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2026-6-11 18:51:20
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Del Rosario JMM, da Costa KAS, Asbach B, Ferrara F. Exploiting Pan Influenza A and Pan Influenza B Pseudotype Libraries for Efficient Vaccine Antigen Selection. Vaccines (Basel). 2021 Jul 5;9(7):741.  Abstract  
submitted by kickingbird at Aug, 9, 2021 from Vaccines (Basel). 2021 Jul 5;9(7):741 (via https://www.mdpi.com/2076-393X/9/7/741)
We developed an influenza hemagglutinin (HA) pseudotype library encompassing Influenza A subtypes HA1-18 and Influenza B subtypes (both lineages) to be employed in influenza pseudotype microneutralization ...

Zhang S, Tang X, Wang S, Shi F, Duan C, Bi F, Suo. Establishment of Recombinant Eimeria acervulina Expressing Multi-Copies M2e Derived from Avian Influenza Virus H9N2. Vaccines (Basel). 2021 Jul 16;9(7):791.  Abstract  
submitted by kickingbird at Aug, 9, 2021 from Vaccines (Basel). 2021 Jul 16;9(7):791 (via https://www.mdpi.com/2076-393X/9/7/791)
The potential of Eimeria parasites as live vaccine vectors has been reported with successful genetic manipulation on several species like E. tenella, E. mitis and E. necatrix. Among seven Eimeria species ...

Lee YN, Lee DH, Shin JI, Si YJ, Lee JH, Baek YG, H. Pathogenesis and genetic characteristics of a novel reassortant low pathogenic avian influenza A(H7N6) virus isolated in Cambodia in 2019. Transbound Emerg Dis. 2021 Aug 4..  Abstract  
submitted by kickingbird at Aug, 5, 2021 from Transbound Emerg Dis. 2021 Aug 4. (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14256)
The first human case of zoonotic A(H7N4) avian influenza virus (AIV) infection was reported in early 2018 in China. Two months after this case, novel A(H7N4) viruses phylogenetically related to the Jiangsu ...

Finch J, Zuckerman M, Smith M. Investigating the potential sequence variation in the influenza A matrix genes during the 2018-2019 season in samples from a local population in London. J Virol Methods. 2021 Jul 30:114250..  Abstract  
submitted by kickingbird at Aug, 4, 2021 from J Virol Methods. 2021 Jul 30:114250. (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Recent publications have highlighted the emergence of mutations in the M1 gene of both influenza A H1N1pdm09 and H3N2 subtypes affecting the performance of commercial RT-PCR assays. Respiratory samples ...

Han AX, Felix Garza ZC, Welkers MR, Vigeveno RM, T. Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children. Elife. 2021 Aug 3;10:e68917.  Abstract  
submitted by kickingbird at Aug, 4, 2021 from Elife. 2021 Aug 3;10:e68917 (via https://elifesciences.org/articles/68917)
The evolution of influenza viruses is fundamentally shaped by within-host processes. However, the within-host evolutionary dynamics of influenza viruses remain incompletely understood, in part because ...

Spackman E, Pantin-Jackwood MJ, Sitaras I, Stephen. Identification of Efficacious Vaccines Against Contemporary North American H7 Avian Influenza Viruses. Avian Dis. 2021 Mar;65(1):113-121.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):113-121 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Five vaccines, including four inactivated, whole-virus water-in-oil adjuvanted vaccines and a commercial nonreplicating alphavirus-vectored RNA particle (RP) vaccine were evaluated in chickens for their ...

Wang Y, Chen X, Yuan Y. Antibody Response of an H9 Subtype Avian Influenza Poultry Vaccine on Three Kinds of Wild Birds in Shanghai Zoo. Avian Dis. 2021 Mar;65(1):90-94.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):90-94 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
A semiannual immunization with a commercial inactivated H9 subtype avian influenza virus (AIV) vaccine developed for poultry has been used to prevent and control the avian influenza (AI) infections among ...

Lee DH, Killian ML, Deliberto TJ, Wan XF, Lei L, S. H7N1 Low Pathogenicity Avian Influenza Viruses in Poultry in the United States During 2018. Avian Dis. 2021 Mar;65(1):59-62..  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):59-62. (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Here, we report three detections of H7N1 low pathogenicity avian influenza viruses (LPAIV) from poultry in Missouri (n = 2) and Texas (n = 1) during February and March 2018. Complete genome sequencing ...

Fellahi S, Nassik S, Maaroufi I, Tligui NS, Touzan. Pathogenesis of Avian Influenza Virus Subtype H9N2 in Turkeys and Evaluation of Inactivated Vaccine Efficacy. Avian Dis. 2021 Mar;65(1):46-51.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):46-51 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Avian influenza H9N2 viruses circulate in all types of poultry species, including turkeys, and cause significant losses for the poultry industry in many parts of the word. The aim of this study was to ...

Sangsiriwut K, Noisumdaeng P, Uiprasertkul M, Pras. Full Genomic Sequences of H5N1 Highly Pathogenic Avian Influenza Virus in Human Autopsy Specimens Reveal Genetic Variability and Adaptive Changes for Growth in MDCK Cell Cultures. Biomed Res Int. 2021 Jul 22;2021:3890681.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Biomed Res Int. 2021 Jul 22;2021:3890681 (via https://www.hindawi.com/journals/bmri/2021/3890681/)
The entire H5N1 highly pathogenic avian influenza viral genomes were identified in the frozen autopsy specimens: the trachea, lung, colon, and intestinal feces from a patient who died of the disease in ...

Nudelman I, Kudrin D, Nudelman G, Deshpande R, Har. Comparing Host Module Activation Patterns and Temporal Dynamics in Infection by Influenza H1N1 Viruses. Front Immunol. 2021 Jul 14;12:691758..  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:691758. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6917)
Influenza is a serious global health threat that shows varying pathogenicity among different virus strains. Understanding similarities and differences among activated functional pathways in the host responses ...

Mamontov A, Losev I, Korzhevskii D, Guselnikova V,. Study of Antibody-Dependent Reactions of Mast Cells In Vitro and in a Model of Severe Influenza Infection in Mice. Front Immunol. 2021 Jul 14;12:689436..  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:689436. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6894)
We investigated the reaction of mouse peritoneal mast cells (MCs) in vitro after IgG-containing immune complex introduction using A/H5N1 and A/H1N1pdm09 influenza viruses as antigens. The sera of immune ...

Trifkovic S, Gilbertson B, Fairmaid E, Cobbin J, R. Gene Segment Interactions Can Drive the Emergence of Dominant Yet Suboptimal Gene Constellations During Influenza Virus Reassortment. Front Microbiol. 2021 Jul 14;12:683152.  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Microbiol. 2021 Jul 14;12:683152 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6831)
A segmented genome enables influenza virus to undergo reassortment when two viruses infect the same cell. Although reassortment is involved in the creation of pandemic influenza strains and is routinely ...

Lee K, Pusterla N, Barnum SM, Lee DH, Martínez-Lóp. Genome-informed characterization of antigenic drift in the hemagglutinin gene of equine influenza strains circulating in the United States from 2012 to 2017. Transbound Emerg Dis. 2021 Jul 31.  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Transbound Emerg Dis. 2021 Jul 31 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14262)
Equine influenza virus (EIV) is a major infectious pathogen causing significant respiratory signs in equids worldwide. Voluntary surveillances in the United States (US) recently reported EIV detection ...

Eiden J, Volckaert B, Rudenko O, Aitchison R, Herb. Single Replication M2SR Influenza Vaccine Induced Immune Responses Associated with Protection Against Human Challenge with Highly Drifted H3N2 Influenza Strain. J Infect Dis. 2021 Jul 29:jiab374.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from J Infect Dis. 2021 Jul 29:jiab374 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Background: Current influenza vaccines are strain-specific and demonstrate low vaccine efficacy against H3N2 influenza disease, especially when vaccine is mis-matched to circulating virus. The novel influenza ...

Al Saud AA, Goldsmith AJ, Schulwolf S, Almulhim A,. Ultrasound and Influenza: The Spectrum of Lung and Cardiac Ultrasound Findings in Patients with Suspected Influenza A and B. Ultrasound Med Biol. 2021 Jul 26:S0301-5629(21)002.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Ultrasound Med Biol. 2021 Jul 26:S0301-5629(21)002 (via https://pubmed.ncbi.nlm.nih.gov/34325957/)
In patients with influenza, cardiac and lung ultrasound may help determine the severity of illness and predict clinical outcomes. To determine the ultrasound characteristics of influenza and define the ...

Ngunjiri JM, Taylor KJM, Ji H, Abundo MC, Ghorbani. Influenza A virus infection in turkeys induces respiratory and enteric bacterial dysbiosis correlating with cytokine gene expression. PeerJ. 2021 Jul 22;9:e11806.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from PeerJ. 2021 Jul 22;9:e11806 (via https://peerj.com/articles/11806/)
Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose ...

Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA,. Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in human and murine airway cells. J Virol. 2021 Jul 28:JVI0090621.  Abstract  
submitted by kickingbird at Jul, 29, 2021 from J Virol. 2021 Jul 28:JVI0090621 (via https://journals.asm.org/doi/10.1128/JVI.00906-21)
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs possess a monobasic HA cleavage site cleaved by trypsin-like proteases. Previously, ...

Ryt-Hansen P, Krog JS, Breum S?, Hjulsager CK, Ped. Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses. Elife. 2021 Jul 27;10:e60940.  Abstract  
submitted by kickingbird at Jul, 29, 2021 from Elife. 2021 Jul 27;10:e60940 (via https://elifesciences.org/articles/60940)
Since the influenza pandemic in 2009, there has been an increased focus on swine influenza A virus (swIAV) surveillance. This paper describes the results of the surveillance of swIAV in Danish swine from ...

Plant EP, Ye Z. A Codon-Pair Bias Associated With Network Interactions in Influenza A, B, and C Genomes. Front Genet. 2021 Jul 6;12:699141..  Abstract  
submitted by kickingbird at Jul, 24, 2021 from Front Genet. 2021 Jul 6;12:699141. (via https://www.frontiersin.org/articles/10.3389/fgene.2021.6991)
A new codon-pair bias present in the genomes of different types of influenza virus is described. Codons with fewer network interactions are more frequency paired together than other codon-pairs in influenza ...

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