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2026-10-7 13:43:12
Article

Brendan Flannery, Jessie R Chung, Crystal Holiday,. Influenza Antibody Levels Associated with Laboratory-Confirmed Influenza in a Test-Negative Study Design, US Flu VE Network, November 2018–May 2019. The Journal of Infectious Diseases, 2026.  Abstract  
submitted by kickingbird at Jul, 22, 2026 from The Journal of Infectious Diseases, 2026 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
BackgroundWe assessed associations between antibody concentrations within 7 days of symptom onset and testing positive for influenza virus infection among outpatients enrolled in a test-negative study.MethodsFrom ...

Kotova, I., Mühlberg, L., Gilep, K. et al. Mapping in-cell protein contact sites reveals hijacking of paraspeckles during influenza A virus infection. Nat Microbiol (2026).  Abstract  
submitted by kickingbird at Jul, 22, 2026 from Nat Microbiol (2026) (via https://link.springer.com/article/10.1038/s41564-026-02416-1)
Influenza A virus (IAV) hijacks host cellular machinery during infection but many host–virus protein interactions remain uncharacterized, particularly in their native context. Here, we applied in-cell ...

Ruonan Liang, etc.,al. [preprint]Loss of hemagglutination ability by H3N2 influenza A virus, subclade K. https://doi.org/10.64898/2026.07.20.739523.  Abstract  
submitted by kickingbird at Jul, 22, 2026 from https://doi.org/10.64898/2026.07.20.739523 (via https://www.biorxiv.org/content/10.64898/2026.07.20.739523v1)
Seasonal human H3N2 influenza viruses, subclade K (J.2.4.1), have been the predominant influenza A viruses in the Northern hemisphere influenza season of 2025/2026. Since 2024, the vaccine virus A/Darwin/6/21 ...

Chen, D., Wei, H., Zhang, Y. et al. Identification of two novel B-cell epitopes targeting the hemagglutinin protein of H9N2 avian influenza virus. Animal Diseases 6, 47 (2026).  Abstract  
submitted by kickingbird at Jul, 22, 2026 from Animal Diseases 6, 47 (2026) (via https://link.springer.com/article/10.1186/s44149-026-00261-7)
H9N2 avian influenza virus (AIV) remains a global threat to poultry health and has zoonotic potential. Antigenic drift in the hemagglutinin (HA) protein complicates vaccine efficacy and diagnostic accuracy, ...

Cianciulli A, Santoro E, Esposito S, Quaglierella. Genomic and Antigenic Evolution of Influenza A(H3N2) After the COVID-19 Era: A Scoping Review with Focus on J and K Subclades and Implications for Vaccine Effectiveness. Germs. 2026; 16(3):1.  Abstract  
submitted by kickingbird at Jul, 21, 2026 from Germs. 2026; 16(3):1 (via https://www.mdpi.com/2248-2997/16/3/18)
Post-COVID-19, influenza A(H3N2) has re-emerged with accelerated genetic diversification. The rise in antigenically drifted subclades raises concerns regarding immune escape and vaccine mismatch. To synthesize ...

Min Liu, etc.,al. [preprint]Bovine-derived H5N1 influenza virus efficiently infects lactating swine via the mammary gland. https://doi.org/10.64898/2026.07.18.739312.  Abstract  
submitted by kickingbird at Jul, 20, 2026 from https://doi.org/10.64898/2026.07.18.739312 (via https://www.biorxiv.org/content/10.64898/2026.07.18.739312v1)
Since 2024, highly pathogenic influenza A(H5N1) viruses have spread extensively among U.S. dairy cattle, where they replicate efficiently in the mammary gland and are shed at high titers in milk. To directly ...

Shaoyu Tu, etc.,al. [preprint]Lactylation of Influenza Virus Polymerase Acidic Protein Promotes Viral Replication and Pathogenicity. https://doi.org/10.64898/2026.07.10.737663.  Abstract  
submitted by kickingbird at Jul, 18, 2026 from https://doi.org/10.64898/2026.07.10.737663 (via https://www.biorxiv.org/content/10.64898/2026.07.10.737663v1)
Influenza virus poses a potential risk of triggering the next global pandemic. In-depth investigation into the mechanisms underlying influenza virus replication and pathogenicity will provide robust support ...

Wang, L., Xu, H., Li, J. et al. In vitro and in vivo studies of GAPLINC identify it as a critical host factor involved in the regulation of influenza A virus infection. Vet Res 57, 136 (2026).  Abstract  
submitted by kickingbird at Jul, 18, 2026 from Vet Res 57, 136 (2026) (via https://link.springer.com/article/10.1186/s13567-026-01783-1)
Although previous studies have suggested a role for GAPLINC in regulating influenza A virus (IAV) infection, the functional involvement of GAPLINC in IAV infection in vitro and in vivo remains largely ...

B. Ruan, C. Liang, M. Hu, et al. Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice. Advanced Science (2026): e76669.  Abstract  
submitted by kickingbird at Jul, 18, 2026 from Advanced Science (2026): e76669 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76)
Influenza, which causes respiratory tract infections and related complications, poses a major threat to global public health. However, the rapid and accurate detection of influenza viruses in controlling ...

Ahlstrom, C.A., Scott, L.C., Reeves, A.B. et al. Ecological shifts in avian influenza viruses following HPAIV introductions in southwestern Alaska, 2011-2024. npj Viruses (2026).  Abstract  
submitted by kickingbird at Jul, 18, 2026 from npj Viruses (2026) (via https://www.nature.com/articles/s44298-026-00212-6)
Southwestern Alaska wetlands are critical staging habitats for migratory waterfowl that breed in western North America and East Asia. Since 2011, samples originating from hunter-harvested waterfowl and ...

Brock N, Zeng H, Pappas C, Kieran TJ, Sun X, Pulit. Cellular tropism of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b viruses in human respiratory and bovine mammary epithelial cells. Microbiol Spectr 0:e01377-26.  Abstract  
submitted by kickingbird at Jul, 18, 2026 from Microbiol Spectr 0:e01377-26 (via https://journals.asm.org/doi/10.1128/spectrum.01377-26)
The recent introduction and spread of HPAI A(H5N1) clade 2.3.4.4b viruses to U.S. dairy cattle demonstrate their ability to adapt to new mammalian hosts. Although multiple A(H5N1) genotypes have caused ...

Prantner D, Qi X, Villaneuva LM, Paton J, Blanco J. The signaling adaptor insulin receptor substrate 2 (IRS2) limits lethal host responses induced by influenza infection. Innate Immun. 2026 Jan-Dec;32:17534259261469305.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Innate Immun. 2026 Jan-Dec;32:17534259261469305 (via https://journals.sagepub.com/doi/10.1177/17534259261469305)
Influenza is a highly contagious virus with most individuals showing recovery within a week after symptom onset. However, children, the elderly, and those with chronic health conditions are at high risk ...

Da Silva K, Naffakh N, Rameix-Welti MA, Lemoine F. Accounting for Defective Viral Genomes in viral consensus genome reconstruction, application to influenza virus. PLoS Comput Biol. 2026 Jul 16;22(7):e1014115.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from PLoS Comput Biol. 2026 Jul 16;22(7):e1014115 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
In the context of viral epidemic surveillance, generating accurate consensus viral genomes from sequencing data is critical for tracking the emergence of mutations of concern, evaluating the genomic diversity ...

Chen Y, Ankerhold J, Jia T, Wolkewitz M, Fuchs J,. Autoantibodies against type I interferons in patients with zoonotic H7N9 influenza: an observational case-control study. EBioMedicine. 2026 Jul 16;130:106387.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from EBioMedicine. 2026 Jul 16;130:106387 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The determinants of the species barrier preventing human infections with avian influenza A viruses (IAV) are incompletely understood. We previously identified loss-of-function variants of the ...

Han Yan, etc.,al. [preprint]Antibodies against influenza A/H1N1pdm2009 and B/Victoria strains but not A/H3N2 are increased in recent onset type 1 narcolepsy versus matched controls. https://doi.org/10.64898/2026.06.13.26355596.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from https://doi.org/10.64898/2026.06.13.26355596 (via https://www.medrxiv.org/content/10.64898/2026.06.13.26355596)
Study Objectives Onsets of Narcolepsy type-1 (NT1) increased following A/H1N1 vaccination with Pandemrix? in Europe and with A/H1N1pdm2009 infections in China and other countries. To test if other strains ...

Ciminski K, Reuther P, Rijkers R, de Vries RP, Sch. The receptor landscape of influenza A viruses. J Virol 0:e01443-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e01443-25 (via https://journals.asm.org/doi/10.1128/jvi.01443-25)
Influenza A viruses (IAVs) have a remarkable ability to adapt to new host species, which has been attributed to the specificity of the viral hemagglutinin (HA) for sialylated glycans and the functional ...

Shirazi R, Kim SY, Cruz A, Stumpff JP, Sveiven SN,. RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cells. J Virol 0:e02225-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e02225-25 (via https://journals.asm.org/doi/10.1128/jvi.02225-25)
Beyond a physical barrier, the lung epithelium provides an essential line of defense against infectious pathogens, such as influenza A viruses (IAVs), by producing antimicrobial factors and triggering ...

Kubacki J, Renzullo S, Miller-Collmann N, Lale D,. Genome sequence of a Florida Clade 1 case of equine influenza in Switzerland. Microbiol Resour Announc 0:e00635-26.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Microbiol Resour Announc 0:e00635-26 (via https://journals.asm.org/doi/10.1128/mra.00635-26)
Here, we report the whole-genome sequence of A/Equus caballus/Zuerich/260760/2026, an equine influenza virus (H3N8) belonging to Florida Clade 1, detected in Switzerland following increased reports of ...

Snyder CA, Janzen GM, Zanella GC, Moraes DCA, Silv. Occupationally Exposed and General Population Antibody Profiles to Influenza A Viruses Circulating in Swine as Indication of Zoonotic Risk. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1995_article)
Persons with occupational exposure to swine might be at disproportionate risk for zoonotic swine influenza A virus. To evaluate human antibody responses, we tested serum or plasma from swine veterinarian, ...

Seger H, Baker AL, Buckley AC, Anderson TK, Markin. Detection of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Genotype D1.2 Virus in Swine after Experimental Inoculation. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1765_article)
Highly pathogenic avian influenza H5NX clade 2.3.4.4b viruses continue to circulate globally. Reintroduction of Eurasian lineage viruses into North America and reassortment with endemic low pathogenicity ...

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