Tian J, Li M, Li Y, Bai X, Song X, Zhao Z, Ge S, L. H3N8 subtype avian influenza virus originated from wild birds exhibited dual receptor-binding profiles. J Infect. 2022 Oct 20:S0163-4453(22)00622-3
We present the phylogeny, receptor binding property, growth in mammal cells and pathogenicity in mammal model of H3N8 viruses, which were isolated from wild birds in China. The human receptor preference and efficient replication in mice without prior adaption highlight that the H3N8 virus possesses the public threat potential.
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