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Osthus D, Daughton AR, Priedhorsky R. Even a good influenza forecasting model can benefit from internet-based nowcasts, but those benefits are limited. PLoS Comput Biol. 2019 Feb 1;15(2):e1006599..  Abstract  
submitted by kickingbird at Feb, 3, 2019 from PLoS Comput Biol. 2019 Feb 1;15(2):e1006599. (via https://www.ncbi.nlm.nih.gov/pubmed/30707689)
The ability to produce timely and accurate flu forecasts in the United States can significantly impact public health. Augmenting forecasts with internet data has shown promise for improving forecast accuracy ...

Yang CY, Chen RJ, Chou WL, Lee YJ, Lo YS. An Integrated Influenza Surveillance Framework Based on National Influenza-Like Illness Incidence and Multiple Hospital Electronic Medical Records for Early Prediction of Influenza Epidemics: Design a. J Med Internet Res. 2019 Feb 1;21(2):e12341.  Abstract  
submitted by kickingbird at Feb, 3, 2019 from J Med Internet Res. 2019 Feb 1;21(2):e12341 (via https://www.ncbi.nlm.nih.gov/pubmed/30707099)
BACKGROUND: Influenza is a leading cause of death worldwide and contributes to heavy economic losses to individuals and communities. Therefore, the early prediction of and interventions against influenza ...

Tellier R, Li Y, Cowling BJ, Tang JW. Recognition of aerosol transmission of infectious agents: a commentary. BMC Infect Dis. 2019 Jan 31;19(1):101.  Abstract  
submitted by kickingbird at Feb, 3, 2019 from BMC Infect Dis. 2019 Jan 31;19(1):101 (via https://www.ncbi.nlm.nih.gov/pubmed/30704406)
Although short-range large-droplet transmission is possible for most respiratory infectious agents, deciding on whether the same agent is also airborne has a potentially huge impact on the types (and costs) ...

Yamayoshi S, Kawaoka Y. Current and future influenza vaccines. Nat Med. 2019 Jan 28.  Abstract  
submitted by kickingbird at Jan, 31, 2019 from Nat Med. 2019 Jan 28 (via https://www.ncbi.nlm.nih.gov/pubmed/30692696)
Although antiviral drugs and vaccines have reduced the economic and healthcare burdens of influenza, influenza epidemics continue to take a toll. Over the past decade, research on influenza viruses has ...

Simon B, et al. Whole Genome Sequencing of A(H3N2) Influenza Viruses Reveals Variants Associated with Severity during the 2016~2017 Season. Viruses. 2019 Jan 28;11(2).  Abstract  
submitted by kickingbird at Jan, 31, 2019 from Viruses. 2019 Jan 28;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30695992)
Influenza viruses cause a remarkable disease burden and significant morbidity and mortality worldwide, and these impacts vary between seasons. To understand the mechanisms associated with these differences, ...

Ohkusa Y, et al. Inquiry into some gap among oseltamivir use and severe abnormal behavior in Japanese children and adolescents with influenza. Drug Discov Ther. 2018;12(6):381-383.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from Drug Discov Ther. 2018;12(6):381-383 (via https://www.ncbi.nlm.nih.gov/pubmed/30674775)
The Fukushima research has examined data form a cohort study of 10,000 Japanese children under 18 years old with influenza during three months to demonstrate that the relative risk of A-type abnormal behavior ...

Takashita E, et al. Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018. Euro Surveill. 2019 Jan;24(3)..  Abstract  
submitted by kickingbird at Jan, 26, 2019 from Euro Surveill. 2019 Jan;24(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30670142)
The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution ...

Koutsakos M, Kedzierska K, Subbarao K. Immune Responses to Avian Influenza Viruses. J Immunol. 2019 Jan 15;202(2):382-391..  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Immunol. 2019 Jan 15;202(2):382-391. (via https://www.ncbi.nlm.nih.gov/pubmed/30617120)
Avian influenza A viruses (IAVs) naturally infect different avian species, and aquatic birds are their natural reservoir. Sporadically, avian IAVs can be transmitted to humans, and some, such as H5N1 and ...

Hatayama K, et al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2019 Mar;91(3):361-369..  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Med Virol. 2019 Mar;91(3):361-369. (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury due to the excessive inflammatory reaction, even with neuraminidase inhibitor use. The ...

Yang Y, et al. Comparison between human infections caused by highly and low pathogenic H7N9 avian influenza viruses in Wave Five: clinical and virological findings. J Infect. 2019 Jan 18.  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Infect. 2019 Jan 18 (via https://www.ncbi.nlm.nih.gov/pubmed/30664912)
OBJECTIVE: The newly emerged highly pathogenic (HP) H7N9 avian influenza virus during Wave Five has caused 28 human infections, while differences in disease severity between low pathogenic (LP)- and HP-H7N9 ...

Parra-Rojas C, Messling VV, Hernandez-Vargas EA. Adjuvanted influenza vaccine dynamics. Sci Rep. 2019 Jan 11;9(1):73.  Abstract  
submitted by kickingbird at Jan, 15, 2019 from Sci Rep. 2019 Jan 11;9(1):73 (via https://www.ncbi.nlm.nih.gov/pubmed/30635599)
Adjuvanted influenza vaccines constitute a key element towards inducing neutralizing antibody responses in populations with reduced responsiveness, such as infants and elderly subjects, as well as in devising ...

Lu FS, Hattab MW, Clemente CL, et al. Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches. Nat Commun. 2019 Jan 11;10(1):147.  Abstract  
submitted by kickingbird at Jan, 14, 2019 from Nat Commun. 2019 Jan 11;10(1):147 (via https://www.ncbi.nlm.nih.gov/pubmed/30635558)
In the presence of health threats, precision public health approaches aim to provide targeted, timely, and population-specific interventions. Accurate surveillance methodologies that can estimate infectious ...

Lu C, Xing Y, Cai H, Shi Y, Liu J, Huang Y. Identification and analysis of long non-coding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos). BMC Genomics. 2019 Jan 11.  Abstract  
submitted by kickingbird at Jan, 14, 2019 from BMC Genomics. 2019 Jan 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30634898)
BACKGROUND: Long non-coding RNAs (lncRNAs) are important component of mammalian genomes, where their numbers are even larger than that of protein-coding genes. For example, human (Homo sapiens) (96,308 ...

Chastagner A, et al. Spatiotemporal Distribution and Evolution of the A/H1N1 2009 Pandemic Influenza Virus in Pigs in France from 2009 to 2017: Identification of a Potential Swine-Specific Lineage. J Virol. 2018 Nov 27;92(24).  Abstract  
submitted by kickingbird at Jan, 14, 2019 from J Virol. 2018 Nov 27;92(24) (via https://www.ncbi.nlm.nih.gov/pubmed/30258006)
The H1N1 influenza virus responsible for the most recent pandemic in 2009 (H1N1pdm) has spread to swine populations worldwide while it replaced the previous seasonal H1N1 virus in humans. In France, surveillance ...

Htwe KTZ, et al. Phylogeographic analysis of human influenza A and B viruses in Myanmar, 2010-2015. PLoS One. 2019 Jan 10;14(1):e0210550.  Abstract  
submitted by kickingbird at Jan, 14, 2019 from PLoS One. 2019 Jan 10;14(1):e0210550 (via https://www.ncbi.nlm.nih.gov/pubmed/30629691)
We investigated the circulation patterns of human influenza A and B viruses in Myanmar between 2010 and 2015 by analyzing full HA genes. Upper respiratory tract specimens were collected from patients with ...

Martínez A, et al. Risk factors associated with severe outcomes in adult hospitalized patients according to influenza type and subtype. PLoS One. 2019 Jan 11;14(1):e0210353.  Abstract  
submitted by kickingbird at Jan, 14, 2019 from PLoS One. 2019 Jan 11;14(1):e0210353 (via https://www.ncbi.nlm.nih.gov/pubmed/30633778)
Seasonal influenza is a cause of hospitalization, especially in people with underlying disease or extreme age, and its severity may differ depending on the types and subtypes of circulating viruses. We ...

Gounder AP, Boon ACM. Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease. J Immunol. 2019 Jan 15;202(2):341-350..  Abstract  
submitted by kickingbird at Jan, 9, 2019 from J Immunol. 2019 Jan 15;202(2):341-350. (via https://www.ncbi.nlm.nih.gov/pubmed/30617115)
Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject ...

Berger KA, et al. The Geographic Variation of Surveillance and Zoonotic Spillover Potential of Influenza Viruses in Domestic Poultry and Swine. Open Forum Infect Dis. 2018 Nov 27.  Abstract  
submitted by kickingbird at Jan, 9, 2019 from Open Forum Infect Dis. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30619908)
Background: Avian and swine influenza viruses circulate worldwide and pose threats to both animal and human health. The design of global surveillance strategies is hindered by information gaps on the geospatial ...

Peci A, et al. Effect of absolute and relative humidity, temperature and wind speed on influenza activity in Toronto, Canada. Appl Environ Microbiol. 2019 Jan 4.  Abstract  
submitted by kickingbird at Jan, 7, 2019 from Appl Environ Microbiol. 2019 Jan 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30610079)
The occurrence of influenza in different climates is shown to be associated with multiple meteorological factors. Incidence of influenza has been reported to increase during rainy seasons in tropical climates ...

Peretz A, Azrad M, Blum A. Influenza virus and Atherosclerosis. QJM. 2019 Jan 3..  Abstract  
submitted by kickingbird at Jan, 7, 2019 from QJM. 2019 Jan 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30605546)
Influenza viruses infect the upper respiratory system, causing usually a self-limited disease with mild respiratory symptoms. Acute lung injury, pulmonary microvascular leakage and cardiovascular collapse ...

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