Hou Z, Wang H, Zhang B, Liu R, Zhang Y, Yang Y, Wu. Aerosol Inhalation of a Recombinant H7N9 Hemagglutinin Antigen Elicits Systemic and Mucosal Immune Responses in Mice. Viruses. 2026 May 21;18(5):579. Abstract
submitted by kickingbird at May, 28, 2026 from Viruses. 2026 May 21;18(5):579 (via https://www.mdpi.com/1999-4915/18/5/579)
Highly pathogenic avian influenza A (H7N9) remains a threat to poultry health and poses a zoonotic risk, highlighting the need for vaccine antigens capable of inducing both systemic and mucosal immunity. ... Zhang Y, Qin C, Zhuang Y, Chen L, Zeng X, Jiang L,. USP17L13 Enhances Influenza a Virus Replication by Mediating the Degradation of RIG-I and MDA5. Viruses. 2026 May 20;18(5):575. Abstract
submitted by kickingbird at May, 28, 2026 from Viruses. 2026 May 20;18(5):575 (via https://www.mdpi.com/1999-4915/18/5/575)
The innate immune system, particularly the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway, is a major early defense barrier against influenza A virus infection. However, excessive ... Loes AN, Tarabi RAL, Li SH, Atkinson RK, Huddlesto. Strain-specific differences in the response to egg-derived versus recombinant protein influenza vaccines. J Virol. 2026 May 27:e0031726. Abstract
submitted by kickingbird at May, 28, 2026 from J Virol. 2026 May 27:e0031726 (via https://journals.asm.org/doi/10.1128/jvi.00317-26)
The 2023/2024 influenza vaccine included an updated H1N1 component designed to better match a new clade of H1N1 that had multiple mutations in antigenic epitopes of hemagglutinin. Despite this update, ... European Food Safety Authority (EFSA), Miguel Melo. Deriving species-specific relative weights for wild birds in a spatio-temporal risk model of HPAI in Europe. EFSA. Abstract
submitted by kickingbird at May, 27, 2026 from EFSA (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/sp.efsa.202)
This report describes the derivation of species-specific relative weights for 25 wild bird species evaluated for inclusion in the Bird Flu Radar, a spatio-temporal risk assessment tool developed by the ... Hannah L Wallace, etc.,al. [preprint]Detection of Anti-H5 Antibodies in People with Exposure to Wild Birds in Northern Canada. https://doi.org/10.64898/2026.05.24.26353994. Abstract
submitted by kickingbird at May, 27, 2026 from https://doi.org/10.64898/2026.05.24.26353994 (via https://www.medrxiv.org/content/10.64898/2026.05.24.26353994)
Using a commercially available H5 serology assay, we identified a 7.4% (n=5/68) anti-H5 seroreactivity rate among hunters in Northern Canada. All participants reported close contact with wild birds. Ross A. Edwards, etc.,al. [preprint]The Q226H Mutation in Avian H5N1 Hemagglutinin Mediates a Path towards Structural Adaptation in Humans. https://doi.org/10.64898/2026.05.21.726965. Abstract
submitted by kickingbird at May, 27, 2026 from https://doi.org/10.64898/2026.05.21.726965 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726965v1)
The global outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) among birds and the spillover to mammals increases the risk for humans. A recent case in British Columbia with a clade 2.3.4.4b H5 ... Rang Wang, etc.,al. Genetic determinants of cell- and egg-preferred replication in H3N2 canine influenza virus. Veterinary Microbiology. Abstract
submitted by kickingbird at May, 27, 2026 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The H3N2 canine influenza virus (CIV), which originated from avian influenza viruses and has circulated in dogs for over two decades, remains poorly understood in terms of its host adaptation mechanisms ... Heidi Liu, etc.,al. Strain-specific responses of avian influenza virus to disruption of solute carrier family 35 member A1 (SLC35A1) in chicken cells. Poultry Science. Abstract
submitted by kickingbird at May, 27, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) poses a persistent threat to poultry health and food security, with conventional control measures offering limited protection. A promising alternative is the use of gene editing ... Gomaa MR, Yazbek J, et al. Spill-Over of Avian and Human Influenza a Viruses to Swine in Egypt and Lebanon. Zoonotic Diseases. 2026; 6(2):21. Abstract
submitted by kickingbird at May, 26, 2026 from Zoonotic Diseases. 2026; 6(2):21 (via https://www.mdpi.com/2813-0227/6/2/21)
Influenza A viruses circulate between birds, humans, and pigs, creating opportunities for the emergence of new strains with potential public health impact. In avian influenza (AI)-endemic countries such ... Zhang Y, Bai X, Nie C, et al. Clade 2.3.4.4b H5N1 HPAIV from Migratory Birds in Beidaihe Wetland, North China. Viruses. 2026; 18(6):595. Abstract
submitted by kickingbird at May, 26, 2026 from Viruses. 2026; 18(6):595 (via https://www.mdpi.com/1999-4915/18/6/595)
During 2022–2024, a highly pathogenic avian influenza virus (HPAIV) H5N1 strain, designated A/Seagull/Hebei/qhd6/2024 (H5N1), was isolated from migratory birds in Beidaihe National Wetland Park, North ... Vanstreels RET, Serafini PP, Giacinti J, Younger J. A public database to monitor the spread and impacts of high pathogenicity avian influenza viruses on albatrosses and petrels. Biodivers Data J. 2026 May 15;14:e186836. Abstract
submitted by kickingbird at May, 26, 2026 from Biodivers Data J. 2026 May 15;14:e186836 (via https://bdj.pensoft.net/article/186836/)
Background: High pathogenicity avian influenza (HPAI) viruses have rapidly emerged as a major global threat to wildlife, with severe consequences for seabird populations. Albatrosses and petrels (order ... Kieran Dee, etc.,al. [preprint]Understanding the emergence of the influenza A/H3N2 K subclade in its historical and evolutionary context. https://doi.org/10.64898/2026.05.21.726823. Abstract
submitted by kickingbird at May, 25, 2026 from https://doi.org/10.64898/2026.05.21.726823 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726823v1)
The emergence in 2025/26 of the influenza A/H3N2 K substrain (H3N2/K) was the cause of significant public health concern. This genetically divergent virus was assessed to have a strongly decreased reactivity ... Taehee Chang, Sangyi Lee, Jin Il Kim, Kyung-Duk Mi. [preprint]Spatiotemporal Dynamics of Highly Pathogenic Avian Influenza H5 Virus Introductions and Regional Spread in the Republic of Korea. https://doi.org/10.64898/2026.05.21.726857. Abstract
submitted by kickingbird at May, 25, 2026 from https://doi.org/10.64898/2026.05.21.726857 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726857v1)
Highly pathogenic avian influenza (HPAI) viruses from clade 2.3.4.4 have caused recurrent outbreaks in poultry since 2014. In the Republic of Korea, clade 2.3.4.4b viruses have driven five epidemic waves, ... Bojarzyn, C.R., Bie?, N., Behrens, M. et al. The activation of the metabolic oxaloacetate-pyruvate axis restores influenza A virus replication during impaired glycolysis. Virol J (2026). Abstract
submitted by kickingbird at May, 25, 2026 from Virol J (2026) (via https://link.springer.com/article/10.1186/s12985-026-03201-6)
Viruses strongly depend on the host cell for efficient replication and influenza A virus (IAV) amongst others also lead to remarkable changes of the host cell metabolism. The restriction of virus replication ... Tommaso Felicetti, etc.,al. Streamlined Synthesis and Structure–Activity Relationship Analysis of 2-Amidothiophene-3-Carboxamides Targeting Influenza Polymerase PA-PB1 Heterodimerization. ChemMedChem. Abstract
submitted by kickingbird at May, 25, 2026 from ChemMedChem (via https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002)
Influenza viruses remain a major global health threat due to their rapid evolution and ability to evade current therapies. Among viral targets, the PA–PB1 interface of the RNA polymerase complex has emerged ... Lee, C., Tarbuck, N.N., Cochran, H.J. et al. Dairy cows infected with influenza A(H5N1) reveals low infectious dose and transmission barriers. Nat Commun (2026). Abstract
submitted by kickingbird at May, 24, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-73490-6)
Highly pathogenic avian influenza A(H5N1) virus exhibits a strong tropism for the bovine mammary gland, challenging our understanding of influenza A virus host range and tissue specificity. We performed ... Salaheldin AH, Atasoy MO, Lang J, Ahrens AK, Pohlm. Molecular Characterization of H5N1 Clade 2.3.4.4B Virus in Vaccinated Layer Chickens. Viruses. 2026; 18(6):589. Abstract
submitted by kickingbird at May, 23, 2026 from Viruses. 2026; 18(6):589 (via https://www.mdpi.com/1999-4915/18/6/589)
The global emergence of the avian influenza virus (AIV) H5N1 clade 2.3.4.4B since 2016 has caused substantial losses in wild bird and poultry populations, along with heightened risks of transmission to ... Jinyan Shen, etc.,al. Genesis and biological features of H7 avian influenza viruses in migratory birds and implications for cross-species infection. Journal of Integrative Agriculture. Abstract
submitted by kickingbird at May, 23, 2026 from Journal of Integrative Agriculture (via https://www.sciencedirect.com/science/article/pii/S209531192)
H7 subtype avian influenza viruses (AIVs) pose a potential pandemic risk, as they can cause poultry outbreaks and spill over to mammals. H7 viruses harboured by migratory birds are recognized as progenitors ... Lauren E Steele, etc.,al. Age-specific mortality patterns across influenza pandemics: evidence from all-cause mortality data across multiple populations. International Journal of Epidemiology. Abstract
submitted by kickingbird at May, 22, 2026 from International Journal of Epidemiology (via https://academic.oup.com/ije/article/55/3/dyag061/8679000)
BackgroundUnderstanding age-specific mortality patterns across historic influenza pandemics is crucial for future pandemic preparedness. Prior research shows that, while the 1918 pandemic caused unprecedented ... Min Zhu, etc.,al. NS1-A53D enhances HA stability to coordinate viral entry with vRNP export and replication during adaptation of H1N1 canine influenza virus. Veterinary Microbiology. Abstract
submitted by kickingbird at May, 22, 2026 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Eurasian avian-like H1N1 influenza A viruses that have reassorted with the 2009 pandemic H1N1 virus pose a potential public health threat. We previously reported that synergistic mutations in HA and NS ... 7067 items, 20/Page, Page[11/354][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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