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2026-6-11 18:51:08
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Chang N, Zhang C, Mei X, Du F, Li J, Zhang L, Du H. Novel reassortment 2.3.4.4b H5N8 highly pathogenic avian influenza viruses circulating in Xinjiang, China. Prev Vet Med. 2021 Dec 22;199:105564.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Prev Vet Med. 2021 Dec 22;199:105564 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
In 2016, H5N8 avian influenza viruses of clade 2.3.4.4b were detected at Qinghai Lake, China. Afterwards, the viruses of this clade rapidly spread to Asia, Europe, and Africa via migratory birds, and caused ...

Sreenivasan CC, Sheng Z, Wang D, Li F. Host Range, Biology, and Species Specificity of Seven-Segmented Influenza Viruses-A Comparative Review on Influenza C and D. Pathogens. 2021 Dec 5;10(12):1583.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Pathogens. 2021 Dec 5;10(12):1583 (via https://www.mdpi.com/2076-0817/10/12/1583)
Other than genome structure, influenza C (ICV), and D (IDV) viruses with seven-segmented genomes are biologically different from the eight-segmented influenza A (IAV), and B (IBV) viruses concerning the ...

Kida Y, Okuya K, Saito T, Yamagishi J, Ohnuma A, H. Structural Requirements in the Hemagglutinin Cleavage Site-Coding RNA Region for the Generation of Highly Pathogenic Avian Influenza Virus. Pathogens. 2021 Dec 9;10(12):1597.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Pathogens. 2021 Dec 9;10(12):1597 (via https://www.mdpi.com/2076-0817/10/12/1597)
Highly pathogenic avian influenza viruses (HPAIVs) with H5 and H7 hemagglutinin (HA) subtypes are derived from their low pathogenic counterparts following the acquisition of multiple basic amino acids ...

Xie L, Xu G, Xin L, Wang Z, Wu R, Wu M, Cheng Y, W. Eurasian Avian-like M1 Plays More Important Role than M2 in Pathogenicity of 2009 Pandemic H1N1 Influenza Virus in Mice. Viruses. 2021 Nov 23;13(12):2335.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Nov 23;13(12):2335 (via https://www.mdpi.com/1999-4915/13/12/2335)
Reassortant variant viruses generated between 2009 H1N1 pandemic influenza virus [A(H1N1)pdm09] and endemic swine influenza viruses posed a potential risk to humans. Surprisingly, genetic analysis showed ...

Suderman M, Moniwa M, Alkie TN, Ojkic D, Broes A,. Comparative Susceptibility of Madin-Darby Canine Kidney (MDCK) Derived Cell Lines for Isolation of Swine Origin Influenza A Viruses from Different Clinical Specimens. Viruses. 2021 Nov 23;13(12):2346.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Nov 23;13(12):2346 (via https://www.mdpi.com/1999-4915/13/12/2346)
Madin-Darby canine kidney (MDCK) cells are commonly used for the isolation of mammalian influenza A viruses. The goal of this study was to compare the sensitivity and suitability of the original MDCK cell ...

El-Shesheny R, Turner JCM, Walker D, Franks J, Sei. Detection of a Novel Reassortant H9N9 Avian Influenza Virus in Free-Range Ducks in Bangladesh. Viruses. 2021 Nov 24;13(12):2357.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Nov 24;13(12):2357 (via https://www.mdpi.com/1999-4915/13/12/2357)
Wild aquatic birds are the primary natural reservoir for influenza A viruses (IAVs). In this study, an A(H9N9) influenza A virus (A/duck/Bangladesh/44493/2020) was identified via routine surveillance in ...

Kalonda A, Phonera M, Saasa N, Kajihara M, Sutclif. Influenza A and D Viruses in Non-Human Mammalian Hosts in Africa: A Systematic Review and Meta-Analysis. Viruses. 2021 Dec 2;13(12):2411.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Dec 2;13(12):2411 (via https://www.mdpi.com/1999-4915/13/12/2411)
We conducted a systematic review and meta-analysis to investigate the prevalence and current knowledge of influenza A virus (IAV) and influenza D virus (IDV) in non-human mammalian hosts in Africa. PubMed, ...

Bonney PJ, Malladi S, Ssematimba A, St Charles KM,. Simulated Flock-Level Shedding Characteristics of Turkeys in Ten Thousand Bird Houses Infected with H7 Low Pathogenicity Avian Influenza Virus Strains. Viruses. 2021 Dec 14;13(12):2509.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Dec 14;13(12):2509 (via https://www.mdpi.com/1999-4915/13/12/2509)
Understanding the amount of virus shed at the flock level by birds infected with low pathogenicity avian influenza virus (LPAIV) over time can help inform the type and timing of activities performed in ...

He D, Gu M, Wang X, Wang X, Li G, Yan Y, Gu J, Zha. Spatiotemporal Associations and Molecular Evolution of Highly Pathogenic Avian Influenza A H7N9 Virus in China from 2017 to 2021. Viruses. 2021 Dec 15;13(12):2524.  Abstract  
submitted by kickingbird at Dec, 29, 2021 from Viruses. 2021 Dec 15;13(12):2524 (via https://www.mdpi.com/1999-4915/13/12/2524)
Highly pathogenic (HP) H7N9 avian influenza virus (AIV) emerged in China in 2016. HP H7N9 AIV caused at least 33 human infections and has been circulating in poultry farms continuously since wave 5. The ...

Li Y, Li P, Xi J, Yang J, Wu H, Zhang Y, Cao M, Ch. Wild bird-origin H3N8 avian influenza virus exhibit well adaptation in mammalian host. J Infect. 2021 Dec 22:S0163-4453(21)00637-X.  Abstract  
submitted by kickingbird at Dec, 28, 2021 from J Infect. 2021 Dec 22:S0163-4453(21)00637-X (via https://www.journalofinfection.com/article/S0163-4453(21)006)
?A novel reassortant avian influenza A(H3N8) virus was isolated from wild birds?Several putative mammalian adaptive mutation was occurred in this H3N8 virus?This H3N8 virus can bind to both avian-type ...

Wang F, Wan Z, Wang Y, Wu J, Fu H, Gao W, Shao H,. Identification of Hemagglutinin Mutations Caused by Neuraminidase Antibody Pressure. Microbiol Spectr. 2021 Dec 22;9(3):e0143921.  Abstract  
submitted by kickingbird at Dec, 25, 2021 from Microbiol Spectr. 2021 Dec 22;9(3):e0143921 (via https://journals.asm.org/doi/10.1128/spectrum.01439-21)
The balance in the functions of hemagglutinin (HA) and neuraminidase (NA) plays an important role in influenza virus genesis. However, whether and how N2 neuraminidase-specific antibodies may affect the ...

Huang Y, Skarlupka AL, Jang H, Blas-Machado U, Hol. SARS-CoV-2 and Influenza A virus Co-infections in Ferrets. J Virol. 2021 Dec 22:JVI0179121.  Abstract  
submitted by kickingbird at Dec, 25, 2021 from J Virol. 2021 Dec 22:JVI0179121 (via https://journals.asm.org/doi/10.1128/JVI.01791-21)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and seasonal influenza viruses are co-circulating in the human population. However, only a few cases of viral co-infection with these two viruses ...

Nilsson-Payant BE, tenOever BR, Te Velthuis AJW. The host factor ANP32A is required for influenza A virus vRNA and cRNA synthesis. J Virol. 2021 Dec 22:jvi0209221.  Abstract  
submitted by kickingbird at Dec, 25, 2021 from J Virol. 2021 Dec 22:jvi0209221 (via https://journals.asm.org/doi/10.1128/jvi.02092-21)
Influenza A viruses are negative-sense RNA viruses that rely on their own viral replication machinery to replicate and transcribe their segmented single-stranded RNA genome. The viral ribonucleoprotein ...

Li-Juan L, Kang S, Zhi-Juan L, Dan L, Feng X, Peng. Klebsiella pneumoniae infection following H9N2 influenza A virus infection contributes to the development of pneumonia in mice. Vet Microbiol. 2021 Dec 7;264:109303.  Abstract  
submitted by kickingbird at Dec, 21, 2021 from Vet Microbiol. 2021 Dec 7;264:109303 (via https://www.sciencedirect.com/science/article/pii/S037811352)
In this study, whether H9N2 influenza A virus (IAV) infection contributed to secondary Klebsiella pneumoniae infection was investigated. From post-infection onwards, clinical symptoms were monitored, examined ...

Gunther RC, Bharathi V, Miles SD, Tumey LR, Schmed. Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice. Front Immunol. 2021 Dec 1;12:791017.  Abstract  
submitted by kickingbird at Dec, 21, 2021 from Front Immunol. 2021 Dec 1;12:791017 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.7910)
Background: Innate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent ...

Bauzile B, Sicard G, Guinat C, Andraud M, Rose N,. Unravelling direct and indirect contact patterns between duck farms in France and their association with the 2016-2017 epidemic of Highly Pathogenic Avian Influenza (H5N8). Prev Vet Med. 2021 Nov 23;198:105548.  Abstract  
submitted by kickingbird at Dec, 20, 2021 from Prev Vet Med. 2021 Nov 23;198:105548 (via https://www.sciencedirect.com/science/article/pii/S016758772)
Live animal movements generate direct contacts (via the exchange of live animals) and indirect contacts (via the transit of transport vehicles) between farms, which can contribute to the spread of pathogens. ...

Yoo DS, Chun BC, Kim Y, Lee KN, Moon OK. Dynamics of inter-farm transmission of highly pathogenic avian influenza H5N6 integrating vehicle movements and phylogenetic information. Sci Rep. 2021 Dec 17;11(1):24163.  Abstract  
submitted by kickingbird at Dec, 20, 2021 from Sci Rep. 2021 Dec 17;11(1):24163 (via https://www.nature.com/articles/s41598-021-03284-x)
Highly pathogenic avian influenza (HPAI) in poultry holdings commonly spreads through animal trade, and poultry production and health-associated vehicle (PPHaV) movement. To effectively control the spread ...

Fujita D, Dapat C, Kagning Tsinda E, Saito M, Okam. Near-Complete Genome Sequencing of Influenza C Virus in the Philippines between 2014 and 2019. Microbiol Resour Announc. 2021 Dec 9;10(49):e00900.  Abstract  
submitted by kickingbird at Dec, 10, 2021 from Microbiol Resour Announc. 2021 Dec 9;10(49):e00900 (via https://journals.asm.org/doi/10.1128/MRA.00900-21)
We report 19 nearly complete genome sequences of influenza C virus isolated from clinical samples recovered from children in the Philippines between 2014 and 2019.

Li F, Liu J, Yang J, Sun H, Jiang Z, Wang C, Zhang. H9N2 virus-derived M1 protein promotes H5N6 virus release in mammalian cells: Mechanism of avian influenza virus inter-species infection in humans. PLoS Pathog. 2021 Dec 3;17(12):e1010098.  Abstract  
submitted by kickingbird at Dec, 8, 2021 from PLoS Pathog. 2021 Dec 3;17(12):e1010098 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
H5N6 highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4 not only exhibits unprecedented intercontinental spread in poultry, but can also cause serious infection in humans, posing a public health ...

Song Y, Huang H, Hu Y, Zhang J, Li F, Yin X, Shi J. A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLoS Pathog. 2021 Dec 6;17(12):e1010141.  Abstract  
submitted by kickingbird at Dec, 8, 2021 from PLoS Pathog. 2021 Dec 6;17(12):e1010141 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza virus infection is dependent on host cellular factors, and identification of these factors and their underlying mechanisms can provide important information for the development of strategies ...

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