Zhang J, Cao R, Wang Y, Sun Y, Ji X, Liu P, Liu K,. Influenza virus infection reprograms cholesterol biosynthesis to facilitate virus replication by the TAK1-RORγ axis. PLoS Pathog. 2025 Oct 24;21(10):e1013646. Abstract
submitted by kickingbird at Oct, 25, 2025 from PLoS Pathog. 2025 Oct 24;21(10):e1013646 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Infection and replication of enveloped viruses require host cells to supply substantial amounts of cellular cholesterol for processes such as binding, entry, trafficking, assembly, and budding. However, ... Sung-dae Park, Yeonsu Oh, Dae Sung Yoo. Combating highly pathogenic avian influenza in South Korea: A 15-year retrospective and forward-looking study. Preventive Veterinary Medicine. Abstract
submitted by kickingbird at Oct, 25, 2025 from Preventive Veterinary Medicine (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
Highly Pathogenic Avian Influenza (HPAI), caused by the Orthomyxoviridae family of RNA viruses, poses a serious threat to the global poultry industry, resulting in severe economic losses and raising public ... Tommaso Alfonsi et al. Lightweight multiscale early warning system for influenza A spillovers. Sci. Adv.11,eadz7312(2025). Abstract
submitted by kickingbird at Oct, 25, 2025 from Sci. Adv.11,eadz7312(2025) (via https://www.science.org/doi/10.1126/sciadv.adz7312)
Spillovers of zoonotic Influenza A viruses (IAVs) into farmed animals and humans have the potential to trigger epidemics or even global pandemics. We introduce FluWarning, a highly efficient and elegant ... Taeyong Kwon Kwon, etc.,al. [preprint]Pigs lacking Natural Killer T cells have altered cellular responses to influenza. https://doi.org/10.1101/2025.10.23.684238. Abstract
submitted by kickingbird at Oct, 25, 2025 from https://doi.org/10.1101/2025.10.23.684238 (via https://www.biorxiv.org/content/10.1101/2025.10.23.684238v1)
It is increasingly recognized that innate T cells such as natural killer T (NKT) cells, mucosal associated invariant T (MAIT) cells, and γδ T cells play an important role in shaping adaptive immune responses ... Larsen, B.B., Kimchi, O., Dunkley, O.R.S. et al. RNA structure modulates Cas13 activity and enables mismatch detection. Nat Biotechnol (2025). Abstract
submitted by kickingbird at Oct, 25, 2025 from Nat Biotechnol (2025) (via https://link.springer.com/article/10.1038/s41587-025-02868-6)
Cas13 is activated by the hybridization of a CRISPR RNA to a complementary single-stranded RNA protospacer in a target RNA. While Cas13 is not activated by double-stranded RNA in vitro, it robustly targets ... Zhang C, Jin Y, Cui H, Wang Z, Chen Z, Zhang L, So. Cross-Species Transmission Risks of a Quail-Origin H7N9 Influenza Virus from China Between Avian and Mammalian Hosts. Viruses. 2025; 17(10):1402. Abstract
submitted by kickingbird at Oct, 25, 2025 from Viruses. 2025; 17(10):1402 (via https://www.mdpi.com/1999-4915/17/10/1402)
The H7N9 influenza viruses, which are capable of causing severe respiratory syndrome in humans, were first discovered to infect humans in 2013 and continue to pose a persistent public health threat. Quail ... Leach JR, Oo A, Nogales A, Bosch SI, Martínez-Sobr. LAIV Mutations Selectively Alter Influenza Viral RNA Polymerase Function, Favoring Transcription over Genome Synthesis. Viruses. 2025; 17(11):1412. Abstract
submitted by kickingbird at Oct, 25, 2025 from Viruses. 2025; 17(11):1412 (via https://www.mdpi.com/1999-4915/17/11/1412)
Influenza viruses cause mild to severe lower respiratory infections, sometimes resulting in hospitalization and death. Vaccination remains the primary prophylactic strategy. Live attenuated influenza vaccines ... Bekshin Z, Temirbekova A, Nurbekova Z, Amirkhanova. Epidemiology, Virology, and Control of Highly Pathogenic Avian Influenza in Kazakhstan. Pathogens. 2025; 14(11):1084. Abstract
submitted by kickingbird at Oct, 25, 2025 from Pathogens. 2025; 14(11):1084 (via https://www.mdpi.com/2076-0817/14/11/1084)
This review analyzed the epidemiology and impact of HPAI (H5N1 and H5N8) in migratory birds and poultry in Kazakhstan, with a special focus on outbreaks from 2005 to 2024. A comprehensive bibliographic ... Ihazmade, H., Regragui, Z., Bimouhen, A. et al. Impact of IFITM3 rs12252 and IFNAR2 rs2236757 SNP polymorphisms on influenza virus infection outcomes in Moroccan patients. Mol Biol Rep 53, 2 (2026). Abstract
submitted by kickingbird at Oct, 25, 2025 from Mol Biol Rep 53, 2 (2026) (via https://link.springer.com/article/10.1007/s11033-025-11144-4)
BackgroundSeasonal influenza is a crucial public health concern. Recent populationalstudies, confirmed the involvement of several signaling proteins on the outcome of theinfection. The IFITM3 and IFNAR2 ... Wachsmuth-Melm, M., Peterl, S., O’Riain, A. et al. Visualizing influenza A virus assembly by in situ cryo-electron tomography. Nat Commun 16, 9394 (2025). Abstract
submitted by kickingbird at Oct, 25, 2025 from Nat Commun 16, 9394 (2025) (via https://link.springer.com/article/10.1038/s41467-025-65117-z)
Influenza A virus (IAV) forms pleomorphic particles that package eight ribonucleoprotein complexes (vRNPs), each carrying a distinct RNA genome segment. vRNPs assemble in the nucleus and undergo selective ... Tsuneki-Tokunaga A, Komatsu M, Perdana WY, Nishiya. Epidemic influenza virus strains with high growth capability induce severe inflammatory response in vivo. Virology. 2025 Oct 15;613:110717. Abstract
submitted by kickingbird at Oct, 24, 2025 from Virology. 2025 Oct 15;613:110717 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza epidemics occur worldwide and impose a substantial socioeconomic burden. In our previous studies, epidemic influenza virus strains isolated from seasonal influenza patient specimens exhibited ... Takizawa N, Higashi K, Kawaguchi RK, Gotoh Y, Haya. Concentration-dependent formation of intersegment interactions in the viral inclusions of influenza A virus infected cells. iScience. 2025 Sep 22;28(10):113606. Abstract
submitted by kickingbird at Oct, 24, 2025 from iScience. 2025 Sep 22;28(10):113606 (via https://www.cell.com/iscience/fulltext/S2589-0042(25)01867-X)
The influenza A virus genome consists of eight RNA segments; each incorporated into a virion. It has been proposed that intersegment interactions bundle these segments, and viral inclusions, which contain ... Zhao Y, Han L, Sang H, Yang P, Xiao Y, Hou Y. Genetic Diversity and Evolution of H1N1 Subtype Swine Influenza Virus in China: A Comprehensive Analysis from 1977 to 2020. Evolution. 2025 Oct 22:qpaf213. Abstract
submitted by kickingbird at Oct, 23, 2025 from Evolution. 2025 Oct 22:qpaf213 (via https://academic.oup.com/evolut/advance-article/doi/10.1093/)
Swine influenza virus (SIV) is a highly contagious respiratory pathogen that causes significant economic losses in the swine industry and poses a potential health risk to humans. This study investigated ... Liu D, Leung KY, Zhang R, Lam HY, Fan Y, Xie X, Ch. Efficacy of Oseltamivir Against Seasonal Influenza H1N1 and the Efficacy of a Novel Combination Treatment In Vitro and In Vivo in Mouse Studies. Influenza Other Respir Viruses. 2025 Oct;19(10):e7. Abstract
submitted by kickingbird at Oct, 23, 2025 from Influenza Other Respir Viruses. 2025 Oct;19(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70176)
Background: Influenza surveillance and drug resistance testing have always been central to clinical efforts. Therefore, researching the virus characteristics and antiviral drugs is essential.Method: The ... Singh G, Assato P, Fitz I, Kafle S, Richt JA. Differential Host Responses and Viral Replication of Highly Pathogenic Avian Influenza H5N1 Strains in Diverse Cell Lines with a Raw Milk Supplement. Life. 2025; 15(10):1625. Abstract
submitted by kickingbird at Oct, 22, 2025 from Life. 2025; 15(10):1625 (via https://www.mdpi.com/2075-1729/15/10/1625)
The highly pathogenic avian influenza (HPAI) H5N1 virus poses a growing global health threat, particularly following its unprecedented spillover into dairy cattle and subsequent transmission to more than ... Zhu H, Pu S, He P, Luo J, Gao R. Construction and Research Progress of Animal Models and Mouse Adapted Strains of Seasonal Influenza Virus. Vaccines. 2025; 13(10):1077. Abstract
submitted by kickingbird at Oct, 22, 2025 from Vaccines. 2025; 13(10):1077 (via https://www.mdpi.com/2076-393X/13/10/1077)
Influenza viruses, featured by high variability, pose a persistent public health threat because of an annual seasonal epidemic in the world and irregular global pandemic, requiring animal models to elucidate ... Stettler, M., Hoby, S., Wenker, C. et al. RNA replicon vaccination confers long-lasting protection against H5N1 avian influenza in 23 zoo bird species. Nat Commun 16, 9245 (2025). Abstract
submitted by kickingbird at Oct, 22, 2025 from Nat Commun 16, 9245 (2025) (via https://link.springer.com/article/10.1038/s41467-025-64301-5)
Highly pathogenic avian influenza (HPAI) H5N1 viruses (clade 2.3.4.4b) cause mass mortality in birds and have infected over 50 mammalian species, including humans. Approved avian vaccines remain limited. ... Chang N, Wang H, Aisaiti K, Guo J, Wu T, Zhang C,. Complex Reassortment Dynamics of H9N2 Avian Influenza Viruses in Xinjiang, China: Implications for Zoonotic Spillover. Influenza Other Respir Viruses. 2025;19(10):e70170. Abstract
submitted by kickingbird at Oct, 21, 2025 from Influenza Other Respir Viruses. 2025;19(10):e70170 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70170)
BackgroundH9N2 avian influenza viruses (AIVs) donate their genes to other subtype AIVs, posing significant threats to poultry industries and public health due to their endemicity and zoonotic potential. ... Ailam Lim, etc.,al. [preprint]Unexpected Detection of Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in bovine Semen. https://doi.org/10.1101/2025.10.16.682947. Abstract
submitted by kickingbird at Oct, 19, 2025 from https://doi.org/10.1101/2025.10.16.682947 (via https://www.biorxiv.org/content/10.1101/2025.10.16.682947v1)
Since March 2024, HPAI H5N1 virus has infected dairy cattle in the U.S., prompting concern about novel transmission routes. During an outbreak in California, HPAI H5N1 RNA was detected in an asymptomatic ... Molly C Hetherington-Rauth, etc.,al. [preprint]Targeted tiled amplicon based protocol for sequencing the Hemagglutinin (HA) gene segment of seasonal influenza A and influenza B virus from wastewater at high depth of coverage. https://doi.org/10.1101/2025.10.15.25338105. Abstract
submitted by kickingbird at Oct, 18, 2025 from https://doi.org/10.1101/2025.10.15.25338105 (via https://www.medrxiv.org/content/10.1101/2025.10.15.25338105v)
Wastewater based epidemiology has emerged as a compelling tool to monitor the spread and evolution of pathogens of public health concern. Next generation sequencing (NGS) of pathogens detected in wastewater ... 6604 items, 20/Page, Page[14/331][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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