Kotani O, Suzuki Y, Saito S, Ainai A, Ueno A, Hemm. Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses. Viruses. 2021 Aug 31;13(9):1733. Abstract
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 31;13(9):1733 (via https://www.mdpi.com/1999-4915/13/9/1733)
The stalk domain of influenza virus envelope glycoprotein hemagglutinin (HA) constitutes the axis connecting the head and transmembrane domains, and plays pivotal roles in conformational rearrangements ... Mytle N, Leyrer S, Inglefield JR, Harris AM, Hicke. Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses. Viruses. 2021 Aug 27;13(9):1708. Abstract
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 27;13(9):1708 (via https://www.mdpi.com/1999-4915/13/9/1708)
Influenza hemagglutinin (HA) is considered a major protective antigen of seasonal influenza vaccine but antigenic drift of HA necessitates annual immunizations using new circulating HA versions. Low variation ... Baidya S, Nishimoto Y, Sato S, Shimada Y, Sakurai. Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection. Viruses. 2021 Aug 24;13(9):1674. Abstract
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 24;13(9):1674 (via https://www.mdpi.com/1999-4915/13/9/1674)
The interaction of viral nucleic acid with protein factors is a crucial process for initiating viral polymerase-mediated viral genome replication while activating pattern recognition receptor (PRR)-mediated ... Zhao B, Li H, Cao S, Zhong W, Li B, Jia W, Ning Z. Negative Regulators of Inflammation Response to the Dynamic Expression of Cytokines in DF-1 and MDCK Cells Infected by Avian Influenza Viruses. Inflammation. 2021 Sep 28. Abstract
submitted by kickingbird at Sep, 29, 2021 from Inflammation. 2021 Sep 28 (via https://link.springer.com/article/10.1007%2Fs10753-021-01568)
The H5N1 and H9N2 avian influenza viruses (AIVs) seriously endanger the poultry industry and threaten human health. Characteristic inflammatory responses caused by H5N1 and H9N2 AIVs in birds and mammals ... Elsayed M, Arafa A, Abdelwahab S, Hashish A, Youss. Novel reassortant of H9N2 avian influenza viruses isolated from chickens and quails in Egypt. Vet World. 2021 Aug;14(8):2142-2149. Abstract
submitted by kickingbird at Sep, 28, 2021 from Vet World. 2021 Aug;14(8):2142-2149 (via http://www.veterinaryworld.org/Vol.14/August-2021/21.html)
Background and aim: Poultry infections with H9N2 avian influenza viruses (AIVs) are endemic in Egypt. This study determined the genetic changes in the sequences of H9N2 AIVs isolated from chicken and quails ... Froggatt HM, Burke KN, Chaparian RR, Miranda HA, Z. Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity. PLoS Pathog. 2021 Sep 27;17(9):e1009951. Abstract
submitted by kickingbird at Sep, 28, 2021 from PLoS Pathog. 2021 Sep 27;17(9):e1009951 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are ... Zhang RR, Yang X, Shi CW, Yu LJ, Lian YB, Huang HB. Improved pathogenicity of H9N2 subtype of avian influenza virus induced by mutations occurred after serial adaptations in mice. Microb Pathog. 2021 Sep 22:105204. Abstract
submitted by kickingbird at Sep, 26, 2021 from Microb Pathog. 2021 Sep 22:105204 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
H9N2 subtype, a low pathogenic avian influenza virus, is emerging as a major causative agent circulating poultry workplaces across China and other Asian countries. Increasing case number of interspecies ... Wang T, Wei F, Liu L, Sun Y, Song J, Wang M, Yang. Recombinant HA1-ΔfliC enhances adherence to respiratory epithelial cells and promotes the superiorly protective immune responses against H9N2 influenza virus in chickens. et Microbiol. 2021 Sep 15;262:109238. Abstract
submitted by kickingbird at Sep, 26, 2021 from et Microbiol. 2021 Sep 15;262:109238 (via https://www.sciencedirect.com/science/article/pii/S037811352)
H9N2 subtype avian influenza virus (AIV) is an ongoing threat causing substantial loss to the poultry industry and thus necessitating the development of safe and effective vaccines against AIV. Given that ... Yang F, Xiao Y, Liu F, Yao H, Wu N, Wu H. Molecular Characterization and Antigenic analysis of reassortant H9N2 subtype avian influenza viruses in Eastern China in 2016. Virus Res. 2021 Sep 21:198577.. Abstract
submitted by kickingbird at Sep, 26, 2021 from Virus Res. 2021 Sep 21:198577. (via https://pubmed.ncbi.nlm.nih.gov/34560182/)
H9N2 avian influenza viruses (AIVs) can cause respiratory symptoms and decrease the egg production. Additionally, H9N2 AIVs can provide internal genes for reassortment with other subtypes. During the monitoring ... West J, R?der J, Matrosovich T, Beicht J, Baumann. Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses. PLoS Pathog. 2021 Sep 23;17(9):e1009566.. Abstract
submitted by kickingbird at Sep, 26, 2021 from PLoS Pathog. 2021 Sep 23;17(9):e1009566. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The hemagglutinin (HA) of A/H3N2 pandemic influenza viruses (IAVs) of 1968 differed from its inferred avian precursor by eight amino acid substitutions. To determine their phenotypic effects, we studied ... Song W, Huang X, Guan W, Chen P, Wang P, Zheng M,. Multiple basic amino acids in the cleavage site of H7N9 hemagglutinin contribute to high virulence in mice. J Thorac Dis. 2021 Aug;13(8):4650-4660. Abstract
submitted by kickingbird at Sep, 22, 2021 from J Thorac Dis. 2021 Aug;13(8):4650-4660 (via https://jtd.amegroups.com/article/view/54443/html)
Background: Avian influenza A (H7N9) virus has caused more than 1,500 cases of human infection since its emergence in early 2013. Displaying little or no pathogenicity in poultry, but a 40% case-fatality ... Liu K, Ding P, Pei Y, Gao R, Han W, Zheng H, Ji Z,. Emergence of a novel reassortant avian influenza virus (H10N3) in Eastern China with high pathogenicity and respiratory droplet transmissibility to mammals. Sci China Life Sci. 2021 Sep 17. Abstract
submitted by kickingbird at Sep, 22, 2021 from Sci China Life Sci. 2021 Sep 17 (via https://link.springer.com/article/10.1007%2Fs11427-020-1981-)
Decades have passed since the first discovery of H10-subtype avian influenza virus (AIV) in chickens in 1949, and it has been detected in many species including mammals such as minks, pigs, seals and humans. ... Le TB, Le VP, Lee JE, Kang JA, Trinh TBN, Lee HW,. Reassortant Highly Pathogenic H5N6 Avian Influenza Virus Containing Low Pathogenic Viral Genes in a Local Live Poultry Market, Vietnam. Curr Microbiol. 2021 Sep 21. Abstract
submitted by kickingbird at Sep, 22, 2021 from Curr Microbiol. 2021 Sep 21 (via https://link.springer.com/article/10.1007%2Fs00284-021-02661)
Sites of live poultry trade and marketing are hot spots for avian influenza virus (AIV) transmission. We conducted active surveillance at a local live poultry market (LPM) in northern Vietnamese provinces ... Broszeit F, van Beek RJ, Unione L, Bestebroer TM,. Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Nat Commun. 2021 Sep 14;12(1):5449. Abstract
submitted by kickingbird at Sep, 16, 2021 from Nat Commun. 2021 Sep 14;12(1):5449 (via https://www.nature.com/articles/s41467-021-25713-1)
During circulation in humans and natural selection to escape antibody recognition for decades, A/H3N2 influenza viruses emerged with altered receptor specificities. These viruses lost the ability to agglutinate ... Ferenczi M, Beckmann C, Klaassen M. Rainfall driven and wild-bird mediated avian influenza virus outbreaks in Australian poultry. BMC Vet Res. 2021 Sep 14;17(1):306.. Abstract
submitted by kickingbird at Sep, 16, 2021 from BMC Vet Res. 2021 Sep 14;17(1):306. (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Globally, outbreaks of Avian Influenza Virus (AIV) in poultry continue to burden economies and endanger human, livestock and wildlife health. Wild waterbirds are often identified as possible sources for ... Staller E, Sheppard CM, Baillon L, Frise R, Peacoc. A natural variant in ANP32B impairs influenza virus replication in human cells. J Gen Virol. 2021 Sep;102(9). Abstract
submitted by kickingbird at Sep, 16, 2021 from J Gen Virol. 2021 Sep;102(9) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Viruses require host factors to support their replication, and genetic variation in such factors can affect susceptibility to infectious disease. Influenza virus replication in human cells relies on ANP32 ... Si L, Bai H, Oh CY, Jin L, Prantil-Baun R, Ingber. Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip. Microbiol Spectr. 2021 Sep 15:e0025721. Abstract
submitted by kickingbird at Sep, 16, 2021 from Microbiol Spectr. 2021 Sep 15:e0025721 (via https://journals.asm.org/doi/10.1128/Spectrum.00257-21)
Human-to-human transmission of viruses, such as influenza viruses and coronaviruses, can promote virus evolution and the emergence of new strains with increased potential for creating pandemics. Clinical ... Villalón-Letelier F, Brooks AG, Londrigan SL. MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells. mBio. 2021 Sep 14:e0148421. Abstract
submitted by kickingbird at Sep, 15, 2021 from mBio. 2021 Sep 14:e0148421 (via https://journals.asm.org/doi/10.1128/mBio.01484-21)
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible ... Zhang L, Zheng X, Li J, Wang G, Hu Z, Chen Y, Wang. Long noncoding RNA#45 exerts broad inhibitory effect on influenza a virus replication via its stem ring arms. Virulence. 2021 Dec;12(1):2443-2460. Abstract
submitted by kickingbird at Sep, 15, 2021 from Virulence. 2021 Dec;12(1):2443-2460 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2021.1)
A growing body of evidence suggests the pivotal role of long non-coding RNA (lncRNA) in influenza virus infection. Based on next-generation sequencing, we previously demonstrated that Lnc45 was distinctively ... Ren L, Zhang W, Zhang J, Zhang J, Zhang H, Zhu Y,. Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication. Virol Sin. 2021 Sep 14.. Abstract
submitted by kickingbird at Sep, 15, 2021 from Virol Sin. 2021 Sep 14. (via https://link.springer.com/article/10.1007%2Fs12250-021-00433)
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, ... 6896 items, 20/Page, Page[136/345][|<<] [|<] [131] [132] [133] [134] [135] [136] [137] [138] [139] [140] [>|] [>>|] |
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