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2024-5-14 13:33:39
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Jung-Hoon Kwon, etc.,al. New Reassortant Clade 2.3.4.4b Avian Influenza A(H5N6) Virus in Wild Birds, South Korea, 2017~18. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0461_article)
We isolated new reassortant avian influenza A(H5N6) viruses from feces of wild waterfowl in South Korea during 2017–18. Phylogenetic analysis suggested that reassortment occurred between clade 2.3.4.4b ...

Masato Hatta, etc.,al. Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0403_article)
The recent emergence of highly pathogenic influenza A(H7N9) variants poses a great risk to humans. We show that ferrets vaccinated with low pathogenicity H7N9 virus vaccine do not develop severe symptoms ...

Zhu C, etc.,al. System for the heterologous expression of NS1 protein of H9N2 avian influenza virus in the ciliate Tetrahymena thermophila. J Vet Med Sci. 2018 Sep 11.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Vet Med Sci. 2018 Sep 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30210069)
Tetrahymena is commonly used as an alternative eukaryotic system for efficiently expressing heterologous genes. In this study, we inserted the non-structural (NS) 1 gene of avian influenza virus (AIV) ...

Dunina-Barkovskaya AY, etc.,al. Amphipathic CRAC-Containing Peptides Derived from the Influenza Virus A M1 Protein Modulate Cholesterol-Dependent Activity of Cultured IC-21 Macrophages. Biochemistry (Mosc). 2018 Aug;83(8):982-991.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Biochemistry (Mosc). 2018 Aug;83(8):982-991 (via https://www.ncbi.nlm.nih.gov/pubmed/30208834)
Entry of many viral and bacterial pathogens into host cells depends on cholesterol and/or cholesterol-enriched domains (lipid rafts) in the cell membrane. Earlier, we showed that influenza virus A matrix ...

Marché S, van den Berg T, Lambrecht B. Domestic canaries (Serinus canaria forma domestica) are susceptible to Low Pathogenic Avian Influenza virus infections. Avian Pathol. 2018 Sep 12:0.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Avian Pathol. 2018 Sep 12:0 (via https://www.ncbi.nlm.nih.gov/pubmed/30207746)
Avian influenza viruses have been isolated from many bird species; however, little is known about the susceptibility of pet birds to low pathogenic avian influenza (LPAI) viruses. To address this research ...

Kawaguchi N, Koshimichi H, Ishibashi T, Wajima T. Evaluation of Drug-Drug Interaction Potential between Baloxavir Marboxil and Oseltamivir in Healthy Subjects. Clin Drug Investig. 2018 Sep 10..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Clin Drug Investig. 2018 Sep 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30203386)
BACKGROUND AND OBJECTIVE: Baloxavir marboxil is a prodrug that is metabolized to baloxavir acid, which suppresses viral replication by inhibiting cap-dependent endonuclease with a single oral administration. ...

Krone O, Globig A, Ulrich R, Harder T, etc.,al. White-Tailed Sea Eagle (Haliaeetus albicilla) Die-Off Due to Infection with Highly Pathogenic Avian Influenza Virus, Subtype H5N8, in Germany. Viruses. 2018 Sep 7;10(9).  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Viruses. 2018 Sep 7;10(9) (via https://www.ncbi.nlm.nih.gov/pubmed/30205456)
In contrast to previous incursions of highly pathogenic avian influenza (HPAIV) H5 viruses, H5N8 clade 2.3.4.4b viruses caused numerous cases of lethal infections in white-tailed sea eagles (Haliaeetus ...

Yang W, Yin X, Guan L, Li M, Ma S, Shi J. A live attenuated vaccine prevents replication and transmission of H7N9 highly pathogenic influenza viruses in mammals. Emerg Microbes Infect. 2018 Sep 12;7(1):153.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Emerg Microbes Infect. 2018 Sep 12;7(1):153 (via https://www.ncbi.nlm.nih.gov/pubmed/30206210)
H7N9 influenza viruses emerged in 2013 and have caused severe disease and deaths in humans in China. Some H7N9 viruses circulating in chickens have mutated to highly pathogenic viruses that have caused ...

Capua I, etc.,al. Study of 2009 H1N1 pandemic influenza virus as a possible causative agent of diabetes. J Clin Endocrinol Metab. 2018 Sep 7..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Clin Endocrinol Metab. 2018 Sep 7. (via https://www.ncbi.nlm.nih.gov/pubmed/30203067)
Context: Recent studies have suggested that influenza A virus (IAV) might be involved in the aetiology of diabetes.Objective and methods: To address this question, we tested the ability of H1N1 pandemic ...

Zhang AJX, etc.,al. Prostaglandin E2-mediated impairment of innate immune response to A(H1N1)pdm09 infection in diet-induced obese mice could be restored by paracetamol. J Infect Dis. 2018 Sep 10..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Infect Dis. 2018 Sep 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30202973)
Objective: To investigate why obesity leads to increased severity of influenza infection.Methods: We employed a mouse model with diet-induced obesity (DIO) to study the innate immune responses induced ...

Cowling BJ, etc.,al. Influenza hemagglutination-inhibition antibody titer as a mediator of vaccine-induced protection for influenza B. Clin Infect Dis. 2018 Sep 8..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Clin Infect Dis. 2018 Sep 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30202873)
Background: The hemagglutination inhibition (HAI) assay is an established correlate of protection for the inactivated influenza vaccine, but the proportion of vaccine-induced protection that is mediated ...

Tolba HMN, Abou Elez RMM, Elsohaby I, Ahmed H. Molecular identification of avian influenza virus subtypes H5N1 and H9N2 in birds from farms and live bird markets and in respiratory patients. PeerJ. 2018 Sep 5;6:e5473.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from PeerJ. 2018 Sep 5;6:e5473 (via https://www.ncbi.nlm.nih.gov/pubmed/30202644)
Background: Avian influenza viruses (AIVs) have been endemic in Egypt since 2006, and the co-circulation of high-pathogenic avian influenza H5N1 and low-pathogenic avian influenza H9N2 subtypes in poultry ...

Farrukee R, etc.,al. CHARACTERIZATION OF INFLUENZA B VIRUS VARIANTS WITH REDUCED NEURAMINIDASE INHIBITOR SUSCEPTIBILITY. Antimicrob Agents Chemother. 2018 Sep 10..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Antimicrob Agents Chemother. 2018 Sep 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30201817)
Treatment options for influenza B virus infections are limited to neuraminidase inhibitors (NAIs) which block the neuraminidase (NA) glycoprotein on the virion surface. The development of NAI resistance ...

Khrustalev VV, Khrustaleva TA, Kordyukova LV. Selection and structural analysis of the NY25 peptide - A vaccine candidate from hemagglutinin of swine-origin Influenza H1N1. Microb Pathog. 2018 Sep 7.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Microb Pathog. 2018 Sep 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30201593)
The aim of this study was to construct a vaccine peptide candidate against pandemic Influenza H1N1 hemagglutinin and to test its structure. With the help of bioinformatic algorithms we showed that the ...

Xiao Y, Nolting JM, Sheng ZM, Bristol T, et al. Design and validation of a universal influenza virus enrichment probe set and its utility in deep sequence analysis of primary cloacal swab surveillance samples of wild birds. Virology 2018;524:182-191..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Virology 2018;524:182-191. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30212665/)
Influenza virus infections in humans and animals are major public health concerns. In the current study, a set of universal influenza enrichment probes was developed to increase the sensitivity of sequence-based ...

Yang C, Liu X, Gao Q, Cheng T, et al.. The nucleolar protein LYAR facilitates ribonucleoprotein assembly of influenza A virus. J Virol 2018 Sep 12.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Virol 2018 Sep 12 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30209172/)
Influenza A viral ribonucleoprotein (vRNP) is responsible for transcription and replication of the viral genome in infected cells and depend on host factors for its functions. Identification of the host ...

Keeler SP, Agapov EV, Hinojosa ME, Letvin AN, et a. Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants. J Immunol 2018 Sep 12..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Immunol 2018 Sep 12. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30209189/)
Clinical and experimental observations suggest that chronic lung disease is linked to respiratory viral infection. However, the long-term aspect of this relationship is not yet defined using a virus that ...

Jesper J. Madsen, John M. A. Grime, Jeremy S. Ross. Entropic forces drive clustering and spatial localization of influenza A M2 during viral budding. PNAS September 11, 2018 115 (37) E8595-E8603.  Abstract  
submitted by kickingbird at Sep, 14, 2018 from PNAS September 11, 2018 115 (37) E8595-E8603 (via http://www.pnas.org/content/115/37/E8595)
The influenza A matrix 2 (M2) transmembrane protein facilitates virion release from the infected host cell. In particular, M2 plays a role in the induction of membrane curvature and/or in the scission ...

Levene RE, Gaglia MM. Host Shutoff in Influenza A Virus: Many Means to an End. Viruses. 2018 Sep 5;10(9)..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Viruses. 2018 Sep 5;10(9). (via https://www.ncbi.nlm.nih.gov/pubmed/30189604)
Influenza A virus carries few of its own proteins, but uses them effectively to take control of the infected cells and avoid immune responses. Over the years, host shutoff, the widespread down-regulation ...

Ryan KA, etc.,al. Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung. PLoS One. 2018 Sep 7;13(9):e0202675..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from PLoS One. 2018 Sep 7;13(9):e0202675. (via https://www.ncbi.nlm.nih.gov/pubmed/30192789)
Seasonal influenza virus infections cause yearly epidemics which are the source of a significant public health burden worldwide. The ferret model for human influenza A virus (IAV) is widely used and has ...

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