenza A virus. Virology 2018;520:30-38. Abstract
submitted by kickingbird at May, 20, 2018 from Virology 2018;520:30-38 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29775781/)
Nucleoprotein (NP) is a major component of the viral ribonucleoprotein (vRNP) complex that is responsible for viral replication, transcription and packaging of influenza A virus. Phosphorylation of NP ... Venkatesh D, Poen MJ, Bestebroer TM, Scheuer RD, e. Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem. J Virol 2018 May 16.. Abstract
submitted by kickingbird at May, 20, 2018 from J Virol 2018 May 16. (via https://www.ncbi.nlm.nih.gov/m/pubmed/29769347/)
Wild ducks and gulls are the major reservoirs for avian influenza A viruses (AIVs). The mechanisms that drive AIV evolution are complex at sites where various duck and gull species from multiple flyways ... Richards KA, Treanor JJ, Nayak JL, Sant AJ, et al.. Overarching Immunodominance Patterns and Substantial Diversity in Specificity and Functionality in the Circulating Human Influenza A and B CD4 T Cell Repertoire. J Infect Dis 2018 May 12. Abstract
submitted by kickingbird at May, 20, 2018 from J Infect Dis 2018 May 12 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29762692/)
There is limited information on the antigen specificity and functional potential of the influenza-specific CD4 T cell repertoire in humans. Here, ELISPOT assays were used to examine circulating CD4 T cell ... Califano D, Furuya Y, Metzger DW.. Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain. J Immunol 2018 May 14. Abstract
submitted by kickingbird at May, 20, 2018 from J Immunol 2018 May 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29760191/)
Secondary bacterial coinfections following influenza virus pose a serious threat to human health. Therefore, it is of significant clinical relevance to understand the immunological causes of this increased ... Lu C, Yin Y, Meng F, Dun Y, Pei K, Wang C. Discovery of (E)-1-amino-4-phenylbut-3-en-2-ol derivatives as novel neuraminidase inhibitors. Bioorg Med Chem Lett. 2018 May 4. pii: S0960-894X(. Abstract
submitted by kickingbird at May, 17, 2018 from Bioorg Med Chem Lett. 2018 May 4. pii: S0960-894X( (via https://www.ncbi.nlm.nih.gov/pubmed/29748050)
Neuraminidase has been considered as an important target for designing agents against influenza viruses. In a discovery of anti-influenza agents with epigoitrin as the initial lead compound, a series of ... Alymova IV, McCullers JA, Kamal RP, Vogel P. Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses. Sci Rep. 2018 May 10;8(1):7474.. Abstract
submitted by kickingbird at May, 17, 2018 from Sci Rep. 2018 May 10;8(1):7474. (via https://www.ncbi.nlm.nih.gov/pubmed/29749408)
Specific residues of influenza A virus (IAV) PB1-F2 proteins may enhance inflammation or cytotoxicity. In a series of studies, we evaluated the function of these virulence-associated residues in the context ... Perot BP, Boussier J, Yatim N. Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis. 2018 May 10;9(5):539.. Abstract
submitted by kickingbird at May, 17, 2018 from Cell Death Dis. 2018 May 10;9(5):539. (via https://www.ncbi.nlm.nih.gov/pubmed/29748576)
Influenza A virus (IAV) infection perturbs metabolic pathways such as autophagy, a stress-induced catabolic pathway that crosstalks with cellular inflammatory responses. However, the impact of autophagy ... 5178 items, 20/Page, Page[141/259][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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