L. Olthof, K.C. Krogstad, B.J. Bradford. Cow-level factors associated with risk of clinical highly pathogenic avian influenza H5N1 infection and impacts on health and productivity in lactating dairy cattle. Journal of Dairy Science. Abstract
submitted by kickingbird at Jan, 2, 2026 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
As highly pathogenic avian influenza (HPAI) spreads in US dairy herds, substantial uncertainty remains regarding modes of transmission and net impacts on cattle health and productivity. The objectives ... Alekseev A, Sobolev I, Sharshov K, Gulyaeva M, Kur. Pathobiology of Highly Pathogenic Avian Influenza A (H5N1 Clade 2.3.4.4b) Virus from Pinnipeds on Tyuleniy Island in the Sea of Okhotsk, Russia. Viruses. 2026; 18(1):51. Abstract
submitted by kickingbird at Jan, 2, 2026 from Viruses. 2026; 18(1):51 (via https://www.mdpi.com/1999-4915/18/1/51)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b has recently emerged as a major threat to wildlife, agriculture, and public health due to its expanding host range and the increasing frequency ... Luo Y, Dong M, Shen Y, Xiang X, Lv J, Sun Y, Li Y,. Impact of viral Ribonucleoprotein Complex Genetic Stability on Pathogenicity in H9N2 and H6N2 Avian Influenza Viruses. Dev Comp Immunol. 2025 Dec 27:105544. Abstract
submitted by kickingbird at Dec, 31, 2025 from Dev Comp Immunol. 2025 Dec 27:105544 (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
China has a great demand for poultry, while avian influenza (AI) remains widespread and exhibits high instability, posing a persistent challenge to the poultry industry. Elucidating the genetic stability ... Rai, Kul Raj et al.. The long non-coding RNA MALAT1 encodes a micropeptide that promotes influenza A virus replication by suppressing innate immune responses. Journal of Biological Chemistry. Abstract
submitted by kickingbird at Dec, 31, 2025 from Journal of Biological Chemistry (via https://www.jbc.org/article/S0021-9258(25)02964-3/fulltext)
Long non-coding RNAs (lncRNAs) play critical roles in diverse biological processes and contain structurally distinct domains enabling multifunctional activity. Viral infections dynamically regulate lncRNA ... Wu, Y., Li, M., Li, H. et al. Cryo-EM structure of influenza polymerase bound to the cRNA promoter provides insights into the mechanism of viral replication. Commun Biol (2025). Abstract
submitted by kickingbird at Dec, 31, 2025 from Commun Biol (2025) (via https://www.nature.com/articles/s42003-025-09384-y)
Influenza virus polymerase (FluPol) synthesizes the complementary RNA (cRNA) and the viral RNA (vRNA) using distinct de novo initiation strategies during genome replication, known as internal and terminal ... Veldhuis Kroeze, E.J.B., Bellido Martin, B., Mols,. Pathology and virology of natural high pathogenicity avian influenza A(H5N1) Gs/GD genotype BB virus infection in wild black-headed gulls (Chroicocephalus ridibundus). Vet Res. 2025 Dec 29;56(1):234. Abstract
submitted by kickingbird at Dec, 31, 2025 from Vet Res. 2025 Dec 29;56(1):234 (via https://link.springer.com/article/10.1186/s13567-025-01666-x)
The ongoing worldwide outbreak of high pathogenicity avian influenza (HPAI) H5 of the Goose/Guangdong (Gs/GD) lineage has caused unprecedented mortality amongst an ever-expanding number of avian and mammalian ... Ward, J., Lambert, J.W., Russell, T.W. et al. Estimates of epidemiological parameters for H5N1 influenza in humans: a rapid review. BMC Infect Dis 25, 1755 (2025). Abstract
submitted by kickingbird at Dec, 31, 2025 from BMC Infect Dis 25, 1755 (2025) (via https://link.springer.com/article/10.1186/s12879-025-11933-z)
Background: The ongoing H5N1 panzootic in mammals has amplified zoonotic pathways to facilitate human infection. Characterising key epidemiological parameters for H5N1 is critical should it become widespread.Aim: ... Peng J, Miao X, Zhang X, Li Z, Wang Y, Liu G, Na L. Molecular Characterization of an H3N2 Canine Influenza Virus Isolated from a Dog in Jiangsu, China, in 2025. Veterinary Sciences. 2026; 13(1):32. Abstract
submitted by kickingbird at Dec, 31, 2025 from Veterinary Sciences. 2026; 13(1):32 (via https://www.mdpi.com/2306-7381/13/1/32)
To investigate the molecular characteristics of H3N2 canine influenza viruses circulating in Jiangsu, China, we isolated a H3N2 strain (A/Canine/Nanjing/CnNj01-2025) from a dog presenting with respiratory ... Alekseev A, Sobolev I, Sharshov K, Gulyaeva M, Kur. Pathobiology of Highly Pathogenic Avian Influenza A (H5N1 Clade 2.3.4.4b) Virus from Pinnipeds on Tyuleniy Island in the Sea of Okhotsk, Russia. Viruses. 2026; 18(1):51. Abstract
submitted by kickingbird at Dec, 31, 2025 from Viruses. 2026; 18(1):51 (via https://www.mdpi.com/1999-4915/18/1/51)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b has recently emerged as a major threat to wildlife, agriculture, and public health due to its expanding host range and the increasing frequency ... Yuwen Luo, etc.,al. Impact of viral Ribonucleoprotein Complex Genetic Stability on Pathogenicity in H9N2 and H6N2 Avian Influenza Viruses. Developmental & Comparative Immunology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Developmental & Comparative Immunology (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
China has a great demand for poultry, while avian influenza (AI) remains widespread and exhibits high instability, posing a persistent challenge to the poultry industry. Elucidating the genetic stability ... Harrell T.L., Shwani A., Suarez D.L. The Impact of Acids, pH, and Incubation Time on Avian Influenza Virus Persistence in Raw Milk. Food Microbiology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Food Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S07400)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4.b H5N1 was detected in dairy cattle. Since detection, the virus has spread across 17 states, infecting more than 1000 dairy ... Ane Marie Anderson, etc.,al. DNA vaccines targeting hemagglutinin from 18 subtypes of influenza A virus to antigen presenting cells confer broad protection. Molecular Therapy Nucleic Acids. Abstract
submitted by kickingbird at Dec, 28, 2025 from Molecular Therapy Nucleic Acids (via https://www.sciencedirect.com/science/article/pii/S216225312)
Novel vaccines that confer broad protection against influenza A viruses (IAV) are urgently needed. Hemagglutinin (HA) is the major influenza antigen targeted by protective immune responses. We have here ... Zhu, T., Zhu, M., Lu, F. et al. Pre-activation timing determines influenza severity and viral pathogenicity via STING Inhibition. Sci Rep 15, 44501 (2025). Abstract
submitted by kickingbird at Dec, 28, 2025 from Sci Rep 15, 44501 (2025) (via https://www.nature.com/articles/s41598-025-28063-w)
Severe influenza is frequently associated with bacterial or viral co-infections. Although immune-mediated mechanisms have been extensively investigated, the cell-intrinsic responses of respiratory epithelial ... Yang G, Chen P-L, Rovito SW, Minari K, Writt HN, D. Resistance Mutations to Broadly Neutralizing Antibodies Destabilize Hemagglutinin and Attenuate H1N1 Influenza Virus. Viruses. 2026; 18(1):32. Abstract
submitted by kickingbird at Dec, 25, 2025 from Viruses. 2026; 18(1):32 (via https://www.mdpi.com/1999-4915/18/1/32)
Because antigenic drift primarily generates amino-acid changes in the membrane-distal hemagglutinin (HA) head, broadly neutralizing antibodies (bNAbs) are being developed to target conserved epitopes in ... Mengdi Guan, etc.,al. Genetic diversity of H13 avian influenza viruses in migratory shorebirds in eastern China. Journal of Integrative Agriculture. Abstract
submitted by kickingbird at Dec, 25, 2025 from Journal of Integrative Agriculture (via https://www.sciencedirect.com/science/article/pii/S209531192)
Highlights1.Twenty one H13 subtype avian influenza viruses were isolated from 50016 samples in migratory birds during 2017 to 2024 in Shandong Province, China2.The H13 viruses were mainly harbored by shorebirds ... Alvin Crespo-Bellido, etc.,al. [preprint]Emergence of D1.1 reassortant H5N1 avian influenza viruses in North America. https://doi.org/10.64898/2025.12.19.695329. Abstract
submitted by kickingbird at Dec, 24, 2025 from https://doi.org/10.64898/2025.12.19.695329 (via https://www.biorxiv.org/content/10.64898/2025.12.19.695329v1)
Since 2021, highly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality in North American wild birds and poultry. In 2025, a new D1.1 genotype caused two ... Song Y, Yan A, Song S, Gong H, Chen L, Fu B, Zhang. Phylogenetic Analyses and Biological Characterization of H9N2 Avian Influenza Virus Isolated from Chickens in China from 2022 to 2023. Microorganisms. 2026; 14(1):37. Abstract
submitted by kickingbird at Dec, 24, 2025 from Microorganisms. 2026; 14(1):37 (via https://www.mdpi.com/2076-2607/14/1/37)
The continued diversification of the H9N2 avian influenza virus (AIV) into multiple antigenically and phylogenetically distinct lineages is promoting the emergence of strains with pandemic potential. Constant ... Schmierer J, Lutz M, Takimoto T. 0. Enhanced genome replication activity of pandemic H1N1 influenza A virus through PA mutations. J Virol 0:e01391-25. Abstract
submitted by kickingbird at Dec, 24, 2025 from J Virol 0:e01391-25 (via https://journals.asm.org/doi/10.1128/jvi.01391-25)
The 2009 pandemic H1N1 (pH1N1) influenza A virus (IAV) is a reassortant virus with two polymerase components, PA and PB2, originating from avian IAV. Avian IAV polymerase does not function efficiently ... Jeffery D. Sullivan, etc.,al. Rapid increase in antibodies to influenza A virus H5 and N1 in Lesser Scaup (Aythya affinis) following the introduction of 2.3.4.4b H5N1 into North America. Canadian Journal of Microbiology. Abstract
submitted by kickingbird at Dec, 24, 2025 from Canadian Journal of Microbiology (via https://www.sciencedirect.com/org/science/article/pii/S00084)
Clade 2.3.4.4b Eurasian-origin H5N1 entered North America in late 2021 and spread across the continent. While studies have characterized the antibody response mounted by dabbling ducks following exposure, ... Shu Zhou, Rute Maria Pinto, Hou Wei Chook, Eleanor. [preprint]Identification of cis-Acting Elements that Regulate Influenza A Virus Segment 7 Differential mRNA Splicing. https://doi.org/10.64898/2025.12.22.695654. Abstract
submitted by kickingbird at Dec, 23, 2025 from https://doi.org/10.64898/2025.12.22.695654 (via https://www.biorxiv.org/content/10.64898/2025.12.22.695654v1)
Influenza A virus segment 7 encodes the M1 matrix protein and M2 ion channel from an unspliced primary transcript mRNA1 and spliced mRNA2, respectively. Both proteins are essential for efficient virus ... 6712 items, 20/Page, Page[10/336][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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